BE842458A - Aroylation sans catalyseur de derives d'acides 1-alkylpyrrole-2 acetiques - Google Patents

Aroylation sans catalyseur de derives d'acides 1-alkylpyrrole-2 acetiques

Info

Publication number: BE842458A
Authority: BE; Belgium
Prior art keywords: aroylation; alkylpyrrole; catalyst; acetic acid; acid derivatives
Prior art date: 1975-06-02

Application number

BE167534A

Other languages

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-06-02

Filing date

1976-06-01

Publication date

1976-12-01

1976-06-01 Application filed filed Critical

1976-12-01 Publication of BE842458A publication Critical patent/BE842458A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pyrrole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BE167534A 1975-06-02 1976-06-01 Aroylation sans catalyseur de derives d'acides 1-alkylpyrrole-2 acetiques BE842458A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/583,065 US3998844A (en)	1975-06-02	1975-06-02	Uncatalyzed aroylation of 1-alkylpyrrole-2-acetic acid derivatives

Publications (1)

Publication Number	Publication Date
BE842458A true BE842458A (fr)	1976-12-01

Family

ID=24331553

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE167534A BE842458A (fr)	1975-06-02	1976-06-01	Aroylation sans catalyseur de derives d'acides 1-alkylpyrrole-2 acetiques

Country Status (24)

Country	Link
US (1)	US3998844A (xx)
JP (1)	JPS5919536B2 (xx)
AT (1)	AT358572B (xx)
AU (1)	AU497557B2 (xx)
BE (1)	BE842458A (xx)
CA (1)	CA1066297A (xx)
CH (1)	CH603578A5 (xx)
CS (1)	CS220310B2 (xx)
DE (2)	DE2624557C2 (xx)
DK (1)	DK154976C (xx)
ES (1)	ES448408A1 (xx)
FR (1)	FR2313364A1 (xx)
GB (1)	GB1477998A (xx)
HU (1)	HU172047B (xx)
IL (1)	IL49687A (xx)
IN (1)	IN141746B (xx)
NL (1)	NL7605958A (xx)
NZ (1)	NZ180785A (xx)
PL (1)	PL101700B1 (xx)
PT (1)	PT65161B (xx)
RO (1)	RO69252A (xx)
SE (1)	SE414765B (xx)
YU (1)	YU40648B (xx)
ZA (1)	ZA763191B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4048191A (en) *	1975-06-27	1977-09-13	Mcneil Laboratories, Incorporated	Halo-substituted 1-loweralkyl-5-aroylpyrrole-2-acetic acid compounds
US4207237A (en) *	1977-04-20	1980-06-10	Mcneilab, Inc.	Preparation of pyrrole-2-acetates
US4200645A (en) *	1977-05-10	1980-04-29	Beecham Group Limited	Pyrrole derivatives
US4119639A (en) *	1977-06-27	1978-10-10	Mcneil Laboratories, Incorporated	Preparation of 5-aroylpyrrole-2-acetic acid derivatives
GB1592996A (en) *	1977-10-10	1981-07-15	Rolland Sa A	Acylated pyrrole carboxylic acids and derivatives thereof
JPS5481264A (en) *	1977-12-08	1979-06-28	Sagami Chem Res Center	Preparation of 1-methyl-5-aroylpryrrole-2-acetic acid
SE435278B (sv) *	1977-12-08	1984-09-17	Sagami Chem Res	5-cyano-1-legre(c?711?71-?714)alkyl-pyrrol-2-ettiksyra, framstellning derav och anvendningen som mellanprodukt vid framstellning av terapeutiskt verksamma pyrrolderivat
US4216150A (en) *	1978-10-16	1980-08-05	Mcneil Lab, Inc.	Preparation of pyrrole-2-acetates
US4213905A (en) *	1979-06-25	1980-07-22	Mcneilab, Inc.	Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid salts
US4284562A (en) *	1979-11-27	1981-08-18	Mcneilab, Inc.	Process for preparing pyrrole-2-acetic acids
US4255335A (en) *	1980-04-03	1981-03-10	Mcneilab, Inc.	Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid derivatives
US4299770A (en) *	1980-05-29	1981-11-10	Mallinckrodt, Inc.	Recovery of substituted pyrrole acetate
FI77022C (fi) *	1981-08-10	1989-01-10	Merck & Co Inc	Foerfarande foer framstaellning av nya terapeutiskt anvaendbara pyrrolaettiksyraderivat.
US5418236A (en) *	1993-12-23	1995-05-23	Ortho Pharmaceutical Corporation	Anxiolytic aroyl piperidinyl and piperazinylacyl pyrroles
WO2001028997A2 (en)	1999-10-21	2001-04-26	Emory University	Synthesis of 4-substituted pyrrole-2-carbaldehyde compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3752826A (en) *	1970-01-26	1973-08-14	Mcneilab Inc	Aroyl substituted pyrroles
US3846447A (en) *	1972-08-03	1974-11-05	Mcneilab Inc	Preparation of 5-aroyl-pyrroles and intermediates therefor

