[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

AU2052497A - Biotin-containing compounds, biotinylation reagents and methods - Google Patents

Biotin-containing compounds, biotinylation reagents and methods

Info

Publication number
AU2052497A
AU2052497A AU20524/97A AU2052497A AU2052497A AU 2052497 A AU2052497 A AU 2052497A AU 20524/97 A AU20524/97 A AU 20524/97A AU 2052497 A AU2052497 A AU 2052497A AU 2052497 A AU2052497 A AU 2052497A
Authority
AU
Australia
Prior art keywords
biotin
methods
containing compounds
biotinylation reagents
biotinylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU20524/97A
Inventor
Donald K. Hamlin
Pradip M Pathare
S. Ananda Weerawarna
Scott D. Wilbur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington
Original Assignee
University of Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington filed Critical University of Washington
Publication of AU2052497A publication Critical patent/AU2052497A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/555Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells
    • A61K47/557Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells the modifying agent being biotin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6891Pre-targeting systems involving an antibody for targeting specific cells
    • A61K47/6893Pre-targeting systems involving an antibody for targeting specific cells clearing therapy or enhanced clearance, i.e. using an antibody clearing agents in addition to T-A and D-M
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A61K49/0043Fluorescein, used in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/005Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0052Small organic molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU20524/97A 1996-02-08 1997-02-07 Biotin-containing compounds, biotinylation reagents and methods Abandoned AU2052497A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1132196P 1996-02-08 1996-02-08
US011321 1996-02-08
PCT/US1997/002560 WO1997029114A1 (en) 1996-02-08 1997-02-07 Biotin-containing compounds, biotinylation reagents and methods

Publications (1)

Publication Number Publication Date
AU2052497A true AU2052497A (en) 1997-08-28

Family

ID=21749866

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20524/97A Abandoned AU2052497A (en) 1996-02-08 1997-02-07 Biotin-containing compounds, biotinylation reagents and methods

Country Status (2)

Country Link
AU (1) AU2052497A (en)
WO (1) WO1997029114A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846741A (en) * 1992-08-21 1998-12-08 Immunomedics, Inc. Boron neutron capture therapy using pre-targeting methods
US6228362B1 (en) * 1992-08-21 2001-05-08 Immunomedics, Inc. Boron neutron capture therapy using pre-targeting methods
ATE458499T1 (en) * 1995-06-07 2010-03-15 Immunomedics Inc IMPROVED DELIVERY OF DIAGNOSTIC AND THERAPEUTIC SUBSTANCES AT A DESTINATION
US20010023288A1 (en) 1999-07-07 2001-09-20 Wilbur D. Scott Trifunctional reagent for conjugation to a biomolecule
WO2000002050A1 (en) * 1998-07-07 2000-01-13 Department Of Radiation Oncology, University Of Washington Trifunctional reagent for conjugation to a biomolecule
EP1196199A4 (en) * 1999-06-02 2002-06-19 Univ Washington Water soluble multi-biotin-containing compounds
AU2001274761B2 (en) * 2000-06-16 2005-06-16 Mitra Medical Technology Ab Reuseable extracorporeal colums loaded with ligand-dibiotin conjugates
SE0002287D0 (en) 2000-06-16 2000-06-16 Department Of Radiation Oncolo biotin
WO2002042427A2 (en) * 2000-10-25 2002-05-30 Surromed, Inc. Mass tags for quantitative analysis
US20040132092A1 (en) * 2003-01-03 2004-07-08 Stetson Christopher M. Determining the density of functional moieties on polymer reagents
EP1684810B1 (en) 2003-10-02 2013-09-25 The General Hospital Corporation Polybiotin compounds for magnetic resonance imaging and drug delivery
EP2371967B1 (en) 2005-03-18 2015-06-03 DSM IP Assets B.V. Production of carotenoids in oleaginous yeast and fungi
CZ302669B6 (en) * 2010-03-29 2011-08-24 Univerzita Palackého v Olomouci Efficient method of biotinylation of amino compounds using solid phase synthesis for affinity chromatography needs
CZ302510B6 (en) * 2010-03-29 2011-06-22 Univerzita Palackého v Olomouci Efficient method of biotinylation of compounds containing carboxyl group using solid phase synthesis for affinity chromatography needs
WO2013036826A2 (en) * 2011-09-09 2013-03-14 The Trustees Of Columbia University In The City Of New York Streptavidin complexes and uses thereof
US8927732B2 (en) * 2012-03-30 2015-01-06 General Electric Company Biotin stannane for HPLC-free radioiodination
DK3154587T3 (en) 2014-06-13 2020-03-09 Tenboron Oy CONJUGATES INCLUDING AN ANTI-EGFR1 ANTIBODY
EP3978027A4 (en) * 2019-05-31 2023-10-11 D&D Pharmatech Inc. Physiologically active substance bound to biotin moiety, and composition for oral administration including same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5482698A (en) * 1993-04-22 1996-01-09 Immunomedics, Inc. Detection and therapy of lesions with biotin/avidin polymer conjugates

Also Published As

Publication number Publication date
WO1997029114A1 (en) 1997-08-14

Similar Documents

Publication Publication Date Title
AU5551796A (en) Sample preprocessor
AU8908998A (en) Analyte detection systems
AU9586798A (en) Analyte assaying device
AU2245997A (en) Mutivariate sample analysis
AU6684496A (en) Ultra-wideband directional sampler
AU4859797A (en) Nanoparticles biosensor
AU2052497A (en) Biotin-containing compounds, biotinylation reagents and methods
AU6264398A (en) Schottky-metal detection method
AU3185199A (en) Immunoassay device and method
AU3506597A (en) Sampler
AU8548498A (en) Enhanced detection method
AU8358398A (en) Immunoassay apparatus
AU2752897A (en) Formazan-based immunoassay
AU1284899A (en) Sample retrieval system
AU3326597A (en) Immunoassay method
AU3166897A (en) Factor vii-binding reagent
AU4159697A (en) Interaction trap assay, reagents and uses thereof
AU4996796A (en) Rapid, self-performing tsh immunoassay
AUPP403098A0 (en) Method and system for selection candidates for employment
AU8133798A (en) Sorting device
AU3254799A (en) Sorting wc-accession
AU5292196A (en) Drilling device
AU7146198A (en) Method for fertility detection
AU3432597A (en) Sampler for liquids
ZA977188B (en) Immunoassay method.