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AU2001284466A1 - Tetraphenylbacteriochlorin derivatives and compositions containing the same - Google Patents

Tetraphenylbacteriochlorin derivatives and compositions containing the same

Info

Publication number
AU2001284466A1
AU2001284466A1 AU2001284466A AU8446601A AU2001284466A1 AU 2001284466 A1 AU2001284466 A1 AU 2001284466A1 AU 2001284466 A AU2001284466 A AU 2001284466A AU 8446601 A AU8446601 A AU 8446601A AU 2001284466 A1 AU2001284466 A1 AU 2001284466A1
Authority
AU
Australia
Prior art keywords
same
compositions containing
tetraphenylbacteriochlorin
chem
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001284466A
Inventor
Toyoji Kakuchi
Yuji Mikata
Shigenobu Yano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
San Ei Gen FFI Inc
Original Assignee
Inc San Ei Gen F F I
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inc San Ei Gen F F I filed Critical Inc San Ei Gen F F I
Publication of AU2001284466A1 publication Critical patent/AU2001284466A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Provided is a tetraphenylbacteriochlorin derivative represented by the formula (I): <CHEM> Äwherein R<1>, R<2>, R<3> and R<4>, independently from each other, are a residue of a monosaccharide represented by the formulae: <CHEM> (wherein, R is a hydrogen or a protecting group)Ü, or its salt. The tetraphenylbacteriochlorin derivative or its salt has a large molar extinction coefficient at long wavelengths which are expected to have a high tissue-penetrating property, and exhibits high selectivity to tumor cells and hydrophilicity. <IMAGE>
AU2001284466A 2000-09-08 2001-09-06 Tetraphenylbacteriochlorin derivatives and compositions containing the same Abandoned AU2001284466A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000273649 2000-09-08
JP2000-273649 2000-09-08
PCT/JP2001/007758 WO2002020536A1 (en) 2000-09-08 2001-09-06 Tetraphenylbacteriochlorin derivatives and compositions containing the same

Publications (1)

Publication Number Publication Date
AU2001284466A1 true AU2001284466A1 (en) 2002-03-22

Family

ID=18759554

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001284466A Abandoned AU2001284466A1 (en) 2000-09-08 2001-09-06 Tetraphenylbacteriochlorin derivatives and compositions containing the same

Country Status (7)

Country Link
US (2) US6958389B2 (en)
EP (1) EP1316558B9 (en)
JP (1) JP4944348B2 (en)
AT (1) ATE302209T1 (en)
AU (1) AU2001284466A1 (en)
DE (1) DE60112769T2 (en)
WO (1) WO2002020536A1 (en)

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US8287839B2 (en) * 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US20090318370A1 (en) * 2007-02-19 2009-12-24 Rei Medical Co., Ltd. Novel glycoconjugated chlorin derivatives and method of producing the same
US8444953B2 (en) * 2007-03-22 2013-05-21 Brookhaven Science Associates, Llc Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof
US20080279781A1 (en) * 2007-05-10 2008-11-13 Brookhaven Science Associates, Llc Glycosylated Carboranylporphyrins and Uses Thereof
JP6041360B2 (en) * 2011-07-22 2016-12-07 バイオリテック ウンターネーメンスベタイリグンクス ツヴァイ アクツィエンゲゼルシャフト Sugar-substituted dihydroxy-chlorins and β-functionalized chlorins for antibacterial photodynamic therapy
CN102558187B (en) * 2011-12-29 2014-02-26 东华大学 Tetrahydroporphin compound and preparation method and application thereof
CN108715591B (en) * 2018-06-01 2021-04-13 华东理工大学 Near infrared absorbing porphyrin compounds as photosensitizers and uses thereof
CN109481696B (en) * 2018-12-22 2020-10-02 吉林大学 Medicine for cancer photodynamic therapy and chemotherapy and preparation method thereof

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Also Published As

Publication number Publication date
DE60112769D1 (en) 2005-09-22
DE60112769T2 (en) 2006-06-08
EP1316558B9 (en) 2005-12-07
EP1316558B1 (en) 2005-08-17
EP1316558A4 (en) 2004-04-07
US20030171305A1 (en) 2003-09-11
ATE302209T1 (en) 2005-09-15
US7157432B2 (en) 2007-01-02
JPWO2002020536A1 (en) 2004-01-15
US6958389B2 (en) 2005-10-25
US20060003946A1 (en) 2006-01-05
WO2002020536A1 (en) 2002-03-14
JP4944348B2 (en) 2012-05-30
EP1316558A1 (en) 2003-06-04

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