[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

AU2001262150A1 - 2-(nitrogen-heterocyclic)pyrimidone derivatives - Google Patents

2-(nitrogen-heterocyclic)pyrimidone derivatives

Info

Publication number
AU2001262150A1
AU2001262150A1 AU2001262150A AU6215001A AU2001262150A1 AU 2001262150 A1 AU2001262150 A1 AU 2001262150A1 AU 2001262150 A AU2001262150 A AU 2001262150A AU 6215001 A AU6215001 A AU 6215001A AU 2001262150 A1 AU2001262150 A1 AU 2001262150A1
Authority
AU
Australia
Prior art keywords
heterocyclic
nitrogen
pyrimidone derivatives
pyrimidone
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001262150A
Inventor
Antonio Almario Garcia
Ryoichi Ando
Jonathan Reid Frost
Adrien Tak Li
Aya Shoda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Mitsubishi Pharma Corp
Original Assignee
Sanofi Synthelabo SA
Mitsubishi Tokyo Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP00400801A external-priority patent/EP1136483A1/en
Priority claimed from EP00400802A external-priority patent/EP1136489A1/en
Priority claimed from EP00400803A external-priority patent/EP1136493A1/en
Application filed by Sanofi Synthelabo SA, Mitsubishi Tokyo Pharmaceuticals Inc filed Critical Sanofi Synthelabo SA
Publication of AU2001262150A1 publication Critical patent/AU2001262150A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001262150A 2000-03-23 2001-03-22 2-(nitrogen-heterocyclic)pyrimidone derivatives Abandoned AU2001262150A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP00400802 2000-03-23
EP00400801A EP1136483A1 (en) 2000-03-23 2000-03-23 2-[Piperazinyl]pyrimidone derivatives
EP00400802A EP1136489A1 (en) 2000-03-23 2000-03-23 2-[Piperidin-1-yl]pyrimidone derivatives
EP00400803A EP1136493A1 (en) 2000-03-23 2000-03-23 2-(Thienopyridinyl)pyrimidone, 2-(furopyridinyl)pyrimidone 2-(isoquinolinyl)pyrimidone, 2-(pyridoindolyl)pyrimidone and 2-(benzofuropyridinyl)pyrimidone derivatives
EP00400803 2000-03-23
EP00400801 2000-03-23
PCT/EP2001/003639 WO2001070728A1 (en) 2000-03-23 2001-03-22 2-[nitrogen-heterocyclic]pyrimidone derivatives

Publications (1)

Publication Number Publication Date
AU2001262150A1 true AU2001262150A1 (en) 2001-10-03

Family

ID=27223599

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001262150A Abandoned AU2001262150A1 (en) 2000-03-23 2001-03-22 2-(nitrogen-heterocyclic)pyrimidone derivatives

Country Status (2)

Country Link
AU (1) AU2001262150A1 (en)
WO (1) WO2001070728A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR023052A1 (en) 1998-09-25 2002-09-04 Mitsuharu Yoshimura Milton DERIVATIVES OF PIRIMIDONA
KR100754596B1 (en) 2001-09-21 2007-09-05 미쯔비시 웰 파마 가부시키가이샤 3-substituted-4-pyrimidone derivatives
AU2002337499B2 (en) 2001-09-21 2007-08-23 Mitsubishi Pharma Corporation 3-substituted-4-pyrimidone derivatives
EA009027B1 (en) * 2002-12-16 2007-10-26 Мицубиси Фарма Корпорейшн 3-substituted-4-pirimidone derivatives
EP1454910A1 (en) * 2003-03-07 2004-09-08 Sanofi-Synthelabo Substituted pyrimidinyl-2-(diaza-bicyclo-alkyl)-pyrimidone derivatives
EP1454908B1 (en) * 2003-03-07 2008-02-27 Sanofi-Aventis Substituted pyridinyl-2-(diaza-bicyclo-alkyl)-pyrimidinone derivatives
ES2332132T3 (en) * 2003-03-07 2010-01-27 Sanofi-Aventis DERIVATIVES OF 2- (DIAZA-BICICLO-ALQUIL) -PIRIMIDONA SUBSTITUTES.
WO2004080977A1 (en) * 2003-03-12 2004-09-23 Vertex Pharmaceuticals Incorporated 4-substituted-5-cyano-1h-pyrimidin-6-(thi)ones as gsk-3 inhibitors
TWI357408B (en) * 2003-03-26 2012-02-01 Mitsubishi Tanabe Pharma Corp 3-substituted-4-pyrimidone derivatives
JP2007534624A (en) * 2003-07-16 2007-11-29 ニューロジェン・コーポレーション Biaryl piperazinyl-pyridine analogues
GEP20094640B (en) 2004-07-15 2009-03-10 Bristol Myers Squibb Co Aryl-and heteroaryl-substituted tetrahydro isoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
MY145822A (en) 2004-08-13 2012-04-30 Neurogen Corp Substituted biaryl piperazinyl-pyridine analogues
AR050865A1 (en) * 2004-09-09 2006-11-29 Sanofi Aventis DERIVATIVES OF 2- MORFOLINO-4-PIRIMIDONA
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
US7678363B2 (en) 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
TW200813015A (en) * 2006-03-15 2008-03-16 Mitsubishi Pharma Corp 2-(cyclic amino)-pyrimidone derivatives
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
AR064660A1 (en) 2006-12-26 2009-04-15 Mitsubishi Tanabe Pharma Corp DERIVATIVES OF PIRIMIDINONA 6-HETEROCICLICA 2-REPLACED, MEDICINES THAT CONTAIN THEM AND USES TO PREVENT AND / OR TREAT NEURODEGENERATIVE DISEASES BETWEEN OTHER
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
EP2138498A1 (en) * 2008-06-26 2009-12-30 sanofi-aventis Substituted tricyclic derivatives against neurodegenerative diseases
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
WO2010132487A1 (en) 2009-05-12 2010-11-18 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
MX2011011901A (en) 2009-05-12 2012-01-20 Albany Molecular Res Inc Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof.
US8802696B2 (en) 2009-05-12 2014-08-12 Albany Molecular Research, Inc. 7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoqu inoli and use thereof
MX2017005719A (en) * 2014-11-03 2017-12-07 Iomet Pharma Ltd Pharmaceutical compound.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998024782A2 (en) * 1996-12-05 1998-06-11 Amgen Inc. Substituted pyrimidine compounds and their use
AR023052A1 (en) * 1998-09-25 2002-09-04 Mitsuharu Yoshimura Milton DERIVATIVES OF PIRIMIDONA

Also Published As

Publication number Publication date
WO2001070728A1 (en) 2001-09-27

Similar Documents

Publication Publication Date Title
AU2001262150A1 (en) 2-(nitrogen-heterocyclic)pyrimidone derivatives
AU2002221047A1 (en) Quinazolinone derivatives
AU2001280099A1 (en) 4-acylaminopyrazole derivatives
AU2001230584A1 (en) 1h-imidazopyridine derivatives
HK1054940A1 (en) Pyrimidine derivatives
AU1041802A (en) Tetrahydro-heterocycloazepinyl pyrimidine derivatives
AU2001230537A1 (en) Pyridoxazine derivatives
AU2001244634A1 (en) Diazepane derivatives or salts thereof
AU2002349777A1 (en) Novel benzophenone derivatives or salts thereof
AU2002212436A1 (en) Quinazoline derivatives
AU2001281802A1 (en) 6-phenylpyrrolopyrimidinedione derivatives
AU4556700A (en) Pyrimidine compounds
AU2001278790A1 (en) 1h-imidazopyridine derivatives
AU2002216314A1 (en) Heterocyclic angiogenesis inhibitors
AU2001292137A1 (en) Quinazoline derivatives
AU2001243615A1 (en) Secure tracking of articles
AU2002234010A1 (en) Benzamidine derivatives
AU2002213978A1 (en) Substituted C-cyclohexylmethylamine derivatives
AU2002362806A1 (en) Pyrimidine derivatives
AU2002212301A1 (en) Diazacycloalkanedione derivatives
AU2002232468A1 (en) Pharmaceutical heterocyclic compounds
AU2001267852A1 (en) Novel pyrazinone derivatives
AU2001242523A1 (en) Aminophenyl pyrimidone derivatives
AU2002212959A1 (en) Cycloalkylfluorosulfonamide derivatives
AU2001289937A1 (en) Substituted 1-aminobutan-3-ol derivatives