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AU2001267475A1 - Combinations of Enzyme Inhibitor-Containing Preparations and the use thereof - Google Patents

Combinations of Enzyme Inhibitor-Containing Preparations and the use thereof

Info

Publication number
AU2001267475A1
AU2001267475A1 AU2001267475A AU2001267475A AU2001267475A1 AU 2001267475 A1 AU2001267475 A1 AU 2001267475A1 AU 2001267475 A AU2001267475 A AU 2001267475A AU 2001267475 A AU2001267475 A AU 2001267475A AU 2001267475 A1 AU2001267475 A1 AU 2001267475A1
Authority
AU
Australia
Prior art keywords
combinations
enzyme inhibitor
containing preparations
preparations
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2001267475A
Other versions
AU2001267475B2 (en
Inventor
Siegfried Ansorge
Marco Arndt
Stefan Brocke
Frank Buhling
Uwe Lendeckel
Klaus Neubert
Dirk Reinhold
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMTM GmbH
Original Assignee
IMTM GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10025464A external-priority patent/DE10025464A1/en
Application filed by IMTM GmbH filed Critical IMTM GmbH
Publication of AU2001267475A1 publication Critical patent/AU2001267475A1/en
Application granted granted Critical
Publication of AU2001267475B2 publication Critical patent/AU2001267475B2/en
Assigned to IMTM GMBH reassignment IMTM GMBH Request to Amend Deed and Register Assignors: INSTITUT FUR MEDIZINTECHNOLOGIE MAGDEBURG GMBH IMTM
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2001267475A 2000-05-23 2001-05-22 Combinations of enzyme inhibitor-containing preparations and the use thereof Ceased AU2001267475B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10025464.0 2000-05-23
DE10025464A DE10025464A1 (en) 2000-05-23 2000-05-23 Combined use of enzyme inhibitors for the therapy of autoimmune diseases, in transplants and tumor diseases, as well as combinations of pharmaceutical preparations comprising enzyme inhibitors
PCT/EP2001/005887 WO2001089569A1 (en) 2000-05-23 2001-05-22 Combinations of enzyme inhibitor-containing preparations and the use thereof

Publications (2)

Publication Number Publication Date
AU2001267475A1 true AU2001267475A1 (en) 2002-02-21
AU2001267475B2 AU2001267475B2 (en) 2004-11-04

Family

ID=7643220

Family Applications (2)

Application Number Title Priority Date Filing Date
AU6747501A Pending AU6747501A (en) 2000-05-23 2001-05-22 Combinations of enzyme inhibitor-containing preparations and the use thereof
AU2001267475A Ceased AU2001267475B2 (en) 2000-05-23 2001-05-22 Combinations of enzyme inhibitor-containing preparations and the use thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU6747501A Pending AU6747501A (en) 2000-05-23 2001-05-22 Combinations of enzyme inhibitor-containing preparations and the use thereof

Country Status (11)

Country Link
US (1) US7485626B2 (en)
EP (1) EP1289559B8 (en)
JP (1) JP4965787B2 (en)
CN (1) CN1430519A (en)
AT (1) ATE300313T1 (en)
AU (2) AU6747501A (en)
CA (1) CA2410305C (en)
DE (2) DE10025464A1 (en)
DK (1) DK1289559T3 (en)
ES (1) ES2243516T3 (en)
WO (1) WO2001089569A1 (en)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19828113A1 (en) 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs of Dipeptidyl Peptidase IV Inhibitors
DE19940130A1 (en) 1999-08-24 2001-03-01 Probiodrug Ges Fuer Arzneim New effectors of Dipeptidyl Peptidase IV for topical use
DE10025464A1 (en) * 2000-05-23 2001-12-06 Inst Medizintechnologie Magdeb Combined use of enzyme inhibitors for the therapy of autoimmune diseases, in transplants and tumor diseases, as well as combinations of pharmaceutical preparations comprising enzyme inhibitors
DE10155093A1 (en) * 2001-11-09 2003-06-12 Inst Medizintechnologie Magdeb Inhibiting DNA synthesis in T-lymphocytes, keratinocytes and TH2 cytokine production, comprises combined administration of dipeptidyl peptidase and alanyl-aminopeptidase inhibitors
DE10100053A1 (en) * 2001-01-02 2002-08-22 Keyneurotek Ag I G Use of enzyme inhibitors of dipeptidyl peptidase IV and aminopeptidase N and pharmaceutical preparations therefrom for the prevention and / or therapy of ischemia-related acute and chronic neurodegenerative processes and diseases
WO2002053170A2 (en) 2001-01-02 2002-07-11 Institut Für Medizintechnologie Magdeburg Gmbh (Imtm) Combined use of enzyme inhibitors and pharmaceutical preparations thereof for the treatment and prophylaxis of arteriosclerosis, for the treatment and prevention of allergic reactions of type i according to the gell and coombs classification, and for the treatment and prevention of dermatological diseases associated with fo
US6890905B2 (en) 2001-04-02 2005-05-10 Prosidion Limited Methods for improving islet signaling in diabetes mellitus and for its prevention
US7368421B2 (en) 2001-06-27 2008-05-06 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
WO2003002530A2 (en) * 2001-06-27 2003-01-09 Smithkline Beecham Corporation Pyrrolidines as dipeptidyl peptidase inhibitors
DE10150203A1 (en) 2001-10-12 2003-04-17 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitor in treatment of cancer
US20030130199A1 (en) 2001-06-27 2003-07-10 Von Hoersten Stephan Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
CN1321682C (en) * 2001-06-27 2007-06-20 前体生物药物股份有限公司 New dipeptidyl peptidase iv inhibitors and their uses as anti-cancer agents
US6844316B2 (en) 2001-09-06 2005-01-18 Probiodrug Ag Inhibitors of dipeptidyl peptidase I
WO2003045228A2 (en) * 2001-11-26 2003-06-05 Trustees Of Tufts College Methods for treating autoimmune disorders, and reagents related thereto
EA007434B1 (en) 2002-02-28 2006-10-27 Прозидион Лимитед Glutaminyl based dpiv inhibitors
DE10211555A1 (en) * 2002-03-15 2003-10-02 Imtm Inst Fuer Medizintechnolo Use of the inhibitors of enzymes with activities of the aminopeptidase N and / or the dipeptidyl peptidase IV and pharmaceutical preparations thereof for the therapy and prevention of dermatological diseases with sebocytic hyperproliferation and changed differentiation states
DE10230381A1 (en) 2002-07-05 2004-01-22 Institut für Medizintechnologie Magdeburg GmbH, IMTM Use of inhibitors of alanyl aminopeptidases and pharmaceutical compositions comprising them
JP2006507352A (en) * 2002-07-09 2006-03-02 ポイント セラピューティクス， インコーポレイテッド Methods and compositions for boroproline compounds of isoleucine
WO2004104575A2 (en) * 2003-05-23 2004-12-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with x-prolyl aminopeptidase 2 (xpnpep2)
DE10330842A1 (en) 2003-07-08 2005-02-10 Institut für Medizintechnologie Magdeburg GmbH, IMTM Use of the inhibitors of enzymes with activities of aminopeptidase N and / or dipeptidyl peptidase IV and pharmaceutical preparations thereof for the therapy and prevention of dermatological diseases with hyperproliferation and altered differentiation states of fibroblasts
US7169926B1 (en) 2003-08-13 2007-01-30 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7678909B1 (en) 2003-08-13 2010-03-16 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
DE10348022A1 (en) * 2003-10-15 2005-05-25 Imtm Gmbh New dipeptidyl peptidase IV inhibitors for the functional influence of different cells and for the treatment of immunological, inflammatory, neuronal and other diseases
DE10348044A1 (en) 2003-10-15 2005-05-19 Imtm Gmbh Dual alanyl aminopeptidase and dipeptidyl peptidase IV inhibitors for the functional influence of different cells and for the treatment of immunological, inflammatory, neuronal and other diseases
DE10348023A1 (en) * 2003-10-15 2005-05-19 Imtm Gmbh New alanyl aminopeptidase inhibitors for the functional manipulation of different cells and for the treatment of immunological, inflammatory, neuronal and other diseases
GB0324236D0 (en) * 2003-10-16 2003-11-19 Astrazeneca Ab Chemical compounds
US7732446B1 (en) 2004-03-11 2010-06-08 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
WO2005118555A1 (en) * 2004-06-04 2005-12-15 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
WO2006019965A2 (en) 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
EA200702208A1 (en) * 2005-04-22 2008-04-28 Алантос Фармасьютиклз Холдинг, Инк. DIPEPTIDYLPEPTIDASE-IV INHIBITORS
EA015169B1 (en) 2005-09-14 2011-06-30 Такеда Фармасьютикал Компани Лимитед Use of dipeptidyl peptidase inhibitors
WO2007035629A2 (en) 2005-09-16 2007-03-29 Takeda Pharmaceutical Company Limited Process for the preparation of pyrimidinedione derivatives
DE102005054700B4 (en) 2005-11-16 2009-01-08 Imtm Gmbh New dual peptidase inhibitors as prodrugs for the treatment of inflammatory and other diseases
WO2007112347A1 (en) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
WO2008144748A1 (en) * 2007-05-21 2008-11-27 The Uab Research Foundation Prolyl endopeptidase inhibitors for reducing or preventing neutrophilic inflammation
DE102007039429A1 (en) * 2007-08-21 2009-02-26 Imtm Gmbh Method for activating regulatory T cells
EP2292589A1 (en) 2009-09-02 2011-03-09 IMTM GmbH Novel multifunctional peptidase inhibitors, especially for medical use
EP2366394A1 (en) 2010-03-17 2011-09-21 IMTM GmbH Characterization and validation of inhibitors and ligands of dipeptidyl aminopeptidase IV (DP IV)
EP2418196A1 (en) * 2010-07-29 2012-02-15 IMTM GmbH Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors
CN105399701A (en) * 2013-01-06 2016-03-16 天津市汉康医药生物技术有限公司 Thiazolidine derivatives, as well as preparation method and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998044923A1 (en) * 1997-04-10 1998-10-15 Sloan-Kettering Institute For Cancer Research Anti-neoplastic effects of actinonin
JP2002506075A (en) * 1998-03-09 2002-02-26 フォンダテッヒ・ベネルクス・ナムローゼ・フェンノートシャップ Serine peptidase modulator
DE10025464A1 (en) * 2000-05-23 2001-12-06 Inst Medizintechnologie Magdeb Combined use of enzyme inhibitors for the therapy of autoimmune diseases, in transplants and tumor diseases, as well as combinations of pharmaceutical preparations comprising enzyme inhibitors
DE10100053A1 (en) * 2001-01-02 2002-08-22 Keyneurotek Ag I G Use of enzyme inhibitors of dipeptidyl peptidase IV and aminopeptidase N and pharmaceutical preparations therefrom for the prevention and / or therapy of ischemia-related acute and chronic neurodegenerative processes and diseases
WO2002053170A2 (en) * 2001-01-02 2002-07-11 Institut Für Medizintechnologie Magdeburg Gmbh (Imtm) Combined use of enzyme inhibitors and pharmaceutical preparations thereof for the treatment and prophylaxis of arteriosclerosis, for the treatment and prevention of allergic reactions of type i according to the gell and coombs classification, and for the treatment and prevention of dermatological diseases associated with fo

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