AU2642492A - Peptide isoters containing a heterocycle as h.i.v. inhibitors - Google Patents

Peptide isoters containing a heterocycle as h.i.v. inhibitors

Info

Publication number: AU2642492A
Authority: AU; Australia
Prior art keywords: isoters; heterocycle; peptide; inhibitors; peptide isoters
Prior art date: 1991-09-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU26424/92A

Inventor

Geoffrey Bainbridge Dreyer

John Gerald Gleason

Thomas Downing Meek

Scott Kevin Thompson

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-11

Filing date

1992-09-11

Publication date

1993-04-05

1992-09-11 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

1993-04-05 Publication of AU2642492A publication Critical patent/AU2642492A/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AU26424/92A 1991-09-11 1992-09-11 Peptide isoters containing a heterocycle as h.i.v. inhibitors Abandoned AU2642492A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US75775191A	1991-09-11	1991-09-11
US757751		1991-09-11

Publications (1)

Publication Number	Publication Date
AU2642492A true AU2642492A (en)	1993-04-05

Family

ID=25049073

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU26424/92A Abandoned AU2642492A (en)	1991-09-11	1992-09-11	Peptide isoters containing a heterocycle as h.i.v. inhibitors

Country Status (7)

Country	Link
EP (1)	EP0603309A1 (en)
JP (1)	JPH06510766A (en)
AU (1)	AU2642492A (en)
MX (1)	MX9205222A (en)
PT (1)	PT100865A (en)
WO (1)	WO1993005026A1 (en)
ZA (1)	ZA926933B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1995007269A1 (en) *	1993-09-10	1995-03-16	Narhex Limited	Polar-substituted hydrocarbons
US5679688A (en) *	1992-03-11	1997-10-21	Narhex Limited	Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
US5888992A (en)	1992-03-11	1999-03-30	Narhex Limited	Polar substituted hydrocarbons
US6071895A (en)	1992-03-11	2000-06-06	Narhex Limited	Polar-substituted hydrocarbons
US6258806B1 (en)	1992-03-11	2001-07-10	Narhex Limited	Amine derivatives of oxo- and hydroxy- substituted hydrocarbons

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU4953796A (en) *	1995-03-15	1996-10-02	Sanyko Company, Limited	Dipeptide compounds having ahpba structure
CA2399214A1 (en)	2000-02-04	2001-08-09	Matthew Frank Brown	Novel heterocyclic amide derivatives
EP1450901A4 (en)	2001-12-10	2005-05-25	Bristol Myers Squibb Co	(1-phenyl-2-heteroaryl)ethyl-guanidine compounds as inhibitors of mitochondrial f1f0 atp hydrolase

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL89900A0 (en) *	1988-04-12	1989-12-15	Merck & Co Inc	Hiv protease inhibitors useful for the treatment of aids and pharmaceutical compositions containing them
IL91307A0 (en) *	1988-08-24	1990-03-19	Merck & Co Inc	Hiv protease inhibitors and pharmaceutical compositions for the treatment of aids containing them
WO1991010442A1 (en) *	1990-01-09	1991-07-25	Smithkline Beecham Corporation	Hiv protease inhibitors
CA2057369A1 (en) *	1990-12-17	1992-06-18	Ann E. Decamp	Stereocontrolled production of hydroxyester, hydroxyamide, and lactone compounds from chiral alpha-amino aldehydes

1992
- 1992-09-11 PT PT100865A patent/PT100865A/en not_active Application Discontinuation
- 1992-09-11 ZA ZA926933A patent/ZA926933B/en unknown
- 1992-09-11 JP JP5505523A patent/JPH06510766A/en active Pending
- 1992-09-11 EP EP92920181A patent/EP0603309A1/en not_active Withdrawn
- 1992-09-11 WO PCT/US1992/007747 patent/WO1993005026A1/en not_active Application Discontinuation
- 1992-09-11 MX MX9205222A patent/MX9205222A/en unknown
- 1992-09-11 AU AU26424/92A patent/AU2642492A/en not_active Abandoned

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5679688A (en) *	1992-03-11	1997-10-21	Narhex Limited	Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
US5888992A (en)	1992-03-11	1999-03-30	Narhex Limited	Polar substituted hydrocarbons
US5942504A (en) *	1992-03-11	1999-08-24	Narhex Limited	Amine derivatives of oxo- and hydroxy- substituted hydrocarbons
US6071895A (en)	1992-03-11	2000-06-06	Narhex Limited	Polar-substituted hydrocarbons
US6258806B1 (en)	1992-03-11	2001-07-10	Narhex Limited	Amine derivatives of oxo- and hydroxy- substituted hydrocarbons
WO1995007269A1 (en) *	1993-09-10	1995-03-16	Narhex Limited	Polar-substituted hydrocarbons

Also Published As

Publication number	Publication date
JPH06510766A (en)	1994-12-01
MX9205222A (en)	1993-03-01
PT100865A (en)	1994-01-31
EP0603309A1 (en)	1994-06-29
WO1993005026A1 (en)	1993-03-18
ZA926933B (en)	1994-03-09

Publication	Publication Date	Title
ZA929099B (en)	1993-06-07	New peptide derivatives.
AU9095391A (en)	1992-08-17	Aircraft-repair dock
AU4715493A (en)	1994-02-14	Peptide compounds
AU3463389A (en)	1989-11-30	Diol-containing renin inhibitors
AU1025792A (en)	1992-08-06	Amino acid derivatives
AU646617B2 (en)	1994-02-24	Container
AU1686792A (en)	1992-12-21	Injection container
AU1629792A (en)	1992-12-03	Gallium compounds
AU2642492A (en)	1993-04-05	Peptide isoters containing a heterocycle as h.i.v. inhibitors
AU2363992A (en)	1993-02-11	Valve arrangement
AU2402792A (en)	1993-03-02	Alkanamidoammonium compound
AU656027B2 (en)	1995-01-19	Saccharin derivative proteolytic enzime inhibitors
AU4721489A (en)	1990-07-05	Renin inhibitors
AU6855594A (en)	1995-01-24	9-deazahypoxanthines as pnp inhibitors
AU1183092A (en)	1992-09-07	Antalgic ointment
AU2168592A (en)	1993-01-08	Ltb4 synthesis inhibitors
AU1907492A (en)	1993-01-25	Valve
AU2159392A (en)	1993-01-12	Renin inhibiting compounds
AU1483892A (en)	1992-10-15	Container
AU1469592A (en)	1992-11-02	Pstn/pcn switching arrangement
AU1450692A (en)	1992-11-02	Stable memory operations
AU1707692A (en)	1992-12-03	Crate
AU3018492A (en)	1993-07-01	Novel thiazoles
AU5473694A (en)	1994-08-04	Nitrosamine inhibition
AU4717389A (en)	1990-06-28	Renin inhibitors