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AU6924687A - Process for the preparation of encainide - Google Patents

Process for the preparation of encainide

Info

Publication number
AU6924687A
AU6924687A AU69246/87A AU6924687A AU6924687A AU 6924687 A AU6924687 A AU 6924687A AU 69246/87 A AU69246/87 A AU 69246/87A AU 6924687 A AU6924687 A AU 6924687A AU 6924687 A AU6924687 A AU 6924687A
Authority
AU
Australia
Prior art keywords
encainide
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU69246/87A
Other versions
AU597939B2 (en
Inventor
John L. Dillon
Richard H. Spector
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of AU6924687A publication Critical patent/AU6924687A/en
Application granted granted Critical
Publication of AU597939B2 publication Critical patent/AU597939B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02—Preparation by ring-closure or hydrogenation

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AU69246/87A 1986-02-25 1987-02-25 Process for the preparation of encainide Ceased AU597939B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/833,295 US4675409A (en) 1986-02-25 1986-02-25 Process for the preparation of encainide
US833295 1986-02-25

Publications (2)

Publication Number Publication Date
AU6924687A true AU6924687A (en) 1987-08-27
AU597939B2 AU597939B2 (en) 1990-06-14

Family

ID=25264016

Family Applications (1)

Application Number Title Priority Date Filing Date
AU69246/87A Ceased AU597939B2 (en) 1986-02-25 1987-02-25 Process for the preparation of encainide

Country Status (23)

Country Link
US (1) US4675409A (en)
JP (1) JPS62240659A (en)
KR (1) KR900001203B1 (en)
AT (1) AT394716B (en)
AU (1) AU597939B2 (en)
BE (1) BE1000112A5 (en)
CA (1) CA1291483C (en)
CH (1) CH671223A5 (en)
DE (1) DE3705664A1 (en)
DK (1) DK94487A (en)
ES (2) ES2002637A6 (en)
FI (1) FI85853C (en)
FR (1) FR2595353B1 (en)
GB (1) GB2187189B (en)
GR (1) GR870281B (en)
HU (1) HU196960B (en)
IL (1) IL81657A0 (en)
IT (1) IT1203501B (en)
LU (1) LU86785A1 (en)
NL (1) NL8700452A (en)
PT (1) PT84348B (en)
SE (1) SE464301B (en)
ZA (1) ZA871334B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800226A (en) * 1986-02-25 1989-01-24 Bristol-Myers Company Process intermediate for the preparation of encainide
JP2009516699A (en) * 2005-11-17 2009-04-23 ノバルティス アクチエンゲゼルシャフト Benzenesulfonates and their use as intermediates for the synthesis of 2- [2- (1-alkyl-2-piperidyl) ethyl] cinnamanilide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931195A (en) * 1971-03-03 1976-01-06 Mead Johnson & Company Substituted piperidines
CA961038A (en) * 1971-03-03 1975-01-14 Joseph L. Minielli Substituted piperidines
US4000143A (en) * 1971-03-03 1976-12-28 Mead Johnson & Company Substituted piperidines
US4064254A (en) * 1971-03-03 1977-12-20 Mead Johnson & Company Substituted piperidines therapeutic process and compositions
US4394507A (en) * 1981-12-14 1983-07-19 Mead Johnson & Company Process for production of encainide

Also Published As

Publication number Publication date
GB8703882D0 (en) 1987-03-25
DE3705664A1 (en) 1987-08-27
ES2007062A6 (en) 1989-06-01
GB2187189A (en) 1987-09-03
KR870007887A (en) 1987-09-22
SE8700776D0 (en) 1987-02-24
SE464301B (en) 1991-04-08
NL8700452A (en) 1987-09-16
DK94487D0 (en) 1987-02-24
FI85853C (en) 1992-06-10
AT394716B (en) 1992-06-10
FR2595353A1 (en) 1987-09-11
GR870281B (en) 1987-06-30
GB2187189B (en) 1990-01-10
IL81657A0 (en) 1987-09-16
FI870767A (en) 1987-08-26
KR900001203B1 (en) 1990-02-28
ES2002637A6 (en) 1988-09-01
SE8700776L (en) 1987-08-26
FI85853B (en) 1992-02-28
DE3705664C2 (en) 1989-09-28
CA1291483C (en) 1991-10-29
LU86785A1 (en) 1987-09-15
FR2595353B1 (en) 1990-11-30
PT84348B (en) 1989-09-14
PT84348A (en) 1987-03-01
DK94487A (en) 1987-08-26
JPS62240659A (en) 1987-10-21
CH671223A5 (en) 1989-08-15
HU196960B (en) 1989-02-28
HUT43563A (en) 1987-11-30
ATA41287A (en) 1991-11-15
ZA871334B (en) 1987-10-28
IT1203501B (en) 1989-02-15
IT8719475A0 (en) 1987-02-24
BE1000112A5 (en) 1988-03-29
FI870767A0 (en) 1987-02-23
AU597939B2 (en) 1990-06-14
US4675409A (en) 1987-06-23

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