AU5667186A - Nucleic acid sequences attached to materials sensitive to magnetic fields, and methods of assay and apparatus using such attached sequences - Google Patents
Nucleic acid sequences attached to materials sensitive to magnetic fields, and methods of assay and apparatus using such attached sequencesInfo
- Publication number
- AU5667186A AU5667186A AU56671/86A AU5667186A AU5667186A AU 5667186 A AU5667186 A AU 5667186A AU 56671/86 A AU56671/86 A AU 56671/86A AU 5667186 A AU5667186 A AU 5667186A AU 5667186 A AU5667186 A AU 5667186A
- Authority
- AU
- Australia
- Prior art keywords
- attached
- sequences
- assay
- nucleic acid
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
- C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8507706 | 1985-03-25 | ||
GB858507706A GB8507706D0 (en) | 1985-03-25 | 1985-03-25 | Magnetic nucleic acid sequences |
Publications (1)
Publication Number | Publication Date |
---|---|
AU5667186A true AU5667186A (en) | 1986-10-23 |
Family
ID=10576594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU56671/86A Abandoned AU5667186A (en) | 1985-03-25 | 1986-03-25 | Nucleic acid sequences attached to materials sensitive to magnetic fields, and methods of assay and apparatus using such attached sequences |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0216844A1 (en) |
AU (1) | AU5667186A (en) |
GB (1) | GB8507706D0 (en) |
WO (1) | WO1986005815A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU640626B2 (en) * | 1988-11-21 | 1993-09-02 | Dynal As | Nucleic acid probes |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4948882A (en) * | 1983-02-22 | 1990-08-14 | Syngene, Inc. | Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis |
US4554088A (en) * | 1983-05-12 | 1985-11-19 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
US5770459A (en) * | 1986-04-30 | 1998-06-23 | Igen International, Inc. | Methods and apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence detection |
ZA877772B (en) * | 1986-10-23 | 1988-04-20 | Amoco Corporation | Target and background capture methods and apparatus for affinity assays |
IL85551A0 (en) * | 1987-04-01 | 1988-08-31 | Miles Inc | Rapid hybridization assay and reagent system used therein |
US6881589B1 (en) | 1987-04-30 | 2005-04-19 | Bioveris Corporation | Electrochemiluminescent localizable complexes for assay compositions |
US5935779A (en) * | 1988-11-03 | 1999-08-10 | Igen International Inc. | Methods for improved particle electrochemiluminescence assay |
US6013531A (en) * | 1987-10-26 | 2000-01-11 | Dade International Inc. | Method to use fluorescent magnetic polymer particles as markers in an immunoassay |
JP2736467B2 (en) * | 1987-10-26 | 1998-04-02 | デイド、インターナショナル、インコーポレイテッド | Manufacturing method of magnetically responsive polymer particles and its application |
AU2735988A (en) * | 1987-12-21 | 1989-07-13 | Amoco Corporation | Target and background capture methods with amplification for affinity assays |
ATE114726T1 (en) * | 1988-05-10 | 1994-12-15 | Du Pont | METHODS FOR THE RAPID DETECTION OF NUCLEIC ACIDS. |
NO165894C (en) * | 1988-05-24 | 1991-04-24 | Gunnar Paulsen | METHOD OF ANALYSIS OF GENES. |
WO1990002205A1 (en) * | 1988-08-25 | 1990-03-08 | Angenics, Inc. | Detection of nucleic acid sequences using particle agglutination |
US5705402A (en) * | 1988-11-03 | 1998-01-06 | Igen International, Inc. | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets |
US5962218A (en) * | 1988-11-03 | 1999-10-05 | Igen International Inc. | Methods and apparatus for improved luminescence assays |
US5746974A (en) * | 1988-11-03 | 1998-05-05 | Igen International, Inc. | Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection |
US5779976A (en) * | 1988-11-03 | 1998-07-14 | Igen International, Inc. | Apparatus for improved luminescence assays |
US5798083A (en) * | 1988-11-03 | 1998-08-25 | Igen International, Inc. | Apparatus for improved luminescence assays using particle concentration and chemiluminescence detection |
DK175170B1 (en) * | 1988-11-29 | 2004-06-21 | Sangtec Molecular Diagnostics | Method and Reagent Combination to Determine Nucleotide Sequences |
