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AU2003298171A1 - Protein complexes associated with app-processing - Google Patents

Protein complexes associated with app-processing

Info

Publication number
AU2003298171A1
AU2003298171A1 AU2003298171A AU2003298171A AU2003298171A1 AU 2003298171 A1 AU2003298171 A1 AU 2003298171A1 AU 2003298171 A AU2003298171 A AU 2003298171A AU 2003298171 A AU2003298171 A AU 2003298171A AU 2003298171 A1 AU2003298171 A1 AU 2003298171A1
Authority
AU
Australia
Prior art keywords
app
processing
protein complexes
complexes associated
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003298171A
Inventor
Tewis Bouwmeester
Gerard Drewes
Carsten Hopf
Gerard Joberty
Adele Rowley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cellzome GmbH
Original Assignee
Cellzome GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellzome GmbH filed Critical Cellzome GmbH
Publication of AU2003298171A1 publication Critical patent/AU2003298171A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003298171A 2003-09-05 2003-12-10 Protein complexes associated with app-processing Abandoned AU2003298171A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03019642 2003-09-05
EP03019642.2 2003-09-05
PCT/EP2003/013980 WO2005023858A1 (en) 2003-09-05 2003-12-10 Protein complexes associated with app-processing

Publications (1)

Publication Number Publication Date
AU2003298171A1 true AU2003298171A1 (en) 2005-03-29

Family

ID=34259147

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003298171A Abandoned AU2003298171A1 (en) 2003-09-05 2003-12-10 Protein complexes associated with app-processing

Country Status (2)

Country Link
AU (1) AU2003298171A1 (en)
WO (1) WO2005023858A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007028631A1 (en) * 2005-09-09 2007-03-15 H. Lundbeck A/S Genetic risk factor for neurodevelopmental disorders and their complications
WO2007096854A1 (en) * 2006-02-21 2007-08-30 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin Compositions and methods for modulating an immune response
WO2008027017A1 (en) * 2006-08-31 2008-03-06 Singapore Health Services Pte Ltd Modulation of neural activity and/or condition
US20100169988A1 (en) * 2006-12-06 2010-07-01 Bernhard Kohli Means and methods for isolating and determining novel targets for the treatment of neurodegenerative, neurological or neuropsychiatric disorders and compositions comprising the same
AT504553B1 (en) * 2006-12-06 2008-09-15 Jsw Res Forschungslabor Gmbh PEPTIDOMIMETICS MADE OF ROTATING AMINO ACIDS AND MEDICAMENTS CONTAINING THEREOF FOR THE TREATMENT OF NEURODEEGENERATIVE ILLNESSES
EP2481408A3 (en) 2007-03-01 2013-01-09 Probiodrug AG New use of glutaminyl cyclase inhibitors
US9656991B2 (en) 2007-04-18 2017-05-23 Probiodrug Ag Inhibitors of glutaminyl cyclase
EP2321417B1 (en) * 2008-08-20 2015-07-15 Brainco Biopharma, S.L. Stxbp1 as psychiatric biomarker in murine model system and its uses
CA2772488C (en) 2009-09-11 2018-04-17 Probiodrug Ag Heterocyclic derivatives as inhibitors of glutaminyl cyclase
JP6026284B2 (en) 2010-03-03 2016-11-16 プロビオドルグ エージー Inhibitors of glutaminyl cyclase
JP5688745B2 (en) 2010-03-10 2015-03-25 プロビオドルグ エージー Heterocyclic inhibitor of glutaminyl cyclase (QC, EC 2.3.2.5)
WO2011131748A2 (en) 2010-04-21 2011-10-27 Probiodrug Ag Novel inhibitors
DK2686313T3 (en) 2011-03-16 2016-05-02 Probiodrug Ag Benzimidazole derivatives as inhibitors of glutaminyl cyclase
US9522170B2 (en) * 2011-04-05 2016-12-20 Alphabeta Ab Methods of screening compounds for the fibril formation of Aβ peptides based on a decreased trimer/monomer ratio of a chaperone protein
JP6359159B2 (en) * 2017-07-25 2018-07-18 株式会社Ｍｃｂｉ Biomarker for cognitive dysfunction disease and method for detecting cognitive dysfunction disease using the biomarker
DK3461819T3 (en) 2017-09-29 2020-08-10 Probiodrug Ag GLUTAMINYL CYCLASE INHIBITORS

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837838A (en) * 1997-03-14 1998-11-17 The Burnham Institute Bax inhibitor proteins
US6383758B1 (en) * 1998-01-09 2002-05-07 The Governing Council Of The University Of Toronto Alzheimer's related proteins and methods of use
PT1105508E (en) * 1998-08-17 2003-01-31 Europ Lab Molekularbiolog METHOD OF PURIFICATION OF BIOMOLECULES OR PROTEIN COMPLEXES
GB0005895D0 (en) * 2000-03-10 2000-05-03 Glaxo Group Ltd Novel assay
US20020119155A1 (en) * 2000-10-17 2002-08-29 Myriad Genetics, Inc. Protein-protein interactions in neurodegenerative diseases
AU2003245987A1 (en) * 2002-06-26 2004-02-02 Cellzome Ag Components of the presenilin-complex

Also Published As

Publication number Publication date
WO2005023858A1 (en) 2005-03-17

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase