[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

AU4587189A - Improvements in or relating to organic compounds - Google Patents

Improvements in or relating to organic compounds

Info

Publication number
AU4587189A
AU4587189A AU45871/89A AU4587189A AU4587189A AU 4587189 A AU4587189 A AU 4587189A AU 45871/89 A AU45871/89 A AU 45871/89A AU 4587189 A AU4587189 A AU 4587189A AU 4587189 A AU4587189 A AU 4587189A
Authority
AU
Australia
Prior art keywords
relating
organic compounds
compounds
organic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU45871/89A
Other versions
AU633859B2 (en
Inventor
Rainer Albert
Eric P. Krenning
Steven W.J. Lamberts
Janos Pless
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888828364A external-priority patent/GB8828364D0/en
Priority claimed from GB898916115A external-priority patent/GB8916115D0/en
Priority claimed from GB898916761A external-priority patent/GB8916761D0/en
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU4587189A publication Critical patent/AU4587189A/en
Application granted granted Critical
Publication of AU633859B2 publication Critical patent/AU633859B2/en
Assigned to NOVARTIS AG reassignment NOVARTIS AG Request to Amend Deed and Register Assignors: SANDOZ LTD.
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU45871/89A 1988-12-05 1989-12-04 Improvements in or relating to organic compounds Expired AU633859B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8828364 1988-12-05
GB888828364A GB8828364D0 (en) 1988-12-05 1988-12-05 Improvements in/relating to organic compounds
GB8916115 1989-07-13
GB898916115A GB8916115D0 (en) 1989-07-13 1989-07-13 Improvements in or relating to organic compounds
GB898916761A GB8916761D0 (en) 1989-07-21 1989-07-21 Improvements in or relating to organic compounds
GB8916761 1989-07-21

Publications (2)

Publication Number Publication Date
AU4587189A true AU4587189A (en) 1990-06-14
AU633859B2 AU633859B2 (en) 1993-02-11

Family

ID=27264222

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45871/89A Expired AU633859B2 (en) 1988-12-05 1989-12-04 Improvements in or relating to organic compounds

Country Status (24)

Country Link
JP (2) JP2726320B2 (en)
KR (1) KR0156541B1 (en)
AT (1) AT403476B (en)
AU (1) AU633859B2 (en)
BE (1) BE1002296A5 (en)
CA (1) CA2004532C (en)
CH (1) CH678329A5 (en)
DE (1) DE3991505B4 (en)
DK (1) DK175338B1 (en)
ES (1) ES2023533A6 (en)
FI (1) FI102540B (en)
FR (1) FR2639947B1 (en)
GB (1) GB2225579B (en)
HK (1) HK189995A (en)
HU (2) HUT53375A (en)
IE (1) IE62091B1 (en)
IL (1) IL92534A (en)
LU (1) LU87633A1 (en)
MY (1) MY106120A (en)
NL (1) NL194828C (en)
PT (1) PT92487B (en)
SA (1) SA96160495B1 (en)
SE (1) SE508799C2 (en)
WO (1) WO1990006949A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU618270B2 (en) * 1987-07-10 1991-12-19 Novartis Ag Improvements in or relating to organic compounds
AU639371B2 (en) * 1987-07-10 1993-07-22 Novartis Ag Method of treating breast cancer

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
US5700444A (en) * 1992-02-20 1997-12-23 Rhomed Incorporated Chemotactic peptide pharmaceutical applications
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
US5460785A (en) * 1989-08-09 1995-10-24 Rhomed Incorporated Direct labeling of antibodies and other protein with metal ions
GB9004017D0 (en) * 1990-02-22 1990-04-18 Krenning Eric P Improvements in or relating to organic compounds
US5382654A (en) * 1992-02-05 1995-01-17 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
PT100111B (en) * 1991-02-08 1999-06-30 Biomeasure Inc COMPOSITION FOR THE TREATMENT OF A MAMIFERO SUFFERING FROM PROLIFERATIVE DAPELE, BENIGN OR MALIGNA DISEASE, COMPREHENDING A SOMATOSTATIN ANALOGUE
US7238340B1 (en) 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
AU657770B2 (en) * 1991-06-03 1995-03-23 Mallinckrodt Medical, Inc. Radiolabelled somatostatin derivatives, their preparation and use
DK0600992T3 (en) * 1991-08-29 2000-10-09 Mallinckrodt Medical Inc Use of gentisic acid or gentisyl alcohol to stabilize radiolabelled peptides and proteins
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
US5556609A (en) * 1992-02-20 1996-09-17 Rhomed Incorporated YIGSR peptide radiopharmaceutical applications
EP0629133B1 (en) * 1992-01-03 2000-11-29 Rhomed, Incorporated Peptide-metal ion pharmaceutical applications
US5738838A (en) * 1992-02-20 1998-04-14 Rhomed Incorporated IKVAV peptide radiopharmaceutical applications
US5371184A (en) * 1992-02-05 1994-12-06 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
JPH08504166A (en) * 1992-02-05 1996-05-07 マリンクロッド・メディカル・インコーポレイテッド Radiolabeled peptide compound
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
JPH07505621A (en) * 1992-03-25 1995-06-22 マリンクロッド・インコーポレイテッド Detection and detection of tumor tissue during surgery
US5871711A (en) * 1992-06-23 1999-02-16 Diatide, Inc. Radioactively-labeled somatostatin-derived peptides for imaging and therapeutic uses
US5716596A (en) * 1992-06-23 1998-02-10 Diatide, Inc. Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
US5620675A (en) 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
NZ250653A (en) * 1993-01-12 1995-12-21 Sandoz Ltd Somatostatin derivatives and pharmaceutical or diagnostic imaging compositions
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
EP0683676A4 (en) * 1993-02-02 1998-09-30 Neorx Corp Directed biodistribution of small molecules.
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5932189A (en) * 1994-07-29 1999-08-03 Diatech, Inc. Cyclic peptide somatostatin analogs
SG93839A1 (en) * 1993-07-15 2003-01-21 Diatide Inc Radiolabeled peptides
CA2190727C (en) * 1994-05-19 2006-07-18 Sudhakar Kasina Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
GB9417873D0 (en) 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
US5632969A (en) * 1994-10-13 1997-05-27 Merck & Co., Inc. N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
US5556939A (en) * 1994-10-13 1996-09-17 Merck Frosst Canada, Inc. TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications
US5830431A (en) * 1995-06-07 1998-11-03 Mallinckrodt Medical, Inc. Radiolabeled peptide compositions for site-specific targeting
GB9708265D0 (en) 1997-04-24 1997-06-18 Nycomed Imaging As Contrast agents
FI965181A (en) 1996-12-20 1998-06-21 Map Medical Technologies Oy Polyalcohol peptide derivatives
US7175953B2 (en) 1999-04-09 2007-02-13 Institute Fuer Diagnostik Forschung Short-warp peptide-dye conjugate as contrast agent for optical diagnostic
US6630570B1 (en) 1999-04-09 2003-10-07 Insitut für Diagnostikforschung GmbH Short-chain peptide-dye conjugates as contrast media for optical diagnosis
DE19917713A1 (en) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Short-chain peptide-dye conjugates as contrast agents for optical diagnostics
US6685914B1 (en) 1999-09-13 2004-02-03 Bristol-Myers Squibb Pharma Company Macrocyclic chelants for metallopharmaceuticals
JP5398945B2 (en) * 2001-04-23 2014-01-29 マリンクロッド エルエルシー Tc and Re labeled radioactive glycosylated octreotide derivatives
US7968080B2 (en) 2003-08-20 2011-06-28 The Regents Of The University Of California Somatostatin analogs with inhibitory activity to growth hormone release
JP5395327B2 (en) * 2003-09-17 2014-01-22 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム Mechanism-based targeted pancreatic beta cell imaging and therapy
EP2067786A1 (en) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Novel non selective analogs of somatostatin
US9480759B2 (en) 2012-11-21 2016-11-01 Serene, Llc Tin-117m somatostatin receptor binding compounds and methods

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1222691A (en) * 1981-12-29 1987-06-09 Wilhelmus T. Goedemans Method of preparing radionuclide-labelled proteins, in particular antibodies or antibody fragments
US4652519A (en) * 1983-02-03 1987-03-24 Yeda Research And Development Company Limited Bifunctional chelating agents and process for their production
US4707352A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
DE3511206A1 (en) * 1985-03-28 1986-10-09 Sandoz-Patent-GmbH, 7850 Lörrach Polypeptide derivatives, their preparation and pharmaceutical products which contain these polypeptide derivatives
DE3522638A1 (en) * 1985-06-25 1987-01-08 Diamalt Ag NEW SOMATOSTATIN DERIVATIVES
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
DK172629B1 (en) * 1986-02-14 1999-03-22 Nihon Mediphysics Co Ltd Reactive high molecular weight compounds with at least one free amino group, high molecular weight compounds combined with a physiological
US4732974A (en) * 1986-03-05 1988-03-22 Mallinckrodt, Inc. Metal ion labeling of carrier molecules
US4861869A (en) * 1986-05-29 1989-08-29 Mallinckrodt, Inc. Coupling agents for joining radionuclide metal ions with biologically useful proteins
HU206890B (en) * 1986-10-13 1993-01-28 Sandoz Ag Process for producing sugar-modified somatostatin peptide derivatives and pharmaceutical compositions containing them as active components
CH679045A5 (en) * 1987-06-29 1991-12-13 Sandoz Ag
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
BE1003762A3 (en) * 1988-11-11 1992-06-09 Sandoz Sa New therapeutic use somatostatin and analogues and derivatives.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU618270B2 (en) * 1987-07-10 1991-12-19 Novartis Ag Improvements in or relating to organic compounds
AU639371B2 (en) * 1987-07-10 1993-07-22 Novartis Ag Method of treating breast cancer

Also Published As

Publication number Publication date
GB2225579A (en) 1990-06-06
FI895809A0 (en) 1989-12-04
IL92534A (en) 1994-06-24
LU87633A1 (en) 1991-09-18
NL8902981A (en) 1990-07-02
BE1002296A5 (en) 1990-11-20
CA2004532A1 (en) 1990-06-05
SE508799C2 (en) 1998-11-09
GB8927255D0 (en) 1990-01-31
FI102540B1 (en) 1998-12-31
FR2639947B1 (en) 1995-04-21
KR0156541B1 (en) 1998-10-15
IE893866L (en) 1990-06-05
FI102540B (en) 1998-12-31
SE8904087L (en) 1991-06-05
HU211468A9 (en) 1995-11-28
HK189995A (en) 1995-12-29
WO1990006949A2 (en) 1990-06-28
ATA901789A (en) 1997-07-15
KR900009697A (en) 1990-07-05
AT403476B (en) 1998-02-25
JP2726320B2 (en) 1998-03-11
SA96160495B1 (en) 2006-08-23
CA2004532C (en) 2000-02-22
SE8904087D0 (en) 1989-12-04
DK612689A (en) 1990-06-06
GB2225579B (en) 1993-03-17
NL194828C (en) 2003-04-03
DK175338B1 (en) 2004-08-30
ES2023533A6 (en) 1992-01-16
HU896359D0 (en) 1990-02-28
JPH1095737A (en) 1998-04-14
JPH02184698A (en) 1990-07-19
CH678329A5 (en) 1991-08-30
PT92487A (en) 1990-06-29
WO1990006949A3 (en) 1990-07-26
MY106120A (en) 1995-03-31
NL194828B (en) 2002-12-02
IE62091B1 (en) 1994-12-14
JP3686503B2 (en) 2005-08-24
HUT53375A (en) 1990-10-28
AU633859B2 (en) 1993-02-11
DE3991505B4 (en) 2006-04-20
PT92487B (en) 1996-01-31
DK612689D0 (en) 1989-12-05
FR2639947A1 (en) 1990-06-08

Similar Documents

Publication Publication Date Title
AU4140089A (en) Improvements in or relating to organic compounds
AU4587189A (en) Improvements in or relating to organic compounds
AU1892088A (en) Improvements in or relating to organic compounds
AU3263789A (en) Improvements in or relating to organic compounds
AU2490288A (en) Improvements in or relating to organic compounds
AU2417588A (en) Improvements in or relating to organic compounds
AU1889388A (en) Improvements in or relating to organic compounds
AU7558787A (en) Improvements in or relating to organic compounds
AU1840988A (en) Improvements in or relating to organic compounds
AU3901789A (en) Improvements in or relating to organic compounds
AU3131389A (en) Improvements in or relating to organic compounds
AU6314090A (en) Improvements in or relating to organic compounds
AU4453589A (en) Improvements in or relating to organic compounds
AU8057587A (en) Improvements in or relating to organic compounds
AU5060190A (en) Improvements in or relating to organic compounds
AU1560588A (en) Improvements in or relating to organic compounds
AU4616189A (en) Improvements in or relating to organic compounds
AU3116489A (en) Improvements in or relating to organic compounds
AU2284588A (en) Improvements in or relating to organic compounds
GB8829330D0 (en) Improvements in or relating to organic compounds
AU7525987A (en) Improvements in or relating to organic compounds
AU7932587A (en) Improvements in or relating to organic compounds
AU606908C (en) Improvements in or relating to organic compounds
AU8282887A (en) Improvements in or relating to organic compounds
GB8830136D0 (en) Improvements in or relating to organic compounds