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AU2001268545A1 - Libraries displaying human antibody fragments with hybrid complementarity determining regions - Google Patents

Libraries displaying human antibody fragments with hybrid complementarity determining regions

Info

Publication number
AU2001268545A1
AU2001268545A1 AU2001268545A AU6854501A AU2001268545A1 AU 2001268545 A1 AU2001268545 A1 AU 2001268545A1 AU 2001268545 A AU2001268545 A AU 2001268545A AU 6854501 A AU6854501 A AU 6854501A AU 2001268545 A1 AU2001268545 A1 AU 2001268545A1
Authority
AU
Australia
Prior art keywords
hybrid
antibody fragments
human antibody
complementarity determining
determining regions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001268545A
Inventor
William L Fodor
Russell Rother
Stephen P Squinto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alexion Pharmaceuticals Inc
Original Assignee
Alexion Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexion Pharmaceuticals Inc filed Critical Alexion Pharmaceuticals Inc
Publication of AU2001268545A1 publication Critical patent/AU2001268545A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
AU2001268545A 2000-06-21 2001-06-18 Libraries displaying human antibody fragments with hybrid complementarity determining regions Abandoned AU2001268545A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21319600P 2000-06-21 2000-06-21
US60213196 2000-06-21
PCT/US2001/019502 WO2002000005A1 (en) 2000-06-21 2001-06-18 Libraries displaying human antibody fragments with hybrid complementarity determining regions

Publications (1)

Publication Number Publication Date
AU2001268545A1 true AU2001268545A1 (en) 2002-01-08

Family

ID=22794104

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001268545A Abandoned AU2001268545A1 (en) 2000-06-21 2001-06-18 Libraries displaying human antibody fragments with hybrid complementarity determining regions

Country Status (2)

Country Link
AU (1) AU2001268545A1 (en)
WO (1) WO2002000005A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4782700B2 (en) * 2004-01-20 2011-09-28 カロバイオス ファーマシューティカルズ インコーポレイティッド Transfer of antibody specificity using minimally required binding determinants
ES2744149T3 (en) 2004-11-16 2020-02-21 Humanigen Inc Exchange of cassettes of the immunoglobulin variable region
JO2787B1 (en) 2005-04-27 2014-03-15 امجين إنك, Substituted Amid derivatives & methods of use
WO2015133882A1 (en) * 2014-03-07 2015-09-11 사회복지법인 삼성생명공익재단 Scfv antibody library, method for preparing same, and scfv antibody screening method using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565332A (en) * 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
JP2001523958A (en) * 1997-03-21 2001-11-27 ブライハム アンド ウィミンズ ホスピタル，インコーポレイテッド CTLA-4 binding peptides for immunotherapy
US6160099A (en) * 1998-11-24 2000-12-12 Jonak; Zdenka Ludmila Anti-human αv β3 and αv β5 antibodies

Also Published As

Publication number Publication date
WO2002000005A1 (en) 2002-01-03
WO2002000005A8 (en) 2002-03-07

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