AU752966B2

AU752966B2 - Agrochemical emulsifiable concentrates

Info

Publication number: AU752966B2
Application number: AU20099/99A
Authority: AU
Inventors: Stanley J Kostka; Rennan Pan
Original assignee: Aquatrols Holding Co Inc
Current assignee: Aquatrols Holding Co Inc
Priority date: 1997-12-30
Filing date: 1998-12-23
Publication date: 2002-10-03
Anticipated expiration: 2018-12-23
Also published as: WO1999033340A1; CA2317542A1; CA2317542C; AU2009999A; EP1043927A1

Description

WO 99/33340 PCT/US98/27358 AGROCHEMICAL EMULSIFIABLE CONCENTRATES 1. Field of the Invention The instant invention relates to highly concentrated, low volatile organic compound (low VOC) aqueous agrochemical compositions and methods for preparing same. The invention also relates to bioefficaciously enhanced organophosphorous insecticidal formulations comprising said active and low volatile organic compound (low VOC) compositions; processes for preparing same; and methods of use.

2. Technology Description When agrochemical actives are relatively water soluble, preparing, storing, and shipping same in a commercially acceptable form can be a relatively simple matter.

However, many, if not most, agrochemical actives are not very water soluble and formulators are constantly using their ingenuity to find means for preparing these materials in stable formulations that deliver maximum loading of active ingredient per unit volume to the end-user. One means of doing this is to prepare dry formulations such as wettable dispersible granules (WDG's) or wettable powders (WP's) encapsulated, for example, in water soluble bags or containers. Although such dry formulations are attractive not only from a loading delivery viewpoint, but also from a handling and/or worker safety viewpoint, not all water-insoluble agrochemicals are able to be dry formulated.

Insecticides, miticides, aphicides, fungicides, bacteriocides, acaricides, nematicides (hereinafter these pesticides will be generically referred to for conciseness as "insecticides" as the term "insecticidally" will similarly represent generically miticidally, nematicidally, etc.) continue to be a group of products of immense agricultural and WO 99/33340 PCT/US98/27358 economic importance. Insecticides are expected to display ideal properties of a wide array including broad-spectrum activity concomitant with safety to beneficial insects, low mammalian and fish toxicity, and sufficiently long residual action yet with insignificant, harmless residue levels. In keeping with the above goals, it is desirable to utilize the minimum amount of insecticide necessary to achieve the required results. Therefore, formulation adjuvants that enhance the bioefficacy of the active and thus result in lower effective delivery amounts of the active to a locus are much sought after.

Many insecticidal compounds, like most agrochemical actives, are solid materials which have very low solubility in water. As a result, preparing these materials in stable formulations with maximum loading of active ingredient per unit volume to the end-user presents a constant challenge to agrochemical formulators.

One of the most common ways to formulate insecticidal compounds is as emulsifiable concentrates (ECs). When added to water, ECs produce oil-in-water emulsions either spontaneously or by gentle agitation. Despite the evolution of other upto-date formulations, ECs are still widely used worldwide because of their simple manufacturing process and low cost.

The most straight-forward approach to preparing concentrated liquid formulations with agrochemical actives, especially insecticides having limited aqueous solubility, has been through the use of aromatic organic solvent systems. In such systems, aromatic organic solvents such as xylene or kerosene are used to solubilize the pesticidal compound of interest.

Commonly, surfactants are also added to the insecticide-solvent compositions to form emulsifiable concentrates. The surfactant-emulsifiers interact with the insecticides WO 99/33340 PCT/US98/27358 in a number of ways both before and during actual use, application to the locus. The surfactants, often a pair of nonionic and anionic surfactants, can initially disperse and/or emulsify the insecticide in the solvent or in an inert carrier media and may also act as spreader, sticker, stabilizer, wetting agent, and defoamer. The surfactant composition may affect the rate of drying of a droplet on a surface and the nature of a residue liquid or crystal.

The presence of the volatile organic compounds in these formulations, together with the surfactants, enable stable emulsifiable insecticidal concentrates (EC's) to be prepared. Although such EC formulations have played and continue to play a major role in the insecticidal market, they have a significant drawback in that the formulations are commonly based on the use of considerable quantities of highly volatile organic compounds (high VOC's). These high VOC's create both toxicological and ecotoxicological problems. As a result, many government agencies such as the United States Environmental Protection Agency and the European Economic Community Council are proposing legislation and many countries such as Germany and Canada are now requiring eco-labeling of formulations which contain high VOC's.

Thus, to reduce not only the deleterious effects upon the environment, but also the potential for hazardous worker exposure situations, especially in closed environments such as greenhouses, agricultural/chemical manufacturers and formulators continually seek ways to deliver highly loaded, stable insecticidal formulations to the end-user with significantly reduced levels of high VOC's and preferably without their presence.

To avoid the use of high VOC's in certain pesticidal formulations and to obtain slightly increased pesticidal loadings, Lubetzky, et al. in EP publication numbers 669,078 3 WO 99/33340 PCT/US98/27358 and 670,113 have disclosed the use of rosin and rosin derivatives that are insoluble in water to "plasticize" certain pesticides and thus to prepare pesticidal emulsions in water (EW's) and emulsifiable concentrates (EC's).

Applicants have discovered extremely stable, highly loaded water soluble, low VOC pesticidal emulsion concentrates comprising a) a pesticide having a melting point of 120 0 C or less, preferably 1100 C or less; b) an alkoxylated fatty acid and rosin acid composition having from greater than 25 to about 60 weight percent alkoxylated rosin acids and from about 40 to less than 75 weight percent alkoxylated fatty acids with about 9 to 20 alkoxy moieties per molecule of acid; and c) at least one nonionic surfactant.

Furthermore, it has been discovered that the aforedescribed alkoxylated acid compositions possess very unique solvent characteristics with respect to certain relatively water insoluble pesticides.

Summary of the Invention This invention relates to stable, low VOC pesticidal emulsifiable concentrates comprising a) a pesticide having a melting point of 120 0 C or less, preferably 1100 C or less; b) a solvent for said pesticide comprising an alkoxylated fatty acid and rosin acid composition having from greater than about 25 to about 60 weight percent alkoxylated rosin acids and from about 40 to less than about 75 weight percent alkoxylated fatty acids the weight percents of the fatty acids and rosin acids being based on the total weight of the alkoxylated acid composition wherein the alkoxylated composition contains an average molar addition of from about 9 to 20 alkoxy moieties per molecule of acid; and c) at least one nonionic surfactant.

The instant invention also relates to the discovery that said alkoxylated fatty/rosin acid formulations not only provide extremely stable, highly loaded solvent systems, but that these formulations also significantly enhance the bioefficacy of specific organophosphorous insecticidal compounds.

Accordingly, in a first embodiment of the invention there is provided an agrochemical emulsifiable concentrate comprising: a) from about 10 to about 60 percent by weight of a water-insoluble pesticide having a melting point of less than about 1200C; b) from about 20 to about 60 percent by weight of an alkoxylated acid o0 composition wherein said acid composition comprises: i) from greater than about 25 to about 60 percent by weight alkoxylated rosin acids; and S..a.i ii) from about 40 to less than about 75 percent by weight alkoxylated fatty acids wherein the rosin acids and fatty acids have an average molar addition of from 15 about 6 to about 20 alkoxy moieties per molecule of acid; the weight percents of the rosin and fatty acids being based on the total weight of said alkoxylated acids; and c) from about 15 to about 45 percent by weight of nonionic surfactant; wherein the weight percents are based on the total weight of the emulsifiable concentrate except where indicated.

20 According to a second embodiment of the invention there is provided an organophosphorous insecticidal emulsifiable concentrate comprising: a) from about 10 to about 60 percent by weight of an organophosphorous insecticide having a melting point of less than about 1200C; b) from about 20 to about 60 percent by weight of an alkoxylated acid 25 composition wherein said acid composition comprises: i) from greater than about 25 to about 60 percent by weight alkoxylated rosin acids; and ii) from about 40 to less than about 75 percent by weight alkoxylated fatty acids wherein the rosin acids and fatty acids have an average molar addition of from about 6 to about 20 alkoxy moieties per molecule of acid; the weight percents of the rosin and fatty acids being based on the total weight of said alkoxylated acids; and c) from about 15 to about 45 percent by weight of nonionic surfactant; wherein the weight percents are based on the total weight of the emulsifiable concentrate except where indicated.

[I:\DayLib\LIBZZ]05003.doc:mrr I I According to a third embodiment of the invention there is provided a method of preparing agrochemical emulsifiable concentrates comprising the steps of: i) blending a) from about 10 to about 60 percent by weight of a water-insoluble s pesticide having a melting point of less than about 120 0

C;

b) from about 20 to about 60 percent by weight of an alkoxylated acid composition wherein said acid composition comprises: i) from greater than about 25 to about 60 percent by weight alkoxylated rosin acids; and to ii) from about 40 to less than about 75 percent by weight alkoxylated fatty acids wherein the rosin acids and fatty acids have an average molar addition of from about 6 to about 20 alkoxy moieties per molecule of acid; the weight percents of the rosin and fatty acids being based on the total weight of said alkoxylated acids; and c) from about 15 to about 45 percent by weight of nonionic surfactant; 15 wherein the weight percents are based on the total weight of the emulsifiable concentrate except where indicated; ii) heating said nonionic surfactant to above the melting point either prior to, during, or after the blending; and iii) cooling the emulsion concentrate so formed to ambient temperature.

20 According to a fourth embodiment of the invention there is provided an agrochemical emulsifiable concentrate prepared according to the third embodiment.

According to a fifth embodiment of the invention there is provided a method of *o preparing organophosphorous insecticidal emulsifiable concentrates comprising the steps of: 25 i) blending a) from about 10 to about 60 percent by weight of an organophosphorous insecticide having a melting point of less than about 120 0

C;

b) from about 20-to-about60 percen by weight of an alkoxylated acit composition wherein said acid composition comprises: i) from greater than about 25 to about 60 percent by weight alkoxylated rosin acids; and ii) from about 40 to less than about 75 percent by weight alkoxylated fatty acids wherein the rosin acids and fatty acids have an average molar addition of from /out 6 to about 20 alkoxy moieties per molecule of acid; the weight percents of the rosin a fatty acids being based on the total weight of said alkoxylated acids; and [I:\DayLib\LIBZZ]05003.doc:mff c) from about 15 to about 45 percent by weight of nonionic surfactant; wherein the weight percents are based on the total weight of the emulsifiable concentrate except where indicated; ii) heating said nonionic surfactant to above the melting point either prior to, during, or after the blending; and iii) cooling the emulsifiable concentrate so formed to ambient temperature.

According to a sixth embodiment of the invention there is provided a method of preparing organophosphorous insecticidal emulsion concentrates consisting essentially of the steps of: i) melting from about 10 to about 60 percent by weight of an organophosphorous insecticide having a melting point of less than about 120 0

C;

ii) blending the molten insecticide with from about 20 to about 60 percent by weight of a water-soluble alkoxylated acid composition wherein said acid composition o comprises: 1 5 a) from greater than about 25 to about 60 percent by weight alkoxylated rosin acids; and b) from about 40 to less than about 75 percent by weight alkoxylated fatty acids wherein the rosin acids and fatty acids have an average molar addition of from about 6 to about 20 alkoxy moieties per molecule of acid; the weight percents of the rosin and fatty acids being based on the total weight of said alkoxylated acids; and iii) from about 15 to about 45 percent by weight of nonionic surfactants other than said alkoxylated rosin and alokoxylated fatty acids wherein said concentrate is essentially free of volatile organic compounds; and wherein the weight percents are based on the total weight of the emulsion concentrate except wherein indicated.

25 According to a seventh embodiment of the invention there is provided an organophosphorous insecticidal emulsifiable concentrate prepared according to the fifth or sixth embodiment.

According to an eighth embodiment of the invention there is provided a method of controlling insects which comprises subjecting them to an insecticidally effective amount of a composition comprising the emulsifiable concentrate of the second or seventh embodiment.

According to a ninth embodiment of the invention there is provided an organophosphorous insecticidal emulsifiable concentrate according to the second or Sr v venth embodiment when used for controlling insects.

[l:\DayLib\LIBZZ]05003 .doc:mrr According to a tenth embodiment of the invention there is provided use of an organophosphorous insecticidal emulsifiable concentrate according to the second or seventh embodiment in the preparation of a composition for controlling insects.

According to an eleventh embodiment of the invention there is provided an insecticidal composition comprising a concentrate according to the second or seventh embodiment together with at least one diluent or carrier.

According to a twelfth embodiment of the invention there is provided an agrochemical composition comprising a concentrate according to the first or fourth embodiment together with at least one diluent or carrier.

Detailed Description of the Invention It has been discovered that certain water-soluble fatty acid/rosin acid alkoxylated compositions possess very unique solvent characteristics with respect to certain water insoluble pesticides. Specifically, it has been discovered that water insoluble pesticides having low to medium melting points can be melted and readily dissolved in a low VOC 15 water-soluble solvent prepared by highly alkoxylating a mixture of fatty acids and rosin acids; preferably a tall oil mixture.

Additionally, it has been discovered that not only do certain of the water-soluble fatty acid-rosin acid ethoxylate composition possess unique solvent characteristics with respect to low melting organophosphorous insecticidal compounds, but also that these 20 adjuvant compositions significantly enhance the bioefficacy of the organophosphorous active. A preferred method of preparing emulsifiable concentrates of these components is to melt the organophosphorous insecticide and dissolve same in the highly ethoxylated mixture of the fatty acids and rosin acids; preferably a tall oil mixture.

The primary fatty acids useful in the process of this invention are the C 14 to C 20 unsaturated acids, especially the fatty acids selected from the group consisting of oleic, linoleic, conjugated linoleic acids, palmitic, stearic, and mixtures thereof.

The primary rosin acids useful in the process of this invention are the C 1 9

-C

20 aromatic acids, especially the rosin acids selected from the group consisting of abietic, [I:\DayLib\LIBZZ]05003 .doc:mrr WO 99/33340 PCT/US98/27358 neoabietic, dehydroabietic, tetrahydroabietic, palustric, pimaric acids and mixtures thereof.

The final acid compositions, whose components are subsequently alkoxylated either prior to being mixed together to form the composition or after the acid composition mixture is present, comprise from greater than about 25 to about 60 weight percent alkoxylated rosin acids, preferably from 30 to 40 weight percent alkoxylated rosin acid; and from about 40 to less than about 75 weight percent, preferably from about 60 to about weight percent fatty acids; all of the above acid weight percents based on the total weight of the alkoxylated fatty acids and rosin acids composition.

The water-soluble alkoxylated compositions should contain an average molar addition of from about 6 to about 20 alkoxy moieties per molecule of acid; preferably from about 9 to about 16.

As noted above, although the rosin acids can be obtained individually from natural products such as wood and gum resins and the fatty acids can be obtained individually, for example, from natural oils and fats such as olive oil, peanut oil, butter fat, cottonseed, soybean and so on, the fatty acid/rosin acid compositions of this invention are preferably obtained from certain tall oil products.

The pine tree is the source of tall oil which is liberated when wood is converted to paper pulp by the sulfate or Kraft process. During the pulping process, an alkaline digestion liquor ("black liquor") is washed out of the pulp. Rosin soaps and fatty acid soaps are skimmed off of this black liquor and acidification releases free rosin and fatty acids. This mixture was originally called Tallolja (Swedish for pine oil) and the term "tall oil" was eventually adapted as a standard by the United States.

WO 99/33340 PCT/US98/27358 The fatty acids in crude tall oil typically consist mainly of a mixture of oleic acid

[CH

3

(CH

2 7 CH=CH (CH2)7COOH]; linoleic acid [CH 3

(CH

2 4 CH CH

CH

2 CH CH (CH2)7 COOH]; linoleic acid, conjugated (includes higher molecular weight polyunsaturated acids) [CH 3

(CH

2 4 CH, CH CH CH CH (CH2) 7 COOH]; palmitic acid [CH 3

(CH

21 4 COOH]; and stearic acid [CH 3

(CH

2 COOH]. Also present are palmitoleic acid and to a small extent, higher molecular weight saturated acids such as arachidic (C, 2 behinic (C 22 lignoceric (C 24 and cerotic (C 26 acids, C 20 and higher molecular weight unsaturated and polyunsaturated acids, and small amounts of low boiling point monobasic and dibasic acids.

The rosin acids in crude tall oil are similar to those occurring in wood and gum rosin and typically consist mainly of abietic acid [30 40%] in equilibrium with its isomer neoabietic acid [4 palustric acid dehydroabietic acid [5 pimaric acid [8 with dehydroabietic and tetrahydroabietic acids comprising 2 to 28%.

The fatty acid/rosin acid compositions of this invention are alkoxylated, i.e., polyoxyalkylene esters are prepared, by using art-recognized, standard condensation techniques readily available; known to those skilled in the art; and described in numerous publications, for example, on pages 142 to 170 of chapter 5 of the book "Nonionic Surfactants" by W. B. Satkowski, S. K. Huang, and R. L. Liss, edited by M. J. Schick, Lever Bros. Co. Research Center, Edgewater, New Jersey (Marcel Dekker, Inc., New York). Typical procedures are set forth in U.S. Patent Nos. 2,586,767 and 2,610,966.

The organic carboxylic acids may be either directly esterified with alkylene oxide or through a reaction with polyalkylene glycol intermediates. The alkylene oxides which may be used to prepare the nonionic monofunctional polyoxyalkylene esters or WO 99/33340 PCT/US98/27358 polyalkylene glycol intermediates include ethylene oxide, propylene oxide and butylene oxide. Tetrahydrofuran may also be used. Preferred alkylene oxides are ethylene oxide and propylene oxide. When both of these oxides are utilized, they may be added simultaneously or in sequence to prepare statistic or block polymer surfactants. The alkylene oxides, for example, ethylene oxide, may also be used alone.

Pesticides which are useful in the formulations of this invention are those that have a melting point under 1200 C; preferably under 110 0 C; most preferably under 90° C.

Suitable pesticides can be selected for example from the following classes of pesticidally active substances: acetanilides nitroxylenes benzoates organophosphorous compounds benzofurans oxidiazoles chlorinated hydrocarbons phenoxyphenoxyalkane carboxylic acid derivatives hydroxybenzonitriles pyrethroids and imidazoles triazoles nitroanilines Suitable acetanilides are in particular compounds of the type described in United States patent numbers 3,442,945 and 3,547,620, especially 2-chloro-2'6'-diethyl-N- (methoxymethyl)-acetanilide (alachlor). Suitable benzoates are in particular compounds of the type described in Great Britain patent number 1,247,817 especially 3-chloro- -ethoxyimino-2,6-dimethyloxybenzyl benzoate (benzoximate). Suitable benzofurans are in particular compounds of the type described in Great Britain patent number 1,271,659, especially 2-ethoxy-2,3-dihydro-3,3-dimethyl-5-benzofuranyl methane sulfonate (ethofumesate). Suitable chlorinated hydrocarbons are in particular compounds of the type described in United States patent number 2,799,685, especially 6,7,8,9,10,10hexachloro-l,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzo-dioxathiepin-3-oxide WO 99/33340 PCT/US98/27358 (endosulfan). Suitable hydroxybenzonitriles are in particular compounds of the type described in United States patent numbers 3,397,054 and 4,332,613, especially the esters of 3,5-dibromo-4-hydroxyphenyl cyanide (bromoxynil) and 3,5-diiodo-4-hydroxyphenyl cyanide (ioxynil). Suitable imidazoles are in particular compounds of the type described in Great Britain patent number 1,469,772, especially N-propyl-N-[2-(2,4,6trichlorophenoxy)-ethyl]- 1 H-imidazole-1-carboxamide; also compounds described in United States patent number 3,658,813, especially I-[2-(2,4-dichlorophenyl)-2-(2propenyloxy)-ethyl]-1H-imidazole (imazalil). Suitable nitroanilines are in particular compounds of the type described in United States patent number 3,257,190, especially Nbutyl-N-ethyl-2,6-dinitro-4-trifluoromethyl-aniline (benfluralin) or 2,6-dinitro-N,Ndipropyl-4-trifluoro-methyl aniline (trifluralin). Suitable nitroxylenes are in particular compounds of the type described in United States patent number 3,385,862, especially N- 1(1-ethylpropyl)-2,6-dinitro-3,4-xylidine (pendimethalin). Suitable organophosphorous compounds are in particular compounds of the type described in United States patent number 3,244,586, especially O,O-diethyl-O-(3,5,6-trichloro-2-pyridyl)-phosphorothioate (chlorpyrifos ethyl) and O,O-dimethyl-O-(3,5,6-trichloro-2-pyridyl)-phosphorothioate (chlorpyrifos methyl); also the compounds described in Great Britain patent number 974,138, especially 1,3-dithiolan-2-ylidene-phosphorimidate (phospholan); also the compounds described in United States patent numbers 3,230,230 and 3,240,668, especially 5-methoxy-2-oxo-1,3,4-thiadiazol-3-(2H)-yl -methyl -0,0dimethylphosphoro-dithioate (methidathion); also the compounds described in United States patent number 3,205,253, especially O,O-diiso-propyl-S-2-phenyl-sulphonylaminoethyl-phosphoro-dithioate (bensulfide); also the compounds described in United WO 99/33340 WO 9933340PCTIUS98/27358 States patent number 2,978,479, especially ethyl-3-methyl-4-(methylthio)-phenylisopropyl-phosphoramodate (fenamiphos). Suitable oxidiazoles are in particular compounds of the type described in United States patent number 3,385,862 especially 3- [2,4-dichloro-5-( I-methyl-ethoxy)-phenyl]-5 -dimethyl-ethyl)- 1,3 ,4-oxadiazole-2- (3H)-one (oxadiazon). Suitable phenoxy-phenoxy-alkane-carboxylic acid derivatives are in particular compounds of the type described in West German patent number 2,136,828 and 2,223,804, especially methyl-2-[4-(2,4-dichlorophenoxy)-phenoxy]-propanoate (diclofop methyl). Suitable pyretliroids are in particular compounds of the type described in Great Britain patent number 1,413,491 especially (3-phenoxy-phenyl)-methyl-3-(2,2dichloroethenyl)-2,2-dimethyl-cyclopropane-carboxylate (permethrin) and cyano-(3phenoxy-phenyl)-methyl-3-(2,2-dichloroethenyl).2,2..dimethyl..cyclopropane-carboxylate (cypermethrin); also 2-methyI-biphenyl-3-yl-methyl-(Z)-(IRS)-cis-3-(2-chloro-3,3 ,3trifluoro-prop- 1-enyl) 2,2-dimethyl-cyclopropane-carboxylate (hi fenthrin); also the compounds described in United States patent number 4,062,698, especially cyano-(3phenoxy-phenyl)-methyl-(RS)-2-(4-chloro-phenyl)-3-methyl butyrate (fenvalerate).

