AU3665293A - Chimeric toxins binding to the GnRH receptor - Google Patents

Chimeric toxins binding to the GnRH receptor

Info

Publication number: AU3665293A
Authority: AU; Australia
Prior art keywords: gnrh receptor; chimeric toxins; binding; toxins binding; chimeric
Prior art date: 1992-02-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU36652/93A

Inventor

Victoria K Lombardo

Stephen Marburg

Richard L. Tolman

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck and Co Inc

Original Assignee

Merck and Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-14

Filing date

1993-02-12

Publication date

1993-09-03

1993-02-12 Application filed by Merck and Co Inc filed Critical Merck and Co Inc

1993-09-03 Publication of AU3665293A publication Critical patent/AU3665293A/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Endocrinology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AU36652/93A 1992-02-14 1993-02-12 Chimeric toxins binding to the GnRH receptor Abandoned AU3665293A (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US83603192A	1992-02-14	1992-02-14
US836031		1992-02-14
US918693A	1993-01-26	1993-01-26
US009186		1993-01-26

Publications (1)

Publication Number	Publication Date
AU3665293A true AU3665293A (en)	1993-09-03

Family

ID=26679168

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU36652/93A Abandoned AU3665293A (en)	1992-02-14	1993-02-12	Chimeric toxins binding to the GnRH receptor

Country Status (2)

Country	Link
AU (1)	AU3665293A (en)
WO (1)	WO1993015751A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU7468196A (en) *	1995-10-27	1997-05-15	Merck & Co., Inc.	Conjugates of gonadotropin releasing hormone
JPH11514380A (en) *	1995-10-27	1999-12-07	メルクエンドカンパニーインコーポレーテッド	GnRH / Pseudomonas reduced bacterial exotoxin conjugate
IL116436A (en)	1995-12-18	2006-12-31	Yissum Res Dev Co	Fc?Á-PE CHIMERIC PROTEIN FOR TARGETED TREATMENT OF ALLERGY RESPONSES AND
IL118570A (en) *	1996-06-04	2007-06-17	Shai Yarkoni	USE OF A CHIMERIC PROTEIN COMPRISING Met-GnRH IN THE PREPARATION OF A PHARMACEUTICAL COMPOSITION FOR TREATING ADENOCARCINOMA OR HEPATOCARCINOMA
AU6587998A (en) *	1997-03-27	1998-10-20	Demeter Biotechnologies, Ltd.	Ligand/lytic peptide compositions and methods of use
US6635740B1 (en)	1997-03-27	2003-10-21	Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College	Ligand/lytic peptide compositions and methods of use
EP1878438B1 (en) *	1997-03-27	2017-11-29	Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College	Ligand/lytic peptide compositions and methods of use
DE59709788D1 (en) *	1997-05-09	2003-05-15	Deutsches Krebsforsch	Conjugate comprising a folic acid antagonist and a carrier
US6680058B1 (en)	1997-09-03	2004-01-20	Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College	Compositions and methods for contraception in or sterilization of mammals
US9006388B2 (en) *	2003-03-26	2015-04-14	Sudhir Paul	Covalent attachment of ligands to nucleophilic proteins guided by non-covalent
CA3028134A1 (en)	2016-06-17	2017-12-21	Magenta Therapeutics, Inc.	Compositions and methods for the depletion of cd117+ cells
IL268058B2 (en)	2017-01-20	2023-09-01	Magenta Therapeutics Inc	Compositions and methods for the depletion of cd137plus cells
CN109248324B (en) *	2018-10-16	2021-11-30	承德医学院	GnRH analogue-anti-tumor drug conjugate, preparation method and application thereof
WO2020220085A1 (en) *	2019-05-02	2020-11-05	The University Of Sydney	Peptide derivatives and conjugates thereof for treating cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4855285A (en) *	1985-12-04	1989-08-08	The Ohio State University Research Foundation	Antigenic modification of polypeptides
GB2228262B (en) *	1989-01-25	1992-10-07	Nat Inst Immunology	Antigenic derivative of gnrh
WO1990009799A1 (en) *	1989-02-23	1990-09-07	Colorado State University Research Foundation	GnRH ANALOGS FOR DESTROYING GONADOTROPHS

1993
- 1993-02-12 WO PCT/US1993/001263 patent/WO1993015751A1/en active Application Filing
- 1993-02-12 AU AU36652/93A patent/AU3665293A/en not_active Abandoned

Also Published As

Publication number	Publication date
WO1993015751A1 (en)	1993-08-19

Publication	Publication Date	Title
GB9322501D0 (en)	1993-12-22	Fusion peptides with binding for streptavidin
AU1872595A (en)	1995-08-21	Peptides and compounds that bind to the il-1 receptor
GB9225453D0 (en)	1993-01-27	Binding proteins
AU5671994A (en)	1994-06-22	Case-bound hot-melt binding system
EP0593174A3 (en)	1996-09-04	Dual actuator dasd
EP0568021A3 (en)	1995-11-22	Binder composition
AU6080794A (en)	1994-08-15	Antibodies directed against binding-associated epitopes
AU671148C (en)	1994-04-21	Binding element
AU3665293A (en)	1993-09-03	Chimeric toxins binding to the GnRH receptor
AU5664094A (en)	1995-04-18	Two-way mailer
AU8974891A (en)	1992-06-25	Gasoline composition
EP0672132A4 (en)	1995-05-23	Receptor internalization signals.
AU4968893A (en)	1994-03-15	Bacteriocin
ZA937445B (en)	1994-04-26	Binding element
ZA93988B (en)	1993-09-20	Chimeric toxins binding to the GnRH receptor.
AU5009993A (en)	1994-03-15	Isoprostane-protein conjugates
GB9212045D0 (en)	1992-07-22	Binding
AU4881093A (en)	1994-04-21	Glue-based binding system
AU7947994A (en)	1995-05-23	Improvement to electromagnetotherapy apparatuses
AU4683297A (en)	1998-02-26	Linkage arrangement
ZA941207B (en)	1995-01-03	Binder composition.
AU5336694A (en)	1994-05-09	Bituminous binder composition
AU6060594A (en)	1994-10-27	Improvements to vehicles
AU6424196A (en)	1996-10-31	Element for composite structural member
ZA941022B (en)	1994-09-01	Kindler