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AU2001250856A1 - Expression of recombinant human acetylcholinesterase in transgenic plants - Google Patents

Expression of recombinant human acetylcholinesterase in transgenic plants

Info

Publication number
AU2001250856A1
AU2001250856A1 AU2001250856A AU5085601A AU2001250856A1 AU 2001250856 A1 AU2001250856 A1 AU 2001250856A1 AU 2001250856 A AU2001250856 A AU 2001250856A AU 5085601 A AU5085601 A AU 5085601A AU 2001250856 A1 AU2001250856 A1 AU 2001250856A1
Authority
AU
Australia
Prior art keywords
expression
recombinant human
transgenic plants
human acetylcholinesterase
acetylcholinesterase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001250856A
Inventor
Charles Arntzen
Hugh Mason
Tsafrir Mor
Hermona Soreq
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boyce Thompson Institute for Plant Research Inc
Original Assignee
THOMPSON BOYCE PLANT RES
Boyce Thompson Institute for Plant Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by THOMPSON BOYCE PLANT RES, Boyce Thompson Institute for Plant Research Inc filed Critical THOMPSON BOYCE PLANT RES
Publication of AU2001250856A1 publication Critical patent/AU2001250856A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
AU2001250856A 2000-03-17 2001-03-16 Expression of recombinant human acetylcholinesterase in transgenic plants Abandoned AU2001250856A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19044000P 2000-03-17 2000-03-17
US60190440 2000-03-17
PCT/US2001/008468 WO2001071014A2 (en) 2000-03-17 2001-03-16 Expression of recombinant human acetylcholinesterase in transgenic plants

Publications (1)

Publication Number Publication Date
AU2001250856A1 true AU2001250856A1 (en) 2001-10-03

Family

ID=22701367

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001250856A Abandoned AU2001250856A1 (en) 2000-03-17 2001-03-16 Expression of recombinant human acetylcholinesterase in transgenic plants

Country Status (3)

Country Link
US (2) US6770799B2 (en)
AU (1) AU2001250856A1 (en)
WO (1) WO2001071014A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002353374A1 (en) * 2001-12-21 2003-07-09 Nexia Biotechnologies, Inc. Production of butyrylcholinesterases in transgenic mammals
WO2007040568A2 (en) 2004-12-01 2007-04-12 Arizona Board Of Regents, Acting For And On Behalf Of Arizona State Univeristy Production and use of human butyrylcholinesterase
US20090263370A1 (en) * 2006-11-30 2009-10-22 Guoliang Tao Methods for treating tachykinin-mediated diseases with cholinesterase
KR100973181B1 (en) 2007-11-13 2010-07-30 한국생명공학연구원 Qualitative analysis methods for LM watermelon using DIP-1 as an endogenous gene
AU2010234849B2 (en) 2009-03-30 2017-06-22 Mount Sinai School Of Medicine Influenza virus vaccines and uses thereof
JP5955219B2 (en) 2009-08-28 2016-07-20 アイカーン スクール オブ メディスン アット マウント シナイ Dose-escalating enzyme replacement therapy for acid sphingomyelinase deficiency
WO2011084145A2 (en) 2009-12-21 2011-07-14 Pharmathene, Inc. Recombinant butyrylcholinesterases and truncates thereof
EP3248615A1 (en) 2010-03-30 2017-11-29 Mount Sinai School of Medicine of New York University Influenza virus vaccines and uses thereof
US20140248684A1 (en) * 2011-09-16 2014-09-04 Arizona Board Of Regents For And On Behalf Of Arizona State University Compositions and methods for the production and use of human cholinesterases
BR112014006694A2 (en) 2011-09-20 2020-11-17 Mount Sinai School Of Medicine influenza vaccines and uses of these
CA2895508A1 (en) 2012-12-18 2014-06-26 Icahn School Of Medicine At Mount Sinai Influenza virus vaccines and uses thereof
WO2014159960A1 (en) 2013-03-14 2014-10-02 Icahn School Of Medicine At Mount Sinai Antibodies against influenza virus hemagglutinin and uses thereof
US10221402B2 (en) 2014-03-16 2019-03-05 Plantvax, Inc. Production of highly thermally stable recombinant cholinesterases for the detection, detoxification and decontamination of organophosphorus compounds
EP3247389A4 (en) 2015-01-23 2019-10-30 Icahn School of Medicine at Mount Sinai Influenza virus vaccination regimens
JP7237344B2 (en) 2016-06-15 2023-03-13 アイカーン スクール オブ メディシン アット マウント サイナイ Influenza virus hemagglutinin protein and uses thereof
CA3058652A1 (en) 2017-04-07 2018-10-11 Icahn School Of Medicine At Mount Sinai Anti-influenza b virus neuraminidase antibodies and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL75553A (en) * 1985-06-18 1993-07-08 Yeda Res & Dev Dna sequence coding for a cholinesterase-like peptide, peptides produced by cells containing said dna and antibodies thereto
US4956282A (en) * 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
IL89703A (en) * 1989-03-21 2001-10-31 Yissum Res Dev Co Polynucleotide encoding human acetylcholinesterase, vectors comprising said polynucleotide, cells transformed by said vectors, enzyme produced by said transformed cell, and uses thereof
IL101600A (en) * 1992-04-15 2000-02-29 Yissum Res Dev Co Synthetic partially phosphorothioated antisense oligodeoxynucleotides and pharmaceutical compositions containing them
US6025183A (en) * 1994-02-28 2000-02-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Transgenic animal assay system for anti-cholinesterase substances
US5932780A (en) * 1994-02-28 1999-08-03 Yissum Research Development Company Of Hebrew University Of Jerusalem Transgenic non-human animal assay system for anti-cholinesterase substances
WO1999053037A2 (en) * 1998-04-15 1999-10-21 Prodigene, Inc. Optimized nucleotide sequence encoding organophosphorous hydrolase and methods of use for same

Also Published As

Publication number Publication date
WO2001071014A2 (en) 2001-09-27
US6770799B2 (en) 2004-08-03
US20020162140A1 (en) 2002-10-31
WO2001071014A3 (en) 2002-05-30
US20040148657A1 (en) 2004-07-29

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