Suitable triazoles are in particular compounds of the type described in Israel patent number 73,450, especially 2-(4-chlorophenyl)-2-( 1,2,4-triazole- 1-yl-methyl) hexanitrile (myclobutanil); also the compounds described in Great Britain patent number 1,522,657, especially 1 -[2-(2,4-dichlorophenyl)-4-propyl- 1,3-dioxolan-2-yl-]-methyl- 1H- 1,2,4-triazole (propiconazole).

The preferred pesticidal actives include dithiopyr (S,S'-dimethyl 2- (dfurmty)4(-ehlrpl)6(rfurmty)35prdn dicarbothloate; chlorpyrifos (0,0-diethyl O-(3,5, 6 -trichloro-2-pyridyl)-phosphorothioate; iprodione (3- WO 99/33340 PCT/US98/27358 (3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxo- -imidazolidine carboxamide); and oxyfluorfen (2-chloro-l-(3-ethoxy-4-nitrophenoxy)-4-(trifluoro methyl benzene).

Organophosphorous compounds are antichlolinesterase chemicals which damage or destroy chlolinesterase, the enzyme required for nerve function in the animal body.

Organophosphorous insecticides, owing primarily to their ester nature, offer fundamental advantages in that they can be easily degraded hydrolytically, enzymatically, or biologically.

Organophosphorous compounds including those disclosed in U. S. Patent 3,244,586 and specifically those with a halogen substitution, are known to be extremely useful as insecticides and are especially adapted to be employed as active toxicants in compositions for the control of a number of mite, insect, bacterial, and fungal organisms, such as beetles, ticks, worms, aphids, flies, roaches, cattle grubs, screw worms, trash fish, snails, ascarids, nematodes, roundworms, and Rhizoctonia solani (a plant pathogenic fungus).

The organophosphorous insecticides of the instant invention are preferably the phosphorothioates, phosphorodithioates, phosphoroamidates, phosphoroamidothioates, and phosphonothioates which have melting points below about 120 0

C.

WO 99/33340 PCT/US98/27358 More preferably, the organophosphorous compounds are of the following formulas: P- R3

I.

R

1

-X

or R2 i x P- X-

R

6 X- P 2

R

1

X

wherein X is each individually 0 or S; R' is substituted or unsubstituted, branched or unbranched lower alkyl, aryl, or aralkyl;

R

2 is RX or R'; R is XR 4 or NHR;

R

4 is substituted or unsubstituted lower alkyl, lower alkylene, vinyl, aryl, aralkyl, cyanoaryl, carboalkoxyalkyl, alkoxyalkyl, alkoxyaryl, alkoxycarbonylalkyl, aminocarbonyalkyl, alkylcarbamoylalkyl, alkylthioalkyl, or alkylthioaryl;

R

s is H, acetyl, or lower alkyl; and

R

6 is lower alkyl, dioxanyl, or thiodi-p-phenylene wherein, in the specification and claims of this disclosure "aryl" includes heteroaryl compounds and "substituted" includes halogen substitutions. Also, in the present specification and claims, the WO 99/33340 WO 9933340PCT/US98/27358 term "lower alkyl" and "lower alkoxy" refer to radicals of from 1 to 8 inclusive, carbon atoms.

Much more preferably, the aryl radicals are selected from the group consisting of substituted or unsubstituted phenyl, pyridinyl, pyrimidinyl, cyanophenyl, alkyithiophenyl, benzotriazinyl, phthalimidinyl, oxobenzoxazolyl, oxothiadiazolyl, carbalkoxybenzyl, morpholinocarbonylalkyl, nitrophenyl, oxobenzopyranyl, quinolyl, pyridazinyl, pyrazinyl, quinoxalinyl, pyrazolyl, triazolyl, and thiadiazolinonyl.

The most preferred insecticides of the instant invention are selected from the group consisting of: 0, 0-diethyl 0-3.5-dibromo-6-chloro-2-pyridyI phosphorothioate, 0, 0-diethyl 0-3,5,6-trichloro-2-pyridyl phosphorothioate, 0,0-diethyl O-3,4,56-tetrachloro-2-pyridyl phosphorothioate, 0,0-diethyl 0-3,4,6-trichloro-2-pyridyl phosphorothioate, 0,0 -(thiodi-4, 1 -phenylene) bis (0,0-dimethyl phosphorothioate), 0,6-ethoxycarbonyl-5-methyl pyrazolo pyrimidi-N-2-yl 0,0-diethyl phosphorothioate, 0-(4-bromo-2,5-dichlorophenyl) 0,0-diethyl phosphorothioate, O,0-dimethyl-0- (2,5-dichloro-4-iodophenyl) phosphorothioate, 0,0-diethyl 0-2-quinoxalinyl phosphorothioate 0-2,6-dichloro-4-methyl phenyl 0,0-dimethyl phosphorothioate, 0,0-diethyl S-carboethoxymethyl phosphorodithioate, 0,0-diethyl S-[(4-oxo- 1,2,3-benzotriazin-3(4H)-yl) methyl] phosphorodithioate, 0,0-dimethyl S-[(4-oxo-1I,2,3-benzotriazin-3(4H)-yl) methyl] phosphorodithioate, WO 99/33340 WO 9933340PCTIUS98/27358 S-(2-(formyl methyl aminol)-2-oxoethyl) 0,0-dimethyl phosphorodithioate, 0,0-dimethyl phosphorodithioate, S-ester with 4-(mercaptomethyl)-2-methoxy- 1 ,3,4-thiadiazolin-5-one, 0-ethyl S,S-dipropyl phosphorodithioate 0,0-diethyl-S-(N-isopropyl carbamoyl methyl) phosphorodithioate 0,0-dimethyl 1-methyl carbamoyl ethyl) thio) ethyl) phosphorodithioate, 0,S-dimethyl N-acetyl phosphoroamidothioate, 0,0-bis (p-chlorophenyl) acetimidoyl-phosphoroamidothioate,.

0,S-dimethyl phosphoroamidothioate, 0-butyl O-3,5-dichloro-2-pyridyl methyl phosphoroamidothioate, 0-isopropyl 0-3,5-dichloro-2-pyridyl methyl phosphoroamnidothioate, 0-sec-butyl 0-3 ,5-dichloro-2-pyridyl methyl phosphoroamidothioate, 0-isobutyl 0-3,5-dichloro-2-pyridyl methyl phosphoroamidothioate, 0-methyl 0-3,5,6-trichloro-2-pyridyl isopropyl phosphoroamidothioate, 0-methyl 0-3 ,5-dibromo-2-pyridyl isopropyl phosphoroamidothioate, 0-methyl 0-3,5-dichloro-2-pyridyl isopropyl. phosphoroamidothioate, 0-methyl 0-3,5-dibromo-2-pyridyl methyl phosphoroamidothio ate, 0-ethyl 0-3,5-dibromo-2-pyridyl methyl phosphoroamidothioate, 0-ethyl 0-3 ,5-dichloro-2-pyridyl methyl phosphoroamidothioate, 0-methyl 0-3,5-dichloro-2-pyridyl methyl phosphoroamidothioate, 0-methyl 0-3 ,5-dichloro-2-pyridyl ethyl phosphoroamnidothioate, 0-ethyl 0-3,5-dichloro-2-pyridyl-ethyl phosphoroamidothioate, 0-isopropyl 0-3 ,5-dibromo-2-pyridyl methyl. phosphoroamidothioate, i O-propyl 0-3,5-dichloro-2-pyridyl methyl phosphoroamidothioate, O-propyl O-3,5-dichloro-2-pyridyl propyl phosphoroamidothioate, 0-methyl O-3,4,6-trichloro-2-pyridyl isopropyl phosphoroamidothioate, propyl 3,5,6-trichloro-2-pyridyl methyl phosphoroamidate, methyl 3,5,6-trichloro-2-pyridyl isopropyl phosphoroamidate, O-p-cyanophenyl O-ethyl phenyl-phosphonothioate, 0-ethyl 0-(4-nitro phenyl) phenyl phosphonothioate, and O-ethyl S-phenyl ethyl phosphonodithioate.

The very most preferred insecticide for use in the instant invention is O,O-diethyl 0-(3,5,6-trichloropyridine-2-yl) phosphorothioate also known as chlorpyrifos.

These aforelisted organophosphorous compounds are known to be very effective for the control of many parasitic organisms, particularly those found on the roots or aerial portions of growing plants inclusive of aphids, mites, plant pathogens, and insects. These compounds are effective at low concentrations, against chewing and sucking types of 15 insects, such as southern armyworm (Prodenia eridania), California red scale (Aonidiella aurantil), and Mexican bean beetle (Epilachna varivestis). They are also extremely useful for the impregnation of soil in nematocidal concentrations for the control of nematodes such as the root-knot nematode. An additional advantage to the use of these compounds is that they can be applied to soil in and around growing vegetation in amounts required for pest control without significant injury to plants.

o Furthermore, as a result of the high level of insecticidal activity of these compounds, only a few pounds, from about 0.25 to about 5 pounds, of active ingredient per acre per application is usually the recommended use rate, that is from about 0.1 to about 2.3 kilograms of active ingredient per 0.4 hectare per application is usually *25 the recommended use rate.

25 the recommended use rate.

[I:\DayLib\LIBZZ]05003.doc:mrr WO 99/33340 PCT/US98/27358 The organophosphorous compounds which are particularly useful in this invention are those that have melting points below about 120 0 C; preferably below about 110 0 C; and most preferably below about 90 0

C.

To form the enhanced emulsifiable concentrates of this invention, the aforementioned solid insecticides are melted and dissolved in a low VOC water-soluble solvent prepared by highly alkoxylating a mixture of fatty acids and rosin acids; preferably a tall oil mixture.

The nonionic surfactants useful in the formulations of this invention must have significant solubility in water. The H.L.B. of the nonionic surfactants should preferably be in the solubilizer/wetting agent range of from about 12 to about Examples of such nonionic materials are the following: 1) block-polymeric polyether glycols obtained, for example, by the addition of ethylene oxide on a condensation product of propylene oxide with propylene glycol; 2) alkoxylated alkyl phenols, alkylphenol-polyalkylene oxide condensates which are condensation products of alkylphenols with at least one alkylene oxide; 3) alkoxylated triglycerides; 4) alkoxylated di- or tri-styryl phenols; alkoxylated sorbitol fatty esters; 6) condensation products of aliphatic alcohols with at least one alkylene oxide; 7) condensation products of ethylene oxide with the products resulting from WO 99/33340 PCT/US98/27358 the reaction ofpropylene oxide and ethylene diamine; 8) ammonia, monoethanol and diethanol amides of acyl fatty acids, wherein the acyl moieties are normally derived from naturally occurring glycosides, but can be derived synthetically; 9) various semi-polar, long chain nonionics including: i) tertiary amine oxides, ii) tertiary phosphine oxides; and iii) sulfoxides; polysiloxanes, preferably the alkoxylated polysiloxanes; and 11. mixtures thereof.

The preferred nonionic surfactants are the condensation products of aliphatic alcohols with at least one alkylene oxide and the alkoxylated alkyl phenols, especially the aliphatic ethoxylates and the alkylphenol polyethoxylates; the alkoxylated triglycerides such as ethoxylated and ethoxylated-propoxylated castor oil; and the alkoxylated sorbitol fatty esters. Most preferred are the aliphatic alcohol ethoxylates which are aliphatic alcohol polyethylene oxide condensates of aliphatic alcohols wherein the aliphatic chain contains from about 4 to about 20, preferably about 5 to about 12 carbon atoms in either a straight chain or branched chain configuration and condensed with ethylene oxide, the said ethylene oxide being present in amounts equal to 2 to 50 moles of ethylene oxide per mole ofaliphatic alcohol; preferably 5 to 25, most preferably 8-15. The aliphatic alcohol may be of primary, secondary or tertiary structure; preferably of a secondary structure.

The most preferred alcohol ethoxylate is an ethoxylated trimethyl secondary nonanol.

WO 99/33340 PCT/US98/27358 Examples of the ethoxylated alkyl phenols include nonyl phenol condensed with about 9.5 moles of ethylene oxide per mole of nonyl phenol; dodecylphenol condensed with about 12 moles of ethylene oxide per mole of phenol, diamyl phenol condensed with about 9 moles of ethylene oxide per mole of phenol; dinonyl phenol condensed with about 15 moles of ethylene oxide per mold of phenol; and diisooctyl phenol condensed with about 15 moles of ethylene oxide per mole of phenol. Commercially available nonionic surfactants of this type include the IGEPAL series of nonionics, those sold under the trademarks CO-630 and DAP-9 by Rhodia Inc.

Illustrative of the preferred polysiloxanes are those of the formula:

CH

3

CH

3 CH 3

CH

3 I I

I

H

3 C-Si-O- Si-O Si-O Si-CH 3 I I CI

I

CH

3

CH

3 n 3 O -(C 2

H

4 0)a (C 3 y x wherein n is from about 2 to about 6; a is from about 8 to about 25; and b is from 0 to about 25; and the oxyalkylene groups may be random or block mixtures; y is from 0 to about 5; x is from about 1 to about 5; and R is selected from the group consisting of hydrogen, C, C 4 alkyl, and a alkyl ester; or H C3 3

CH

3

CH

3

CH

3 I I I I I

H

3 C-Si-O Si-O Si- Si-CH 3 I I I I I

CH

3

CH

3 A G

CH

3 y x z WO 99/33340 PCT/US98/27358 wherein A is a linear or branched alkyl having about 6 to about 30 carbon atoms; G is a glycol moiety of the formula (OCH,CH 2 )m OR" wherein R' is a divalent alkylene group having about 2 to about 6 carbon atoms; R" is selected from the group consisting of hydrogen, C, C, alkyl, and a C, C 4 alkyl ester; m is about 8 to about 100; y is 0 to about 5; x is about 0.1 to about 2.5; and z is about 0.1 to about The primary components of the low VOC pesticidal emulsifiable concentrates of the instant invention have the following concentration ranges: the pesticide is present from 10 to 60 weight percent, preferably from 10 to 40 weight percent; the alkoxylated fatty acid/rosin acid mixture from 20 to 60 weight percent, preferably from 30 to weight percent; and the nonionic surfactant from 15 to 45 weight percent, preferably from to 40 weight percent; all weight percents being based on the total weight of the emulsion concentrate.

The liquid pesticide, alkoxylated fatty acid/rosin acid mixture, and nonionic surfactant concentrates, the low VOC compositions of this invention, can be used to prepare stable oil-in-water emulsions. When these emulsions in water (EW's) are desired, the preferred concentration ranges of the components based on the total weight of the aqueous emulsion are as follows: the pesticide should be present from 1 to 50 weight percent; the alkoxylated fatty acid/rosin acid composition should be present from 2 to weight percent; and the nonionic surfactant from about 1.5 to 35 weight percent. The water can be present up to about 78 weight percent.

The ability of the concentrates of this invention to form stable emulsions when diluted with water is especially important for the dispersion stability allows for a WO 99/33340 PCT/US98/27358 homogeneous distribution of active ingredients on application targets, which assists in enhancing biological efficacy.

The agrochemical compositions according to the invention may optionally comprise: a) an anionic surfactant, such as i) partial sulfate and phosphate esters of polyoxyalkylene or (ii) carboxylate surfactants and their salts; and/or b) other nonionic surfactants, for example, polyoxyalkylene ethers of aliphatic alcohol having from 6 to 30, preferably from 10 to 20, and more particularly from 12 to 16 carbon atoms in the aliphatic residue; and/or c) a long chain carboxylic acid having from 10 to 25 carbon atoms such as caproic acid, caprylic acid, capric acid, lauric acid, myristic acid, palmitic acid, palmitoleic acid, margaric acid, stearic acid, oleic acid, linoleic acid, linolenic acid, and arachidic acid; and/or d) a lower alkanol ester of a long chain C 22 carboxylic acid, such as, for example, oleic, linoleic, linolenic, stearic, myristic, and palmitic acids; and/or e) an acidulated soap stock, said soap stock being a by-product of alkali refining of crude vegetable or animal fats and oils such as oils extracted from soybeans, canola, corn, cottonseed, olives, sunflower, safflower, sesame, peanut, rapeseed and rice; acidulated soybean soapstock being the preferred soapstock.

The agrochemical compositions of this invention may also comprise anti-freezing agents, anti-foam agents, compatibility agents, oxidation and U.V. protectants, WO 99/33340 PCTUS98/27358 bactericides, and pH buffering agents. Anti-foam agents decrease and/or prevent foaming when the solution containing the pesticidally-active formulation is agitated or sprayed.

Compatibility agents function to allow and maintain an emulsification of two or more ingredients that would otherwise separate when mixed. Buffering agents function to moderate the pH of the water in the tank solution.

The concentrated formulations of this invention can be prepared preferably by melting one or more of the water-insoluble pesticidally-active ingredients and physically blending this molten material with the alkoxylated fatty acid/rosin acid solvent. The nonionic surfactant composition and any optional ingredients are then added to the mixture using standard emulsifiable concentrate preparation methods well known in the art. The sequence of addition is not a critical feature of the invention. Furthermore, the ingredients can also be premixed prior to the application of heat.

In carrying out the methods of the present invention, the undesirable pests can be controlled by contacting the organism, its habitat, and/or its food supply prior to ingestion with a pesticidally effective amount of a formulation comprising the emulsifiable concentrates of this invention containing the agrochemical active. The term "comprising the emulsifiable concentrate(s)" is meant to include the emulsion concentrate(s) of this invention neat or after being diluted with water. These liquid formulations can be applied to living plants without substantial injury to the foliage thereof. When the compositions of the instant invention are applied as emulsifiable concentrates, the toxicant can be present in a concentration of from about 10 to about 60 percent by weight based on the total weight of the emulsion concentrate.

WO 99/33340 PCT/US98/27358 The exact concentration of the organochemical pesticide employed in an aqueous emulsion for application to the pest, its habitat or food can vary provided a pesticidal dosage of toxicant is supplied either on the organism, to its environment, or in its food.

This dosage of toxicant is primarily dependent upon the susceptibility of a particular organism to the specific pesticide compound. The emulsifiable concentrates of this invention are readily emulsified in water to form sprays containing the active toxicant in any commercially desired amount. Good results are obtained with the aqueous emulsifiable concentrates of this invention so diluted with water to form, for example, spray mixtures that the toxicant is present in the final diluted aqueous composition from about 0.5 to 2000 parts or more by weight per million.

Other than in the operating examples, or where otherwise indicated, all numbers expressing quantities of ingredients or reaction conditions used herein are to be understood as modified in all instances by the term "about".

The following examples serve to illustrate, but not limit, the invention. All parts and percentages are by weight, unless otherwise noted.

Example 1 Rosin acid-fatty acid (RFA) compositions having approximately the following composition: abietic acid (21-22 weight percent), palustric acid (2-3 weight percent), pimaric acid (7-8 weight percent), various isomers of the abietic, palustric and primaric acids and similar cyclic acids (6-7 weight percent), oleic acid (15-16 weight percent), linoleic acid (11-12 weight percent), isomers of 9 and C 0 acids (9-10 weight percent), and dimer and higher fatty acids (17-18 weight percent) are ethoxylated such WO 99/33340 PCT/US98/27358 that a series of ethoxylated rosin acid-fatty acid compositions are prepared having a molar addition of approximately 9, 12, 16 and 20 ethylene oxide moieties per molecule of acid.

Varying amounts of dithiopyr, a pre-emergent herbicide, are blended with the above described compositions and the non-alkoxylated rosin acid-fatty acid starting composition as a control. The samples are heated in an oven to a temperature above the melting point of the dithiopyr, in the range of from about 65 0 C 70 0 C. After the herbicide has melted, the samples are well agitated and subsequently cooled to room temperature. The samples are not disturbed for three weeks at the end of which time observations are made on the solution solubilities. The results are as indicated in Table I.

Table I Solubility of Dithiopyr in Ethoxylated Rosin-Fatty Acid (RFA) Compositions at Room Temperature Three Weeks After Blending Dithiopyr (Weight Percent) RFA (OEO) RFA(9EO) RFA(12EO) RFA(16EO) NT* NT NT NT NT NT *NT Not Tested; the dithiopyr was relatively insoluble in the blend.

Stable, One Phase Unstable, Multi-Phased Solution Slight Crystal Formation Commercial dithiopyr concentrate loadings using highly volatile organic compound (high VOC) solvents typically are within the range of from about 10 to 14 weight percent active ingredient with most being in the range of from about 12 to 13 weight percent, based on the total weight of the concentrate.

23 WO 99/33340 PCT/US98/27358 The above results illustrate the significant increase in stable, single phase solubility that can be achieved for a moderate to low melting, water insoluble pesticide without VOC solvents via the use of rosin-fatty acid compositions that have been ethoxylated to yield RFA compositions having molar additions of from about 9 to about 16 ethylene oxide moieties per molecule of acid.

Example II A series of tests are conducted in a manner identical to the tests conducted in Example I except that chlorpyrifos is substituted for the dithiopyr pesticide utilized in that Example. The results are as indicated in Table II below.

Table II Solubility of Chlorpyrifos in Ethoxylated Rosin-Fatty Acid Compositions at Room Temperature Three Weeks After Blending Chlorpyrifos (Weight RFA (9EO) RFA(12EO) RFA(16EO) RFA(20 EO) Percent) NT NT NT NT NT NT NT NT NT NT NT NT As in Example I, maximum pesticidal solubilities and stability are realized with ethoxylation between about 9 and 16.

Example III Solutions are prepared as in Example I with four pesticides, chlorpyrifos, dithiopyr, oxyfluorfen, and iprodione at different weight percent loadings in the WO 99/33340 PCT/US98/27358 ethoxylated rosin-fatty acid composition of Example I having a molar addition of the ethylene oxide moiety per molecule of acid of about 16. The chlorpyrifos is an insecticide; the dithiopyr a pre-emergent herbicide; the oxyfluorfen a pre-and postemergent herbicide; and the iprodione is a contact fungicide. As in Example I, the solutions are cooled to room temperature and stored undisturbed for three weeks at which time solubility/stability observations are made. The results are set forth in Table III.

Table III Solubility of Various Pesticidal Compounds in RFA (16 EO) at Room Temperature Three Weeks After Blending Weight Percent Chlorpyrifos Dithiopyr Oxyfluorfen Iprodione NT NT NT NT NT NT NT NT NT NT NT Stable, Single Phase Solution Unstable, Multi-Phased Solution NT Not Tested The above results illustrate that the water-soluble 16 EO ethoxylated rosin acidfatty acid compositions of this invention can provide excellent stable solvents in the absence of highly volatile organic compounds (high VOC's) for a wide variety of waterinsoluble pesticides.

Example IV Four samples are prepared by mixing in a weight ratio of 4:1, the RFA (9EO) composition of Example I with nonionic surfactant, namely, ethoxylated diamylphenol.

WO 99/33340 PCT/US98/27358 The average ethylene oxide molar addition per mole of the diamylphenol is 9. Dithiopyr is blended into the RFA (9EO)/nonionic surfactant solvent system at various concentrations; heated; agitated; and cooled to room temperature as in Example I. The samples are stored for three weeks and solubility/stability observations made at the end of that time. The results are as set forth in Table IV.

Table IV Solubility of Dithiopyr in a 4:1 (Weight:Weight) RFA (9EO): Diamvlphenol (9EO) Solvent RFA (9EO): Diamylphenol (9EO) (4:1, Dithiopyr (Weight Percent) Weight:Weight) Stable, Single Phase Solution Unstable, Multi-Phase Solution The above results illustrate the synergistically increased solubility that can be realized above that of the ethoxylated RFA compositions alone (see Example I) when nonionic surfactant is present as a co-solvent/ solubility aid.

Example V Incrementally different amounts of chlorpyrifos are blended with 1) the rosin-fatty acid (16EO) ethoxylated composition of Example I; and 2) a 4:1 (weight:weight) blend of this RFA (16EO) with an ethoxylated nonylphenol (9EO) nonionic surfactant. These samples are heated in an oven to above the melting point of the chlorpyrifos. The samples are then well agitated and subsequently cooled to room temperature. The samples are left undisturbed for three weeks at the end of which time observations are 26 27 made on the solution solubilities. The results are set forth in Table V. Concentrations are indicated in pounds of active ingredient per gallon of total formulation, 5E represents pounds a.i. per gallon of formulated product, and in approximate metric equivalents.

Table V Chlorpyrifos Solubilities Chlorpyrifos Concentration RFA (16EO) RFA (16EO): NP9* (4:1, Weight:Weight) 1E (0.45 kg a.i. per 3.4L) 2E (0.9 kg a.i. per 3.4L) 3E (1.4 kg a.i. per 3.4L) 4E (1.8 kg a.i. per 3.4L) (2.3 kg a.i. per 3.4L) 6E (2.7 kg a.i. per 3.4L) *Nonylphenol Ethoxylated with 9EO/Molecule (Av.) Surfactants, primarily nonionics, are known to enhance the penetration and distribution of water and crop protection chemicals into the soil and rootzone.

Serendipitously, when certain nonionic surfactants are co-formulated with the RFA ethoxylated compositions of this invention and used as co-solvent/stabilizers, the pesticidal loading levels can be increased and the stability of the overall formulations can be improved over that of the individual components.

Example VI Technical dithiopyr is melt blended into 1) the RFA (16EO) compositions of 15 Example I; 2) a nonylphenol ethoxylate (9EO and 3) a 4:1 (Weight:Weight) blend of the RFA (16 EO) and the nonylphenol (9EO). Solution/stability observations are made after three weeks as described in Example I. The results are set forth in Table VI.

0 0 0S *0

S.

0000 00 00*0 0 0 0 009* 0 0 000

S

0 00000 0 96 00 0.

00 0000 0 000.

0 00 0 000 0 [1:\DayLib\LIBZZ]05003.doc:mrr WO 99/33340 PCT/US98/27358 Table VI Dithipyr Solubility Dithiopyr RFA(16EO): NP(9 EO) (Weight Percent) NP* (9EO) RFA (16EO) Weight:Weight) *Nonylphenol Ethoxylate The dithiopyr loading limit in the nonylphenol ethoxylate is about 10% in the rosin acid-fatty acid ethoxylate (16EO) about 20%; and in the rosin acid-fatty acid ethoxylate (16EO) NP9 blend, it synergistically increased to about 25 weight percent.

Example VII Emulsifiable concentrates (EC's) of the instant invention with pesticidal compositions as indicated in Table VII below are prepared as in Example V. The compositions are then diluted with water in a 10 water to 1 EC ratio to form aqueous spray emulsions. Two commercial emulsifiable concentrates, both containing high VOC's, MICRO-FLO chlorpyrifos, a 2E emulsifiable concentrate trademark of the Micro Flo Company and DIMENSION IE, a trademark of Rohm Haas for a 12.7 weight percent dithiopyr in a heavy aromatic petroleum naphtha emulsifiable concentrate, are similarly diluted to form aqueous spray emulsions.

The visual appearance and stability of the spray solutions, as determined by the appearance of a multi-phased system, are as indicated in Table VII below.

WO 99/33340 PCT/US98/27358 Table VII Spray Emulsion Composition Low VOC's Appearance Stability Micro-Flo Chlorpyrifos 2E No Cloudy 2 Hours RFA (16EO)/NP9 Chlorpyrifos 2E Yes Cloudy 24 Hours Dimension IE (12.7% Dithiopyr) No Cloudy 24 Hours RFA (16EO) Dithiopyr Yes Cloudy 24 Hours RFA (16EO)/NP9 Dithiopyr Yes Clear to Cloudy 48 Hours Thus, the aqueous spray emulsions prepared from the low VOC emulsifiable concentrates of the instant invention exhibit improved stability as compared to standard, commercially available emulsifiable concentrates containing high VOC's.

In addition to the enhanced stability and solubility properties achieved by the liquid pesticidal emulsifiable concentrates of this invention, advantages of the instant low VOC pesticidal compositions include reduced worker exposure to high VOC's; greater options for shipping formulated pesticides; advantageous labeling options; and decreased regulatory issues.

Furthermore, it has also been observed that the instant formulations unexpectedly reduce the odor of odoriferous pesticidally active ingredients. Formulations of chlorpyrifos in the ethoxylated fatty acid/rosin acid and/or ethoxylated fatty acid/rosin acid-nonionic surfactant solvent systems of this invention significantly reduce the odor of the pesticide in both the formulated emulsifiable concentrate and the diluted aqueous 29 WO 99/33340 PCTIUS98/27358 spray preparations. The odor reduction was apparent even when a low odor chlorpyrifos technical active material was used.

Example VIII Rosin acid-fatty acid (RFA) compositions having approximately the following composition: abietic acid (21-22 weight percent), palustric acid (2-3 weight percent), pimaric acid (7-8 weight percent), various isomers of the abietic, palustric and primaric acids and similar cyclic acids (6-7 weight percent), oleic acid (15-16 weight percent) linoleic acid (11-12 weight percent), isomers of C 18 and C 20 acids (9-10 weight percent), and higher fatty acids (17-18 weight percent) are ethoxylated such that ethoxylated rosin acid-fatty acid compositions are prepared having a molar addition of approximately 16 ethylene oxide moieties per molecule of acid.

Technical chlorpyrifos, a solid, organophosphorous insecticide, O,0-diethyl 0- 3 ,5,6-trichloro-2-pyridyl) phosphorothioate, is blended with the above-described alkoxylated rosin acid-fatty acid composition together with a secondary alcohol ethoxylate, Tergitol TMN-6, a trademark of Union Carbide for an ethoxylated trimethyl nonanol.

The mixture is heated in an oven to above the melting point of the chlorpyrifos, in the range of from about 41.5 0 C to about 43.5 0 C. After the insecticide is melted, the sample is well agitated and subsequently cooled to room temperature.

The low VOC, emulsifiable concentrate has the following formulation (in weight percent based on the total formulation weight): 31 Rosin Acid/Fatty Acid Ethoxylate 53.2 weight percent Chlorpyrifos 25.5 weight percent Tergitol TMN-6 21.3 weight percent Example IX The low VOC, emulsifiable chlorpyrifos concentrate of Example VIII, having about 2 pounds of chlorpyrifos per gallon (approximately 0.9 kg per 3.4L) hereinafter identified as Chlorpyrifos 2E, is diluted in water to form an aqueous spray composition.

Field evaluations are conducted from June 19 through July 17 using replicated field plots. The target pest during this season trial is the Tawny Mole Cricket. The Chlorpyrifos 2E formulation of the instant invention is applied at 1, 2, and 3 pounds of active ingredient per acre approximately 0.45, 0.9, and 1.4 kg of active ingredient per 0.4 hectare). For comparison purposes, Dursban 4E, a commercial chlorpyrifos insecticide formulation sold by The Dow Chemical Company is also applied at 1, 2, and 3 pounds of active ingredient per acre approximately 0.45, 0.9, and 1.4 kg of active 15 ingredient per 0.4 hectare). Also for comparison purposes, Orthene 75S, an acephate, i.e., O,S-dimethyl acetyl phosphoramidothioate insecticide formulation sold by the Valent U.S.A. Corp. is applied at 2.25 pounds active ingredient per acre approximately 1 kg active ingredient per 0.4 hectare). Control data, non-treated plot data is also monitored.

20 Mole Cricket damage ratings are determined prior to the treatment applications and subsequently at 1-2 week intervals. Treatments are applied with standard research plot equipment. The results of these trials are as indicated in Table VIII.

Table VIII Efficacy of Chlorpyrifos 2E Formulations on Early Season Control of Tawny Mole Cricket (St. Simons Island, GA) ai/acre* 19-June 26-June 3-July 17-July Low VOC 1(0.45kg/0.4 hectare) 3.72a** 1.88 bcd 2.20 bc 3.13 cd Low VOC 2 (0.9 kg/0.4 hectare) 3.70 a 1.48 c-f 1.575 cde 1.90 fg Low VOC 3 (1.4 kg/0.4 hectare) 3.60 a 0.58 f" 0.305 sh 0.65 h Dursban 1 (0.45 kg/0.4 hectare) Dursban 2 (0.9 kg/0.4 hectare) Dursban 3 (1.4 kg/0.4 hectare) Control 0 Orthene 75S 2.25(1 kg/0.4 hectare) OF- 4[I:\DayLib\LIBZZ]05003.doc:mrr I I 3.63 a 3.70 a 3.63 a 3.45 a 3.33 a 3.33 a 4.05 ab 2.25 bc 1.60 cde 2.65 def 2.27 bc 1.25 def 1.65g 3.50 a 3.50 a 4.38 a 3.55 a 1.83 bcd 1.55 cde 1.85 fg *ai/ac=lbs. ai/ac Means in columns followed by the same letter are not significantly different (P=0.05) The low VOC Chlorpyrifos 2E formulations of the instant invention consistently reduce Mole Cricket damage better than the commercial 4E Dursban formulation when applied at the same rate. More importantly, the low VOC Chlorpyrifos 2E formulation applied at the 2.0 lb. ai/acre approximately 0.9 kg ai/0.4 hectare) rate, while using one-third less active ingredient, is as efficacious as the 3.0 lb. ai/acre approximately 1.4 kg ai/0.4 hectare) treatment rate of the commercial Dursban formulation.

Furthermore, at 3.0 lb. ai/acre approximately 1.4 kg ai/0.4 hectare), the low VOC Chlorpyrifos 2E formulation is significantly more efficacious than the same treatment rate of the commercial Dursban 4E formulation.

Example X Field evaluations are conducted with the Chlorpyrifos 2E of Example IX from September 18 through October 23 using replicated field plots. The target pest is the 3 rd to 15 5 th instars of the Southern Masked Chafer. The chloripyrifos 2E formulation of the instant invention is applied at 2 and 3 pounds of active ingredient per acre approximately 0.9 and 1.4 kg of active ingredient per 0.4 hectare). For comparison purposes, Dursban 4E chlorpyrifos insecticide formulation is also applied at the identical rates of 2 and 3 pounds of active ingredient per acre approximately 0.9 and 1.4 kg of active ingredient per 0.4 hectare). Control data, non-treated plot data is also monitored.

The live grub damage ratings are determined prior to treatment application and subsequently at 1-2 week intervals. Treatments are applied with standard research plot equipment. The results of these trials are as indicated in Table IX.

Table IX Efficacy of Chlorpyrifos 2E on 3 rd-5th Instars of Southern Masked Chafer (St. Simons Island, GA) ai/acre 18 September 25 September 2 October 9 October 23 October Low VOC 2(0.9 kg/0.4 hectare) 46.33 a 25.27 bcd 38.83 ab 25.00 ab 24.60 ab Low VOC 3(1.4 kg/0.4 hectare) 56.07 a 17.83 d 12.67 cd 14.93 bc 8.90 bc Dursban 2(0.9 kg/0.4 hectare) 45.20 a 37.30 a-d 38.80 ab 33.93 ab 29.47 ab Dursban 3(1.4 kg/0.4 hectare) 60.27 a 41.97 a-d 42.33 ab 35.03 ab 35.03 a Control 0 46.33 a 43.50 ab 42.57 ab 44.60 a 42.57 a [I:\DayLib\LIBZZ05003.doc:mrr

I

33 The most effective chlorpyrifos formulation evaluated at this test location is the low VOC Chloripyrifos 2E formulation of the instant invention. Numbers of live larvae are significantly lower in plots receiving the 3.0 lb. ai/acre approximately 1.4 kg ai/0.4 hectare) treatment rate of the low VOC formulation. Neither the 2 nor the 3 pound per acre neither the approximately 0.9 nor the approximately 1.4 kg per 0.4 hectare) treatment rate of the Dursban chlorpyrifos formulation provides commercially acceptable larvae control.

Examples XI-XIII Field evaluations on the late season control of Tawny Mole Crickets are conducted to using replicated field plots in Georgia at Savannah, from September 3 through October 1; at St. Mary's from September 12 through October 17; and at St. Simons Island from September 18 through October 16. The Chlorpyrifos 2E formulation of the instant invention is applied at 2 and 3 pound of active ingredient per acre approximately 0.9 and 1.4 kg of active ingredient per 0.4 hectare). For comparison purposes, Dursban 4E 15 Chlorpyrifos insecticide formulation is also applied at the identical rates of 2 and 3 pounds of active ingredient per acre approximately 0.9 and 1.4 kg of active Singredient per 0.4 hectare). Also for comparison purposes, Orthene 75S acephate insecticidal formulation is applied at 2.25 pounds of active ingredient per acre approximately 1 kg of active ingredient per 0.4 hectare). Control data, non-treated plot data is also monitored.

Tawny Mole Cricket damage ratings are determined as in Example IX. Treatments are applied with standard research plot equipment. The results of these trials are as indicated in Tables X through XII.

Table X Efficacy of Chlorpyrifos 2E on Late Season Control of Tawny Mole Cricket (St. Mary's GA) ai/acre 12 September 26 September 3 October 17 October Low VOC 2 (0.9 kg/0.4 hectare) 3.93 ab 1.50 cde 0.87 def 0.97 e Low VOC 3 (1.4 kg/0.4 hectare) 3.90 ab 0.27 g 0.47 f 0.80 e Dursban 2 (0.9 kg/0.4 hectare) 3.20 c 2.67 b 2.40 b 2.57 b Dursban 3 (1.4 kg/0.4 hectare) 4.13a 1.63 cde 1.40 cd 1.60 cde Orthene 75S 2.25(1kg/0.4 hectare) 3.93 ab 1.10 def 0.70 def 2.03 bcd Control 0 3.70 abc 6.70 a 7.20 a 7.17 a [I:\DayLib\LIBZZ]05003.doc:mrr 34 Table XI Efficacy of Chlorpyrifos 2E on Late Season Control of Tawny Mole Cricket (Savannah, GA) ai/acre 3 September 10 September 17 September 1 October Low VOC 2 (0.9 kg/0.4 hectare) 5.53 a 2.10 def 1.90 ef 2.57 ef Low VOC 3 (1.4 kg/0.4 hectare) 5.80 a 1.10 f 1.10 f 1.43 g Dursban 2 (0.9 kg/0.4 hectare) 6.07 a 4.50 b 5.20 b 5.63 b Dursban 3 (1.4 kg/0.4 hectare) 5.87 a 4.03 bc 4.10 bc 4.50 cd Orthene 75S 2.25 (1kg/0.4 hectare) 5.47 a 1.13 f 2.13 ef 2.30 efg Control 0 5.40 a 6.10 a 7.30 a 9.00 a Table XII Efficacy of chlorpyrifos 2E on Late Season Control of Tawny Mole Cricket (St. Simons Island, GA) ailacre 18 September 25 September 2 October 16 October Low VOC 2 (0.9 kg/0.4 hectare) 3.87 abc 1.73 de 1.90 de 1.03 c-f Low VOC 3 (1.4 kg/0.4 hectare) 3.60 bc 0.77 f 1.07 f 0.30 f Dursban 2 (0.9 kg/0.4 hectare) 3.87 abc 2.87 b 3.50 b 2.5 b Dursban 3 (1.4 kg/0.4 hectare) 3.87 abc 1.97 cde 2.43 cde 1.67 b-e Orthene 75S 2.25 (1kg/0.4 hectare) 4.40 a 1.17 ef 1.90 de 0.83 def Control 0 3.90 abc 5.27 a 6.03 a 7.23 a With respect to the control of late instar Mole Cricket nymphs and adults in the plots at St. Mary's, Georgia, both the treatments, the 2 and 3 pounds ai/acre approximately 0.9 kg and 1.4 kg ai/0.4 hectare) of the low VOC Chlorpyrifos 2E formulations of the instant invention provide significantly better control than one achieves by similar rates with the commercial Dursban 4E chlorpyrifos insecticidal formulation.

The 3.0 lb. ai/acre approximately 1.4 kg ai/0.4 hectare) low VOC Chlorpyrifos 3E formulation is significantly more efficacious than the 2.0 lb./acre approximately 0.9 kg ai/0.4 hectare) treatment rate. The 2.0 lb. ai/acre approximately 0.9 kg ai/0.4 hectare) treatment by the Chlorpyrifos 2E formulation of the instant invention is equivalent to the 3.0 lb. ai/acre approximately 1.4 kg ai/0.4 hectare) rate of the commercial Dursban formulation. While the commercial Dursban formulation significantly reduces mole cricket damage as compared to the untreated control, T! performance is inferior to the low VOC Chlorpyrifos 2E formulation. Similar results are

S..

obtained at the other two locations where the low VOC chlorpyrifos formulations of the instant invention are evaluated.

In summary, the results of the trials as reported in Examples IX-XIII clearly indicate that the low VOC organophosphorous formulations of the instant invention significantly enhance the control of pests, especially soil inhabiting insect pests while [I:\DayLib\LIBZZ]05003.doc:mrr WO 99/33340 PCT/US98/27358 concomitantly reducing pesticide application rates, worker exposure to applied materials levels, and the overall pesticide loadings on the environment.

As is evident from the foregoing, various modifications are contemplated in the practice of the invention. Although the invention is described with respect to specific modifications, the details thereof are not to be construed as limitations except to the extent indicated in the following claims.

Claims

1. An agrochemical emulsifiable concentrate comprising: a) from about 10 to about 60 percent by weight of a water-insoluble pesticide having a melting point of less than about 1200C; b) from about 20 to about 60 percent by weight of an alkoxylated acid composition wherein said acid composition comprises: i) from greater than about 25 to about 60 percent by weight alkoxylated rosin acids; and ii) from about 40 to less than about 75 percent by weight alkoxylated fatty o0 acids wherein the rosin acids and fatty acids have an average molar addition of from about 6 to about 20 alkoxy moieties per molecule of acid; the weight percents of the rosin and fatty acids being based on the total weight of said alkoxylated acids; and c) from about 15 to about 45 percent by weight of nonionic surfactant; wherein the weight percents are based on the total weight of the emulsifiable 15 concentrate except where indicated.

2. The agrochemical emulsifiable concentrate of claim 1 wherein the pesticide is selected from the group consisting of: i) acetanilides; ii) benzoates; 20 iii) benzofurans; iv) chlorinated hydrocarbons; v) hydroxybenzonitriles; vi) imidazoles; vii) nitroanilines; viii) nitroxylenes; ix) organophosphorous compounds; x) oxidiazoles; xi) phenoxy-phenoxy-alkane-carboxylic acid derivatives; xii) pyrethroids; xiii) triazoles; and xiv) mixtures thereof.

3. The agrochemical emulsifiable concentrate of claim 1 wherein the rosin acid is selected from the group consisting of: T i) abietic acid; ii) neoabietic acid; [I:\DayLib\LIBZZ05003.doc:mrr iii) palustric acid; iv) dehydroabietic acid; v) pimaric acid; vi) tetrahydroabietic acid; and vii) mixtures thereof.

4. The agrochemical emulsifiable concentrate of claim 1 wherein the fatty acid is selected from the group consisting of: i) oleic acid; ii) linoleic acid; iii) conjugated linoleic acid; iv) palmitic acid; v) stearic acid; and vi) mixtures thereof. The emulsifiable concentrate of claim 1 wherein the nonionic surfactant is selected from the group consisting of: 1) block-polymeric polyether glycols; 2) alkoxylated alkyl phenols: 3) alkoxylated triglycerides; 4) alkoxylated di- or tri-styryl phenols; alkoxylated sorbitol fatty esters; 6) condensation products of aliphatic alcohols with at least one alkylene oxide; 7) condensation products of ethylene oxide with the products resulting from the reaction of propylene oxide and ethylene diamine; 8) Ammonia, monoethanol and diethanol amides of acyl fatty acids; 9) Semi-polar, long chain nonionics selected from the group consisting of i) tertiary amine oxides; ii) tertiary phosphine oxides; and iii) sulfoxides; polysiloxanes or alkoxylated polysiloxanes; and 11) mixtures thereof.

6. The emulsifiable concentrate of claim 1 wherein the nonionic surfactant is ed from the group consisting of nonylphenol ethoxylated with 9 ethylene oxide ies (9EO) per nonylphenol molecule; ethoxylated diamylphenol (9EO); ethoxylated select moiet I :\DayLib\LIBZZ]O5003doc:mrr 1. 1 1 .i 39 tributylphenol (9EO); ethoxylated 2,4-ditertiary butyl phenol (9EO); and ethoxylated disecondary butylphenol (9EO).

7. The emulsifiable concentrate of Claim 1 wherein the nonionic surfactant is selected from the group consisting of primary, secondary, and tertiary aliphatic alcohol ethoxylates.

8. The emulsifiable concentrate according to claim 6 wherein the alcohol exothylate is a secondary aliphatic alcohol ethoxylate.

9. The emulsifiable concentrate of claim 1 wherein the nonionic surfactant is an ethoxylated trimethyl nonanol.

10. The emulsifiable concentrate of claim 1 wherein the nonionic surfactant is a polysiloxane or an alkoxylated polysiloxane.

11. The emulsifiable concentrate according to claim 1, wherein the water-soluble pesticide has a melting point of less than about 110°C.

12. The emulsifiable concentrate according to claim 1, wherein the water-soluble pesticide has a melting point of less than about 90 0 C.

13. The emulsifiable concentrate according to claim 1, wherein said acid composition comprises from 30 to 40 weight percent alkoxylate rosin acid.

14. The emulsifiable concentrate according to claim 1, wherein said acid composition comprises from about 60 to about 70 weight percent fatty acids.

15. The emulsifiable concentrate according to claim 1, wherein the rosin acids and fatty acids have an average molar addition of from about 9 to about 16 alkoxy moieties per molecule of acid.

16. An agrochemical emulsifiable concentrate according to claim 1, substantially as hereinbefore described with reference to any one of the examples.

17. An organophosphorous insecticidal emulsifiable concentrate comprising: a) from about 10 to about 60 percent by weight of an organophosphorous insecticide having a melting point of less than about 120 0 C; b) from about 20 to about 60 percent by weight of an alkoxylated acid composition wherein said acid composition comprises: i) from greater than about 25 to about 60 percent by weight alkoxylated rosin acids; and ii) from about 40 to less than about 75 percent by weight alkoxylated fatty acids wherein the rosin acids and fatty acids have an average molar addition of from ST out 6 to about 20 alkoxy moieties per molecule of acid; the weight percents of the rosin an tty acids being based on the total weight of said alkoxylated acids; and OF ayLib\LIBZZ]05003.doc:mrr SI I j c) from about 15 to about 45 percent by weight of nonionic surfactant; wherein the weight percents are based on the total weight of the emulsifiable concentrate except where indicated.

18. The emulsifiable concentrate of claim 17 wherein the organophosphorous insecticide is selected from the group consisting of: i) phosphorothioates; ii) phosphorodithioates; iii) phosphoroamidates; iv) phosphoroamidothioates; and v) phosphonothioates.

19. The emulsifiable concentrate of claim 17 wherein the organophosphorous insecticide is a compound of the formula: R 2 X I. R2X X R2 SP-R3 R- X R2or 9 SR is H, acetyl, or lower alkyl; and Sis lower alkyl, dioxanyl, or20 II. wherein X is each individually 0 or S; R' is substituted or unsubstituted, branched or unbranched lower alkyl, aryl, or aralkyl; R isR'XorRl; R 3 isXR 4 orNHR 5 R 4 is substituted or unsubstituted lower alkyl, lower alkylene, vinyl, aryl, aralkyl, cyanoaryl, carboalkoxyalkyl, alkoxyalkyl, alkoxyaryl, alkoxycarbonylalkyl, aminocarbonyalkyl, alkylcarbamoylalkyl, alkylthioalkyl, or alkylthioaryl; R 5 is H, acetyl, or lower alkyl; and m^fi ^sR 6 is lower alkyl, dioxanyl, or thiodi-p-phenylene. 3.doc:mrr 41 The emulsifiable concentrate of claim 19 wherein the aryl radicals are selected from the group consisting of substituted or unsubstituted phenyl, pyridinyl, pyrimidinyl, cyanophenyl, alkyithiophenyl, benzotriazinyl, phthalimidinyl, oxobenzoxazolyl, oxothiadiazolyl, carbalkoxybenzyl, morpholinocarbonylalkyl, nitrophenyl, oxobenzopyranyl, quinolyl, pyridazinyl, pyrazinyl, quinoxalinyl, pyrazolyl, triazolyl, and thiadiazolinonyl.

21. The emulsifiable concentrate of claim 17 wherein the organophosphorous insecticide is selected from the group consisting of: 0, 0-diethyl 0-3, 5-dibromo-6-chloro-2-pyridyl phosphorothioate, 0, 0-diethyl 03,5 ,6-trichloro-2-pyridyl phosphorothioate, 0,0-diethyl 0-3,4,5,6-tetrachloro-2-pyridyl phosphorothioate, 0,0-diethyl 0-3,4,6-trichloro-2-pyridyl phosphorothioate, 0,0-(thiodi-4, 1 -phenylene) bis (0,0-dimethyl phosphorothioate), 0,6-ethoxycarbonyl-5-methyl pyrazolo pyrimidi-N-2-yl 0,0-diethyl phosphorothioate, 0-(4-bromo-2,5-dichlorophenyl) 0,0-diethyl phosphorothioate, O,0-dimethyl-0-(2,5-dichloro-4-iodophenyl) phosphorothioate, 0,0-diethyl 0-2-quinoxalinyl phosphorothioate 0-2,6-dichloro-4-methyl phenyl 0,0-dimethyl phosphorothioate, 0,0-diethyl S-carboethoxymethyl phosphorodithioate, 0,0-diethyl S-[4-oxo- 1 ,2,3-benzotriazin-3 (4H)-yl) methyl] phosphorodithioate, 0,0-dimethyl S-[(4-oxo- 1,2,3-benzotriazin-3(4H)-yl) methyl] phosphorodithioate, -(2-(fony mtyaio)-2-oxoethyl) 0,0-dimethyl phosphorodithioate, 0,0-dimethyl phosphorodithioate, S-ester with 4-(mercaptomethyl)-2-methoxy- 1 ,3,4-thiadiazolin-5 -one, 0-ethyl S ,S-dipropyl phosphorodithioate 0,0-diethyl-S-(N-isopropyl carbamoyl methyl) phosphorodithioate 0,0-dimethyl S-(2-((l-methyl carbamoyl ethyl) thio) ethyl) phosphorodithioate, 0,S-dimethyl N-acetyl phosphoroamidothioate, 0,0-bis (p-chlorophenyl) acetimidoyl-phosphoroamnidothioate, 0,S-dimethyl phosphoroamidothioate, 0-butyl 0-3,5 -dichloro-2-pyridyl methyl. phosphoroamnidothioate, 0-isopropyl 0-3 ,5-dichloro-2-pyridyl methyl phosphoroamidothioate, ~STI 0-sec-butyl 0-3 ,5-dichloro-2-pyridyl methyl phosphoroamidothioate, K0-isobutyl 0-3 ,5-dichloro-2-pyridyl methyl phosphoroamidothioate, OF Lib\LIBZZ]05003.doc:mrr 42 0-methyl 0-3,5 ,6-trichloro-2-pyridyl i sopropyl phosphoroamidothioate, 0-methyl 0-3 ,5-dibromo-2-pyridyl isopropyl phosphoroamidothioate, 0-methyl 0-3 ,5-dichloro-2-pyridyl i sopropyl phosphoroamidothioate, 0-methyl 0-3,5 -dibromo-2-pyridyl methyl phospho roamidothioate, 0-ethyl 0-3 ,5-dibromo-2-pyridyl mnethyl phosphoroamidothioate, 0-ethyl 0-3,5 -dichloro-2-pyridyl mecthyl phosphoroamnidothioate, 0-methyl 0-3 ,5-dichloro-2-pyridyl miethyl phosphoro amidothioate, 0-methyl 0-3 ,5-dichloro-2-pyridyl ethyl phosphor-oarnidothioate, 0-ethyl 0-3 5S-dichloro-2-pyridyl-ethyl phospho roam i dothioate, 0-isopropyl 0-3,5 -dibromo-2-pyriclyl miethyl phosp~horoarnidothioate, 0-propyl 0-3, 5-dichloro-2-pyridyl miethyl phosphoroamildothioate, 0-propyl 0-3 ,5-dichloro-2-pyridyl propyl phosphoi-oarnidothioate, 0-methyl 0-3 4 ,6-trichloro-2-pyi-idyl isopropyl phosphoroamidothioate, propyl 3,5 ,6-trichloro-2-pyridyl methyl lphosphoroam i date, methyl 3,5 ,6-trichloro-2-pyridyl isopropyl phosph11Omoami 1idate, -0-p-cyanophenyl 0-ethyl phenyl-phosp honothioate, 0O-ethyl 0-(4-nitro phenyl) phenyl phosphonoth ioaie, and 0-ethyl S-phenyl ethyl phosphonodi thi oate.

22. The emulsifiable concentrate of claimi 1 7 wherein the organophosphorous insecticide is 0,0-diethyl 0-(3 .5 ,6-tricliloro pyridinc-2-yl) phosphorothioate.

23. The emulsifiable concentrate of claimi 17 \vhereinl the nonionic surfactant is selected f-rm the groupJ Consisting Of:* 1) block-polymeric polyether glycols; 2) alkoxylated alkyl phenols: 253) alkoxylated triglycerides; 4) alkoxylated di- or tri-styryl phenols; alkoxylated sorbitol fatty ester-s; 6) condensation products of aliphatic alcohols with at least one alkylene oxide; 7) condensation products of ethylene oxide with the products resulting from the reaction of propylene oxide and ethylene diamriine; 8) Ammonia, monoethanol and diethanol anildes of acyl fatty acids; 9) Semi-polar, long chain nonionics selected from the group consisting of i) tertiary amine oxides; 3 ~ii) tertiary phosphine oxidecs; and :.mrr r r 43 iii) sulfoxides; polysiloxanes or alkoxylated polysiloxanes; and 11) mixtures thereof.

24. The emulsifiable concentrate of claim 17 wherein the nonionic surfactant is selected from the group consisting of nonylphenol ethoxylated with 9 ethylene oxide moieties (9EO) per nonylphenol molecule; ethoxylated diamylphenol (9EO); ethoxylated tributylphenol (9EO); ethoxylated 2,4-ditertiary butyl phenol (9EO); and ethoxylated disecondary butylphenol (9EO). The emulsifiable concentrate of claim 17 wherein the nonionic surfactant is o0 selected from the group consisting of primary, secondary, and tertiary aliphatic alcohol ethoxylates.

26. The emulsifiable concentrate according to claim 25 wherein the alcohol exothylate is a secondary aliphatic alcohol ethoxylate.

27. The emulsifiable concentrate of claim 17, wherein the nonionic surfactant is an ethoxylated trimethyl nonanol.

28. The emulsifiable concentrate of claim 17, wherein the nonionic surfactant is a polysiloxane or an alkoxylated polysiloxane.

29. The emulsifiable concentrate according to claim 17, wherein the organophosphorous insecticide has a melting point of less than about 110 0 C.

30. The emulsifiable concentrate according to claim 17, wherein the organophosphorous insecticide has a melting point of less than about 90 0 C.

31. The emulsifiable concentrate according to claim 17, wherein said acid composition comprises from 30 to 40 weight percent alkoxylate rosin acid.

32. The emulsifiable concentrate according to claim 17, wherein said acid composition comprises from about 60 to about 70 weight percent fatty acids.

33. The emulsifiable concentrate according to claim 17, wherein the rosin acids and fatty acids have an average molar addition of from about 9 to about 16 alkoxy moieties per molecule of acid.

34. An organophosphorous insecticidal emulsifiable concentrate according to claim 17, substantially as hereinbefore described with reference to any one of the examples. A method of preparing agrochemical emulsifiable concentrates comprising the steps of: i) blending I.doc:mrr 6' 44 a) from about 10 to about 60 percent by weight of a water-insoluble pesticide having a melting point of less than about 120 0 C; b) from about 20 to about 60 percent by weight of an alkoxylated acid composition wherein said acid composition comprises: i) from greater than about 25 to about 60 percent by weight alkoxylated rosin acids; and ii) from about 40 to less than about 75 percent by weight alkoxylated fatty acids wherein the rosin acids and fatty acids have an average molar addition of from about 6 to about 20 alkoxy moieties per molecule of acid; the weight percents of the rosin and fatty lo acids being based on the total weight of said alkoxylated acids; and c) from about 15 to about 45 percent by weight of nonionic surfactant; wherein the weight percents are based on the total weight of the emulsifiable concentrate except where indicated; ii) heating said nonionic surfactant to above the melting point either prior to, during, or after the blending; and iii) cooling the emulsion concentrate so formed to ambient temperature.

36. The method according to claim 35, wherein the water-soluble pesticide has a melting point of less than about 110°C.

37. The method according to claim 35, wherein the water-soluble pesticide has a melting point of less than about

38. The method according to claim 35, wherein said acid composition comprises from 30 to 40 weight percent alkoxylate rosin acid.

39. The method according to claim 35, wherein said acid composition comprises from about 60 to about 70 weight percent fatty acids.

40. The method according to claim 35, wherein the rosin acids and fatty acids have an average molar addition of from about 9 to about 16 alkoxy moieties per molecule of acid.

41. A method of preparing an agrochemical emulsifiable concentrate, said method substantially as hereinbefore described with reference to any one of the examples.

42. An agrochemical emulsifiable concentrate prepared according to the method of any one of claims 35 to 41.

43. A method of preparing organophosphorous insecticidal emulsifiable oT ncentrates comprising the steps of: Si) blending Zz 'OFV\ DayLib\LIBZZ05003.doc:rr i .0 0 i' a) from about 10 to about 60 percent by weight of an organophosphorous insecticide having a melting point of less than about 1200C; b) from about 20 to about 60 percent by weight of an alkoxylated acid composition wherein said acid composition comprises: i) from greater than about 25 to about 60 percent by weight alkoxylated rosin acids; and ii) from about 40 to less than about 75 percent by weight alkoxylated fatty acids wherein the rosin acids and fatty acids have an average molar addition of from about 6 to about 20 alkoxy moieties per molecule of acid; the weight percents of the rosin o0 and fatty acids being based on the total weight of said alkoxylated acids; and c) from about 15 to about 45 percent by weight of nonionic surfactant; wherein the weight percents are based on the total weight of the emulsifiable concentrate except where indicated; ii) heating said nonionic surfactant to above the melting point either prior to, during, or after the blending; and iii) cooling the emulsifiable concentrate so formed to ambient temperature.

44. A method of preparing organophosphorous insecticidal emulsion concentrates consisting essentially of the steps of: i) melting from about 10 to about 60 percent by weight of an organophosphorous insecticide having a melting point of less than about 120 0 C; ii) blending the molten insecticide with from about 20 to about 60 percent by weight of a water-soluble alkoxylated acid composition wherein said acid composition comprises: a) from greater than about 25 to about 60 percent by weight alkoxylated rosin acids; and b) from about 40 to less than about 75 percent by weight alkoxylated fatty acids wherein the rosin acids and fatty acids have an average molar addition of from about 6 to about 20 alkoxy moieties per molecule of acid; the weight percents of the rosin and fatty acids being based on the total weight of said alkoxylated acids; and iii) from about 15 to about 45 percent by weight of nonionic surfactans other than said alkoxylated rosin and alokoxylated fatty acids wherein said concentrate is essentially free of volatile organic compounds; and wherein the weight percents are based on the Stotal weight of the emulsion concentrate except wherein indicated. 7 45. The method according to claim 43 or 44, wherein the organophosphorous iOsecticide has a melting point of less than about 110 0 C. [I:\DayLib\LIBZZ]05003.doc:mrr I0 46

46. The method according to claim 43 or 44, wherein the organophosphorous insecticide has a melting point of less than about 90 0 C.

47. The method according to claim 43 or 44wherein said acid composition comprises from 30 to 40 weight percent alkoxylated rosin acid.

48. The method according to claim 43 or 44, wherein said acid composition comprises from about 60 to about 70 weight percent fatty acids.

49. The method according to claim 43 or 44, wherein the rosin acids and fatty acids have an average molar addition of from about 9 to about 16 alkoxy moieties per molecule of acid.

50. A method of preparing an organophospho-rous insecticidal emulsifiable concentrate, said method substantially as hereinbefore described with reference to any one of the examples.

51. An organophosphorous insecticidal emulsifiable concentrate prepared according to the method of any one of claims 43 to

52. A method of controlling insects which comprises subjecting them to an insecticidally effective amount of a composition.comprising the emulsifiable concentrate of any one of claims 17 to 34 and 51.

53. An organophosphorous insecticidal emulsifiable concentrate according to any one of claims 17 to 34 and 51 when used for controlling insects.

54. Use of an organophosphorous insecticidal emulsifiable concentrate according to any one of claims 17 to 34 and 51 in the preparation of a composition for controlling insects. An insecticidal composition comprising a concentrate according to any one of claims 17 to 34 and 51 together with-at least one diluent or carrier.

56. The insecticidal composition according to claim 55, further comprising at least one agent selected from the group consisting of anti-fieezing agents, anti-foam agents, compatibility agents, oxidation protectants, U.V. protectants, bactericides and pH buffering agents.

57. An agrochemical composition comprising a concentrate according to any one of claims 1 to 16 and 42 together with at least one diluent or carrier. 'Lib\LIBZZ]05003.doc:mnr 47

58. The agrochemical composition according to claim 57, further comprising at least one agent selected from the group consisting of anti-freezing agents, anti-foam agents, compatibility agents, oxidation protectants, U.V. protectants, bactericides and pH buffering agents. Dated 5 July, 2002 Aquatrols Holding Co., Inc. Patent Attorneys for the Applicant/Nominated Person SPRUSON FERGUSON