[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

AU2002364211A1 - Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents - Google Patents

Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents

Info

Publication number
AU2002364211A1
AU2002364211A1 AU2002364211A AU2002364211A AU2002364211A1 AU 2002364211 A1 AU2002364211 A1 AU 2002364211A1 AU 2002364211 A AU2002364211 A AU 2002364211A AU 2002364211 A AU2002364211 A AU 2002364211A AU 2002364211 A1 AU2002364211 A1 AU 2002364211A1
Authority
AU
Australia
Prior art keywords
prolylpeptidase
inducers
apoptosis
inhibitors
cancer treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002364211A
Inventor
Jacques Dumas
Robert Sibley
Jill Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharmaceuticals Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Publication of AU2002364211A1 publication Critical patent/AU2002364211A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002364211A 2001-12-21 2002-12-20 Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents Abandoned AU2002364211A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34304801P 2001-12-21 2001-12-21
US60/343,048 2001-12-21
PCT/US2002/041168 WO2003055890A1 (en) 2001-12-21 2002-12-20 Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents

Publications (1)

Publication Number Publication Date
AU2002364211A1 true AU2002364211A1 (en) 2003-07-15

Family

ID=23344458

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002364211A Abandoned AU2002364211A1 (en) 2001-12-21 2002-12-20 Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents

Country Status (2)

Country Link
AU (1) AU2002364211A1 (en)
WO (1) WO2003055890A1 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG156650A1 (en) * 2004-07-16 2009-11-26 Sunesis Pharmaceuticals Inc Thienopyrimidines useful as aurora kinase inhibitors
US7297704B2 (en) 2005-02-17 2007-11-20 Wyeth Cycloalkyfused indole, benzothiophene, benzofuran and idene derivatives
EP1847543A1 (en) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidines for the treatment of inflammatory diseases
UA93872C2 (en) 2006-04-19 2011-03-25 Бьорингер Ингельхайм Интернациональ Гмбх Dihydrothienopyrimidines for the treatment of inflammatory diseases
CA2702524A1 (en) 2007-10-19 2009-04-23 Boehringer Ingelheim International Gmbh Heterocycle-substituted piperazino-dihydrothienopyrimidines
EP2215093B1 (en) 2007-10-19 2011-12-14 Boehringer Ingelheim International GmbH Novel piperazino-dihydrothienopyrimidine derivatives
AU2008313660B2 (en) 2007-10-19 2013-11-07 Boehringer Ingelheim International Gmbh Substituted piperidino-dihydrothienopyrimidines
JP5489235B2 (en) * 2007-11-15 2014-05-14 ワイエム・バイオサイエンシズ・オーストラリア・ピーティーワイ・リミテッド N-containing heterocyclic compound
PL3330257T3 (en) 2011-04-08 2020-06-15 Janssen Sciences Ireland Unlimited Company Pyrimidine derivatives for the treatment of viral infections
US9802954B2 (en) 2011-08-24 2017-10-31 Boehringer Ingelheim International Gmbh Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
US20130059866A1 (en) 2011-08-24 2013-03-07 Boehringer Ingelheim International Gmbh Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
HRP20181497T1 (en) 2011-11-09 2018-11-30 Janssen Sciences Ireland Uc PURINE DERIVATIVES FOR TREATMENT OF Viral INFECTIONS
CA2874800C (en) 2012-07-13 2021-04-06 Janssen R&D Ireland Macrocyclic purines for the treatment of viral infections
ES2670513T3 (en) 2012-10-10 2018-05-30 Janssen Sciences Ireland Uc Pyrrolo [3,2-d] pyrimidine derivatives for the treatment of viral infections and other diseases
DK2925729T3 (en) 2012-11-16 2018-01-22 Janssen Sciences Ireland Uc HETEROCYCLIC SUBSTITUTED 2-AMINOQUINAZOLINE DERIVATIVES FOR TREATING VIRUS INFECTIONS
JP6404835B2 (en) 2013-02-21 2018-10-17 ヤンセン・サイエンシズ・アイルランド・ユーシー 2-Aminopyrimidine derivatives for the treatment of viral infections
EA202090547A3 (en) 2013-03-29 2020-12-30 Янссен Сайенсиз Айрлэнд Юси MACROCYCLIC DEASE-OXIPURINS FOR TREATMENT OF VIRAL INFECTIONS
CN103242341B (en) * 2013-04-19 2015-12-09 中国科学院广州生物医药与健康研究院 Thieno-2,4 substituted pyrimidines compounds and pharmaceutical composition thereof and application
AU2014270418B2 (en) 2013-05-24 2017-11-30 Janssen Sciences Ireland Uc Pyridone derivatives for the treatment of viral infections and further diseases
MX392130B (en) 2013-06-27 2025-03-21 Janssen Sciences Ireland Uc PYRROLO[3,2-D]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER DISEASES.
AU2014298540B2 (en) * 2013-07-30 2018-08-09 Janssen Sciences Ireland Uc Thieno[3,2-d]pyrimidines derivatives for the treatment of viral infections
US11053256B2 (en) 2016-07-01 2021-07-06 Janssen Sciences Ireland Unlimited Company Dihydropyranopyrimidines for the treatment of viral infections
CN107698603B (en) * 2016-08-09 2022-04-08 南京红云生物科技有限公司 Thienopyrimidine compound, its preparation method, pharmaceutical composition and its application
KR102450287B1 (en) 2016-09-29 2022-09-30 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 Pyrimidine prodrugs for treatment of viral infections and additional diseases
GB201700814D0 (en) 2017-01-17 2017-03-01 Liverpool School Tropical Medicine Compounds
CN109293519B (en) * 2017-07-25 2021-09-28 北京斯利安药业有限公司 Preparation method of tamoxifen citrate crystal form A
WO2019057806A1 (en) 2017-09-20 2019-03-28 Leo Pharma A/S Substituted dihydrothienopyrimidines and their use as phosphodiesterase inhibitors
CN109575045B (en) * 2017-09-28 2021-02-12 南京红云生物科技有限公司 Thienopyrimidine compound, preparation method thereof, medicinal composition and application thereof
FI3724196T3 (en) 2017-12-15 2023-01-31 Substituted azetidine dihydrothienopyridines and their use as phosphodiesterase inhibitors
TW202415645A (en) 2018-03-01 2024-04-16 愛爾蘭商健生科學愛爾蘭無限公司 2,4-diaminoquinazoline derivatives and medical uses thereof
KR20210146287A (en) * 2019-03-01 2021-12-03 레볼루션 메디슨즈, 인크. Bicyclic heteroaryl compounds and uses thereof
WO2022058896A1 (en) * 2020-09-15 2022-03-24 Cadila Healthcare Limited Inhibitors of low molecular weight protein tyrosine phosphatase for management of metabolic disorder
CN114105887B (en) * 2021-09-16 2023-12-01 沈阳药科大学 Aminopyrimidine derivative and preparation method and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470356A1 (en) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K New thieno [3,2-d] pyrimidines and process for their preparation
GB8912335D0 (en) * 1989-05-30 1989-07-12 Smithkline Beckman Intercredit Compounds
FI943798L (en) * 1992-02-19 1994-08-18 Pfizer Heterocyclic compounds intended to enhance antitumor activity
ID23978A (en) * 1997-11-11 2000-06-14 Pfizer Prod Inc TIENOPIRIMIDIN AND TIENOPIRIDIN DERIVES USED AS ANTI-CANCER SUBSTANCES
US5948911A (en) * 1998-11-20 1999-09-07 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to thienopyrimidine derivatives

Also Published As

Publication number Publication date
WO2003055890A1 (en) 2003-07-10

Similar Documents

Publication Publication Date Title
AU2002364211A1 (en) Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
AU2002361846A1 (en) Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
AU2002340168A1 (en) Treatment of prostate cancer by inhibitors of ncam2
AU2002328952A1 (en) Irinotecan for treatment of cancer
AU2003226301A1 (en) Method of treating cancer
AU2002339157A1 (en) Inhibitors of the notch signalling pathway for use in the treatment of cancer
AU2002367172A1 (en) 2,4-diamino-pyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
AU2003256847A1 (en) Method of treating cancer
AU2003243318A1 (en) Diarylurea compounds and derivatives as chk-1 inhibitors for the treatment of cancer
AU2002252456A1 (en) Combination treatment of pancreatic cancer
AU2002332430A1 (en) Methods of treating neuropilin-mediated diseases
AU2002252227A1 (en) Heterocyclic derivatives for the treatment of cancer and other proliferative diseases
AUPQ923100A0 (en) Treatment of prostate cancer
AU2001266838A1 (en) Inhibitors of matriptase for the treatment of cancer
MXPA03008582A (en) Agents and methods for treatment of cancer.
IL145397A0 (en) Compositions and methods for treatment of cancer
AU2002308642A1 (en) Methods for treating cancer
AU2001232060A1 (en) Use of cyp1b1 inhibitors for treating cancer
AU2001253836A1 (en) Method of treating cancer
AU2003280558A1 (en) Method for treatment of cancer
AU2003223538A1 (en) Methods for the treatment of cancer
AU2001241779A1 (en) Method of treatment of prostate cancer
AUPR644301A0 (en) Method and composition for treatment of cancer
AU2003296242A1 (en) Thia-epothilone derivatives for the treatment of cancer
AU2003231803A1 (en) Treatment of cancer with mefloquire

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase