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AU558331B2 - Solid medicament formulations containing nifedipine, and processes for their preparation - Google Patents

Solid medicament formulations containing nifedipine, and processes for their preparation

Info

Publication number
AU558331B2
AU558331B2 AU75063/81A AU7506381A AU558331B2 AU 558331 B2 AU558331 B2 AU 558331B2 AU 75063/81 A AU75063/81 A AU 75063/81A AU 7506381 A AU7506381 A AU 7506381A AU 558331 B2 AU558331 B2 AU 558331B2
Authority
AU
Australia
Prior art keywords
processes
preparation
formulations containing
solid medicament
medicament formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU75063/81A
Other versions
AU7506381A (en
Inventor
Ahmed Hegasy
Klaus-Dieter Ramsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6111496&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU558331(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU7506381A publication Critical patent/AU7506381A/en
Application granted granted Critical
Publication of AU558331B2 publication Critical patent/AU558331B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
AU75063/81A 1980-09-09 1981-09-08 Solid medicament formulations containing nifedipine, and processes for their preparation Expired AU558331B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE30339196 1980-09-09
DE19803033919 DE3033919A1 (en) 1980-09-09 1980-09-09 SOLID PHARMACEUTICAL PREPARATIONS CONTAINING NIFEDIPINE AND METHOD FOR THE PRODUCTION THEREOF

Publications (2)

Publication Number Publication Date
AU7506381A AU7506381A (en) 1982-03-18
AU558331B2 true AU558331B2 (en) 1987-01-29

Family

ID=6111496

Family Applications (1)

Application Number Title Priority Date Filing Date
AU75063/81A Expired AU558331B2 (en) 1980-09-09 1981-09-08 Solid medicament formulations containing nifedipine, and processes for their preparation

Country Status (20)

Country Link
EP (1) EP0047899B2 (en)
JP (1) JPS5914446B2 (en)
AR (1) AR226377A1 (en)
AT (1) ATE5761T1 (en)
AU (1) AU558331B2 (en)
CA (1) CA1180277A (en)
DD (1) DD201974A5 (en)
DE (2) DE3033919A1 (en)
DK (1) DK154326C (en)
FI (1) FI72648B (en)
GR (1) GR78237B (en)
HU (1) HU184879B (en)
IE (1) IE51549B1 (en)
IL (1) IL63749A (en)
NO (1) NO157368B (en)
NZ (1) NZ198285A (en)
PH (1) PH24097A (en)
PL (1) PL232951A1 (en)
PT (1) PT73603B (en)
ZA (1) ZA816213B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264446A (en) * 1980-09-09 1993-11-23 Bayer Aktiengesellschaft Solid medicament formulations containing nifedipine, and processes for their preparation
JPS5846019A (en) * 1981-09-14 1983-03-17 Kanebo Ltd Nifedipine preparation with prolonged action
DE3222367A1 (en) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Use of 1,4-dihydropyridines in antiarteriosclerotics and preparation thereof
JPS59101423A (en) * 1982-12-02 1984-06-12 Takada Seiyaku Kk Novel solid pharmaceutical preparation of nifedipine
US4529733A (en) * 1983-04-06 1985-07-16 Merrell Dow Pharmaceuticals Inc. Antihypertensive 3-furoyl-1,4-dihydropyridines
DE3318649A1 (en) * 1983-05-21 1984-11-22 Bayer Ag, 5090 Leverkusen TWO-PHASE FORMULATION
NL194389C (en) * 1984-06-14 2002-03-04 Novartis Ag Process for preparing a solid dispersion of a pharmaceutically active agent that has low water solubility in a solid matrix of a water-soluble polyalkylene glycol as a carrier.
IT1178511B (en) * 1984-09-14 1987-09-09 Pharmatec Spa PROCEDURE FOR THE PREPARATION OF A SOLID FORM FOR ORAL USE BASED ON NIFEDIPINE WITH RELEASE
IT1187751B (en) * 1985-10-15 1987-12-23 Eurand Spa PROCEDURE FOR THE PREPARATION OF SOLID FORMULATIONS OF NIFEDIPINE WITH HIGH BIO AVAILABILITY AND WITH PROLONGED EFFECT AND FORMULATIONS SO OBTAINED
US4940556A (en) * 1986-01-30 1990-07-10 Syntex (U.S.A.) Inc. Method of preparing long acting formulation
US5198226A (en) * 1986-01-30 1993-03-30 Syntex (U.S.A.) Inc. Long acting nicardipine hydrochloride formulation
CH673947A5 (en) * 1986-09-23 1990-04-30 Sandoz Ag
JPS6464659A (en) * 1987-09-03 1989-03-10 Kenbi Kogaku Kenkyusho Kk Preparation of safe and effective powder formulation
SE8703881D0 (en) * 1987-10-08 1987-10-08 Haessle Ab NEW PHARMACEUTICAL PREPARATION
DE3814532A1 (en) * 1988-04-29 1989-11-09 Bayer Ag DHP-RETARD-PREPARATION
JPH0298550U (en) * 1989-01-25 1990-08-06
GB8903328D0 (en) * 1989-02-14 1989-04-05 Ethical Pharma Ltd Nifedipine-containing pharmaceutical compositions and process for the preparation thereof
US5271944A (en) * 1991-04-05 1993-12-21 Biofor, Ltd. Pharmacologically enhanced formulations
DE4130173A1 (en) * 1991-09-11 1993-03-18 Bayer Ag PHARMACEUTICAL PREPARATIONS WITH A SPECIAL CRYSTAL MODIFICATION OF 1,4-DIHYDRO-2,6-DIMETHYL-4- (3-NITROPHENYL) -3,5-PYRIDINDICARBONIC ACID ISOPROPYL- (2-METHOXYETHYL) ESTER
GB9200607D0 (en) * 1992-01-13 1992-03-11 Ethical Pharma Ltd Pharmaceutical compositions containing nifedipine and process for the preparation thereof
US6726930B1 (en) 1993-09-09 2004-04-27 Penwest Pharmaceuticals Co. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5773025A (en) * 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US5543099A (en) * 1994-09-29 1996-08-06 Hallmark Pharmaceutical, Inc. Process to manufacture micronized nifedipine granules for sustained release medicaments
WO1996020707A1 (en) * 1994-12-29 1996-07-11 Dr. Rentschler Arzneimittel Gmbh & Co. Pharmaceutical preparations containing nifedipine and process for producing it
JP3220373B2 (en) 1995-11-28 2001-10-22 バイエル薬品株式会社 Long-acting nifedipine preparation
IL123505A (en) * 1996-07-08 2004-12-15 Penwest Pharmaceuticals Compan Sustained release matrix for high-dose insoluble drugs
IT1284604B1 (en) * 1996-09-27 1998-05-21 Roberto Valducci CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION CONTAINING NIFEDIPINE AS THE ACTIVE SUBSTANCE
US6056977A (en) 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
MXPA01005370A (en) 1999-09-30 2004-05-14 Penwest Pharmaceuticals Co Sustained release matrix systems for highly soluble drugs.
EP1741712B1 (en) 2004-07-30 2011-06-15 Torrent Pharmaceuticals Ltd amorphous form of nebivolol hydrochloride and its preparation
DE102004062475A1 (en) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Solid, orally administrable, modified release pharmaceutical dosage forms

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3330727A (en) * 1960-04-19 1967-07-11 Glaxo Lab Ltd Griseofulvin with high specific surface area
US3401221A (en) * 1964-08-25 1968-09-10 Norwich Pharma Co Treatment of urinary tract infection
DE2348334C2 (en) * 1973-09-26 1982-11-11 Boehringer Mannheim Gmbh, 6800 Mannheim New form of preparation of N-4- [2- (5-chloro-2-methoxybenzamido) ethyl] -phenyl-sulfonyl-N'-cyclohexylurea
DE2400819C2 (en) * 1974-01-09 1982-04-22 Bayer Ag, 5090 Leverkusen Process for the production of solid preparations of poorly soluble active pharmaceutical ingredients in extremely fine distribution
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
JPS55129221A (en) * 1979-03-29 1980-10-06 Kaken Pharmaceut Co Ltd Preparation of oral preparation containing hardly soluble medicine
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material

Also Published As

Publication number Publication date
HU184879B (en) 1984-10-29
PL232951A1 (en) 1982-10-11
ZA816213B (en) 1982-09-29
EP0047899B1 (en) 1984-01-04
JPS5914446B2 (en) 1984-04-04
NZ198285A (en) 1984-04-27
EP0047899B2 (en) 1996-02-28
PT73603A (en) 1981-09-01
DK396381A (en) 1982-03-10
NO812879L (en) 1982-03-10
GR78237B (en) 1984-09-26
DK154326B (en) 1988-11-07
FI72648B (en) 1987-03-31
ATE5761T1 (en) 1984-01-15
IL63749A0 (en) 1981-12-31
DE3161838D1 (en) 1984-02-09
PH24097A (en) 1990-03-05
IL63749A (en) 1984-06-29
NO157368B (en) 1987-11-30
AR226377A1 (en) 1982-06-30
CA1180277A (en) 1985-01-02
PT73603B (en) 1982-11-10
EP0047899A1 (en) 1982-03-24
AU7506381A (en) 1982-03-18
DK154326C (en) 1995-03-13
FI812758L (en) 1982-03-10
DD201974A5 (en) 1983-08-24
DE3033919A1 (en) 1982-04-22
IE812075L (en) 1982-03-09
JPS5750913A (en) 1982-03-25
IE51549B1 (en) 1987-01-07

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired