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AU3510200A - Human dickkopf-related protein and nucleic acid molecules and uses therefor - Google Patents

Human dickkopf-related protein and nucleic acid molecules and uses therefor

Info

Publication number
AU3510200A
AU3510200A AU35102/00A AU3510200A AU3510200A AU 3510200 A AU3510200 A AU 3510200A AU 35102/00 A AU35102/00 A AU 35102/00A AU 3510200 A AU3510200 A AU 3510200A AU 3510200 A AU3510200 A AU 3510200A
Authority
AU
Australia
Prior art keywords
nucleic acid
acid molecules
related protein
uses therefor
human dickkopf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU35102/00A
Inventor
Sean Mccarthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Publication of AU3510200A publication Critical patent/AU3510200A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4718—Cytokine-induced proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU35102/00A 1999-03-05 2000-03-03 Human dickkopf-related protein and nucleic acid molecules and uses therefor Abandoned AU3510200A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26302299A 1999-03-05 1999-03-05
US09263022 1999-03-05
PCT/US2000/005452 WO2000052047A2 (en) 1999-03-05 2000-03-03 Human dickkopf-related protein and nucleic acid molecules and uses therefor

Publications (1)

Publication Number Publication Date
AU3510200A true AU3510200A (en) 2000-09-21

Family

ID=23000057

Family Applications (1)

Application Number Title Priority Date Filing Date
AU35102/00A Abandoned AU3510200A (en) 1999-03-05 2000-03-03 Human dickkopf-related protein and nucleic acid molecules and uses therefor

Country Status (4)

Country Link
EP (1) EP1161445A2 (en)
AU (1) AU3510200A (en)
CA (1) CA2366062C (en)
WO (1) WO2000052047A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE255229T1 (en) * 2000-02-24 2003-12-15 Oxford Glycosciences Uk Ltd DPI-6, A THERAPEUTIC BIOMARKER IN NEUROLOGICAL DISEASES
EP1222933A1 (en) * 2001-01-15 2002-07-17 Academisch Ziekenhuis Leiden h.o.d.n., Leids Universitair Medisch Centrum Generation and/or reduction of new lung tissue in an affected lung, by modulation of the Wnt-pathway
IL157328A0 (en) * 2001-02-16 2004-02-19 Genentech Inc Treatment involving dkk-1 or antagonists thereof
US7736654B2 (en) 2001-04-10 2010-06-15 Agensys, Inc. Nucleic acids and corresponding proteins useful in the detection and treatment of various cancers
BR0209836A (en) * 2001-05-17 2004-12-07 Genome Therapeutics Corp Method for regulating lrp5, lrp6 or hbm activity in a patient, and dkk-wnt pathway in a patient, to modulate bone mass and lipid levels in a patient, to diagnose high or low bone mass and / or high or low lipid levels in a patient to screen a compound that modulates dkk interaction with lrp5, lrp6, hbm or a dkk binding fragment of lrp5, lrp6 or hbm, and dkk with a protein that interacts with dkk, composition, pharmaceutical composition, methods for identifying compounds that modulate dkk and lrp5 / lrp6 / hbm interactions, and for identifying binding partners for a dkk protein, nucleic acid encoding a dkk-interacting peptide protein aptamer , vector, method for detecting a modulating activity of a transgenic animal compound, method for identifying potential compounds that modulate dkk activity, peptide aptamer, antibody or antibody fragment, and methods for identify dkk-interacting proteins by modulating dkk's interaction with the wnt signaling pathway, to identify compounds that modulate dkk's interaction with the wnt signaling pathway, to test compounds that modulate dkk-mediated activity in a mammal, and to screen compounds or compositions that modulate dkk interaction and a protein that interacts with dkk
US20040038860A1 (en) 2002-05-17 2004-02-26 Allen Kristina M. Reagents and methods for modulating dkk-mediated interactions
ES2304210B1 (en) * 2002-10-15 2009-09-28 Genentech, Inc USE OF DKK-5, PROCEDURE AND EQUIPMENT FOR DIAGNOSIS OF INSULIN AND HYBRIDOMA RESISTANT DISORDERS AND ANTIBODY AGAINST DKK-5.
US7811750B2 (en) * 2002-12-05 2010-10-12 Board Of Trustees Of The University Of Arkansas Molecular determinants of myeloma bone disease and use thereof
US8124087B2 (en) 2002-12-05 2012-02-28 Board Of Trustees Of The University Of Arkansas Methods of controlling bone loss by inhibiting DKK1
ES2362681T3 (en) * 2002-12-05 2011-07-11 The Board Of Trustees Of The University Of Arkansas MOLECULAR DETERMINANTS OF MYELOMA OSTEOPATHY AND USE OF THE SAME.
US8637506B2 (en) * 2003-09-22 2014-01-28 Enzo Biochem, Inc. Compositions and methods for bone formation and remodeling
US7622553B2 (en) 2003-11-17 2009-11-24 Merck & Co., Inc. Rhesus monkey dickkopf-1, nucleotides encoding same, and uses thereof
US7473770B2 (en) 2003-11-17 2009-01-06 Merck & Co., Inc. Cynomolgus monkey dickkopf-4, nucleotides encoding same, and uses thereof
US8343922B2 (en) * 2004-05-19 2013-01-01 Enzo Biochem, Inc. Compositions and methods for the stimulation or enhancement of bone formation and the self-renewal of cells
WO2006010534A1 (en) * 2004-07-28 2006-02-02 F.Hoffmann-La Roche Ag Dickkopf homolog 3 as target/marker of beta cell failure
EP2336177A1 (en) * 2004-08-04 2011-06-22 Amgen, Inc Antibodies to DKK-1
JP2008534017A (en) 2005-03-30 2008-08-28 ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド Modulators of DKKL-1 splice products for cancer diagnosis and therapy
WO2007104181A1 (en) * 2006-03-13 2007-09-20 Shanghai Cancer Institute Uses of dkk-1 protein in diagnosis of cancers
JP5936129B2 (en) * 2010-07-01 2016-06-15 国立大学法人 岡山大学 REIC / Dkk-3 protein partial domain polypeptide
KR20130021315A (en) * 2011-08-22 2013-03-05 인하대학교 산학협력단 Composition for preventing or treating erectile dysfunction comprising dkk2 protein or gene therefor and use thereof
JP2022539017A (en) * 2019-06-25 2022-09-07 フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ Promoters for specific expression of genes in cells expressing glial fibrillary acidic protein

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0954575A2 (en) * 1996-12-20 1999-11-10 Human Genome Sciences, Inc. Cerebellum and embryo specific protein
ATE505543T1 (en) * 1997-04-16 2011-04-15 Millennium Pharm Inc A COMPOSITION COMPRISING AN ANTIBODY THAT SELECTIVELY BINDS TO A CYSTEINE-RICH SECRETED PROTEIN (CRSP).
DE19747418C1 (en) * 1997-10-27 1999-07-15 Deutsches Krebsforsch Inhibitor protein of the wnt signaling pathway
DE19844293C2 (en) * 1998-09-18 2002-03-14 B & S Elektronische Geraete Gm lighting device

Also Published As

Publication number Publication date
CA2366062A1 (en) 2000-09-08
WO2000052047A9 (en) 2002-03-14
WO2000052047A3 (en) 2001-02-01
CA2366062C (en) 2014-06-17
EP1161445A2 (en) 2001-12-12
WO2000052047A2 (en) 2000-09-08

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase