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AU2002221978A1 - Dihydroceramide desaturase inhibitors. - Google Patents

Dihydroceramide desaturase inhibitors.

Info

Publication number
AU2002221978A1
AU2002221978A1 AU2002221978A AU2197802A AU2002221978A1 AU 2002221978 A1 AU2002221978 A1 AU 2002221978A1 AU 2002221978 A AU2002221978 A AU 2002221978A AU 2197802 A AU2197802 A AU 2197802A AU 2002221978 A1 AU2002221978 A1 AU 2002221978A1
Authority
AU
Australia
Prior art keywords
desaturase inhibitors
dihydroceramide desaturase
dihydroceramide
inhibitors
desaturase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002221978A
Inventor
Gemma Fabrias Domingo
Amadeo Llebaria Soldevila
Gemma Triola Guillem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Publication of AU2002221978A1 publication Critical patent/AU2002221978A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/26Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings other than six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/133Amines having hydroxy groups, e.g. sphingosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AU2002221978A 2000-12-19 2001-12-14 Dihydroceramide desaturase inhibitors. Abandoned AU2002221978A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200003045 2000-12-19
ES200003045A ES2170030B1 (en) 2000-12-19 2000-12-19 DIHYDROCERAMIDE DESATURASA INHIBITORS.
PCT/ES2001/000486 WO2002050018A1 (en) 2000-12-19 2001-12-14 Dihydroceramide desaturase inhibitors.

Publications (1)

Publication Number Publication Date
AU2002221978A1 true AU2002221978A1 (en) 2002-07-01

Family

ID=8496062

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002221978A Abandoned AU2002221978A1 (en) 2000-12-19 2001-12-14 Dihydroceramide desaturase inhibitors.

Country Status (4)

Country Link
EP (1) EP1354870A1 (en)
AU (1) AU2002221978A1 (en)
ES (1) ES2170030B1 (en)
WO (1) WO2002050018A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2233204B1 (en) * 2003-11-25 2006-08-01 Consejo Sup. Investig. Cientificas USE OF CYCLOPROPENYLPHINGOSINE DERIVATIVES FOR THE ELABORATION OF A PHARMACEUTICAL COMPOSITION MODULATOR OF CERAMIDASE ACTIVITY, AND ITS APPLICATIONS.
ES2255425B1 (en) * 2003-11-25 2007-08-16 Consejo Superior Investig. Cientificas PROCEDURE FOR OBTAINING COMPOUNDS DERIVED FROM CYCLOPROPENYLPHINGOSINE.
CA2575300A1 (en) * 2004-08-09 2006-02-16 Cellzome Ag Treatment of neurodegenerative diseases by the use of degs inhibitors
WO2012100835A1 (en) * 2011-01-28 2012-08-02 Laboratorios Del Dr. Esteve, S.A. Methods and compositions for the treatment of aids
KR20250057925A (en) 2018-01-11 2025-04-29 켄타우루스 테라퓨틱스 Inhibitors of dihydroceramide desaturase for treating disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395958A (en) * 1992-09-30 1995-03-07 Mitsubishi Kasei Corporation Cyclopropene derivatives

Also Published As

Publication number Publication date
ES2170030A1 (en) 2002-07-16
EP1354870A1 (en) 2003-10-22
ES2170030B1 (en) 2003-11-16
WO2002050018A1 (en) 2002-06-27

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