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AU509357B2 - Prostacyclin analogs - Google Patents

Prostacyclin analogs

Info

Publication number
AU509357B2
AU509357B2 AU28206/77A AU2820677A AU509357B2 AU 509357 B2 AU509357 B2 AU 509357B2 AU 28206/77 A AU28206/77 A AU 28206/77A AU 2820677 A AU2820677 A AU 2820677A AU 509357 B2 AU509357 B2 AU 509357B2
Authority
AU
Australia
Prior art keywords
prostacyclin analogs
prostacyclin
analogs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU28206/77A
Other versions
AU2820677A (en
Inventor
RA. and Sid JC Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AU2820677A publication Critical patent/AU2820677A/en
Application granted granted Critical
Publication of AU509357B2 publication Critical patent/AU509357B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
AU28206/77A 1977-04-19 1977-08-25 Prostacyclin analogs Expired AU509357B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78814377A 1977-04-19 1977-04-19
US78814477A 1977-04-19 1977-04-19
USUS788143 1977-04-19
USUS788144 1977-04-19

Publications (2)

Publication Number Publication Date
AU2820677A AU2820677A (en) 1979-03-01
AU509357B2 true AU509357B2 (en) 1980-05-08

Family

ID=27120750

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28206/77A Expired AU509357B2 (en) 1977-04-19 1977-08-25 Prostacyclin analogs

Country Status (9)

Country Link
JP (1) JPS53132573A (en)
AU (1) AU509357B2 (en)
CA (1) CA1184906A (en)
CH (1) CH636347A5 (en)
DE (1) DE2746932A1 (en)
FR (1) FR2387975A1 (en)
GB (1) GB1554050A (en)
NL (1) NL7800011A (en)
SE (1) SE434266B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206127A (en) * 1977-11-23 1980-06-03 Miles Laboratories, Inc. 5,6-Dihydro analogues of prostaglandin I2
JPH02294718A (en) * 1989-05-09 1990-12-05 Fujitsu Ltd Digital signal input circuit
DE60039727D1 (en) * 1999-10-15 2008-09-11 Sucampo Ag New composition containing a bicyclic compound and a glyceride
MX2012000889A (en) 2009-07-28 2012-02-13 Ono Pharmaceutical Co Bicyclic compound and use thereof for medical purposes.
JP5835236B2 (en) 2011-01-27 2015-12-24 小野薬品工業株式会社 Bicyclic compounds and their pharmaceutical uses
ES2581852T3 (en) * 2011-01-27 2016-09-07 Ono Pharmaceutical Co., Ltd. Bicyclic compound and use thereof for medical purposes
ES2890989T3 (en) 2016-06-30 2022-01-25 Ono Pharmaceutical Co Method for producing a bicyclic compound

Also Published As

Publication number Publication date
SE434266B (en) 1984-07-16
JPS6151597B2 (en) 1986-11-10
CA1184906A (en) 1985-04-02
DE2746932A1 (en) 1978-11-02
DE2746932C2 (en) 1988-03-31
FR2387975A1 (en) 1978-11-17
SE7709477L (en) 1978-10-20
GB1554050A (en) 1979-10-17
NL7800011A (en) 1978-10-23
AU2820677A (en) 1979-03-01
FR2387975B1 (en) 1980-08-08
CH636347A5 (en) 1983-05-31
JPS53132573A (en) 1978-11-18

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