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AU2001246393A1 - Immunostimulating properties of a fragment of tgf-beta - Google Patents

Immunostimulating properties of a fragment of tgf-beta

Info

Publication number
AU2001246393A1
AU2001246393A1 AU2001246393A AU4639301A AU2001246393A1 AU 2001246393 A1 AU2001246393 A1 AU 2001246393A1 AU 2001246393 A AU2001246393 A AU 2001246393A AU 4639301 A AU4639301 A AU 4639301A AU 2001246393 A1 AU2001246393 A1 AU 2001246393A1
Authority
AU
Australia
Prior art keywords
tgf
fragment
beta
immunostimulating properties
immunostimulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001246393A
Inventor
Peter Kaastrup
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VACCINE CHIP TECHNOLOGY APS
Original Assignee
VACCINE CHIP TECHNOLOGY APS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VACCINE CHIP TECHNOLOGY APS filed Critical VACCINE CHIP TECHNOLOGY APS
Publication of AU2001246393A1 publication Critical patent/AU2001246393A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2001246393A 2000-03-31 2001-03-30 Immunostimulating properties of a fragment of tgf-beta Abandoned AU2001246393A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200000540 2000-03-31
DKPA200000540 2000-03-31
US24697300P 2000-11-13 2000-11-13
US60246973 2000-11-13
PCT/DK2001/000218 WO2001072331A1 (en) 2000-03-31 2001-03-30 Immunostimulating properties of a fragment of tgf-beta

Publications (1)

Publication Number Publication Date
AU2001246393A1 true AU2001246393A1 (en) 2001-10-08

Family

ID=26068804

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001246393A Abandoned AU2001246393A1 (en) 2000-03-31 2001-03-30 Immunostimulating properties of a fragment of tgf-beta

Country Status (4)

Country Link
US (1) US20020160012A1 (en)
EP (1) EP1292330A1 (en)
AU (1) AU2001246393A1 (en)
WO (1) WO2001072331A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10026713A1 (en) * 2000-05-30 2001-12-06 Walter Sebald Mutein a chain of a protein from the superfamily of the growth factor TGF-beta
EP1377320B1 (en) 2001-04-04 2008-10-01 Nordic Vaccine Technology A/S Polynucleotide binding complexes comprising sterols and saponins
AU2004224317B2 (en) * 2003-03-21 2009-11-12 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Finding usable portion of sigmoid curve
CN103864893B (en) * 2007-07-27 2017-01-04 伊玛提克斯生物技术有限公司 The immunogenic epitopes of immunotherapy
GB201908012D0 (en) * 2019-06-05 2019-07-17 Io Biotech Aps TGF-Beta vaccine

Family Cites Families (37)

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DE3588058T3 (en) * 1984-07-16 2005-04-07 Celtrix Pharmaceuticals, Inc., Palo Alto Cartilage-inducing polypeptide factors from bone
IT1200103B (en) * 1984-08-14 1989-01-05 Sandoz Ag N-SUBSTITUTED TETRAALKYLPYRIDIN COMPOUNDS AGENTS AS LIGHT STABILIZERS FOR POLYMERIC MATERIALS
US5116943A (en) * 1985-01-18 1992-05-26 Cetus Corporation Oxidation-resistant muteins of Il-2 and other protein
US4886747A (en) * 1985-03-22 1989-12-12 Genentech, Inc. Nucleic acid encoding TGF-β and its uses
US4894332A (en) * 1985-03-27 1990-01-16 Biogen, Inc. DNA sequences coding for Mycoplasma hypopneumoniae surface antigens, methods of use to make the corresponding proteins
US5194254A (en) * 1986-05-06 1993-03-16 Connaught Laboratories Limited Enhancement of antigen immunogenicity
US5019384A (en) * 1986-06-30 1991-05-28 Massachusetts Institute Of Technology Immunonodulating compositions and their use
US5554372A (en) * 1986-09-22 1996-09-10 Emory University Methods and vaccines comprising surface-active copolymers
US5976541A (en) * 1988-01-26 1999-11-02 The United States Of America As Represented By The Department Of Health And Human Services Potent peptide for stimulation of cytotoxic T lymphocytes specific for the HIV-1 envelope
WO1988005787A1 (en) * 1987-01-30 1988-08-11 Techne Corporation Transforming growth factor-beta
AU1539188A (en) * 1987-05-04 1988-11-10 Bristol-Myers Squibb Company TGF-B2 and novel compositions having anti-neoplastic activity
US6780613B1 (en) * 1988-10-28 2004-08-24 Genentech, Inc. Growth hormone variants
US5118791A (en) * 1989-05-25 1992-06-02 Genentech, Inc. Biologically active polypeptides based on transforming growth factor-β
US5061786A (en) * 1989-05-25 1991-10-29 Genentech, Inc. Biologically active polypeptides based on transforming growth factor-β
US5268455A (en) * 1989-05-25 1993-12-07 Genentech, Inc. Process for making biologically active polypeptides based on transforming growth factor-βsequences
US5837269A (en) * 1989-09-25 1998-11-17 University Of Utah Research Foundation Vaccine compositions and method for enhancing an immune response
GB9112553D0 (en) * 1991-06-11 1991-07-31 Wellcome Found Fusion proteins
US5202119A (en) * 1991-06-28 1993-04-13 Genentech, Inc. Method of stimulating immune response
US5904920A (en) * 1991-10-04 1999-05-18 Whitehead Institute For Biomedical Research Regulation of systemic immune responses utilizing cytokines and antigens
US6171584B1 (en) * 1992-02-12 2001-01-09 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh Method of treatment with growth/differentiation factors of the TGF-β family
US5980899A (en) * 1992-06-10 1999-11-09 The United States Of America As Represented By The Department Of Health And Human Services Identification of peptides that stimulate hepatitis C virus specific cytotoxic T cells
US5420243A (en) * 1993-01-26 1995-05-30 Celtrix Pharmaceuticals, Inc. Biologically active TGF-β2 peptides
CN1079830C (en) * 1993-04-20 2002-02-27 索利斯治疗学公司 Methods and materials for treatment of individuals infected with intracellular infectious agents
US5759551A (en) * 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
EP0708659A4 (en) * 1993-06-07 2000-08-23 Genentech Inc Hiv envelope polypeptides
US5453492A (en) * 1993-07-28 1995-09-26 La Jolla Cancer Research Foundation 60 kDa transforming growth factor-β-binding protein and its use to detect or purify TGF-β
US5603933A (en) * 1993-08-31 1997-02-18 Board Of Regents, The University Of Texas CD4 peptides for binding to viral envelope proteins
US6015686A (en) * 1993-09-15 2000-01-18 Chiron Viagene, Inc. Eukaryotic layered vector initiation systems
US5874085A (en) * 1993-11-10 1999-02-23 Henry M. Jackson Foundation For The Advancement Of Military Medicine Vaccine for enhanced production of IgA antibodies
US5961979A (en) * 1994-03-16 1999-10-05 Mount Sinai School Of Medicine Of The City University Of New York Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens
US5876735A (en) * 1994-04-22 1999-03-02 Corixa Corporation Methods for enhancement of protective immune responses
US6013268A (en) * 1994-04-22 2000-01-11 Corixa Corporation Methods for enhancement of protective immune responses
US5772995A (en) * 1994-07-18 1998-06-30 Sidney Kimmel Cancer Center Compositions and methods for enhanced tumor cell immunity in vivo
TW440566B (en) * 1994-07-25 2001-06-16 Novartis Ag Novel process for the production of biologically active dimeric protein
GB9425582D0 (en) * 1994-12-19 1995-02-15 Iaf Biochem Int Peptides having immunomodulatory activity
US5900238A (en) * 1995-07-27 1999-05-04 Immunex Corporation Vaccine delivery system
US5972655A (en) * 1998-11-19 1999-10-26 The Research Foundation Of State University Of New York Y2H61 an IKK binding protein

Also Published As

Publication number Publication date
EP1292330A1 (en) 2003-03-19
US20020160012A1 (en) 2002-10-31
WO2001072331A1 (en) 2001-10-04

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