AU2001231090A1 - Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage - Google Patents
Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavageInfo
- Publication number
- AU2001231090A1 AU2001231090A1 AU2001231090A AU3109001A AU2001231090A1 AU 2001231090 A1 AU2001231090 A1 AU 2001231090A1 AU 2001231090 A AU2001231090 A AU 2001231090A AU 3109001 A AU3109001 A AU 3109001A AU 2001231090 A1 AU2001231090 A1 AU 2001231090A1
- Authority
- AU
- Australia
- Prior art keywords
- bioactivated
- magnetic resonance
- resonance imaging
- contrast agents
- enzymatic cleavage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000003776 cleavage reaction Methods 0.000 title 1
- 239000002872 contrast media Substances 0.000 title 1
- 230000002255 enzymatic effect Effects 0.000 title 1
- 238000002595 magnetic resonance imaging Methods 0.000 title 1
- 230000007017 scission Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
- A61K49/143—Peptides, e.g. proteins the protein being an albumin, e.g. HSA, BSA, ovalbumin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17758000P | 2000-01-22 | 2000-01-22 | |
US60177580 | 2000-01-22 | ||
PCT/US2001/002221 WO2001052906A2 (en) | 2000-01-22 | 2001-01-22 | Magnetic resonance imaging using contrast agents prodrugs bioactivated by enzymatic cleavage |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001231090A1 true AU2001231090A1 (en) | 2001-07-31 |
Family
ID=22649156
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001231090A Abandoned AU2001231090A1 (en) | 2000-01-22 | 2001-01-22 | Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1251876A2 (en) |
JP (1) | JP2003520255A (en) |
AU (1) | AU2001231090A1 (en) |
WO (1) | WO2001052906A2 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6713045B1 (en) | 1995-06-02 | 2004-03-30 | Research Corporation Technologies, Inc. | Targeted magnetic resonance imaging agents for the detection of physiological processes |
EP1032430A2 (en) | 1997-11-17 | 2000-09-06 | Research Corporation Technologies, Inc. | Magnetic resonance imaging agents for the detection of physiological agents |
US6673333B1 (en) | 2000-05-04 | 2004-01-06 | Research Corporation Technologies, Inc. | Functional MRI agents for cancer imaging |
US6656450B2 (en) | 2000-07-17 | 2003-12-02 | California Institute Of Technology, Inc. | Macrocyclic magnetic resonance imaging contrast agents |
TWI284539B (en) * | 2001-07-30 | 2007-08-01 | Epix Pharm Inc | A method for making a magnetic resonance (MR) imaging agent, a MR imaging contrast agent, a method for altering stability of a peptide and a modified peptide |
AU2003251436A1 (en) * | 2002-07-22 | 2004-02-09 | Bracco Imaging S.P.A. | Procedures of cellular labelling with paramagnetic complexes for mri applications |
EP3101012A1 (en) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | New gadolinium chelate compounds for use in magnetic resonance imaging |
US10975060B2 (en) | 2016-11-28 | 2021-04-13 | Bayer Pharma Aktiengesellschaft | High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging |
KR20210095168A (en) | 2018-11-23 | 2021-07-30 | 바이엘 악티엔게젤샤프트 | Formulation of Contrast Media and Method for Preparing Same |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0037388B1 (en) * | 1980-03-31 | 1984-12-12 | Institut International De Pathologie Cellulaire Et Moleculaire | Pharmaceutical forms, their preparation and compositions containing the same |
US5707605A (en) * | 1995-06-02 | 1998-01-13 | Research Corporation Technologies | Magnetic resonance imaging agents for the detection of physiological agents |
US5935824A (en) * | 1996-01-31 | 1999-08-10 | Technologene, Inc. | Protein expression system |
ES2217408T3 (en) * | 1996-04-01 | 2004-11-01 | Epix Medical, Inc. | CONTRACT DIAGNOSTIC AGENTS FOR THE FORMATION OF BIOACTIVE IMAGES. |
DE69819925T2 (en) * | 1997-10-02 | 2004-09-02 | Epix Medical, Inc., Cambridge | Contrast-enhanced diagnostic image generation method for monitoring therapeutic interventions |
CA2307332C (en) * | 1997-10-27 | 2008-09-16 | California Institute Of Technology | Magnetic resonance imaging agents for the delivery of therapeutic agents |
EP1032430A2 (en) * | 1997-11-17 | 2000-09-06 | Research Corporation Technologies, Inc. | Magnetic resonance imaging agents for the detection of physiological agents |
-
2001
- 2001-01-22 EP EP01903247A patent/EP1251876A2/en not_active Withdrawn
- 2001-01-22 JP JP2001552953A patent/JP2003520255A/en not_active Withdrawn
- 2001-01-22 WO PCT/US2001/002221 patent/WO2001052906A2/en not_active Application Discontinuation
- 2001-01-22 AU AU2001231090A patent/AU2001231090A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2001052906A3 (en) | 2002-01-24 |
EP1251876A2 (en) | 2002-10-30 |
WO2001052906A2 (en) | 2001-07-26 |
JP2003520255A (en) | 2003-07-02 |
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