AU2003226537A8 - Modulators of the notch signalling pathway and uses thereof in medical treatment - Google Patents
Modulators of the notch signalling pathway and uses thereof in medical treatmentInfo
- Publication number
- AU2003226537A8 AU2003226537A8 AU2003226537A AU2003226537A AU2003226537A8 AU 2003226537 A8 AU2003226537 A8 AU 2003226537A8 AU 2003226537 A AU2003226537 A AU 2003226537A AU 2003226537 A AU2003226537 A AU 2003226537A AU 2003226537 A8 AU2003226537 A8 AU 2003226537A8
- Authority
- AU
- Australia
- Prior art keywords
- modulators
- medical treatment
- signalling pathway
- notch signalling
- notch
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
Applications Claiming Priority (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0207930.9 | 2002-04-05 | ||
GB0207929.1 | 2002-04-05 | ||
GB0207929A GB0207929D0 (en) | 2002-04-05 | 2002-04-05 | A method |
GB0207930A GB0207930D0 (en) | 2002-04-05 | 2002-04-05 | A method |
GB0212283A GB0212283D0 (en) | 2002-05-28 | 2002-05-28 | A method |
GB0212282A GB0212282D0 (en) | 2002-05-28 | 2002-05-28 | A method |
GB0212282.8 | 2002-05-28 | ||
GB0212283.6 | 2002-05-28 | ||
PCT/GB2002/003397 WO2003012441A1 (en) | 2001-07-25 | 2002-07-25 | Method for detecting modulators of notch signalling |
AUPCT/GB2002/003426 | 2002-07-25 | ||
AU2002317984 | 2002-07-25 | ||
PCT/GB2002/003426 WO2003011317A1 (en) | 2001-07-25 | 2002-07-25 | Modulators of notch signalling for use in immunotherapy |
GB0220913.8 | 2002-09-10 | ||
GB0220913A GB0220913D0 (en) | 2002-09-10 | 2002-09-10 | Medical treatment |
GB0220912.0 | 2002-09-10 | ||
GB0220912A GB0220912D0 (en) | 2002-09-10 | 2002-09-10 | Medical treatment |
GB0300234.2 | 2003-01-07 | ||
GB0300234A GB0300234D0 (en) | 2003-01-07 | 2003-01-07 | Medical treatment |
PCT/GB2003/001525 WO2003087159A2 (en) | 2002-04-05 | 2003-04-04 | Modulators of the notch signalling pathway and uses thereof in medical treatment |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2003226537A1 AU2003226537A1 (en) | 2003-10-27 |
AU2003226537A8 true AU2003226537A8 (en) | 2003-10-27 |
Family
ID=34109266
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2003226537A Abandoned AU2003226537A1 (en) | 2002-04-05 | 2003-04-04 | Modulators of the notch signalling pathway and uses thereof in medical treatment |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1492816A2 (en) |
JP (1) | JP2006506322A (en) |
AU (1) | AU2003226537A1 (en) |
WO (1) | WO2003087159A2 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0220658D0 (en) * | 2002-09-05 | 2002-10-16 | Lorantis Ltd | Immunotherapy |
CA2497226A1 (en) * | 2002-09-10 | 2004-03-25 | Lorantis Limited | Pharmaceutical compositions and medical treatments comprising notch ligand proteins |
WO2004060262A2 (en) * | 2003-01-07 | 2004-07-22 | Lorantis Limited | Modulators of notch signalling for use in immunotherpapy |
GB0300428D0 (en) * | 2003-01-09 | 2003-02-05 | Lorantis Ltd | Medical treatment |
WO2004064863A1 (en) * | 2003-01-23 | 2004-08-05 | Lorantis Limited | Treatment of autoimmune diseases using an activator for the notch signaling pathway |
WO2004083372A2 (en) * | 2003-03-21 | 2004-09-30 | Lorantis Limited | Modulators of the notch signaling pathway immobilized on particles for modifying immune responses |
GB0307472D0 (en) * | 2003-04-01 | 2003-05-07 | Lorantis Ltd | Medical treatment |
WO2004099379A2 (en) | 2003-05-02 | 2004-11-18 | Health Research, Inc. | Use of jag2 expression in diagnosis of plasma cell disorders |
JP2007512348A (en) * | 2003-11-26 | 2007-05-17 | ヘルス リサーチ インコーポレイテッド | Use of Notch pathway interference agents for the treatment of plasma cells |
WO2005111072A2 (en) | 2004-04-29 | 2005-11-24 | The Trustees Of Columbia University In The City Of New York | Notch-based fusion proteins and uses thereof |
WO2007027226A2 (en) * | 2005-04-28 | 2007-03-08 | Board Of Regents, The University Of Texas System | Systems and methods for the production of differentiated cells |
US7906116B2 (en) | 2005-09-01 | 2011-03-15 | Parkash Gill | Methods for using and identifying modulators of Delta-like 4 |
MX2010002053A (en) * | 2007-08-23 | 2010-07-28 | Univ Columbia | Compositions of humanized notch fusion proteins and methods of treatment. |
US9475855B2 (en) | 2008-08-22 | 2016-10-25 | The Trustees Of Columbia University In The City Of New York | Human Notch3 based fusion proteins as decoy inhibitors of Notch3 signaling |
TW201329105A (en) | 2011-10-04 | 2013-07-16 | Thr Trustees Of Columbia University In The City Of New York | Human Notch1 decoys |
JP2021514185A (en) * | 2018-02-14 | 2021-06-10 | サニーブルック リサーチ インスティチュート | Methods for generating cells of the T cell lineage |
CN112770754A (en) * | 2018-07-26 | 2021-05-07 | 加利福尼亚大学董事会 | Treatment of vascular obstruction by activation of Notch signaling |
AU2019329984A1 (en) * | 2018-08-28 | 2021-03-11 | Fred Hutchinson Cancer Center | Methods and compositions for adoptive T cell therapy incorporating induced notch signaling |
US20220195414A1 (en) * | 2019-04-08 | 2022-06-23 | Russell Biotech, Inc. | Improved Manufacturing Procedures for Cell Based Therapies |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2260365C (en) * | 1996-07-16 | 2004-08-10 | Asahi Kasei Kogyo Kabushiki Kaisha | Differentiation-suppressive polypeptide |
NZ335549A (en) * | 1996-11-07 | 2001-07-27 | Lorantis Ltd | Use of a notch-ligand for affecting infectious tolerance and in the manufacture of a medicament for immunotherapy |
WO2000025809A1 (en) * | 1998-10-30 | 2000-05-11 | Smith & Nephew Plc | Compositions comprising notch receptor manipulating agents |
JP2005518785A (en) * | 2001-11-14 | 2005-06-30 | ロランティス リミテッド | Internal medicine |
-
2003
- 2003-04-04 WO PCT/GB2003/001525 patent/WO2003087159A2/en active Application Filing
- 2003-04-04 EP EP03746366A patent/EP1492816A2/en not_active Ceased
- 2003-04-04 JP JP2003584114A patent/JP2006506322A/en active Pending
- 2003-04-04 AU AU2003226537A patent/AU2003226537A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1492816A2 (en) | 2005-01-05 |
AU2003226537A1 (en) | 2003-10-27 |
JP2006506322A (en) | 2006-02-23 |
WO2003087159A2 (en) | 2003-10-23 |
WO2003087159A3 (en) | 2004-02-05 |
WO2003087159A8 (en) | 2005-05-12 |
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MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |