AU2002220857A1 - Particles for use in a pharmaceutical composition - Google Patents
Particles for use in a pharmaceutical compositionInfo
- Publication number
- AU2002220857A1 AU2002220857A1 AU2002220857A AU2085702A AU2002220857A1 AU 2002220857 A1 AU2002220857 A1 AU 2002220857A1 AU 2002220857 A AU2002220857 A AU 2002220857A AU 2085702 A AU2085702 A AU 2085702A AU 2002220857 A1 AU2002220857 A1 AU 2002220857A1
- Authority
- AU
- Australia
- Prior art keywords
- particles
- pharmaceutical composition
- dry powder
- additive material
- active particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention provides a method of making a composition for inhalation which includes the step of mixing particles of additive material having a diameter of not more than 2µm with active particles, wherein the additive material is suitable for promoting the dispersal of active particles upon aerosolisation of a dry powder in a dry powder inhaler.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0029261.5 | 2000-11-30 | ||
GB0029261A GB0029261D0 (en) | 2000-11-30 | 2000-11-30 | Method of making particles for use in a pharmaceutical composition |
GB0030946.8 | 2000-12-19 | ||
GB0030946A GB0030946D0 (en) | 2000-12-19 | 2000-12-19 | Method of making particles for use in a pharmaceutical composition |
GB0124009.2 | 2001-10-05 | ||
GB0124009A GB0124009D0 (en) | 2001-10-05 | 2001-10-05 | Particles for use in a pharmaceutical composition |
PCT/GB2001/005305 WO2002043700A2 (en) | 2000-11-30 | 2001-11-30 | Particles for use in a pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002220857A1 true AU2002220857A1 (en) | 2002-06-11 |
Family
ID=27255994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002220857A Abandoned AU2002220857A1 (en) | 2000-11-30 | 2001-11-30 | Particles for use in a pharmaceutical composition |
Country Status (8)
Country | Link |
---|---|
US (3) | US8580306B2 (en) |
EP (3) | EP1337239B2 (en) |
AT (1) | ATE446085T1 (en) |
AU (1) | AU2002220857A1 (en) |
DE (1) | DE60140268D1 (en) |
ES (2) | ES2689704T3 (en) |
PT (1) | PT1337239E (en) |
WO (1) | WO2002043700A2 (en) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9515182D0 (en) * | 1995-07-24 | 1995-09-20 | Co Ordinated Drug Dev | Improvements in and relating to powders for use in dry powder inhalers |
GB0009469D0 (en) * | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formalities for use in inhaler devices |
WO2002000197A1 (en) | 2000-06-27 | 2002-01-03 | Vectura Limited | Method of making particles for use in a pharmaceutical composition |
ES2689704T3 (en) * | 2000-11-30 | 2018-11-15 | Vectura Limited | Particles for use in a pharmaceutical composition |
PT2283818T (en) | 2000-11-30 | 2017-10-09 | Vectura Ltd | Method of making particles for use in a pharmaceutical composition |
AU2002222115B2 (en) † | 2000-11-30 | 2006-09-28 | Vectura Limited | Method of making particles for use in a pharmaceutical composition |
US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
US20060147389A1 (en) * | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
US20120321717A1 (en) * | 2003-04-14 | 2012-12-20 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
GB0321607D0 (en) * | 2003-09-15 | 2003-10-15 | Vectura Ltd | Manufacture of pharmaceutical compositions |
GB0425758D0 (en) | 2004-11-23 | 2004-12-22 | Vectura Ltd | Preparation of pharmaceutical compositions |
GB0426301D0 (en) * | 2004-11-30 | 2004-12-29 | Vectura Ltd | Pharmaceutical formulations |
GB0525254D0 (en) | 2005-12-12 | 2006-01-18 | Jagotec Ag | Powder compositions for inhalation |
CA2631492A1 (en) * | 2005-12-15 | 2007-06-21 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for oral administration |
GB0712316D0 (en) * | 2007-06-26 | 2007-08-01 | Entripneur Ltd | A novel powder and its method of manufacture |
WO2009142852A2 (en) | 2008-05-22 | 2009-11-26 | 3M Innovative Properties Company | Process for manufacturing flowable powder drug compositions |
EP2309978B1 (en) | 2008-06-26 | 2018-12-26 | 3M Innovative Properties Company | Dry powder pharmaceutical compositions for pulmonary administration, and methods of manufacturing thereof |
EP2309984B1 (en) | 2008-07-02 | 2018-04-11 | 3M Innovative Properties Company | Method of making a dry powder pharmaceutical composition |
PT2400950T (en) | 2009-02-26 | 2019-08-29 | Glaxo Group Ltd | Pharmaceutical formulations comprising 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol |
GB0921075D0 (en) | 2009-12-01 | 2010-01-13 | Glaxo Group Ltd | Novel combination of the therapeutic agents |
CN102655855B (en) * | 2009-12-14 | 2015-03-11 | 奇斯药制品公司 | Antibiotic microparticles for inhalation |
RU2666963C2 (en) | 2012-04-13 | 2018-09-13 | Глаксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед | Aggregated particles |
JP5087182B1 (en) * | 2012-06-13 | 2012-11-28 | クリニプロ株式会社 | Method for producing inhalable powder |
US20170333359A1 (en) * | 2014-10-20 | 2017-11-23 | Rx Analytic, Inc | A drug-containing micro particle |
US10806770B2 (en) | 2014-10-31 | 2020-10-20 | Monash University | Powder formulation |
EP3340982B1 (en) | 2015-08-26 | 2021-12-15 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
AR106018A1 (en) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | ARYL, HETEROARYL AND HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS |
CA3029262A1 (en) | 2016-06-27 | 2018-01-04 | Achillion Pharmaceuticals, Inc. | Quinazoline and indole compounds to treat medical disorders |
EP3589628A4 (en) | 2017-03-01 | 2021-03-31 | Achillion Pharmaceuticals, Inc. | Aryl, heteroary, and heterocyclic pharmaceutical compounds for treatment of medical disorders |
CA3077421A1 (en) * | 2017-10-02 | 2019-04-11 | Board Of Regents, The University Of Texas System | Inhalable composition of clofazimine and methods of use thereof |
KR20210018199A (en) | 2018-03-26 | 2021-02-17 | 씨4 테라퓨틱스, 인코포레이티드 | Cerevlon binder for decomposition of Ikaros |
JP7538113B2 (en) | 2018-08-20 | 2024-08-21 | アキリオン ファーマシューティカルズ,インコーポレーテッド | Pharmaceutical compounds for the treatment of medical disorders of complement factor D - Patents.com |
EP3866773B1 (en) | 2018-10-16 | 2024-08-28 | Georgia State University Research Foundation, Inc. | Carbon monoxide prodrugs for the treatment of medical disorders |
CA3165309A1 (en) | 2020-03-05 | 2021-09-10 | Christopher G. Nasveschuk | Compounds for targeted degradation of brd9 |
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GB124009A (en) | 1918-01-12 | 1919-03-12 | Walter Edward Kimber | Improvements in and connected with the Manufacture of Tools for Turning, Planing, Boring and similar purposes. |
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GB0009469D0 (en) | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formalities for use in inhaler devices |
GB0009468D0 (en) | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formulations for use in inhaler devices |
PE20011227A1 (en) | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | PHARMACEUTICAL FORMULATIONS FOR DRY POWDER INHALERS IN THE FORM OF HARD AGGLOMERATES |
WO2002000197A1 (en) | 2000-06-27 | 2002-01-03 | Vectura Limited | Method of making particles for use in a pharmaceutical composition |
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ES2689704T3 (en) * | 2000-11-30 | 2018-11-15 | Vectura Limited | Particles for use in a pharmaceutical composition |
PT2283818T (en) * | 2000-11-30 | 2017-10-09 | Vectura Ltd | Method of making particles for use in a pharmaceutical composition |
GB0124009D0 (en) | 2001-10-05 | 2001-11-28 | Vectura Ltd | Particles for use in a pharmaceutical composition |
US20060147389A1 (en) | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
US20060292081A1 (en) | 2003-09-15 | 2006-12-28 | Vectura Limited | Methods for preparing pharmaceutical compositions |
GB0321607D0 (en) | 2003-09-15 | 2003-10-15 | Vectura Ltd | Manufacture of pharmaceutical compositions |
-
2001
- 2001-11-30 ES ES09173566.2T patent/ES2689704T3/en not_active Expired - Lifetime
- 2001-11-30 AT AT01998327T patent/ATE446085T1/en active
- 2001-11-30 EP EP01998327.9A patent/EP1337239B2/en not_active Expired - Lifetime
- 2001-11-30 WO PCT/GB2001/005305 patent/WO2002043700A2/en not_active Application Discontinuation
- 2001-11-30 EP EP10185079A patent/EP2292212A3/en not_active Withdrawn
- 2001-11-30 DE DE60140268T patent/DE60140268D1/en not_active Expired - Lifetime
- 2001-11-30 ES ES01998327.9T patent/ES2334642T5/en not_active Expired - Lifetime
- 2001-11-30 US US10/433,135 patent/US8580306B2/en not_active Expired - Lifetime
- 2001-11-30 AU AU2002220857A patent/AU2002220857A1/en not_active Abandoned
- 2001-11-30 PT PT01998327T patent/PT1337239E/en unknown
- 2001-11-30 EP EP09173566.2A patent/EP2168571B1/en not_active Expired - Lifetime
-
2013
- 2013-10-10 US US14/050,819 patent/US9585839B2/en not_active Expired - Lifetime
-
2017
- 2017-02-15 US US15/433,106 patent/US10238601B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20040071635A1 (en) | 2004-04-15 |
US10238601B2 (en) | 2019-03-26 |
ATE446085T1 (en) | 2009-11-15 |
EP1337239B2 (en) | 2015-11-25 |
ES2689704T3 (en) | 2018-11-15 |
DE60140268D1 (en) | 2009-12-03 |
WO2002043700A3 (en) | 2002-10-24 |
EP2292212A2 (en) | 2011-03-09 |
EP1337239B1 (en) | 2009-10-21 |
PT1337239E (en) | 2010-01-26 |
US20170216202A1 (en) | 2017-08-03 |
ES2334642T3 (en) | 2010-03-15 |
WO2002043700A2 (en) | 2002-06-06 |
ES2334642T5 (en) | 2016-03-07 |
EP2168571B1 (en) | 2018-08-22 |
EP2292212A3 (en) | 2012-08-08 |
EP2168571A3 (en) | 2011-11-16 |
US8580306B2 (en) | 2013-11-12 |
EP2168571A2 (en) | 2010-03-31 |
EP1337239A2 (en) | 2003-08-27 |
US20140037737A1 (en) | 2014-02-06 |
US9585839B2 (en) | 2017-03-07 |
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