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AU2003299732A1 - Vectors for inducible rna interference - Google Patents

Vectors for inducible rna interference

Info

Publication number
AU2003299732A1
AU2003299732A1 AU2003299732A AU2003299732A AU2003299732A1 AU 2003299732 A1 AU2003299732 A1 AU 2003299732A1 AU 2003299732 A AU2003299732 A AU 2003299732A AU 2003299732 A AU2003299732 A AU 2003299732A AU 2003299732 A1 AU2003299732 A1 AU 2003299732A1
Authority
AU
Australia
Prior art keywords
vectors
rna interference
inducible rna
inducible
interference
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003299732A
Other languages
English (en)
Other versions
AU2003299732A8 (en
Inventor
Bijan Etemad-Moghadam
Joerg Heyer
Ronan C. O'hagan
William Rideout
William Winston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aveo Pharmaceuticals Inc
Original Assignee
Genpath Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genpath Pharmaceuticals Inc filed Critical Genpath Pharmaceuticals Inc
Publication of AU2003299732A8 publication Critical patent/AU2003299732A8/xx
Publication of AU2003299732A1 publication Critical patent/AU2003299732A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111General methods applicable to biologically active non-coding nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • C12N2310/111Antisense spanning the whole gene, or a large part of it
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/50Physical structure
    • C12N2310/53Physical structure partially self-complementary or closed
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00Production
    • C12N2330/30Production chemically synthesised

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2003299732A 2002-12-18 2003-12-18 Vectors for inducible rna interference Abandoned AU2003299732A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US43485602P 2002-12-18 2002-12-18
US60/434,856 2002-12-18
US49931303P 2003-08-28 2003-08-28
US60/499,313 2003-08-28
PCT/US2003/040548 WO2004056964A2 (fr) 2002-12-18 2003-12-18 Vecteurs pour l'interference arn inductible

Publications (2)

Publication Number Publication Date
AU2003299732A8 AU2003299732A8 (en) 2004-07-14
AU2003299732A1 true AU2003299732A1 (en) 2004-07-14

Family

ID=32685340

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003299732A Abandoned AU2003299732A1 (en) 2002-12-18 2003-12-18 Vectors for inducible rna interference

Country Status (2)

Country Link
AU (1) AU2003299732A1 (fr)
WO (1) WO2004056964A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8198077B2 (en) 2003-01-17 2012-06-12 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Inducible small RNA expression constructs for targeted gene silencing
FR2877674A1 (fr) * 2004-11-08 2006-05-12 Genoxay Sa Animaux modeles comprenant au moins un transgene et une sequence permettant l'expression controlee d'un rna interferant avec ledit transgene
NZ556635A (en) * 2004-12-22 2010-11-26 Genentech Inc Method for producing soluble multi-membrane-spanning proteins
US20090210955A1 (en) * 2005-06-09 2009-08-20 Artemis Pharmaceuticals Gmbh Shrna and sirna expression in a living organism under control of a codon-optimized repressor gene
EP1731607A1 (fr) * 2005-06-09 2006-12-13 ARTEMIS Pharmaceuticals GmbH Expression au sein d'un organisme vivant de shRNA et siRNA sous le contrôle d'un gène represseur de tétracycline à codons optimisés
US20080220471A1 (en) * 2005-07-27 2008-09-11 Genentech, Inc. Vectors and Methods Using Same
US20070113295A1 (en) * 2005-09-23 2007-05-17 California Institute Of Technology Gene blocking method
GB0602173D0 (en) 2006-02-03 2006-03-15 Avecia Ltd Expression system
EP3219799A1 (fr) * 2016-03-17 2017-09-20 IMBA-Institut für Molekulare Biotechnologie GmbH Expression sgrna crispr conditionnelle
CN110540995B (zh) * 2018-05-28 2023-01-10 南京农业大学 一种降低肌球蛋白-5蛋白及其在氰基丙烯酸酯类药物抗性治理中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004672A1 (fr) * 1992-08-26 1994-03-03 Dnx Corp. Systeme de regulation binaire, a mediation par un represseur, qui utilise la tetracydine pour controler l'expression de genes chez les animaux transgeniques
AU2002343792A1 (en) * 2001-11-28 2003-06-10 Center For Advanced Science And Technology Incubation, Ltd. siRNA EXPRESSION SYSTEM AND PROCESS FOR PRODUCING FUNCTIONAL GENE-KNOCKDOWN CELLS AND THE LIKE USING THE SAME
AU2003228301A1 (en) * 2002-03-06 2003-09-22 Rigel Pharmaceuticals, Inc. Novel method for delivery and intracellular synthesis of sirna molecules
EP1554386A2 (fr) * 2002-07-24 2005-07-20 Immusol Incorporated Systeme a un seul promoteur pour la production de cassettes d'expression d'arnsi et genotheque d'expression reposant sur l'utilisation d'un lieur en epingle a cheveux d'amorce de polymerase

Also Published As

Publication number Publication date
WO2004056964A3 (fr) 2004-10-14
WO2004056964A2 (fr) 2004-07-08
AU2003299732A8 (en) 2004-07-14

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase