BE1002266A5 - Compositions de cyclosporine pour application topique. - Google Patents
Compositions de cyclosporine pour application topique. Download PDFInfo
- Publication number
- BE1002266A5 BE1002266A5 BE8900520A BE8900520A BE1002266A5 BE 1002266 A5 BE1002266 A5 BE 1002266A5 BE 8900520 A BE8900520 A BE 8900520A BE 8900520 A BE8900520 A BE 8900520A BE 1002266 A5 BE1002266 A5 BE 1002266A5
- Authority
- BE
- Belgium
- Prior art keywords
- topical application
- compositions
- cyclosporin compositions
- alcohol
- cyclosporin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention a pour objet des compositions pharmaceutiques comprenant une cyclosporine, par exemple la Ciclosporine, et un acide ou un alcool gras mono- ou polyinsaturé, par exemple l'acide oléique ou l'alcool oléylique. Les compositions conviennent pour une application dermique, par exemple dans le traitement d'une maladie auto-immune de la peau pour favoriser la pousse des cheveux.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888811357A GB8811357D0 (en) | 1988-05-13 | 1988-05-13 | Improvements in/relating to organic compounds |
GB888824779A GB8824779D0 (en) | 1988-10-21 | 1988-10-21 | Improvements in/relating to organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
BE1002266A5 true BE1002266A5 (fr) | 1990-11-13 |
Family
ID=26293884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE8900520A BE1002266A5 (fr) | 1988-05-13 | 1989-05-12 | Compositions de cyclosporine pour application topique. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5807820A (fr) |
JP (1) | JPH075473B2 (fr) |
BE (1) | BE1002266A5 (fr) |
CH (1) | CH679119A5 (fr) |
DE (2) | DE3943838B4 (fr) |
FR (1) | FR2631235B1 (fr) |
GB (1) | GB2218334B (fr) |
IT (1) | IT1232832B (fr) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0148748B1 (ko) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
US5540931A (en) * | 1989-03-03 | 1996-07-30 | Charles W. Hewitt | Methods for inducing site-specific immunosuppression and compositions of site specific immunosuppressants |
US4996193A (en) * | 1989-03-03 | 1991-02-26 | The Regents Of The University Of California | Combined topical and systemic method of administration of cyclosporine |
ES2087165T3 (es) * | 1989-11-30 | 1996-07-16 | Croda Int Plc | Uso de acido nervonico y de acidos grasos de cadenas largas en el tratamiento de las alteraciones provocadas por la desmielinizacion. |
WO1992011036A1 (fr) * | 1990-12-21 | 1992-07-09 | Wade, Jonathan, Leslie | Adjuvants comprenant des lipides insatures |
GB9105705D0 (en) * | 1991-03-18 | 1991-05-01 | Sandoz Ltd | Improvements in or relating to organic compounds |
GB9113872D0 (en) * | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
IL102236A0 (en) * | 1991-06-27 | 1993-01-14 | Ltt Inst Co Ltd | Topical preparations containing cyclosporin |
US6262022B1 (en) | 1992-06-25 | 2001-07-17 | Novartis Ag | Pharmaceutical compositions containing cyclosporin as the active agent |
AU688920B2 (en) * | 1991-06-27 | 1998-03-19 | Novartis Ag | Transesterified corn oil products |
US5378152A (en) * | 1992-05-01 | 1995-01-03 | Dental Marketing Specialists, Inc. | Method and apparatus for installation of dental implant |
EP0642332B1 (fr) | 1992-05-13 | 1997-01-15 | Sandoz Ltd. | Compositions ophtalmiques contenant une cyclosporine |
EP1142568A1 (fr) | 1992-09-25 | 2001-10-10 | Novartis AG | Compositions pharmaceutiques à base de cyclosporines |
NZ247516A (en) * | 1993-04-28 | 1995-02-24 | Bernard Charles Sherman | Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant |
JP2727053B2 (ja) * | 1993-12-27 | 1998-03-11 | 東亜機工 株式会社 | パンティライナーおよびその製造装置 |
EP0743846B1 (fr) * | 1994-02-02 | 2000-10-04 | The Procter & Gamble Company | Compositions de soins pour les cheveux contenant un alcool gras a point de fusion peu eleve et un polymere d'oxyde d'ethylene/oxyde de propylene |
RU2158601C2 (ru) | 1994-11-03 | 2000-11-10 | Новартис Аг | Новые лекарственные формы циклоспорина для орального применения с простым составом и высокой биодоступностью и способ их получения |
DE19549852B4 (de) | 1995-11-29 | 2009-06-04 | Novartis Ag | Cyclosporin enthaltende Präparate |
US5858401A (en) | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
DE19611953A1 (de) * | 1996-03-26 | 1997-10-02 | Beiersdorf Ag | Verwendung von ungesättigten Monocarbonsäuren gegen Superinfektionen |
CZ267796A3 (cs) * | 1996-09-12 | 1998-04-15 | Galena A.S. | Léčivé přípravky, zejména pro vnitřní aplikaci, ve formě samomikroemulgujících terapeutických systémů |
NZ314060A (en) * | 1997-01-13 | 1997-08-22 | Bernard Charles Sherman | Pharmaceutical microemulsion preconcentrate comprising cyclosporin dissolved in a solvent system comprising hydrophobic solvent(s) and surfactant(s) |
BR9807528A (pt) | 1997-01-30 | 2000-03-14 | Novartis Ag | Composições farmacêuticas isentas de óleo contendo ciclosporina a |
TW592719B (en) * | 1997-03-26 | 2004-06-21 | Shiseido Co Ltd | Hair growth phase extender composition containing unsaturated fatty acid and/or its derivatives or an extract of a plant belonging to the Coriandrum |
EP0888773A1 (fr) * | 1997-07-05 | 1999-01-07 | Societe Des Produits Nestle S.A. | Utilisation de l'acide pétrosélinique pour le traitement des inflammations des tissus superficiels |
US6346511B1 (en) | 1997-09-08 | 2002-02-12 | Panacea Biotec Limited | Pharmaceutical composition comprising cyclosporin |
US6008191A (en) * | 1997-09-08 | 1999-12-28 | Panacea Biotec Limited | Pharmaceutical compositions containing cyclosporin |
US6187747B1 (en) | 1997-09-08 | 2001-02-13 | Panacea Biotech Limited | Pharmaceutical composition comprising cyclosporin |
US6042841A (en) * | 1998-03-16 | 2000-03-28 | Unilever Home & Personal Care Usa Division Of Conopco, Inc. | Cosmetic method of treating skin |
US6022896A (en) * | 1998-09-10 | 2000-02-08 | Chesebrough-Pond's Usa Co. | Petroselinic acid as an anti-irritant in compositions containing alpha-hydroxy acids |
FR2782638B1 (fr) * | 1998-08-28 | 2003-04-11 | Shiseido Internat France S A S | Utilisation en cosmetique d'acides gras |
US6288112B1 (en) | 1998-11-20 | 2001-09-11 | The General Hospital Corporation | Use of pyrethroid compounds to promote hair growth |
US6638522B1 (en) | 1998-12-11 | 2003-10-28 | Pharmasolutions, Inc. | Microemulsion concentrate composition of cyclosporin |
PT1091750E (pt) | 1999-02-26 | 2009-11-10 | Maas Biolab Llc | Composição farmacêutica cerebroespinal e vascular e processo para a sua preparação |
AU3861900A (en) * | 1999-03-05 | 2000-09-21 | University Of Texas Southwestern Medical Center, The | Method of treating hair loss using non-immunosuppressive compounds |
US6057289A (en) * | 1999-04-30 | 2000-05-02 | Pharmasolutions, Inc. | Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system |
US6680344B1 (en) | 1999-06-01 | 2004-01-20 | The University Of Texas Southwestern Medical Center | Method of treating hair loss using diphenylmethane derivatives |
US6723717B1 (en) | 1999-06-01 | 2004-04-20 | The University Of Texas Southwestern Medical Center | Sulfur-containing thyroxane derivatives and their use as hair growth promotors |
AU3712100A (en) | 1999-06-01 | 2000-12-18 | University Of Texas Southwestern Medical Center, The | Method of treating hair loss using sulfonyl thyromimetic compounds |
US6521595B1 (en) * | 1999-11-19 | 2003-02-18 | Lg Chemical, Ltd. | Nonimmunosuppressive [γ-hydroxy-methylleucine4] cyclosporin A, hair growth stimulator and external composition for skin using the same |
AU1420801A (en) * | 1999-11-19 | 2001-05-30 | Lg Household & Health Care Ltd. | Use of nonimmunosuppressive cyclosporin derivatives for hair growth |
DE10053328A1 (de) * | 2000-10-27 | 2002-05-08 | Cognis Deutschland Gmbh | Kosmetische Zubereitungen |
KR100360716B1 (ko) * | 2000-11-22 | 2002-11-13 | 주식회사 엘지생활건강 | 사이클로스포린 에이 7- 티오아미드 유도체를유효성분으로 하는 모발성장촉진제 |
KR20020039528A (ko) * | 2000-11-22 | 2002-05-27 | 조명재 | 사이클로스포린 7- 티오아미드 유도체를 유효성분으로하는 모발성장촉진제 |
KR20020050135A (ko) * | 2000-12-20 | 2002-06-26 | 조명재 | 피부 주름 예방 및 완화를 목적으로 하는 피부 외용 조성물 |
KR100681670B1 (ko) * | 2001-02-14 | 2007-02-09 | 주식회사 엘지생활건강 | [감마 히드록시 엔- 메틸-엘-루신9]사이클로스포린 에이를유효성분으로 하는 모발 성장 촉진제 |
IL142535A0 (en) * | 2001-04-11 | 2002-03-10 | Yeda Res & Dev | Pharmaceutical compositions for the treatment of inflammation |
KR100465012B1 (ko) * | 2001-05-11 | 2005-01-13 | 주식회사 엘지생활건강 | 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제 |
KR100695610B1 (ko) * | 2001-05-15 | 2007-03-14 | 주식회사 엘지생활건강 | 비면역성 발모성분인 [감마 히드록시 엔-메틸 엘-루신4] 사이클로스포린 유도체를 함유한 두피 및 경피용 제제 조성물 |
KR100695611B1 (ko) * | 2001-05-17 | 2007-03-14 | 주식회사 엘지생활건강 | [감마 히드록시 엔-메틸 엘-루신4] 사이클로스포린유도체를 유효성분으로 하는 모발 성장 촉진제 |
AU2002231703B2 (en) | 2001-12-14 | 2007-03-29 | Jagotec Ag | Pharmaceutical formulation comprising cyclosporin and use thereof |
US6987090B2 (en) | 2002-05-09 | 2006-01-17 | Lg Household & Health Care Ltd. | Use of 3-position cyclosporin derivatives for hair growth |
ZA200502613B (en) * | 2002-10-10 | 2006-10-25 | Yeda Res & Dev | Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents |
KR100439467B1 (ko) * | 2002-11-13 | 2004-07-09 | 주식회사 엘지생활건강 | 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제 |
WO2004071398A2 (fr) * | 2003-02-17 | 2004-08-26 | Cipla Ltd | Composition pharmaceutique |
US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
GB0413730D0 (en) * | 2004-06-18 | 2004-07-21 | Tillotts Pharma Ag | A pharmaceutical composition and its use |
GB0413729D0 (en) * | 2004-06-18 | 2004-07-21 | Tillotts Pharma Ag | A pharmaceutical composition and its use |
US7135455B2 (en) * | 2004-11-15 | 2006-11-14 | Allergan, Inc | Methods for the therapeutic use of cyclosporine components |
US7151085B2 (en) * | 2004-11-15 | 2006-12-19 | Allergan, Inc. | Therapeutic methods using cyclosporine components |
IL181217A0 (en) * | 2007-02-08 | 2007-07-04 | Haim Levy | Pharmaceuticalcompositions based on a microemulsion |
WO2008106091A1 (fr) * | 2007-02-26 | 2008-09-04 | Yeda Research And Development Co. Ltd. | Utilisation de dérivés d'alcool à longue chaîne pour le traitement de l'alopécie aerata |
WO2008106092A1 (fr) * | 2007-02-26 | 2008-09-04 | Yeda Research And Development Co. Ltd. | Énantiomères d'ester octadéc-9-(z)énylique d'acide amino-phényl-acétique, leurs sels et leurs utilisations |
CA2697756A1 (fr) * | 2007-09-10 | 2009-03-19 | Maruho Co., Ltd. | Composition pharmaceutique de type emulsion de cristaux liquides contenant de la cyclosporine et procede de traitement d'une maladie de la peau par celle-ci |
TW200932240A (en) * | 2007-10-25 | 2009-08-01 | Astellas Pharma Inc | Pharmaceutical composition containing lipophilic substance which inhibits IL-2 production |
WO2021134028A1 (fr) * | 2019-12-24 | 2021-07-01 | Ampersand Biopharmaceuticals, Inc. | Cyclosporine topique pour le traitement du psoriasis et d'autres maladies |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0127426A1 (fr) * | 1983-05-23 | 1984-12-05 | Takeda Chemical Industries, Ltd. | Compositions pharmaceutiques percutanées pour application externe |
EP0171742A2 (fr) * | 1984-08-10 | 1986-02-19 | E.I. Du Pont De Nemours And Company | Administration transdermale de dérivés opiacés |
WO1987006463A1 (fr) * | 1986-05-02 | 1987-11-05 | Brigham And Women's Hospital | Composition a faible nephrotoxicite comprenant un composant contenant un acide gras et de la cyclocporine |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2528516A1 (de) * | 1974-07-05 | 1976-01-22 | Sandoz Ag | Neue galenische zubereitung |
FI65914C (fi) * | 1978-03-07 | 1984-08-10 | Sandoz Ag | Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a |
CA1165240A (fr) * | 1980-07-09 | 1984-04-10 | The Procter & Gamble Company | Composes pharmaceutiques a usage topique |
US4590190A (en) * | 1983-07-01 | 1986-05-20 | Nitto Electric Industrial Co., Ltd. | Method for percutaneously administering physiologically active agents using an alcohol adjuvant and a solvent |
JPS6097544A (ja) * | 1983-11-01 | 1985-05-31 | Casio Comput Co Ltd | 薄型電池 |
CH667274A5 (de) * | 1984-03-23 | 1988-09-30 | Sandoz Ag | Cyclosporine, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen. |
US4649047A (en) * | 1985-03-19 | 1987-03-10 | University Of Georgia Research Foundation, Inc. | Ophthalmic treatment by topical administration of cyclosporin |
JPS61280435A (ja) * | 1985-04-04 | 1986-12-11 | Kanji Takada | サイクロスポリン類のリンパ指向性製剤 |
JPS61249918A (ja) * | 1985-04-26 | 1986-11-07 | Yutaka Mizushima | 点眼剤 |
DE3531597A1 (de) * | 1985-09-04 | 1987-03-05 | Bioferon Biochem Substanz | Verwendung von interferon-gamma (ifn-gamma) enthaltenden praeparationen zur behandlung psoriatischer erkrankungen |
ZA875317B (en) * | 1986-08-01 | 1988-01-25 | Warner-Lambert Company | Transdermal compositions |
MY102980A (en) * | 1986-10-31 | 1993-03-31 | Pfizer | Transdermal flux enhancing compositions |
US4798823A (en) * | 1987-06-03 | 1989-01-17 | Merck & Co., Inc. | New cyclosporin analogs with modified "C-9 amino acids" |
GB2206119B (en) * | 1987-06-22 | 1990-10-31 | Merck & Co Inc | A new cyclosporin derivative with modified "8-amino acid" |
GB8717300D0 (en) * | 1987-07-22 | 1987-08-26 | Nat Res Dev | Cyclosporins |
US4839342A (en) * | 1987-09-03 | 1989-06-13 | University Of Georgia Research Foundation, Inc. | Method of increasing tear production by topical administration of cyclosporin |
US4970016A (en) * | 1987-09-29 | 1990-11-13 | Colgate-Palmolive Co. | Thixotropic aqueous liquid automatic dishwashing detergent composition |
GB8729153D0 (en) * | 1987-12-14 | 1988-01-27 | Efamol Ltd | Fatty acid compositions |
GB8823621D0 (en) * | 1988-10-07 | 1988-11-16 | Madhok R | Compositions containing cyclosporins |
-
1989
- 1989-05-09 CH CH1735/89A patent/CH679119A5/de not_active IP Right Cessation
- 1989-05-10 GB GB8910707A patent/GB2218334B/en not_active Expired - Lifetime
- 1989-05-12 JP JP1120234A patent/JPH075473B2/ja not_active Expired - Lifetime
- 1989-05-12 IT IT8947949A patent/IT1232832B/it active
- 1989-05-12 FR FR8906463A patent/FR2631235B1/fr not_active Expired - Lifetime
- 1989-05-12 DE DE3943838A patent/DE3943838B4/de not_active Expired - Lifetime
- 1989-05-12 BE BE8900520A patent/BE1002266A5/fr not_active IP Right Cessation
- 1989-05-12 DE DE3915617A patent/DE3915617B4/de not_active Expired - Lifetime
-
1995
- 1995-05-22 US US08/446,984 patent/US5807820A/en not_active Expired - Lifetime
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0127426A1 (fr) * | 1983-05-23 | 1984-12-05 | Takeda Chemical Industries, Ltd. | Compositions pharmaceutiques percutanées pour application externe |
EP0171742A2 (fr) * | 1984-08-10 | 1986-02-19 | E.I. Du Pont De Nemours And Company | Administration transdermale de dérivés opiacés |
WO1987006463A1 (fr) * | 1986-05-02 | 1987-11-05 | Brigham And Women's Hospital | Composition a faible nephrotoxicite comprenant un composant contenant un acide gras et de la cyclocporine |
Also Published As
Publication number | Publication date |
---|---|
DE3943838B4 (de) | 2009-06-25 |
GB2218334A (en) | 1989-11-15 |
GB2218334B (en) | 1991-10-02 |
JPH075473B2 (ja) | 1995-01-25 |
JPH0217127A (ja) | 1990-01-22 |
DE3915617A1 (de) | 1989-11-16 |
CH679119A5 (fr) | 1991-12-31 |
US5807820A (en) | 1998-09-15 |
DE3915617B4 (de) | 2007-01-18 |
IT8947949A0 (it) | 1989-05-12 |
FR2631235A1 (fr) | 1989-11-17 |
IT1232832B (it) | 1992-03-05 |
FR2631235B1 (fr) | 1994-04-29 |
GB8910707D0 (en) | 1989-06-28 |
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Date | Code | Title | Description |
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RE20 | Patent expired |
Owner name: *NOVARTIS A.G. Effective date: 20090512 |