[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

AU2001236177A1 - T cell receptor libraries - Google Patents

T cell receptor libraries

Info

Publication number
AU2001236177A1
AU2001236177A1 AU2001236177A AU3617701A AU2001236177A1 AU 2001236177 A1 AU2001236177 A1 AU 2001236177A1 AU 2001236177 A AU2001236177 A AU 2001236177A AU 3617701 A AU3617701 A AU 3617701A AU 2001236177 A1 AU2001236177 A1 AU 2001236177A1
Authority
AU
Australia
Prior art keywords
cell receptor
receptor libraries
libraries
cell
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001236177A
Inventor
Helmut Wilhelmus Hubertus Gerardus Kessels
Antonius Nicolaas Maria Schumacher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Het Nederlands Kanker Instituut
Original Assignee
HET NL KANKER I
Het Nederlands Kanker Instituut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HET NL KANKER I, Het Nederlands Kanker Instituut filed Critical HET NL KANKER I
Publication of AU2001236177A1 publication Critical patent/AU2001236177A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2001236177A 2000-01-13 2001-01-15 T cell receptor libraries Abandoned AU2001236177A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00200110 2000-01-13
EP00200110A EP1118661A1 (en) 2000-01-13 2000-01-13 T cell receptor libraries
PCT/NL2001/000021 WO2001055366A1 (en) 2000-01-13 2001-01-15 T cell receptor libraries

Publications (1)

Publication Number Publication Date
AU2001236177A1 true AU2001236177A1 (en) 2001-08-07

Family

ID=8170906

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001236177A Abandoned AU2001236177A1 (en) 2000-01-13 2001-01-15 T cell receptor libraries

Country Status (5)

Country Link
US (1) US20030082719A1 (en)
EP (2) EP1118661A1 (en)
AU (1) AU2001236177A1 (en)
CA (1) CA2399109A1 (en)
WO (1) WO2001055366A1 (en)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1259601A2 (en) * 2000-02-22 2002-11-27 Ahuva Nissim Chimeric and tcr phage display libraries, chimeric and tcr reagents and methods of use thereof
WO2004044004A2 (en) 2002-11-09 2004-05-27 Avidex Limited T cell receptor display
AU2004289316B2 (en) 2003-11-10 2011-03-31 Altor Bioscience Corporation Soluble TCR molecules and methods of use
GB0328363D0 (en) 2003-12-06 2004-01-14 Imp College Innovations Ltd Therapeutically useful molecules
GB0411125D0 (en) * 2004-05-19 2004-06-23 Avidex Ltd Method of improving T-cell receptors
JP4972549B2 (en) * 2004-05-19 2012-07-11 イムノコア リミテッド Methods for improving T cell receptors
EP1791865B1 (en) 2004-06-29 2010-07-28 Immunocore Ltd. Cells expressing a modified t cell receptor
WO2006036445A2 (en) 2004-09-24 2006-04-06 Trustees Of Dartmouth College Chimeric nk receptor and methods for treating cancer
ATE414718T1 (en) 2005-01-05 2008-12-15 F Star Biotech Forsch & Entw SYNTHETIC IMMUNOGLOBULIN DOMAINS WITH BINDING PROPERTIES MODIFIED IN REGIONS OF THE MOLECULE DIFFERENT FROM THE AREAS DETERMINING COMPLEMENTARITY
US20080015139A1 (en) * 2006-04-05 2008-01-17 Mathias Lichterfeld Soluble virus-specific T-cell receptor compositions
AT503861B1 (en) 2006-07-05 2008-06-15 F Star Biotech Forsch & Entw METHOD FOR MANIPULATING T-CELL RECEPTORS
AT503889B1 (en) 2006-07-05 2011-12-15 Star Biotechnologische Forschungs Und Entwicklungsges M B H F MULTIVALENT IMMUNE LOBULINE
US8921279B2 (en) 2007-06-26 2014-12-30 F-Star Biotechnologische Forschungs—und Entwicklungsges. m.b.H Display of binding agents
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
EP2596023A4 (en) * 2010-07-20 2014-03-05 Beth Israel Hospital Compositions and methods featuring il-6 and il-21 antagonists
WO2013033626A2 (en) 2011-08-31 2013-03-07 Trustees Of Dartmouth College Nkp30 receptor targeted therapeutics
EP2844743B1 (en) 2012-05-03 2021-01-13 Fred Hutchinson Cancer Research Center Enhanced affinity t cell receptors and methods for making the same
CN104395344B (en) 2012-05-07 2019-08-13 达特茅斯大学理事会 Anti- B7-H6 antibody, fusion protein and its application method
EP3636664A1 (en) * 2012-07-27 2020-04-15 The Board of Trustees of the University of Illinois Engineering t-cell receptors
US9587237B2 (en) 2013-03-14 2017-03-07 Elwha Llc Compositions, methods, and computer systems related to making and administering modified T cells
US9499855B2 (en) 2013-03-14 2016-11-22 Elwha Llc Compositions, methods, and computer systems related to making and administering modified T cells
WO2014159435A1 (en) * 2013-03-14 2014-10-02 Elwha Llc Compositions, methods, and computer systems related to making and administering modified t cells
SG11201600853UA (en) 2013-08-05 2016-03-30 Twist Bioscience Corp De novo synthesized gene libraries
US10669304B2 (en) 2015-02-04 2020-06-02 Twist Bioscience Corporation Methods and devices for de novo oligonucleic acid assembly
WO2016172377A1 (en) 2015-04-21 2016-10-27 Twist Bioscience Corporation Devices and methods for oligonucleic acid library synthesis
EP3303591B1 (en) 2015-06-01 2019-04-03 Medigene Immunotherapies GmbH T cell receptor library
EA201792661A1 (en) 2015-06-01 2018-05-31 Медиджин Иммьюнотерапиз Гмбх METHOD OF OBTAINING ANTIBODIES AGAINST T-CELL RECEPTOR
KR20180050411A (en) 2015-09-18 2018-05-14 트위스트 바이오사이언스 코포레이션 Oligonucleotide mutant library and its synthesis
KR20180058772A (en) 2015-09-22 2018-06-01 트위스트 바이오사이언스 코포레이션 Flexible substrate for nucleic acid synthesis
CA3006867A1 (en) 2015-12-01 2017-06-08 Twist Bioscience Corporation Functionalized surfaces and preparation thereof
TWI772282B (en) 2015-12-23 2022-08-01 德商梅迪基因免疫治療公司 Dendritic cell composition
KR20180131557A (en) 2016-04-05 2018-12-10 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 Inhibition of TGF beta in immunotherapy
GB2568444A (en) 2016-08-22 2019-05-15 Twist Bioscience Corp De novo synthesized nucleic acid libraries
EP3516528A4 (en) 2016-09-21 2020-06-24 Twist Bioscience Corporation Nucleic acid based data storage
WO2018112426A1 (en) * 2016-12-16 2018-06-21 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
JP2020508661A (en) 2017-02-22 2020-03-26 ツイスト バイオサイエンス コーポレーション Nucleic acid based data storage
WO2018170169A1 (en) 2017-03-15 2018-09-20 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
WO2018231864A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
IL271205B1 (en) 2017-06-12 2024-10-01 Twist Bioscience Corp Methods for seamless nucleic acid assembly
JP2020536504A (en) 2017-09-11 2020-12-17 ツイスト バイオサイエンス コーポレーション GPCR-coupled protein and its synthesis
US10894242B2 (en) 2017-10-20 2021-01-19 Twist Bioscience Corporation Heated nanowells for polynucleotide synthesis
SG11202006460SA (en) 2018-01-04 2020-08-28 Twist Bioscience Corp Dna-based digital information storage
SG11202011467RA (en) 2018-05-18 2020-12-30 Twist Bioscience Corp Polynucleotides, reagents, and methods for nucleic acid hybridization
WO2020018715A1 (en) 2018-07-17 2020-01-23 Massachusetts Institute Of Technology Soluble multimeric immunoglobulin-scaffold based fusion proteins and uses thereof
EP3847266A1 (en) 2018-09-05 2021-07-14 GlaxoSmithKline Intellectual Property Development Ltd T cell modification
US11492728B2 (en) 2019-02-26 2022-11-08 Twist Bioscience Corporation Variant nucleic acid libraries for antibody optimization
AU2020229349A1 (en) 2019-02-26 2021-10-14 Twist Bioscience Corporation Variant nucleic acid libraries for GLP1 receptor
CA3144644A1 (en) 2019-06-21 2020-12-24 Twist Bioscience Corporation Barcode-based nucleic acid sequence assembly
EP4034566A4 (en) 2019-09-23 2024-01-24 Twist Bioscience Corporation Variant nucleic acid libraries for crth2
TW202204379A (en) * 2020-06-08 2022-02-01 中央研究院 Method for selecting antibody fragments, recombinant antibodies produced therefrom, and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698426A (en) * 1990-09-28 1997-12-16 Ixsys, Incorporated Surface expression libraries of heteromeric receptors
US5635363A (en) * 1995-02-28 1997-06-03 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for the detection, quantitation and purification of antigen-specific T cells
DE69723230T2 (en) * 1996-01-17 2004-05-27 Imperial College Innovations Ltd. IMMUNOTHERAPY USING CYTOTOXIC T LYMPHOCYTES (CTL)
DE19625191A1 (en) * 1996-06-24 1998-01-02 Boehringer Mannheim Gmbh Renal carcinoma-specific T cells
EP0977886A4 (en) * 1997-03-07 2002-10-23 Sunol Molecular Corp Fusion proteins comprising bacteriophage coat protein and a single-chain t cell receptor
US6759243B2 (en) * 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
FR2778669B1 (en) * 1998-05-14 2002-06-14 Centre Nat Rech Scient PROCESS FOR EXPRESSING A COMPLEX FORMED OF AT LEAST ONE PRODUCT OF THE MAJOR HISTOCOMPATIBILITY COMPLEX AND A PEPTIDE IN A PHAGE, PHAGES AND COMPLEXES OBTAINED THEREFROM AND THEIR APPLICATIONS
NZ507887A (en) * 1998-05-19 2002-12-20 Avidex Ltd Soluble T cell receptor

Also Published As

Publication number Publication date
EP1118661A1 (en) 2001-07-25
EP1246910A1 (en) 2002-10-09
WO2001055366A9 (en) 2002-07-18
US20030082719A1 (en) 2003-05-01
CA2399109A1 (en) 2001-08-02
WO2001055366A1 (en) 2001-08-02

Similar Documents

Publication Publication Date Title
AU2001236177A1 (en) T cell receptor libraries
AU2002211542A1 (en) Combinatorial synthesis system
AU2001228665A1 (en) Toll-like receptor
AU2001249323A1 (en) Nanocylinder arrays
AUPQ910500A0 (en) Support means
AU5163600A (en) Mass storage technology
AU3223100A (en) Proteomic interaction arrays
AU2001262855A1 (en) Support structure
AU1132601A (en) Feature interactions
AUPQ529000A0 (en) Toner characterization cell
AU2001231073A1 (en) Planar loudspeaker for cabin-like environment
AU6179400A (en) Multi-photodetector unit cell
AU1936201A (en) Protein-protein interactions
AU1551901A (en) Semaphorin receptor
AU7593800A (en) Small library works-in-a-drawer
AU2000267447A1 (en) Microphone array system
AU7318700A (en) Novel transaldolase gene
AU6642900A (en) Improved materials for mycoculture
AU2001223882A1 (en) Receptor
AUPQ563400A0 (en) Novel receptor
AU6302100A (en) Domed construction
AU2002230895A1 (en) Protein-protein interactions
AU2001286053A1 (en) Cell assays
AU2002215747A1 (en) Pixel cell architecture
WO2001029756A8 (en) Autogrid analysis