KR920700360A (en) * | 1989-03-22 | 1992-02-19 | 하리크 프리드리히 | Sliding bearing |
US5232829A (en) * | 1989-09-29 | 1993-08-03 | Hoffmann-La Roche Inc. | Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes |
FR2654836B1 (en) * | 1989-11-17 | 1994-01-28 | Biotrol Sa Laboratoires | APPARATUS FOR AUTOMATICALLY PERFORMING MULTIPLE SUCCESSIVE IMMUNODAYS OF AT LEAST ONE BIOLOGICAL SUBSTANCE IN A PLURALITY OF BIOLOGICAL SAMPLES, PROCESS AND REAGENT USING THE SAME. |
CA2031659A1 (en) * | 1990-01-26 | 1991-07-27 | John B. Findlay | Water-insoluble reagent, nucleic acid probe, test kit and diagnostic and purification methods |
EP0523171A1 (en) * | 1990-04-06 | 1993-01-20 | Syngene, Inc. | Process and composition for performing dna assays |
AU8951191A (en) * | 1990-10-29 | 1992-05-26 | Dekalb Plant Genetics | Isolation of biological materials using magnetic particles |
US5665582A (en) * | 1990-10-29 | 1997-09-09 | Dekalb Genetics Corp. | Isolation of biological materials |
IL100866A (en) * | 1991-02-06 | 1995-10-31 | Igen Inc | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets |
IL100867A (en) * | 1991-02-06 | 1995-12-08 | Igen Inc | Method and apparatus for improved luminescence assays |
ZA92803B (en) | 1991-02-06 | 1992-11-25 | Igen Inc | Method and apparatus for magnetic microparticulate based luminescene asay including plurality of magnets |
CA2112675C (en) * | 1991-07-10 | 2007-03-20 | Richard J. Massey | Methods and apparatus for improved luminescence assays using particle concentration and chemiluminescence detection |
GB9127415D0 (en) * | 1991-12-24 | 1992-02-19 | Swordfish Int Ltd | Solid support bound detection and diagnostic system |
WO1993020234A1 (en) * | 1992-03-31 | 1993-10-14 | E.I. Du Pont De Nemours And Company | A rapid, high capacity nucleic acid based assay |
GB9212164D0 (en) * | 1992-06-09 | 1992-07-22 | Medical Res Council | Preparation of nucleic acids |
US5329461A (en) * | 1992-07-23 | 1994-07-12 | Acrogen, Inc. | Digital analyte detection system |
CA2170264A1 (en) * | 1993-09-10 | 1995-03-16 | Michael W. Konrad | Optical detection of position of oligonucleotides on large dna molecules |
GB9322723D0 (en) * | 1993-11-04 | 1993-12-22 | Tepnel Medical Ltd | Determining nucleic acids |
US6071699A (en) | 1996-06-07 | 2000-06-06 | California Institute Of Technology | Nucleic acid mediated electron transfer |
US5824473A (en) | 1993-12-10 | 1998-10-20 | California Institute Of Technology | Nucleic acid mediated electron transfer |
GB9425138D0 (en) | 1994-12-12 | 1995-02-08 | Dynal As | Isolation of nucleic acid |
WO1996040273A2 (en) * | 1995-06-07 | 1996-12-19 | Schering Aktiengesellschaft | Conjugates of ferrites and oligonucleotides, which bond specifically to certain target structures |
JP2965131B2 (en) * | 1995-07-07 | 1999-10-18 | 東洋紡績株式会社 | Magnetic carrier for nucleic acid binding and nucleic acid isolation method using the same |
US7045285B1 (en) | 1996-11-05 | 2006-05-16 | Clinical Micro Sensors, Inc. | Electronic transfer moieties attached to peptide nucleic acids |
US7014992B1 (en) | 1996-11-05 | 2006-03-21 | Clinical Micro Sensors, Inc. | Conductive oligomers attached to electrodes and nucleoside analogs |
US7393645B2 (en) | 1996-11-05 | 2008-07-01 | Clinical Micro Sensors, Inc. | Compositions for the electronic detection of analytes utilizing monolayers |
US7381525B1 (en) | 1997-03-07 | 2008-06-03 | Clinical Micro Sensors, Inc. | AC/DC voltage apparatus for detection of nucleic acids |
WO1998034114A1 (en) * | 1997-01-30 | 1998-08-06 | Merck Patent Gmbh | Method for the immunological determination of an analyte |
US6013459A (en) | 1997-06-12 | 2000-01-11 | Clinical Micro Sensors, Inc. | Detection of analytes using reorganization energy |
US6682648B1 (en) | 1997-08-12 | 2004-01-27 | University Of Southern California | Electrochemical reporter system for detecting analytical immunoassay and molecular biology procedures |
CA2319170A1 (en) | 1998-01-27 | 1999-07-29 | Clinical Micro Sensors, Inc. | Amplification of nucleic acids with electronic detection |
US6686150B1 (en) | 1998-01-27 | 2004-02-03 | Clinical Micro Sensors, Inc. | Amplification of nucleic acids with electronic detection |
