BE856039A - Bis(3,50dicarbamoyl-2,4-triiodoanilides)d'acide dicarboxylique et leurs intermediaires, leur preparation et utilisation - Google Patents
Bis(3,50dicarbamoyl-2,4-triiodoanilides)d'acide dicarboxylique et leurs intermediaires, leur preparation et utilisationInfo
- Publication number
- BE856039A BE856039A BE178719A BE178719A BE856039A BE 856039 A BE856039 A BE 856039A BE 178719 A BE178719 A BE 178719A BE 178719 A BE178719 A BE 178719A BE 856039 A BE856039 A BE 856039A
- Authority
- BE
- Belgium
- Prior art keywords
- triiodoanilides
- intermediaries
- bis
- preparation
- dicarboxylic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polyesters Or Polycarbonates (AREA)
- Medicinal Preparation (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2628517A DE2628517C2 (de) | 1976-06-23 | 1976-06-23 | Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel |
Publications (1)
Publication Number | Publication Date |
---|---|
BE856039A true BE856039A (fr) | 1977-12-23 |
Family
ID=5981407
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE178719A BE856039A (fr) | 1976-06-23 | 1977-06-23 | Bis(3,50dicarbamoyl-2,4-triiodoanilides)d'acide dicarboxylique et leurs intermediaires, leur preparation et utilisation |
Country Status (28)
Country | Link |
---|---|
US (1) | US4239747A (fr) |
JP (2) | JPS537637A (fr) |
AT (1) | AT361117B (fr) |
AU (1) | AU512304B2 (fr) |
BE (1) | BE856039A (fr) |
CA (2) | CA1106400A (fr) |
CH (1) | CH629751A5 (fr) |
CS (1) | CS199680B2 (fr) |
DD (1) | DD131014A5 (fr) |
DE (1) | DE2628517C2 (fr) |
DK (2) | DK150505C (fr) |
ES (1) | ES460007A1 (fr) |
FI (1) | FI67540C (fr) |
FR (1) | FR2355808A1 (fr) |
GB (2) | GB1588734A (fr) |
GR (1) | GR71696B (fr) |
HU (1) | HU174228B (fr) |
IE (2) | IE45225B1 (fr) |
IL (2) | IL52356A (fr) |
IT (1) | IT1237314B (fr) |
LU (2) | LU77588A1 (fr) |
NL (1) | NL189510C (fr) |
NO (2) | NO147447C (fr) |
PL (1) | PL108102B1 (fr) |
PT (1) | PT66690B (fr) |
SE (1) | SE436871B (fr) |
SU (1) | SU917696A3 (fr) |
ZA (1) | ZA773782B (fr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH626873A5 (fr) * | 1977-03-28 | 1981-12-15 | Bracco Ind Chimica Spa | |
DK273280A (da) * | 1979-06-28 | 1980-12-29 | Schering Ag | Trijoderede 5-aminoisophthalsyrederivater |
IT1193211B (it) * | 1979-08-09 | 1988-06-15 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono |
IT1207226B (it) * | 1979-08-09 | 1989-05-17 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono. |
JPS56127373A (en) * | 1980-01-31 | 1981-10-06 | Univ California | Novel amino-dioxepane intermediate for synthesizing novel nonionic contrast agent |
US4341756A (en) * | 1980-01-31 | 1982-07-27 | The Regents Of The University Of California | Novel amino-dioxepane intermediates for the synthesis of new non-ionic contrast media |
DE3038853A1 (de) * | 1980-10-10 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii) |
DE3364536D1 (en) * | 1982-11-08 | 1986-08-21 | Nyegaard & Co As | X-ray contrast agents |
FR2541272A1 (fr) * | 1983-02-23 | 1984-08-24 | Guerbet Sa | Composes bromes et produits opacifiants en contenant |
US4650903A (en) * | 1984-06-21 | 1987-03-17 | The Bf Goodrich Company | Oligomeric amides as synergists for antioxidants and UV stabilizers |
DE3731542A1 (de) * | 1987-09-17 | 1989-03-30 | Schering Ag | Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel |
DE3739098A1 (de) * | 1987-11-16 | 1989-05-24 | Schering Ag | Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel |
US5075502A (en) * | 1989-12-13 | 1991-12-24 | Mallinckrodt, Inc. | Nonionic x-ray contrast agents, compositions and methods |
IT1252180B (it) * | 1991-12-10 | 1995-06-05 | Bracco Ind Chimica Spa | 5,5'-(1,3-propandiil) bis (imino (2-osso-2,1-etandiil)acetilimino)-bis(2,4,6-triiodo-1,3-benzendicarbossiamidi),loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono |
CN1038725C (zh) * | 1993-12-04 | 1998-06-17 | 吉林省鹊源国际生物工程有限公司 | 复方天然香菇营养液 |
US6149891A (en) * | 1995-05-31 | 2000-11-21 | Israel Humanitarian Foundation Ltd. | X-ray contrast medium and method for protecting against harmful effects thereof |
IT1299202B1 (it) * | 1998-05-08 | 2000-02-29 | Dibra Spa | Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo |
US7790141B2 (en) * | 2003-08-11 | 2010-09-07 | Pathak Holdings, Llc | Radio-opaque compounds, compositions containing same and methods of their synthesis and use |
CA2692646C (fr) | 2007-07-12 | 2014-09-09 | Mikkel Thaning | Produits de contraste |
WO2009047315A1 (fr) | 2007-10-12 | 2009-04-16 | Ge Healthcare As | Produits de contraste |
US20100221192A1 (en) | 2007-10-12 | 2010-09-02 | Duncan George Wynn | Contrast agents |
US8202511B2 (en) | 2007-10-12 | 2012-06-19 | Ge Healthcare As | Contrast agents |
JP2011500531A (ja) | 2007-10-12 | 2011-01-06 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 造影剤 |
US8551449B2 (en) * | 2007-10-30 | 2013-10-08 | Ge Healthcare As | Contrast agents |
EP2240432B1 (fr) * | 2008-01-14 | 2012-07-04 | Mallinckrodt LLC | Procédé pour la préparation d'iosiménol |
WO2012136813A2 (fr) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents pour un diagnostic par radar médical |
US11065201B2 (en) | 2014-11-21 | 2021-07-20 | Technical University Of Denmark | Gel formulations for local drug release |
SG11201809729XA (en) | 2016-05-20 | 2018-12-28 | Univ Denmark Tech Dtu | Palpable marker composition |
WO2020249801A1 (fr) | 2019-06-12 | 2020-12-17 | Technical University Of Denmark | Formulations de disaccharides pour la libération contrôlée de médicaments |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2853424A (en) * | 1952-08-06 | 1958-09-23 | Schering Ag | X-ray contrast agents comprising symmetrical bifunctional analogs of nu-acyl derivatives of 2, 4, 6 triiodo-3-amino benzoic acid |
US3178473A (en) * | 1962-03-02 | 1965-04-13 | Nyegaard & Co As | Process for the n-alkylation of acyl anilides halogen substituted in the nucleus |
US3290366A (en) * | 1963-03-06 | 1966-12-06 | Mallinckrodt Chemical Works | 5-amino-nu-alkyl-2, 4, 6-triiodoisophthalamic acid derivatives |
GB1033777A (en) * | 1963-06-06 | 1966-06-22 | Sterling Drug Inc | Bis-anilide derivatives |
US3732293A (en) * | 1968-03-15 | 1973-05-08 | Sterling Drug Inc | Iodinated bis(aminobenzoic acids) and esters thereof |
CH502104A (de) * | 1968-05-02 | 1971-01-31 | Bracco Ind Chimica Spa | Neue Röntgenkontrastmittel und Verfahren zu ihrer Herstellung |
BE752574A (fr) * | 1969-06-27 | 1970-12-28 | Nyegaard & Co As | Agents de contraste aux rayons-x iodes |
US3660464A (en) * | 1970-06-19 | 1972-05-02 | Squibb & Sons Inc | Tri-iodinated diaminobenzoic acid derivatives |
BE787669A (fr) * | 1971-08-17 | 1973-02-19 | Schering Ag | Anilides d'acide n-methyl-dicarboxylique triiodes, et leur procede de preparation |
DD104193A5 (fr) * | 1972-12-22 | 1974-03-05 | ||
DE2629228C2 (de) * | 1976-06-25 | 1984-10-18 | Schering AG, 1000 Berlin und 4709 Bergkamen | Jodierte Isophthalamsäure-Derivate Verfahren zu deren Herstellung sowie deren Verwendung |
CH626873A5 (fr) * | 1977-03-28 | 1981-12-15 | Bracco Ind Chimica Spa |
-
1976
- 1976-06-23 DE DE2628517A patent/DE2628517C2/de not_active Expired
-
1977
- 1977-05-18 NL NLAANVRAGE7705509,A patent/NL189510C/xx not_active IP Right Cessation
- 1977-06-16 FI FI771900A patent/FI67540C/fi not_active IP Right Cessation
- 1977-06-16 DK DK266177A patent/DK150505C/da not_active IP Right Cessation
- 1977-06-20 GB GB7222/80A patent/GB1588734A/en not_active Expired
- 1977-06-20 CS CS774059A patent/CS199680B2/cs unknown
- 1977-06-20 PL PL1977199019A patent/PL108102B1/pl not_active IP Right Cessation
- 1977-06-20 IE IE1249/77A patent/IE45225B1/en not_active IP Right Cessation
- 1977-06-20 GB GB25644/77A patent/GB1588733A/en not_active Expired
- 1977-06-21 LU LU77588A patent/LU77588A1/xx unknown
- 1977-06-21 PT PT66690A patent/PT66690B/pt unknown
- 1977-06-21 GR GR53760A patent/GR71696B/el unknown
- 1977-06-21 IL IL52356A patent/IL52356A/xx unknown
- 1977-06-21 DD DD7700199616A patent/DD131014A5/xx unknown
- 1977-06-21 CH CH761277A patent/CH629751A5/de not_active IP Right Cessation
- 1977-06-22 SE SE7707230A patent/SE436871B/xx not_active IP Right Cessation
- 1977-06-22 SU SU772498151A patent/SU917696A3/ru active
- 1977-06-22 NO NO772202A patent/NO147447C/no unknown
- 1977-06-22 HU HU77SCHE611A patent/HU174228B/hu unknown
- 1977-06-22 CA CA281,184A patent/CA1106400A/fr not_active Expired
- 1977-06-22 ES ES460007A patent/ES460007A1/es not_active Expired
- 1977-06-22 AU AU26325/77A patent/AU512304B2/en not_active Expired
- 1977-06-23 BE BE178719A patent/BE856039A/fr not_active IP Right Cessation
- 1977-06-23 JP JP7489777A patent/JPS537637A/ja active Granted
- 1977-06-23 AT AT443777A patent/AT361117B/de not_active IP Right Cessation
- 1977-06-23 ZA ZA00773782A patent/ZA773782B/xx unknown
- 1977-06-23 FR FR7719234A patent/FR2355808A1/fr active Granted
- 1977-06-23 IT IT7724994A patent/IT1237314B/it active
-
1979
- 1979-01-12 US US06/002,901 patent/US4239747A/en not_active Expired - Lifetime
-
1980
- 1980-03-21 CA CA348,166A patent/CA1106401A/fr not_active Expired
- 1980-06-18 IL IL60344A patent/IL60344A0/xx unknown
-
1981
- 1981-10-08 IE IE812351A patent/IE45226L/xx not_active IP Right Cessation
-
1982
- 1982-08-04 NO NO822674A patent/NO148811C/no unknown
-
1984
- 1984-12-12 DK DK595284A patent/DK165973C/da not_active IP Right Cessation
-
1985
- 1985-07-09 JP JP60149408A patent/JPS61126059A/ja active Granted
-
1993
- 1993-06-09 LU LU88292C patent/LU88292I2/de unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE20 | Patent expired |
Owner name: SCHERING A.G. Effective date: 19970623 |