[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

AU5893796A - Modification of polypeptides - Google Patents

Modification of polypeptides

Info

Publication number
AU5893796A
AU5893796A AU58937/96A AU5893796A AU5893796A AU 5893796 A AU5893796 A AU 5893796A AU 58937/96 A AU58937/96 A AU 58937/96A AU 5893796 A AU5893796 A AU 5893796A AU 5893796 A AU5893796 A AU 5893796A
Authority
AU
Australia
Prior art keywords
polypeptides
modification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU58937/96A
Inventor
Thomas Christian Beck
Arne Agerlin Olsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of AU5893796A publication Critical patent/AU5893796A/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/18Introducing halogen atoms or halogen-containing groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/30Introducing nitrogen atoms or nitrogen-containing groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32Polymers modified by chemical after-treatment
    • C08G65/329Polymers modified by chemical after-treatment with organic compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU58937/96A 1995-06-07 1996-06-07 Modification of polypeptides Abandoned AU5893796A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK63895 1995-06-07
DK638/95 1995-06-07
PCT/DK1996/000250 WO1996040792A1 (en) 1995-06-07 1996-06-07 Modification of polypeptides

Publications (1)

Publication Number Publication Date
AU5893796A true AU5893796A (en) 1996-12-30

Family

ID=8095855

Family Applications (1)

Application Number Title Priority Date Filing Date
AU58937/96A Abandoned AU5893796A (en) 1995-06-07 1996-06-07 Modification of polypeptides

Country Status (2)

Country Link
AU (1) AU5893796A (en)
WO (1) WO1996040792A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6030933A (en) * 1995-12-29 2000-02-29 The Procter & Gamble Company Detergent compositions comprising immobilized enzymes
FI965181A (en) * 1996-12-20 1998-06-21 Map Medical Technologies Oy Polyalcohol peptide derivatives
US6416756B1 (en) 1997-01-10 2002-07-09 Novozymes A/S Modified protease having 5 to 13 covalently coupled polymeric molecules for skin care
CN1253585A (en) * 1997-01-10 2000-05-17 诺沃挪第克公司 Coupled enzyme for skin care
CZ293666B6 (en) * 1997-08-14 2004-06-16 Aventis Pharmaceuticals Inc. Pharmaceutical composition with enhanced bioavailability of antihistaminic and use thereof
US6908757B1 (en) 1998-03-26 2005-06-21 The Procter & Gamble Company Serine protease variants having amino acid deletions and substitutions
US6495136B1 (en) 1998-03-26 2002-12-17 The Procter & Gamble Company Proteases having modified amino acid sequences conjugated to addition moieties
JP2002507426A (en) 1998-03-26 2002-03-12 ザ、プロクター、エンド、ギャンブル、カンパニー Serine protease variants with amino acid substitutions
EP1088059B1 (en) * 1998-06-23 2004-09-15 Novozymes A/S A polypeptide-polymer conjugate
US6638526B1 (en) 1998-06-23 2003-10-28 Novozymes A/S Polypeptides conjugated to copolymers of ethylene oxide and propylene oxide to reduce allergenicity
KR20010079542A (en) * 1998-07-17 2001-08-22 피아 스타르 A polypeptide-polymer conjugate with improved wash performance
JP2002527059A (en) * 1998-10-13 2002-08-27 ノボザイムス アクティーゼルスカブ Modified polypeptides with reduced immune response
US6461849B1 (en) 1998-10-13 2002-10-08 Novozymes, A/S Modified polypeptide
WO2001007484A2 (en) 1999-07-22 2001-02-01 The Procter & Gamble Company Protease conjugates having sterically protected clip sites
CN1373802A (en) 1999-07-22 2002-10-09 宝洁公司 Subtilisin protease variants having amino acid deletions and substitutions in defined epitope regions
US6946128B1 (en) 1999-07-22 2005-09-20 The Procter & Gamble Company Protease conjugates having sterically protected epitope regions
BR0012660A (en) 1999-07-22 2002-04-09 Procter & Gamble Protease variant of subtilisin type; cleaning composition; and personal care composition
US6992174B2 (en) 2001-03-30 2006-01-31 Emd Lexigen Research Center Corp. Reducing the immunogenicity of fusion proteins
EP1585817B1 (en) * 2002-02-20 2009-09-02 The General Hospital Corporation Conjugates comprising a biodegradable polymer and uses therefor
AU2005203962C1 (en) 2004-01-05 2012-11-08 Antisoma Research Limited Interleukin-12 targeted to oncofoetal fibronectin
US7714114B2 (en) 2005-02-16 2010-05-11 Nektar Therapeutics Conjugates of an EPO moiety and a polymer
JP5781501B2 (en) 2009-04-22 2015-09-24 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung Antibody fusion protein with modified FcRn binding site

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
DE3440141A1 (en) * 1984-11-02 1986-05-07 Heiner Dipl.-Chem. Dr. 8000 München Eckert Use of bistrichloromethyl carbonate as a proreagent for phosgene
AU5526690A (en) * 1989-04-19 1990-11-29 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
WO1991001758A1 (en) * 1989-08-07 1991-02-21 Debiopharm S.A. Biologically active drug polymer derivatives
DD287951A5 (en) * 1989-09-15 1991-03-14 Adw Zi F. Molekularbiologie,De PROCESS FOR IMMOBILIZING BIOLOGICALLY ACTIVE COMPOUNDS ON POLYOXYALKYLENE GLYCOL AND ITS MONOALKOXY DERIVATIVES
US5133968A (en) * 1990-08-20 1992-07-28 Kanebo, Ltd. Modified protease, method of producing the same and cosmetic products containing the modified protease
FR2687681B1 (en) * 1992-02-20 1995-10-13 Transgene Sa POLYETHYLENEGLYCOL-HIRUDINE CONJUGATES, THEIR PREPARATION PROCESS AND THEIR USE FOR THE TREATMENT OF THROMBOSES.
AU5006993A (en) * 1992-08-21 1994-03-15 Enzon, Inc. Novel attachment of polyalkylene oxides to bio-effecting substances
US5349001A (en) * 1993-01-19 1994-09-20 Enzon, Inc. Cyclic imide thione activated polyalkylene oxides
DE69309452T2 (en) * 1993-06-29 1997-11-06 Heylecina S A Production of activated carbamates of polyalkylene glycol and their use
US5650234A (en) * 1994-09-09 1997-07-22 Surface Engineering Technologies, Division Of Innerdyne, Inc. Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces

Also Published As

Publication number Publication date
WO1996040792A1 (en) 1996-12-19

Similar Documents

Publication Publication Date Title
AU5893696A (en) Modification of polypeptides
AU7203496A (en) Novel peptides
AU5235796A (en) o-hydroxyphenyl-s-triazines
AU4780896A (en) Core-board
AU5893796A (en) Modification of polypeptides
AU1030997A (en) Taphane
AU4996696A (en) 2-benzyl-3-arylbenzothiophenes
AU5147496A (en) Fucopeptides
AU4427296A (en) Novel peptide
AU4394396A (en) Modified peptides
AU4224096A (en) Use of phenylcyclohexylcarboxamides
AU5593896A (en) Benzisothiazolyl-substituted aminomethylchromans
AU5500196A (en) Anti-transpirants
AU4382896A (en) Acetylimidazobenzodiazepines
AU7520396A (en) Abl-interactor protein
AU4877196A (en) Derivatives of 3-pyrrolidylidene-2-one-cephalosporines
AU5108596A (en) Morphine-3-esters
AU5284296A (en) Immune-evading proteins
AU6890696A (en) Peptide derivatives
AU5013796A (en) Wireclamp
AU6153396A (en) E6ap-binding proteins
AU6890596A (en) Peptide derivatives
AU5107096A (en) Haemodialyser
AU5161296A (en) Anti-haemorrhagic peptides
AU4569496A (en) Tetralinyl- and indanyl-ethylamides