AU2001264595A1 - Sulfonamide and carbamide derivatives of 6(5h)phenanthridinones and their uses - Google Patents
Sulfonamide and carbamide derivatives of 6(5h)phenanthridinones and their usesInfo
- Publication number
- AU2001264595A1 AU2001264595A1 AU2001264595A AU6459501A AU2001264595A1 AU 2001264595 A1 AU2001264595 A1 AU 2001264595A1 AU 2001264595 A AU2001264595 A AU 2001264595A AU 6459501 A AU6459501 A AU 6459501A AU 2001264595 A1 AU2001264595 A1 AU 2001264595A1
- Authority
- AU
- Australia
- Prior art keywords
- phenanthridinones
- sulfonamide
- carbamide derivatives
- carbamide
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C07D221/12—Phenanthridines
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20525900P | 2000-05-19 | 2000-05-19 | |
US60205259 | 2000-05-19 | ||
PCT/US2001/015571 WO2001090077A1 (en) | 2000-05-19 | 2001-05-15 | Sulfonamide and carbamide derivatives of 6(5h)phenanthridinones and their uses |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001264595A1 true AU2001264595A1 (en) | 2001-12-03 |
Family
ID=22761477
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001264595A Abandoned AU2001264595A1 (en) | 2000-05-19 | 2001-05-15 | Sulfonamide and carbamide derivatives of 6(5h)phenanthridinones and their uses |
Country Status (3)
Country | Link |
---|---|
US (1) | US6723733B2 (en) |
AU (1) | AU2001264595A1 (en) |
WO (1) | WO2001090077A1 (en) |
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US6476048B1 (en) | 1999-12-07 | 2002-11-05 | Inotek Pharamaceuticals Corporation | Substituted phenanthridinones and methods of use thereof |
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US7151102B2 (en) | 2000-10-30 | 2006-12-19 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
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CA2482806A1 (en) | 2002-04-30 | 2003-11-13 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
CA2517260A1 (en) * | 2003-02-28 | 2005-02-03 | Inotek Pharmaceuticals Corporation | Tetracyclic benzamide derivatives and methods of use thereof |
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US7449464B2 (en) | 2003-03-12 | 2008-11-11 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
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GB0412553D0 (en) * | 2004-06-04 | 2004-07-07 | Univ Aberdeen | Therapeutic agents for the treatment of bone conditions |
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CN101674832A (en) * | 2007-02-28 | 2010-03-17 | 伊诺泰克制药公司 | Indenoisoquinolinone analogs and methods of use thereof |
GB0705400D0 (en) | 2007-03-21 | 2007-05-02 | Univ Aberdeen | Therapeutic compounds andm their use |
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WO2010081778A1 (en) * | 2009-01-17 | 2010-07-22 | Universität Zürich | Blockers of parp for the prevention and treatment of helicobacter pylori induced gastric cancer |
CN102574791A (en) | 2009-08-05 | 2012-07-11 | 无限药品股份有限公司 | Enzymatic transamination of cyclopamine analogs |
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TWI574962B (en) * | 2012-11-14 | 2017-03-21 | 加拓科學公司 | Heteroaromatic compounds as pi3 kinase modulators and methods of use |
JP6360500B2 (en) * | 2013-02-06 | 2018-07-18 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | Substituted carboxylic acid derivatives as aggrecanase inhibitors for the treatment of osteoarthritis |
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AU2015367528B2 (en) | 2014-12-17 | 2020-05-14 | Pimco 2664 Limited | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and their therapeutic use |
MX2017015681A (en) | 2015-06-04 | 2018-09-11 | Pellepharm Inc | Topical formulations for delivery of hedgehog inhibitor compounds and use thereof. |
CN106316953B (en) * | 2015-06-15 | 2019-02-01 | 浙江工业大学 | A kind of synthetic method of 6- cyano phenanthridines class compound |
US10563197B2 (en) | 2015-07-23 | 2020-02-18 | Institut Curie | Use of a combination of Dbait molecule and PARP inhibitors to treat cancer |
CN105131974B (en) * | 2015-07-28 | 2017-04-12 | 江苏和成新材料有限公司 | Phenanthridone-structure heterocyclic polymerizable liquid crystal compound and preparation method thereof |
GB201519573D0 (en) | 2015-11-05 | 2015-12-23 | King S College London | Combination |
WO2018022851A1 (en) | 2016-07-28 | 2018-02-01 | Mitobridge, Inc. | Methods of treating acute kidney injury |
CA3041843A1 (en) | 2016-11-02 | 2018-05-11 | Immunogen, Inc. | Combination treatment with antibody-drug conjugates and parp inhibitors |
WO2018162439A1 (en) | 2017-03-08 | 2018-09-13 | Onxeo | New predictive biomarker for the sensitivity to a treatment of cancer with a dbait molecule |
US20200129476A1 (en) | 2017-04-28 | 2020-04-30 | Akribes Biomedical Gmbh | PARP Inhibitor in Combination with a Glucocorticoid and/or Ascorbic Acid and/or a Protein Growth Factor for the Treatment of Impaired Wound Healing |
US11504379B2 (en) * | 2017-08-07 | 2022-11-22 | Hiroshima University | Amide compound, and Pin1 inhibitor, therapeutic agent for inflammatory diseases and therapeutic agent for cancer that use the same |
JP7534218B2 (en) | 2018-03-13 | 2024-08-14 | ヴァレリオ・セラピューティクス | DBAIT molecules combating acquired resistance in cancer treatment |
CN110256346A (en) * | 2019-07-03 | 2019-09-20 | 浙江省医学科学院 | Phenanthridines ketone compounds and preparation method and application with BRD4 albumen inhibiting effect |
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-
2001
- 2001-05-15 AU AU2001264595A patent/AU2001264595A1/en not_active Abandoned
- 2001-05-15 WO PCT/US2001/015571 patent/WO2001090077A1/en active Application Filing
- 2001-05-15 US US09/854,455 patent/US6723733B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6723733B2 (en) | 2004-04-20 |
WO2001090077A1 (en) | 2001-11-29 |
US20020006927A1 (en) | 2002-01-17 |
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