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AU2001256965A1 - Bactericidal antimicrobial methods and compositions for use in treating gram positive infections comprising an antibiotic potentiator having acyl hydrazide oxy amide or 8-hydroxy quinoline structure - Google Patents

Bactericidal antimicrobial methods and compositions for use in treating gram positive infections comprising an antibiotic potentiator having acyl hydrazide oxy amide or 8-hydroxy quinoline structure

Info

Publication number
AU2001256965A1
AU2001256965A1 AU2001256965A AU5696501A AU2001256965A1 AU 2001256965 A1 AU2001256965 A1 AU 2001256965A1 AU 2001256965 A AU2001256965 A AU 2001256965A AU 5696501 A AU5696501 A AU 5696501A AU 2001256965 A1 AU2001256965 A1 AU 2001256965A1
Authority
AU
Australia
Prior art keywords
compositions
gram positive
hydroxy quinoline
acyl hydrazide
quinoline structure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001256965A
Inventor
David Crich
Mohamad-Rami Jaber
Michael E. Johnson
Ekaterina A. Klyachko
Penelope N. Markham
Debbie C. Mulhearn
Alexander A. Neyfakh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Influx Inc
Original Assignee
Influx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Influx Inc filed Critical Influx Inc
Publication of AU2001256965A1 publication Critical patent/AU2001256965A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001256965A 2000-03-23 2001-03-23 Bactericidal antimicrobial methods and compositions for use in treating gram positive infections comprising an antibiotic potentiator having acyl hydrazide oxy amide or 8-hydroxy quinoline structure Abandoned AU2001256965A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19187900P 2000-03-23 2000-03-23
US60/191,879 2000-03-23
PCT/US2001/009578 WO2001070213A2 (en) 2000-03-23 2001-03-23 Bactericidal antimicrobial methods and compositions for use in treating gram positive infections comprising an antibiotic potentiator having acyl hydrazide oxy amide or 8-hydroxy quinoline structure

Publications (1)

Publication Number Publication Date
AU2001256965A1 true AU2001256965A1 (en) 2001-10-03

Family

ID=22707269

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001256965A Abandoned AU2001256965A1 (en) 2000-03-23 2001-03-23 Bactericidal antimicrobial methods and compositions for use in treating gram positive infections comprising an antibiotic potentiator having acyl hydrazide oxy amide or 8-hydroxy quinoline structure

Country Status (5)

Country Link
US (2) US20030225126A1 (en)
EP (1) EP1296688A2 (en)
JP (1) JP2003527417A (en)
AU (1) AU2001256965A1 (en)
WO (1) WO2001070213A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040110963A1 (en) * 2001-01-22 2004-06-10 Kaspar Burri Novel hydrazones
AUPS120902A0 (en) * 2002-03-19 2002-04-18 Unisearch Limited Iron chelators as anti-proliferative agents against tumour cells
AU2003225085A1 (en) * 2002-04-19 2003-11-03 California Institute Of Technology Unnatural amino acid containing display libraries
AU2003240545A1 (en) 2002-06-06 2003-12-22 Therapeutics Corporation Genome Use of ramoplanin to treat diseases associated with the use of antibiotics
DE10346913A1 (en) 2003-10-09 2005-05-04 Merck Patent Gmbh acylhydrazone
DE102004030987A1 (en) * 2004-06-26 2006-01-12 Merck Patent Gmbh Ortho-substituted (3-hydroxyphenyl) -acetic acid benzylidene hydrazides
US7604978B2 (en) * 2004-07-14 2009-10-20 Sequoia Sciences, Inc. Inhibition of biofilm formation
US20060014285A1 (en) * 2004-07-14 2006-01-19 Eldridge Gary R Methods and compositions for inhibiting biofilms
WO2006031943A1 (en) 2004-09-14 2006-03-23 Eldridge Gary R Compounds, compositions and methods for controlling biofilms and bacterial infections
US20060228384A1 (en) * 2005-04-06 2006-10-12 Sequoia Sciences, Inc. Control of biofilm with a biofilm inhibitor
US7600429B2 (en) * 2006-04-20 2009-10-13 Intel Corporation Vibration spectrum sensor array having differing sensors
WO2008014266A2 (en) * 2006-07-24 2008-01-31 University Of Maryland, Baltimore Heme oxygenase inhibitors and methods of therapeutic use
US7786139B2 (en) * 2006-11-21 2010-08-31 Omeros Corporation PDE10 inhibitors and related compositions and methods
EP1994930A1 (en) * 2007-05-22 2008-11-26 Novartis AG Triazol compounds for treating biofilm formation
CN101802610A (en) * 2007-09-20 2010-08-11 陶氏环球技术公司 A high throughput test method for evaluation of biocides against anaerobic microorganisms
WO2010151784A2 (en) * 2009-06-26 2010-12-29 The General Hospital Corporation Antimicrobial compounds
CA2808290A1 (en) * 2010-08-20 2012-02-23 Dow Agrosciences Llc Synergistic algicidal compositions including hydrazone derivatives and copper
WO2012027548A1 (en) * 2010-08-25 2012-03-01 The Feinstein Institute For Medical Research Compounds and methods for prevention and treatment of alzheimer's and other diseases
WO2012106364A1 (en) 2011-01-31 2012-08-09 The Government Of The United States, As Represented By The Secretary Of The Army Methods and compositions for treating bacterial infections with iron chelators
US8324264B1 (en) 2011-07-22 2012-12-04 Sequoia Sciences, Inc. Inhibitors of bacterial biofilms and related methods
CA3036765A1 (en) 2016-09-26 2018-06-21 Qingdao Primedicine Pharmaceutical Co., Ltd. N-methyl-d-aspartate receptor allosteric modulators and methods for their use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB811757A (en) * 1955-11-09 1959-04-08 Upjohn Co Production of an antibiotic designated antibiotic 101a fermentation
US4024256A (en) * 1974-02-11 1977-05-17 Griffith Donald P Method and composition for treating urinary tract infections
FR2580281B1 (en) * 1985-04-11 1987-09-18 Synthelabo NITROFURAN DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
HU197986B (en) * 1987-02-25 1989-07-28 Egyt Gyogyszervegyeszeti Gyar Process for producing veterinary preparation of synergic effect
US5883074A (en) * 1995-02-08 1999-03-16 Microcide Pharmaceuticals, Inc. Potentiators of antibacterial agents
WO1999039575A2 (en) * 1998-02-09 1999-08-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Synergistic biocidal activity of ternary complexes of negatively -charged biocides (component a), transition metal ions (component b), and neutral chelators (component c)

Also Published As

Publication number Publication date
JP2003527417A (en) 2003-09-16
WO2001070213A2 (en) 2001-09-27
US20030225126A1 (en) 2003-12-04
WO2001070213A3 (en) 2003-01-09
US20050043369A1 (en) 2005-02-24
EP1296688A2 (en) 2003-04-02

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