1975
- 1975-06-02 US US05/583,065 patent/US3998844A/en not_active Expired - Lifetime
1976
- 1976-05-05 IN IN783/CAL/76A patent/IN141746B/en unknown
- 1976-05-05 NZ NZ180785A patent/NZ180785A/xx unknown
- 1976-05-10 GB GB1907276A patent/GB1477998A/en not_active Expired
- 1976-05-14 FR FR7614686A patent/FR2313364A1/fr active Granted
- 1976-05-28 AU AU14405/76A patent/AU497557B2/en not_active Expired
- 1976-05-31 CA CA253,677A patent/CA1066297A/en not_active Expired
- 1976-05-31 IL IL49687A patent/IL49687A/xx unknown
- 1976-05-31 PT PT65161A patent/PT65161B/pt unknown
- 1976-05-31 ES ES448408A patent/ES448408A1/es not_active Expired
- 1976-05-31 JP JP51062478A patent/JPS5919536B2/ja not_active Expired
- 1976-05-31 RO RO7686309A patent/RO69252A/ro unknown
- 1976-06-01 BE BE167534A patent/BE842458A/xx not_active IP Right Cessation
- 1976-06-01 DE DE2624557A patent/DE2624557C2/de not_active Expired
- 1976-06-01 CH CH689476A patent/CH603578A5/xx not_active IP Right Cessation
- 1976-06-01 AT AT401476A patent/AT358572B/de not_active IP Right Cessation
- 1976-06-01 ZA ZA00763191A patent/ZA763191B/xx unknown
- 1976-06-01 SE SE7606165A patent/SE414765B/xx unknown
- 1976-06-01 DE DE19762624558 patent/DE2624558A1/de not_active Withdrawn
- 1976-06-02 PL PL1976190059A patent/PL101700B1/pl unknown
- 1976-06-02 YU YU1360/76A patent/YU40648B/xx unknown
- 1976-06-02 NL NL7605958A patent/NL7605958A/xx not_active Application Discontinuation
- 1976-06-02 CS CS763662A patent/CS220310B2/cs unknown
- 1976-06-02 HU HU76ME00001986A patent/HU172047B/hu unknown
- 1976-06-02 DK DK243676A patent/DK154976C/da active

Also Published As

Publication number	Publication date
DE2624557A1 (de)	1976-12-23
NL7605958A (nl)	1976-12-06
AU497557B2 (en)	1978-12-14
ES448408A1 (es)	1977-11-16
SE7606165L (sv)	1976-12-03
ZA763191B (en)	1978-01-25
ATA401476A (de)	1980-02-15
HU172047B (hu)	1978-05-28
YU136076A (en)	1982-05-31
DE2624558A1 (de)	1976-12-23
CA1066297A (en)	1979-11-13
DK154976B (da)	1989-01-16
CH603578A5 (xx)	1978-08-31
IL49687A (en)	1978-10-31
CS220310B2 (en)	1983-03-25
AU1440576A (en)	1977-12-01
AT358572B (de)	1980-09-25
FR2313364A1 (fr)	1976-12-31
PL101700B1 (pl)	1979-01-31
DK243676A (da)	1976-12-03
DE2624557C2 (de)	1984-04-05
US3998844A (en)	1976-12-27
PT65161B (en)	1978-07-03
SE414765B (sv)	1980-08-18
PT65161A (en)	1976-06-01
DK154976C (da)	1989-06-05
YU40648B (en)	1986-04-30
FR2313364B1 (xx)	1980-09-12
JPS5919536B2 (ja)	1984-05-07
RO69252A (ro)	1981-08-30
IL49687A0 (en)	1976-07-30
GB1477998A (en)	1977-06-29
JPS51143664A (en)	1976-12-10
NZ180785A (en)	1978-03-06
IN141746B (xx)	1977-04-09

Publication	Publication Date	Title
BE848712A (fr)	1977-05-24	Compositions d'acides carboxyliques,
BE851306A (fr)	1977-08-10	Nouveaux derives de l'acide 3-quinoleine carboxylique
BE827794A (fr)	1975-10-10	Derives d'acides phenoxy-alcanoiques
BE842458A (fr)	1976-12-01	Aroylation sans catalyseur de derives d'acides 1-alkylpyrrole-2 acetiques
BE857519A (fr)	1978-02-06	Nouveaux derives d'acides azolyl-carboxyliques
BE847044A (fr)	1977-04-07	Derives de l'acide clavulanique,
BE853574A (fr)	1977-10-14	Nouveaux derives d'acides m-phenyl-phenoxy-propioniques
FR2321276A1 (fr)	1977-03-18	Derives d'acides phenoxy-alkylcarboxyliques
FR2329282A1 (fr)	1977-05-27	Nouveaux derives 4-amines d'acides et d'esters pyrazolo-(1,5-a)quinoxaline-3-carboxyliques
FR2298328A1 (fr)	1976-08-20	Nouveaux derives d'imidazole
FR2348919A1 (fr)	1977-11-18	Derives d'acides phenylacetiques
BE816049A (fr)	1974-09-30	Derives d'acides benzodioxole-1
BE856975A (fr)	1978-01-20	Nouveaux derives d'acides phenoxyphenoxy-alcanecarboxyliques
FR2321294A1 (fr)	1977-03-18	Derives d'acides 7b-amino-3-cephem-3-carbonylmethyl-4-carboxyliques utiles comme medicaments
BE830781A (fr)	1975-12-29	Preparation d'acides carboxyliques, plus particulierement preparation d'alpha-ceto-acides
FR2321488A1 (fr)	1977-03-18	Derives d'acides aminoalcane sulfoniques, leur obtention et leur application
BE817112A (fr)	1974-11-04	Nouveaux derives d'acides cycloalkyl-phenoxy-carboxyliques
BE841165A (fr)	1976-10-27	Derives d'acides 8-aza-prostanoiques et leur procede de preparation
FR2316931A1 (fr)	1977-02-04	Derives d'acides dl- et 8 r-9-fluoro-prostadienoiques
BE849726A (fr)	1977-06-22	Alpha-nonoacetals de derives d'acides alpha, beta-dioxo-carboxyliques, utililsables comme inducteurs de photopolymerisation
BE847046A (fr)	1977-04-07	Derives de l'acide clavulanique,
BE837561A (fr)	1976-07-14	Preparation d'acides 6,11-dihydro-11-oxodibenzo (b,e) oxepine alcanoiques
BE846657A (fr)	1977-01-17	2,4,6-triiodo-anilides 3,5-disubstitues d'acides polyhydroxy-monobasiques
FR2314914A1 (fr)	1977-01-14	Preparation d'acides aromatiques
BE882360A (fr)	1980-09-22	Derives d'acides 3-heterocyclo-thiomethyl-7alpha-methoxy-7beta-acylamino-3-cephem-4-carboxyliques insatures

Legal Events

Date	Code	Title	Description
1993-06-25	CCPA	Application for a supplementary protection certificate	Free format text: 093C0116
1996-01-01	RE20	Patent expired	Owner name: MCNEIL LABORATORIES INC. Effective date: 19960601

Date

Code

Title

Description

1993-06-25

CCPA

Application for a supplementary protection certificate

Free format text: 093C0116

1996-01-01

RE20

Patent expired

Owner name: MCNEIL LABORATORIES INC.

Effective date: 19960601