AU521533B2 - 1, 2-benzisoxazolozyacetic acids and related compounds - Google Patents

1, 2-benzisoxazolozyacetic acids and related compounds

Info

Publication number: AU521533B2
Authority: AU; Australia
Prior art keywords: benzisoxazolozyacetic; acids; related compounds; compounds; benzisoxazolozyacetic acids
Prior art date: 1977-11-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

AU41716/78A

Other versions

AU4171678A (en

Inventor

Linda Louise Setescak And Richard Charles Allen Gregory Michael Shutske

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Hoechst AG

Original Assignee

Hoechst AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-11-21

Filing date

1978-11-20

Publication date

1982-04-08

1978-11-20 Application filed by Hoechst AG filed Critical Hoechst AG

1979-05-31 Publication of AU4171678A publication Critical patent/AU4171678A/en

1982-04-08 Application granted granted Critical

1982-04-08 Publication of AU521533B2 publication Critical patent/AU521533B2/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Hematology (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Thiazole And Isothizaole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AU41716/78A 1977-11-21 1978-11-20 1, 2-benzisoxazolozyacetic acids and related compounds Expired AU521533B2 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US85331377A	1977-11-21	1977-11-21
USUS853313		1977-11-21
US94912878A	1978-10-06	1978-10-06
USUS949128		1978-10-06

Publications (2)

Publication Number	Publication Date
AU4171678A AU4171678A (en)	1979-05-31
AU521533B2 true AU521533B2 (en)	1982-04-08

Family

ID=27127134

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU41716/78A Expired AU521533B2 (en)	1977-11-21	1978-11-20	1, 2-benzisoxazolozyacetic acids and related compounds

Country Status (18)

Country	Link
EP (1)	EP0002666B1 (en)
JP (1)	JPS5495563A (en)
AT (1)	AT371811B (en)
AU (1)	AU521533B2 (en)
CA (1)	CA1111853A (en)
DE (1)	DE2861637D1 (en)
DK (1)	DK515978A (en)
EG (1)	EG13533A (en)
ES (3)	ES475100A1 (en)
FI (1)	FI783515A (en)
GR (1)	GR72950B (en)
HU (1)	HU180785B (en)
IE (1)	IE47299B1 (en)
IL (1)	IL55997A0 (en)
IT (1)	IT7829897A0 (en)
NO (1)	NO783908L (en)
NZ (1)	NZ188946A (en)
PT (1)	PT68807A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4337261A (en) *	1980-07-28	1982-06-29	Hoechst-Roussel Pharmaceuticals Inc.	(1,2-Benzisoxazol)phenoxyacetic acids as diuretics
US4504669A (en) *	1981-02-25	1985-03-12	Hoechst-Roussel Pharmaceuticals Inc.	1,2-Benzisoxazoloxyethylamines and intermediates for the preparation thereof
US4427691A (en) *	1981-02-25	1984-01-24	Hoechst-Roussel Pharmaceuticals Inc.	1,2-Benzisoxazoloxyethylamines and intermediates for the preparation thereof
US4644064A (en) *	1981-02-25	1987-02-17	Hoechst-Roussel Pharmaceuticals Inc.	1,2-benzisoxazoloxyethylamines and intermediates for the preparation thereof
US4452804A (en) *	1981-02-25	1984-06-05	Hoechst-Roussel Pharmaceuticals Inc.	1,2-Benzisoxazoloxyethylamines and intermediates for the preparation thereof
JPS59128347A (en) *	1983-01-12	1984-07-24	Daikin Ind Ltd	Fluorine-containing benzophenone derivative
US4458076A (en) *	1983-05-31	1984-07-03	Hoechst-Roussel Pharmaceuticals	3-(4-Piperidinyl)-1,2-benzisothiazoles
GB9620202D0 (en) *	1996-09-27	1996-11-13	Rhone Poulenc Agriculture	New herbicides
TW200637839A (en) *	2005-01-07	2006-11-01	Taisho Pharmaceutical Co Ltd	1-thio-d-glucitol derivatives
WO2008035359A2 (en) *	2006-06-12	2008-03-27	Cadila Healthcare Limited	Oximinophenoxyalkanoic acid and phenylalkanoic acid derivatives
AR081930A1 (en) *	2010-06-16	2012-10-31	Ardea Biosciences Inc	THIOACETATE COMPOUNDS

1978
- 1978-11-15 ES ES475100A patent/ES475100A1/en not_active Expired
- 1978-11-17 IT IT7829897A patent/IT7829897A0/en unknown
- 1978-11-17 FI FI783515A patent/FI783515A/en not_active Application Discontinuation
- 1978-11-20 PT PT68807A patent/PT68807A/en unknown
- 1978-11-20 DE DE7878101409T patent/DE2861637D1/en not_active Expired
- 1978-11-20 NO NO783908A patent/NO783908L/en unknown
- 1978-11-20 AU AU41716/78A patent/AU521533B2/en not_active Expired
- 1978-11-20 NZ NZ188946A patent/NZ188946A/en unknown
- 1978-11-20 AT AT0824478A patent/AT371811B/en not_active IP Right Cessation
- 1978-11-20 DK DK515978A patent/DK515978A/en not_active Application Discontinuation
- 1978-11-20 IL IL55997A patent/IL55997A0/en unknown
- 1978-11-20 CA CA316,532A patent/CA1111853A/en not_active Expired
- 1978-11-20 IE IE2275/78A patent/IE47299B1/en unknown
- 1978-11-20 EP EP78101409A patent/EP0002666B1/en not_active Expired
- 1978-11-20 HU HU78HO2116A patent/HU180785B/en unknown
- 1978-11-21 EG EG662/78A patent/EG13533A/en active
- 1978-11-21 JP JP14402578A patent/JPS5495563A/en active Pending
- 1978-11-21 GR GR57693A patent/GR72950B/el unknown
1979
- 1979-06-29 ES ES482056A patent/ES482056A1/en not_active Expired
- 1979-06-29 ES ES482055A patent/ES482055A1/en not_active Expired

Also Published As

Publication number	Publication date
PT68807A (en)	1978-12-01
EP0002666A1 (en)	1979-07-11
AU4171678A (en)	1979-05-31
AT371811B (en)	1983-08-10
JPS5495563A (en)	1979-07-28
DK515978A (en)	1979-05-22
ES475100A1 (en)	1979-12-01
HU180785B (en)	1983-04-29
IE782275L (en)	1979-05-21
IL55997A0 (en)	1979-01-31
DE2861637D1 (en)	1982-03-25
CA1111853A (en)	1981-11-03
IE47299B1 (en)	1984-02-08
EP0002666B1 (en)	1982-02-17
NZ188946A (en)	1983-05-10
ATA824478A (en)	1982-12-15
GR72950B (en)	1984-01-17
EG13533A (en)	1981-12-31
IT7829897A0 (en)	1978-11-17
ES482055A1 (en)	1980-09-01
NO783908L (en)	1979-05-22
ES482056A1 (en)	1980-09-01
FI783515A (en)	1979-05-22

Publication	Publication Date	Title
AU574041B2 (en)	1988-06-30	4(5-fluoromethyl-2-pyridyloxy)phenoxyalkanecarboxylic acids
AU509680B2 (en)	1980-05-22	1,9-dihydroxyoctahydrophenanthrenes
AU521102B2 (en)	1982-03-18	2, 6-diaminonebularines
AU520250B2 (en)	1982-01-21	4-aminomethyl-1-93,3,3-triarylpropyl)-4-arylpiperidine and related compounds
AU4622079A (en)	1979-10-25	Substituted 1,3-diaryl-2-imino-imidazolidines and 2-imino- hexahydro-pyrimidines
AU513456B2 (en)	1980-12-04	l-Azaxanthone-3-carboxylic acids
AU521533B2 (en)	1982-04-08	1, 2-benzisoxazolozyacetic acids and related compounds
AU526584B2 (en)	1983-01-20	2,3-dicyanopyrazine derivatives
AU6011480A (en)	1981-01-15	7 aminothiadiazoylacetamido - cephalosporins
AU531142B2 (en)	1983-08-11	2 amino- pyimindones
AU527943B2 (en)	1983-03-31	2, 4-diamino-5-benzylpyrimidines
AU515140B2 (en)	1981-03-19	2, 4, 7-triamino-pteridine derivatives
AU512608B2 (en)	1980-10-16	4'Homoisotwistane derivatives
AU505434B1 (en)	1979-11-22	2, 5 diketogluconic acid
AU518208B2 (en)	1981-09-17	2,4-dichlorophenyl-triazolyl-ethan-one and -ol derivatives
AU515232B2 (en)	1981-03-26	A-nor-androsta-3(5)16 dien-2-ones
AU529528B2 (en)	1983-06-09	5 alpha-pre gnan-20-ols
AU518292B2 (en)	1981-09-24	1,4-benzoxathin-2-carboxamides
AU505664B2 (en)	1979-11-29	2, 1, 3-benzothiadiazoles
AU517889B2 (en)	1981-09-03	2, 6-METHANO-2H-l-BENZOXOCINS
AU514017B2 (en)	1979-11-01	5-sulfamoyl-orthanilic acids
AU514068B2 (en)	1979-07-26	4'Deoxyvincristine and related compounds
AU516080B2 (en)	1981-05-14	1, 2, 3-thiadiazolin-2-ide derivatives
AU497296B2 (en)	1978-12-07	3'deoxybutirosin aand b
AU3548678A (en)	1979-11-01	5-sulfamoyl-orthanilic acids