AU5893796A - Modification of polypeptides - Google Patents
Modification of polypeptidesInfo
- Publication number
- AU5893796A AU5893796A AU58937/96A AU5893796A AU5893796A AU 5893796 A AU5893796 A AU 5893796A AU 58937/96 A AU58937/96 A AU 58937/96A AU 5893796 A AU5893796 A AU 5893796A AU 5893796 A AU5893796 A AU 5893796A
- Authority
- AU
- Australia
- Prior art keywords
- polypeptides
- modification
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/18—Introducing halogen atoms or halogen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Birds (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK63895 | 1995-06-07 | ||
DK638/95 | 1995-06-07 | ||
PCT/DK1996/000250 WO1996040792A1 (en) | 1995-06-07 | 1996-06-07 | Modification of polypeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
AU5893796A true AU5893796A (en) | 1996-12-30 |
Family
ID=8095855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU58937/96A Abandoned AU5893796A (en) | 1995-06-07 | 1996-06-07 | Modification of polypeptides |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU5893796A (en) |
WO (1) | WO1996040792A1 (en) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6030933A (en) * | 1995-12-29 | 2000-02-29 | The Procter & Gamble Company | Detergent compositions comprising immobilized enzymes |
FI965181A (en) * | 1996-12-20 | 1998-06-21 | Map Medical Technologies Oy | Polyalcohol peptide derivatives |
US6416756B1 (en) | 1997-01-10 | 2002-07-09 | Novozymes A/S | Modified protease having 5 to 13 covalently coupled polymeric molecules for skin care |
CN1253585A (en) * | 1997-01-10 | 2000-05-17 | 诺沃挪第克公司 | Coupled enzyme for skin care |
CZ293666B6 (en) * | 1997-08-14 | 2004-06-16 | Aventis Pharmaceuticals Inc. | Pharmaceutical composition with enhanced bioavailability of antihistaminic and use thereof |
US6908757B1 (en) | 1998-03-26 | 2005-06-21 | The Procter & Gamble Company | Serine protease variants having amino acid deletions and substitutions |
US6495136B1 (en) | 1998-03-26 | 2002-12-17 | The Procter & Gamble Company | Proteases having modified amino acid sequences conjugated to addition moieties |
JP2002507426A (en) | 1998-03-26 | 2002-03-12 | ザ、プロクター、エンド、ギャンブル、カンパニー | Serine protease variants with amino acid substitutions |
EP1088059B1 (en) * | 1998-06-23 | 2004-09-15 | Novozymes A/S | A polypeptide-polymer conjugate |
US6638526B1 (en) | 1998-06-23 | 2003-10-28 | Novozymes A/S | Polypeptides conjugated to copolymers of ethylene oxide and propylene oxide to reduce allergenicity |
KR20010079542A (en) * | 1998-07-17 | 2001-08-22 | 피아 스타르 | A polypeptide-polymer conjugate with improved wash performance |
JP2002527059A (en) * | 1998-10-13 | 2002-08-27 | ノボザイムス アクティーゼルスカブ | Modified polypeptides with reduced immune response |
US6461849B1 (en) | 1998-10-13 | 2002-10-08 | Novozymes, A/S | Modified polypeptide |
WO2001007484A2 (en) | 1999-07-22 | 2001-02-01 | The Procter & Gamble Company | Protease conjugates having sterically protected clip sites |
CN1373802A (en) | 1999-07-22 | 2002-10-09 | 宝洁公司 | Subtilisin protease variants having amino acid deletions and substitutions in defined epitope regions |
US6946128B1 (en) | 1999-07-22 | 2005-09-20 | The Procter & Gamble Company | Protease conjugates having sterically protected epitope regions |
BR0012660A (en) | 1999-07-22 | 2002-04-09 | Procter & Gamble | Protease variant of subtilisin type; cleaning composition; and personal care composition |
US6992174B2 (en) | 2001-03-30 | 2006-01-31 | Emd Lexigen Research Center Corp. | Reducing the immunogenicity of fusion proteins |
EP1585817B1 (en) * | 2002-02-20 | 2009-09-02 | The General Hospital Corporation | Conjugates comprising a biodegradable polymer and uses therefor |
AU2005203962C1 (en) | 2004-01-05 | 2012-11-08 | Antisoma Research Limited | Interleukin-12 targeted to oncofoetal fibronectin |
US7714114B2 (en) | 2005-02-16 | 2010-05-11 | Nektar Therapeutics | Conjugates of an EPO moiety and a polymer |
JP5781501B2 (en) | 2009-04-22 | 2015-09-24 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | Antibody fusion protein with modified FcRn binding site |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
DE3440141A1 (en) * | 1984-11-02 | 1986-05-07 | Heiner Dipl.-Chem. Dr. 8000 München Eckert | Use of bistrichloromethyl carbonate as a proreagent for phosgene |
AU5526690A (en) * | 1989-04-19 | 1990-11-29 | Enzon, Inc. | Active carbonates of polyalkylene oxides for modification of polypeptides |
WO1991001758A1 (en) * | 1989-08-07 | 1991-02-21 | Debiopharm S.A. | Biologically active drug polymer derivatives |
DD287951A5 (en) * | 1989-09-15 | 1991-03-14 | Adw Zi F. Molekularbiologie,De | PROCESS FOR IMMOBILIZING BIOLOGICALLY ACTIVE COMPOUNDS ON POLYOXYALKYLENE GLYCOL AND ITS MONOALKOXY DERIVATIVES |
US5133968A (en) * | 1990-08-20 | 1992-07-28 | Kanebo, Ltd. | Modified protease, method of producing the same and cosmetic products containing the modified protease |
FR2687681B1 (en) * | 1992-02-20 | 1995-10-13 | Transgene Sa | POLYETHYLENEGLYCOL-HIRUDINE CONJUGATES, THEIR PREPARATION PROCESS AND THEIR USE FOR THE TREATMENT OF THROMBOSES. |
AU5006993A (en) * | 1992-08-21 | 1994-03-15 | Enzon, Inc. | Novel attachment of polyalkylene oxides to bio-effecting substances |
US5349001A (en) * | 1993-01-19 | 1994-09-20 | Enzon, Inc. | Cyclic imide thione activated polyalkylene oxides |
DE69309452T2 (en) * | 1993-06-29 | 1997-11-06 | Heylecina S A | Production of activated carbamates of polyalkylene glycol and their use |
US5650234A (en) * | 1994-09-09 | 1997-07-22 | Surface Engineering Technologies, Division Of Innerdyne, Inc. | Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces |
-
1996
- 1996-06-07 WO PCT/DK1996/000250 patent/WO1996040792A1/en active Application Filing
- 1996-06-07 AU AU58937/96A patent/AU5893796A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1996040792A1 (en) | 1996-12-19 |
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