WO1999057313A1 (en) * | 1998-05-04 | 1999-11-11 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Method and device for isolating nucleic acids |
CA2331189A1 (en) | 1998-05-06 | 1999-11-11 | Clinical Micro Sensors, Inc. | Electronic methods for the detection of analytes utilizing monolayers |
CA2327525A1 (en) * | 1998-05-06 | 1999-11-11 | Cynthia Bamdad | Electronic detection of nucleic acids using monolayers |
US6761816B1 (en) | 1998-06-23 | 2004-07-13 | Clinical Micro Systems, Inc. | Printed circuit boards with monolayers and capture ligands |
US6740518B1 (en) | 1998-09-17 | 2004-05-25 | Clinical Micro Sensors, Inc. | Signal detection techniques for the detection of analytes |
WO2000024941A1 (en) | 1998-10-27 | 2000-05-04 | Clinical Micro Sensors, Inc. | Detection of target analytes using particles and electrodes |
AU3487800A (en) * | 1999-02-11 | 2000-08-29 | University Of Southern California | Enzyme-linked immuno-magnetic electrochemical biosensor |
WO2001006016A2 (en) * | 1999-07-20 | 2001-01-25 | Clinical Micro Sensors, Inc. | Amplification of nucleic acids with electronic detection |
ATE417127T1 (en) | 1999-07-26 | 2008-12-15 | Clinical Micro Sensors Inc | NUKELIC ACID SEQUENCE DETERMINATION USING ELECTRONIC DETECTION |
US6875619B2 (en) | 1999-11-12 | 2005-04-05 | Motorola, Inc. | Microfluidic devices comprising biochannels |
FR2805545B1 (en) * | 2000-02-24 | 2002-05-17 | Argene Sa | ELECTROCHEMICAL METHOD FOR DETECTION OF NUCLEIC ACIDS |
US6602400B1 (en) | 2000-06-15 | 2003-08-05 | Motorola, Inc. | Method for enhanced bio-conjugation events |
DE60137652D1 (en) * | 2001-02-16 | 2009-03-26 | Cortex Biochem Inc | MAGNETIC INSULATION AND PURIFICATION OF NUCLEIC ACIDS |
ATE491790T1 (en) | 2001-11-06 | 2011-01-15 | Promega Corp | ISOLATION AND PURIFICATION OF NUCLEIC ACIDS |
WO2005016115A2 (en) | 2003-01-23 | 2005-02-24 | Montana State University | Biosensors utilizing dendrimer-immobilized ligands and their use thereof |
US20050059024A1 (en) | 2003-07-25 | 2005-03-17 | Ambion, Inc. | Methods and compositions for isolating small RNA molecules |
EP1871913A2 (en) | 2005-03-25 | 2008-01-02 | Ambion, Inc. | Methods and compositions for depleting abundant rna transcripts |
EP1877884A4 (en) * | 2005-04-18 | 2009-02-04 | Univ California | A method and apparatus for monitoring biometrical data |
WO2007053191A2 (en) | 2005-06-03 | 2007-05-10 | University Of Texas System | Electrochemistry and electrogenerated chemiluminescence with a single faradaic electrode |
WO2009061941A2 (en) * | 2007-11-06 | 2009-05-14 | Osmetech Molecular Diagnostics | Baseless nucleotide analogues and uses thereof |
CN112538519B (en) * | 2019-09-20 | 2022-09-27 | 华中农业大学 | Method for detecting food-borne pathogenic bacteria by enzymatic low-field nuclear magnetic resonance DNA sensor |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0030087A1 (en) * | 1979-11-13 | 1981-06-10 | Technicon Instruments Company Limited | Immunoassay method and apparatus and kit for carrying out the method |
CA1180647A (en) * | 1981-07-17 | 1985-01-08 | Cavit Akin | Light-emitting polynucleotide hybridization diagnostic method |
CA1220818A (en) * | 1983-05-05 | 1987-04-21 | Hugh A.O. Hill | Assay techniques utilising specific binding agents |
US4554088A (en) * | 1983-05-12 | 1985-11-19 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
EP0149339B1 (en) * | 1983-12-16 | 1989-08-23 | MediSense, Inc. | Assay for nucleic acids |
GB8400070D0 (en) * | 1984-01-04 | 1984-02-08 | Serono Diagnostics Ltd | Magnetic assay reagents |
-
1985
- 1985-03-25 GB GB858507706A patent/GB8507706D0/en active Pending
-
1986
- 1986-03-25 EP EP86901967A patent/EP0216844A1/en not_active Withdrawn
- 1986-03-25 AU AU56671/86A patent/AU5667186A/en not_active Abandoned
- 1986-03-25 WO PCT/GB1986/000174 patent/WO1986005815A1/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU640626B2 (en) * | 1988-11-21 | 1993-09-02 | Dynal As | Nucleic acid probes |
Also Published As
Publication number | Publication date |
---|---|
GB8507706D0 (en) | 1985-05-01 |
WO1986005815A1 (en) | 1986-10-09 |
EP0216844A1 (en) | 1987-04-08 |
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