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AU2001233064A1 - Methods for inhibiting smooth muscle cell proliferation - Google Patents

Methods for inhibiting smooth muscle cell proliferation

Info

Publication number
AU2001233064A1
AU2001233064A1 AU2001233064A AU3306401A AU2001233064A1 AU 2001233064 A1 AU2001233064 A1 AU 2001233064A1 AU 2001233064 A AU2001233064 A AU 2001233064A AU 3306401 A AU3306401 A AU 3306401A AU 2001233064 A1 AU2001233064 A1 AU 2001233064A1
Authority
AU
Australia
Prior art keywords
methods
cell proliferation
smooth muscle
muscle cell
inhibiting smooth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001233064A
Inventor
Gere S. Dizerega
Kathleen E Rodgers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Southern California USC
Original Assignee
University of Southern California USC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Southern California USC filed Critical University of Southern California USC
Publication of AU2001233064A1 publication Critical patent/AU2001233064A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/085—Angiotensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001233064A 2000-01-27 2001-01-26 Methods for inhibiting smooth muscle cell proliferation Abandoned AU2001233064A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17842300P 2000-01-27 2000-01-27
US60/178,423 2000-01-27
PCT/US2001/002768 WO2001055176A2 (en) 2000-01-27 2001-01-26 Methods for inhibiting smooth muscle cell proliferation

Publications (1)

Publication Number Publication Date
AU2001233064A1 true AU2001233064A1 (en) 2001-08-07

Family

ID=22652502

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001233064A Abandoned AU2001233064A1 (en) 2000-01-27 2001-01-26 Methods for inhibiting smooth muscle cell proliferation

Country Status (3)

Country Link
US (1) US20020049162A1 (en)
AU (1) AU2001233064A1 (en)
WO (1) WO2001055176A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0105509B8 (en) * 2001-11-05 2021-05-25 Univ Minas Gerais formulations of the angiotensin- (1-7) peptide using cyclodextrins, liposomes and the plga polymer
CN1747734A (en) * 2003-02-07 2006-03-15 贝林格尔·英格海姆国际有限公司 Use of dipyridamole or mopidamole for treatment and prevention of mmp-9-dependent disorders
EP1833970A2 (en) 2004-12-22 2007-09-19 Genentech, Inc. Methods for producing soluble multi-membrane-spanning proteins
WO2006078223A1 (en) * 2005-01-18 2006-07-27 National University Of Singapore Angiotensin i derivatives
BRPI0503122A (en) * 2005-05-30 2007-05-02 Univ Minas Gerais angiotensin- (1-7) [ang- (1-7)] peptide pharmaceutical compositions and their analogs, agonists and antagonists using cyclodextrins, their derivatives, and biodegradable polymers and / or derived products for use in controlling their functions of the reproductive system
AT508569A1 (en) * 2009-07-23 2011-02-15 Affiris Ag PHARMACEUTICAL COMPOUND
US20170218040A1 (en) 2016-02-02 2017-08-03 Julio A. Camarero Palao Proteolically resistant cyclotides with angiotensin 1-7 like activity
EP4371556A1 (en) 2022-11-15 2024-05-22 Explicat Pharma GmbH Angiotensin(1-7) pharmaceutical compositions for inhalation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA934536B (en) * 1992-06-24 1994-02-03 Univ Washington Angiotensin IV peptides and receptors
SG68529A1 (en) * 1995-05-25 1999-11-16 Univ Singapore The use of des-aspartate-angiotensin i (agr-val-tyr-ile-his-pro-phe-his-leu) as an anti-cardiac hypertrophic agent
US5834432A (en) * 1995-06-06 1998-11-10 The University Of Southern California Use of angiotensin II Type 2 receptor agonists in tissue repair
SG92610A1 (en) * 1997-10-24 2002-11-19 Univ Singapore The use of des-aspartate-angiotensin i as an agent for the treatment and prevention of neointima formation, restenosis, and arteriosclerosis
ATE268782T1 (en) * 1997-12-12 2004-06-15 Univ Southern California COMPOSITIONS FOR WOUND HEALING

Also Published As

Publication number Publication date
WO2001055176A2 (en) 2001-08-02
WO2001055176A3 (en) 2002-07-25
US20020049162A1 (en) 2002-04-25

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