[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

AU7394394A - 3-hydroxyquinuclidin-3-ylphenylquinolines as squalene synthase inhibitors - Google Patents

3-hydroxyquinuclidin-3-ylphenylquinolines as squalene synthase inhibitors

Info

Publication number
AU7394394A
AU7394394A AU73943/94A AU7394394A AU7394394A AU 7394394 A AU7394394 A AU 7394394A AU 73943/94 A AU73943/94 A AU 73943/94A AU 7394394 A AU7394394 A AU 7394394A AU 7394394 A AU7394394 A AU 7394394A
Authority
AU
Australia
Prior art keywords
ylphenylquinolines
hydroxyquinuclidin
synthase inhibitors
squalene synthase
squalene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU73943/94A
Inventor
Robert D. Groneberg
Martin P. Maguire
Robert L Morris
Kent Neuenschwander
Anthony C. Scotese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Rhone Poulenc Rorer Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/959,898 external-priority patent/US5385912A/en
Application filed by Rhone Poulenc Rorer Pharmaceuticals Inc filed Critical Rhone Poulenc Rorer Pharmaceuticals Inc
Publication of AU7394394A publication Critical patent/AU7394394A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU73943/94A 1992-10-13 1994-05-12 3-hydroxyquinuclidin-3-ylphenylquinolines as squalene synthase inhibitors Abandoned AU7394394A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US959898 1992-10-13
US07/959,898 US5385912A (en) 1991-03-08 1992-10-13 Multicyclic tertiary amine polyaromatic squalene synthase inhibitors
PCT/US1994/005451 WO1995031458A1 (en) 1992-10-13 1994-05-12 3-hydroxyquinuclidin-3-ylphenylquinolines as squalene synthase inhibitors

Publications (1)

Publication Number Publication Date
AU7394394A true AU7394394A (en) 1995-12-05

Family

ID=25502558

Family Applications (1)

Application Number Title Priority Date Filing Date
AU73943/94A Abandoned AU7394394A (en) 1992-10-13 1994-05-12 3-hydroxyquinuclidin-3-ylphenylquinolines as squalene synthase inhibitors

Country Status (2)

Country Link
AU (1) AU7394394A (en)
WO (1) WO1995031458A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1217001T3 (en) 1999-09-28 2006-03-20 Eisai Co Ltd Quinuclidine compounds and drugs containing them as the active ingredient
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
US7655657B2 (en) 2003-12-22 2010-02-02 Abbott Laboratories Fused bicycloheterocycle substituted quinuclidine derivatives
US7160876B2 (en) * 2003-12-22 2007-01-09 Abbott Laboratories Fused bicycloheterocycle substituted quinuclidine derivatives
WO2006065233A1 (en) * 2004-12-10 2006-06-22 Abbott Laboratories Fused bicycloheterocycle substituted quinuclidine derivatives
AR049401A1 (en) 2004-06-18 2006-07-26 Novartis Ag AZA-BICICLONONANS
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203989A (en) * 1979-04-30 1980-05-20 G. D. Searle & Co. Anti-diarrheal diaryl-(1-azabicyclo(2.2.2)octan-2-yl)-alkanols and related compounds
IT1130997B (en) * 1980-03-19 1986-06-18 D & D Srl PHINOXYCARBOXYLIC ACID ESTERS AND KINUCLEIDIN DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS

Also Published As

Publication number Publication date
WO1995031458A1 (en) 1995-11-23

Similar Documents

Publication Publication Date Title
AU1301697A (en) Tyrosin-derivate as alpha-v-integrin inhibitors
AU5533094A (en) Enzyme inhibitors
EP0818448B8 (en) Cycloalkano-pyridine as CETP inhibitors
IL108075A0 (en) Enzyme inhibitors
AU4251993A (en) Substituted 4-aza-5A-androstan-ones as 5A-reductase inhibitors
AU3901393A (en) Biphenylylquinuclidine derivatives as squalene synthase inhibitors
AU5708894A (en) Quinuclidine derivatives as squalene synthase inhibitors
AU640520B2 (en) Novel squalene synthetase inhibitors
AU7749394A (en) Methods for inhibiting uterine fibrosis
AU3165493A (en) Quinuclidine derivatives as squalene synthase inhibitors
AU7394394A (en) 3-hydroxyquinuclidin-3-ylphenylquinolines as squalene synthase inhibitors
AU6571594A (en) Thioindole pyperidinyl derivatives used as antalgics
AU4067795A (en) Squalene synthetase inhibitors
AU7398794A (en) 7-substituted-delta4-6-azasteroid derivatives as 5alpha-reductase inhibitors
AU1797392A (en) Pla2 inhibitors
AU6855594A (en) 9-deazahypoxanthines as pnp inhibitors
AU664685B3 (en) Deodoriser
AU6049796A (en) Lysyloxidase inhibitors
ZA934970B (en) Enzyme inhibitors
AU3900593A (en) Amines as inhibitors of squalene synthase
AU6413594A (en) Substituted 3-phenanthridinone derivatives as 5alpha-reductase inhibitors
AU8133294A (en) 7beta -substituted-4-aza-5alpha-cholestan-3-ones as selective 5alpha-reductase 1 inhibitors
AU8059894A (en) Rooting inhibitors
AU6831994A (en) Aliphatic amino bis-aryl squalene synthase inhibitors
AU5708694A (en) Quinuclidine derivatives as squalene synthase inhibitors