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AU2003220320A1 - Ionization apparatus and method for mass spectrometer system - Google Patents

Ionization apparatus and method for mass spectrometer system

Info

Publication number
AU2003220320A1
AU2003220320A1 AU2003220320A AU2003220320A AU2003220320A1 AU 2003220320 A1 AU2003220320 A1 AU 2003220320A1 AU 2003220320 A AU2003220320 A AU 2003220320A AU 2003220320 A AU2003220320 A AU 2003220320A AU 2003220320 A1 AU2003220320 A1 AU 2003220320A1
Authority
AU
Australia
Prior art keywords
mass spectrometer
spectrometer system
ionization apparatus
ionization
mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003220320A
Other versions
AU2003220320A8 (en
Inventor
Pavel V. Bondarnko
Alexander A. Makarov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Finnigan LLC
Original Assignee
Thermo Finnigan LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/105,172 external-priority patent/US6707036B2/en
Application filed by Thermo Finnigan LLC filed Critical Thermo Finnigan LLC
Publication of AU2003220320A1 publication Critical patent/AU2003220320A1/en
Publication of AU2003220320A8 publication Critical patent/AU2003220320A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409—Sample holders or containers
    • H01J49/0418—Sample holders or containers for laser desorption, e.g. matrix-assisted laser desorption/ionisation [MALDI] plates or surface enhanced laser desorption/ionisation [SELDI] plates
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/067—Ion lenses, apertures, skimmers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]

Landscapes

  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AU2003220320A 2002-03-21 2003-03-14 Ionization apparatus and method for mass spectrometer system Abandoned AU2003220320A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10/105,172 2002-03-21
US10/105,172 US6707036B2 (en) 2002-03-21 2002-03-21 Ionization apparatus and method for mass spectrometer system
US10/341,621 2003-01-13
US10/341,621 US6707040B2 (en) 2002-03-21 2003-01-13 Ionization apparatus and method for mass spectrometer system
PCT/US2003/008041 WO2003081205A2 (en) 2002-03-21 2003-03-14 Ionization apparatus and method for mass spectrometer system

Publications (2)

Publication Number Publication Date
AU2003220320A1 true AU2003220320A1 (en) 2003-10-08
AU2003220320A8 AU2003220320A8 (en) 2003-10-08

Family

ID=29738740

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003220320A Abandoned AU2003220320A1 (en) 2002-03-21 2003-03-14 Ionization apparatus and method for mass spectrometer system

Country Status (4)

Country Link
EP (1) EP1492613A4 (en)
AU (1) AU2003220320A1 (en)
CA (1) CA2479872C (en)
WO (1) WO2003081205A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1574849B1 (en) * 2004-01-22 2012-09-26 Thermo Finnigan Llc Method and apparatus for FAIMS with a laser-based ionization source
US7700913B2 (en) * 2006-03-03 2010-04-20 Ionsense, Inc. Sampling system for use with surface ionization spectroscopy
JP2009539115A (en) 2006-05-26 2009-11-12 イオンセンス インコーポレイテッド Flexible open tube collection system for use in surface ionization technology
WO2009152945A2 (en) * 2008-05-29 2009-12-23 Universitaetsklinikum Muenster Ion source means for desorption / ionisation of analyte substances and method of desorbing / ionising of analyte subtances
US8207497B2 (en) 2009-05-08 2012-06-26 Ionsense, Inc. Sampling of confined spaces
US8822949B2 (en) 2011-02-05 2014-09-02 Ionsense Inc. Apparatus and method for thermal assisted desorption ionization systems
US8901488B1 (en) 2011-04-18 2014-12-02 Ionsense, Inc. Robust, rapid, secure sample manipulation before during and after ionization for a spectroscopy system
JP2014524121A (en) 2011-07-14 2014-09-18 ザ・ジョージ・ワシントン・ユニバーシティ Plume collimation for laser ablation and electrospray ionization mass spectrometry
GB2493179B (en) * 2011-07-26 2018-09-05 Kratos Analytical Ltd MALDI sample preparation methods and targets
US9337007B2 (en) 2014-06-15 2016-05-10 Ionsense, Inc. Apparatus and method for generating chemical signatures using differential desorption
US9899196B1 (en) 2016-01-12 2018-02-20 Jeol Usa, Inc. Dopant-assisted direct analysis in real time mass spectrometry
GB201705981D0 (en) * 2017-04-13 2017-05-31 Micromass Ltd MALDI target plate
US10636640B2 (en) 2017-07-06 2020-04-28 Ionsense, Inc. Apparatus and method for chemical phase sampling analysis
US10825673B2 (en) 2018-06-01 2020-11-03 Ionsense Inc. Apparatus and method for reducing matrix effects
GB201815676D0 (en) * 2018-09-26 2018-11-07 Micromass Ltd MALDI nozzle
CN114730694A (en) 2019-10-28 2022-07-08 埃昂森斯股份有限公司 Pulsating flow atmospheric real-time ionization
US11913861B2 (en) 2020-05-26 2024-02-27 Bruker Scientific Llc Electrostatic loading of powder samples for ionization

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3796872A (en) * 1970-12-18 1974-03-12 Ass Elect Ind Mass spectrometry
US5106583A (en) * 1989-03-08 1992-04-21 Applied Biosystems, Inc. Automated protein hydrolysis system
US5777324A (en) * 1996-09-19 1998-07-07 Sequenom, Inc. Method and apparatus for maldi analysis
AU1329899A (en) * 1997-12-05 1999-06-28 University Of British Columbia, The Method of analyzing ions in an apparatus including a time of flight mass spectrometer and a linear ion trap
US6331702B1 (en) * 1999-01-25 2001-12-18 University Of Manitoba Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use
CA2227806C (en) 1998-01-23 2006-07-18 University Of Manitoba Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use
US5965884A (en) * 1998-06-04 1999-10-12 The Regents Of The University Of California Atmospheric pressure matrix assisted laser desorption
US6849847B1 (en) 1998-06-12 2005-02-01 Agilent Technologies, Inc. Ambient pressure matrix-assisted laser desorption ionization (MALDI) apparatus and method of analysis
EP1181707B8 (en) * 1999-06-11 2011-04-27 DH Technologies Development Pte. Ltd. Maldi ion source with a pulse of gas, apparatus and method for determining molecular weight of labile molecules
CA2400644C (en) * 2000-02-18 2009-07-14 Board Of Trustees Of The Leland Stanford Junior University Apparatus and methods for parallel processing of micro-volume liquid reactions
JP2002175770A (en) * 2000-12-08 2002-06-21 Hitachi Ltd Sample chamber for gas exhaustion and circuit pattern forming device using the same
CA2448335C (en) * 2001-05-25 2010-01-26 Analytica Of Branford, Inc. Atmospheric and vacuum pressure maldi ion source
JP4772212B2 (en) 2001-05-31 2011-09-14 浜松ホトニクス株式会社 X-ray generator
US6683300B2 (en) * 2001-09-17 2004-01-27 Science & Engineering Services, Inc. Method and apparatus for mass spectrometry analysis of common analyte solutions

Also Published As

Publication number Publication date
CA2479872C (en) 2009-06-23
EP1492613A2 (en) 2005-01-05
WO2003081205A3 (en) 2003-12-18
CA2479872A1 (en) 2003-10-02
AU2003220320A8 (en) 2003-10-08
EP1492613A4 (en) 2009-12-16
WO2003081205A2 (en) 2003-10-02

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase