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AU3735899A - Amphiphilic polysaccharide derivatives - Google Patents

Amphiphilic polysaccharide derivatives

Info

Publication number
AU3735899A
AU3735899A AU37358/99A AU3735899A AU3735899A AU 3735899 A AU3735899 A AU 3735899A AU 37358/99 A AU37358/99 A AU 37358/99A AU 3735899 A AU3735899 A AU 3735899A AU 3735899 A AU3735899 A AU 3735899A
Authority
AU
Australia
Prior art keywords
polysaccharide derivatives
amphiphilic polysaccharide
amphiphilic
derivatives
polysaccharide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU37358/99A
Inventor
Youngro Byun
Yong Kyu Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mediplex Corp Korea
Original Assignee
Mediplex Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1019990014003A external-priority patent/KR100314496B1/en
Application filed by Mediplex Corp Korea filed Critical Mediplex Corp Korea
Publication of AU3735899A publication Critical patent/AU3735899A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542Carboxylic acids, e.g. a fatty acid or an amino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/554Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being a steroid plant sterol, glycyrrhetic acid, enoxolone or bile acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
AU37358/99A 1998-05-28 1999-05-14 Amphiphilic polysaccharide derivatives Abandoned AU3735899A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
KR9819469 1998-05-28
KR19980019469 1998-05-28
KR1019990014003A KR100314496B1 (en) 1998-05-28 1999-04-20 Non-thrombogenic heparin derivatives, process for preparation and use thereof
KR9914003 1999-04-20
US09300173 1999-04-27
US09/300,173 US6245753B1 (en) 1998-05-28 1999-04-27 Amphiphilic polysaccharide derivatives
PCT/KR1999/000242 WO1999061481A1 (en) 1998-05-28 1999-05-14 Amphiphilic polysaccharide derivatives

Publications (1)

Publication Number Publication Date
AU3735899A true AU3735899A (en) 1999-12-13

Family

ID=27349744

Family Applications (1)

Application Number Title Priority Date Filing Date
AU37358/99A Abandoned AU3735899A (en) 1998-05-28 1999-05-14 Amphiphilic polysaccharide derivatives

Country Status (5)

Country Link
JP (1) JP3541007B2 (en)
AU (1) AU3735899A (en)
DE (1) DE19981169B4 (en)
GB (1) GB2342357B (en)
WO (1) WO1999061481A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7772220B2 (en) 2004-10-15 2010-08-10 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
US7932243B2 (en) 1998-07-24 2011-04-26 Seo Hong Yoo Bile preparations for gastrointestinal disorders
US8772691B2 (en) 2003-06-23 2014-07-08 Abl Ip Holding Llc Optical integrating cavity lighting system using multiple LED light sources

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6656922B2 (en) * 1998-05-28 2003-12-02 Mediplex Corporation, Korea Oral delivery of macromolecules
US7303768B2 (en) 1998-07-24 2007-12-04 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
KR100378109B1 (en) * 2000-10-24 2003-03-29 주식회사 메디프렉스 Hydrophobic multicomponant heparin conjugates, a preparing method and a use thereof
CN1531436A (en) * 2001-05-09 2004-09-22 (株)美大富历寿 Amphiphilic heparin derivative formulations for enhanced mucosal absorption
FR2864091B1 (en) * 2003-12-19 2006-04-07 Ethypharm Sa AMPHIPHILE HEPARIN DERIVATIVE FORMED BY COUPLING HEPARIN WITH A BILARY ACID
ATE458489T1 (en) 2004-08-30 2010-03-15 Seo Hong Yoo NERVE PROTECTIVE EFFECT OF DISSOLVED UDCA IN A FOCAL ISCHEMIC MODEL
MX340993B (en) 2007-02-08 2016-08-02 Emisphere Tech Inc * Phenylalkylcarboxylic acid delivery agents.
US20110144281A1 (en) * 2007-12-05 2011-06-16 Valorisation-Recherche, Societe En Commandite Amphiphilic polymers having a cholane core
EP2360188B1 (en) * 2008-11-05 2014-09-17 National University Corporation Tokyo Medical and Dental University Hyaluronic acid derivative and pharmaceutical composition thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB891554A (en) * 1959-10-19 1962-03-14 Applic Chimiques D Etudes Et D Galenic suppository containing salts of heparin
US3482014A (en) * 1966-06-29 1969-12-02 Canada Packers Ltd Orally active heparin and method for making and using same
WO1995012620A1 (en) * 1993-11-01 1995-05-11 Alpha-Beta Technology, Inc. Derivatized polysaccharide bile acid sequestrant for reducing cholesterol
JPH07206903A (en) * 1994-01-24 1995-08-08 Takeda Chem Ind Ltd Aggregate of super molecule structure type

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7932243B2 (en) 1998-07-24 2011-04-26 Seo Hong Yoo Bile preparations for gastrointestinal disorders
US8772691B2 (en) 2003-06-23 2014-07-08 Abl Ip Holding Llc Optical integrating cavity lighting system using multiple LED light sources
US7772220B2 (en) 2004-10-15 2010-08-10 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound

Also Published As

Publication number Publication date
WO1999061481A1 (en) 1999-12-02
JP3541007B2 (en) 2004-07-07
GB2342357B (en) 2002-03-27
DE19981169B4 (en) 2007-09-13
JP2002516355A (en) 2002-06-04
GB2342357A (en) 2000-04-12
DE19981169T1 (en) 2000-11-16
GB0001794D0 (en) 2000-03-22

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase