AU2001286976A1 - Novel autoinducer molecules and uses therefor - Google Patents
Novel autoinducer molecules and uses thereforInfo
- Publication number
- AU2001286976A1 AU2001286976A1 AU2001286976A AU8697601A AU2001286976A1 AU 2001286976 A1 AU2001286976 A1 AU 2001286976A1 AU 2001286976 A AU2001286976 A AU 2001286976A AU 8697601 A AU8697601 A AU 8697601A AU 2001286976 A1 AU2001286976 A1 AU 2001286976A1
- Authority
- AU
- Australia
- Prior art keywords
- uses therefor
- autoinducer molecules
- novel
- novel autoinducer
- molecules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/045—Culture media therefor
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22971500P | 2000-08-31 | 2000-08-31 | |
US60229715 | 2000-08-31 | ||
PCT/US2001/027165 WO2002018342A2 (en) | 2000-08-31 | 2001-08-31 | Novel autoinducer molecules and uses therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001286976A1 true AU2001286976A1 (en) | 2002-03-13 |
Family
ID=22862409
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001286976A Abandoned AU2001286976A1 (en) | 2000-08-31 | 2001-08-31 | Novel autoinducer molecules and uses therefor |
Country Status (3)
Country | Link |
---|---|
US (2) | US20020177715A1 (en) |
AU (1) | AU2001286976A1 (en) |
WO (1) | WO2002018342A2 (en) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1450802A2 (en) * | 2001-10-30 | 2004-09-01 | The General Hospital Corporation | Methods for the prevention or treatment of bacterial and fungal infections |
KR20110124375A (en) | 2002-08-13 | 2011-11-16 | 햅토젠 리미티드 | Methods for the treatment of an infectious bacterial disease with an anti-lactone or lactone derived signal molecules antibody |
US7498292B2 (en) | 2002-08-15 | 2009-03-03 | The Research Foundation Of State University Of New York | Combinatorial libraries of autoinducer analogs, autoinducer agonists and antagonists, and methods of use thereof |
US20050032093A1 (en) * | 2003-04-17 | 2005-02-10 | Tony Romeo | Novel genes involved in the escherichia coli biofilm formation and uses thereof |
US20050074827A1 (en) * | 2003-07-18 | 2005-04-07 | Ute Muh | Methods for identifying modulators of quorum-sensing signaling in bacteria |
GB0326194D0 (en) * | 2003-11-10 | 2003-12-17 | Univ Kent Canterbury | Proteins involved in signal transduction |
US7122700B2 (en) | 2004-07-30 | 2006-10-17 | Xerox Corporation | Arylamine processes |
WO2006084056A2 (en) | 2005-02-04 | 2006-08-10 | Wisconsin Alumni Research Foundation | Compounds and methods for modulating communication and virulence in quorum sensing bacteria |
CN100387586C (en) * | 2005-03-18 | 2008-05-14 | 中国科学院理化技术研究所 | Synthesis method of chiral 2-amino-1- (6-fluoro-3, 4-dihydrobenzopyranyl) ethanol |
WO2007008769A2 (en) * | 2005-07-08 | 2007-01-18 | George Mason University | Use of pseudan and pseudan inclusion bodies |
EP1782826A1 (en) * | 2005-11-08 | 2007-05-09 | GBF Gesellschaft für Biotechnologische Forschung mbH | PQS and c-diGMP and its conjugates as adjuvants and their uses in pharmaceutical compositions |
US7910622B2 (en) * | 2007-03-19 | 2011-03-22 | Wisconsin Alumni Research Foundation | Modulation of bacterial quorum sensing with synthetic ligands |
WO2009036081A1 (en) * | 2007-09-10 | 2009-03-19 | University Of Kentucky Research Foundation | Systems and methods for diagnosis and monitoring of bacteria-related conditions |
WO2009063901A1 (en) * | 2007-11-13 | 2009-05-22 | The University Of Tokyo | Quorum sensing inhibitor |
US8624063B2 (en) | 2009-06-30 | 2014-01-07 | Wisconsin Alumni Research Foundation | Non-lactone carbocyclic and heterocyclic antagonists and agonists of bacterial quorum sensing |
CN102706821B (en) * | 2012-06-15 | 2014-11-12 | 广东工业大学 | Method for quickly identifying food-borne pathogen bacterial biofilm formation inhibitor |
GB201513614D0 (en) | 2015-07-31 | 2015-09-16 | Univ College Cork Nat Univ Ie | Compositions, compounds and methods and uses relating thereto |
EP3260445A1 (en) * | 2016-06-24 | 2017-12-27 | Universität Konstanz | Compounds for use as an anti-bacterial or anti-fungal agent and as a zinc sensor |
US10526278B2 (en) | 2017-10-19 | 2020-01-07 | Wisconsin Alumni Research Foundation | Inhibitors of quorum sensing receptor LasR |
EP3502095A1 (en) | 2017-12-22 | 2019-06-26 | Universität Konstanz | Compound for use against pathogenic neisseria and haemophilus species and moraxella catarrhalis |
US20220015363A1 (en) * | 2020-07-14 | 2022-01-20 | The Trustees Of Princeton University | Small molecule pathogen dispersal agent |
CN113201473B (en) | 2021-04-22 | 2022-06-07 | 广东省科学院微生物研究所(广东省微生物分析检测中心) | Application of citronellol in preparation of preparation for promoting pseudomonas aeruginosa virulence gene toxA expression |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5842869B2 (en) | 1981-11-30 | 1983-09-22 | 三菱瓦斯化学株式会社 | Homoserine lactone derivative |
US4650750A (en) * | 1982-02-01 | 1987-03-17 | Giese Roger W | Method of chemical analysis employing molecular release tag compounds |
US4709016A (en) * | 1982-02-01 | 1987-11-24 | Northeastern University | Molecular analytical release tags and their use in chemical analysis |
JPS5951267A (en) * | 1982-09-14 | 1984-03-24 | Nippon Redarii Kk | Quinoline-n-oxide derivative |
JPS6045568A (en) | 1983-08-23 | 1985-03-12 | Mitsubishi Gas Chem Co Inc | Production of homoserine lactone derivative |
JPS6165869A (en) * | 1984-09-07 | 1986-04-04 | Kyowa Hakko Kogyo Co Ltd | Quinoline-n-oxide derivative |
JPH04360884A (en) * | 1991-02-08 | 1992-12-14 | Hoechst Ag | Method for manufacturing homoserine lactone |
GB9108307D0 (en) | 1991-04-18 | 1991-06-05 | Univ Nottingham | Autoinducer |
US5320805A (en) * | 1991-05-15 | 1994-06-14 | Sterilex Corporation | Methods of using a cleaner, sanitizer, disinfectant, fungicide, sporicide, chemical sterilizer |
US5536750A (en) * | 1992-10-29 | 1996-07-16 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
US5686472A (en) * | 1992-10-29 | 1997-11-11 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
AU7077894A (en) * | 1993-07-02 | 1995-01-24 | University Of Nottingham, The | Immunosuppressant and antiallergic compounds, e.g. n-(3-oxohexanoyl) homoserine lactone |
US5591872A (en) * | 1993-08-09 | 1997-01-07 | The University Of Iowa Research Foundation | Autoinducer molecule |
JP3071990B2 (en) * | 1993-12-27 | 2000-07-31 | 花王株式会社 | External preparation for skin |
GB9407869D0 (en) * | 1994-04-20 | 1994-06-15 | Caduceus Ltd | Antimicrobial compounds |
AUPN191295A0 (en) | 1995-03-23 | 1995-04-27 | Unisearch Limited | Microbiocide or microbial regulator |
US5942619A (en) * | 1995-09-29 | 1999-08-24 | Pfizer Inc. | Quinolone compounds for the treatment of disorders caused by helicobacter pylori |
WO1997027851A1 (en) | 1996-02-01 | 1997-08-07 | The Johns-Hopkins University | L-homoserine and l-homoserine lactone as bacteriostatic agents for m. tuberculosis and m. bovis |
JP3592918B2 (en) * | 1997-05-14 | 2004-11-24 | 花王株式会社 | Cosmetics |
EP0994961B1 (en) | 1997-06-18 | 2006-10-18 | Montana State University - Bozeman | Homoserine lactones biofilm regulating compounds and their methods of use |
US6455031B1 (en) * | 1997-06-18 | 2002-09-24 | David G Davies | Methods and compositions for controlling biofilm development |
JP3669818B2 (en) | 1997-07-09 | 2005-07-13 | 電気化学工業株式会社 | Hexagonal boron nitride powder |
JPH1192307A (en) * | 1997-09-24 | 1999-04-06 | Marine Biotechnol Inst Co Ltd | Antifouling agent |
US6337347B1 (en) * | 1998-06-18 | 2002-01-08 | The Research & Development Institute, Inc. | Autoinducer compounds |
JP2000302682A (en) * | 1999-04-23 | 2000-10-31 | Yamanouchi Pharmaceut Co Ltd | Anti-helicobacter pylori agent |
EP1250450A2 (en) | 1999-09-03 | 2002-10-23 | University of Iowa Research Foundation Inc. | Quorum sensing signaling in bacteria |
-
2001
- 2001-08-31 WO PCT/US2001/027165 patent/WO2002018342A2/en active Application Filing
- 2001-08-31 AU AU2001286976A patent/AU2001286976A1/en not_active Abandoned
- 2001-08-31 US US09/945,325 patent/US20020177715A1/en not_active Abandoned
-
2004
- 2004-09-16 US US10/844,037 patent/US7442798B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US20050009869A1 (en) | 2005-01-13 |
WO2002018342A2 (en) | 2002-03-07 |
US20020177715A1 (en) | 2002-11-28 |
WO2002018342A3 (en) | 2002-05-10 |
US7442798B2 (en) | 2008-10-28 |
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