AU2052497A - Biotin-containing compounds, biotinylation reagents and methods - Google Patents
Biotin-containing compounds, biotinylation reagents and methodsInfo
- Publication number
- AU2052497A AU2052497A AU20524/97A AU2052497A AU2052497A AU 2052497 A AU2052497 A AU 2052497A AU 20524/97 A AU20524/97 A AU 20524/97A AU 2052497 A AU2052497 A AU 2052497A AU 2052497 A AU2052497 A AU 2052497A
- Authority
- AU
- Australia
- Prior art keywords
- biotin
- methods
- containing compounds
- biotinylation reagents
- biotinylation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 title 2
- 229960002685 biotin Drugs 0.000 title 1
- 235000020958 biotin Nutrition 0.000 title 1
- 239000011616 biotin Substances 0.000 title 1
- 230000006287 biotinylation Effects 0.000 title 1
- 238000007413 biotinylation Methods 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
- A61K41/0095—Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/555—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells
- A61K47/557—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells the modifying agent being biotin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
- A61K47/6893—Pre-targeting systems involving an antibody for targeting specific cells clearing therapy or enhanced clearance, i.e. using an antibody clearing agents in addition to T-A and D-M
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
- A61K49/0043—Fluorescein, used in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0052—Small organic molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Nanotechnology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1132196P | 1996-02-08 | 1996-02-08 | |
US011321 | 1996-02-08 | ||
PCT/US1997/002560 WO1997029114A1 (en) | 1996-02-08 | 1997-02-07 | Biotin-containing compounds, biotinylation reagents and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2052497A true AU2052497A (en) | 1997-08-28 |
Family
ID=21749866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU20524/97A Abandoned AU2052497A (en) | 1996-02-08 | 1997-02-07 | Biotin-containing compounds, biotinylation reagents and methods |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2052497A (en) |
WO (1) | WO1997029114A1 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5846741A (en) * | 1992-08-21 | 1998-12-08 | Immunomedics, Inc. | Boron neutron capture therapy using pre-targeting methods |
US6228362B1 (en) * | 1992-08-21 | 2001-05-08 | Immunomedics, Inc. | Boron neutron capture therapy using pre-targeting methods |
ATE458499T1 (en) * | 1995-06-07 | 2010-03-15 | Immunomedics Inc | IMPROVED DELIVERY OF DIAGNOSTIC AND THERAPEUTIC SUBSTANCES AT A DESTINATION |
US20010023288A1 (en) | 1999-07-07 | 2001-09-20 | Wilbur D. Scott | Trifunctional reagent for conjugation to a biomolecule |
WO2000002050A1 (en) * | 1998-07-07 | 2000-01-13 | Department Of Radiation Oncology, University Of Washington | Trifunctional reagent for conjugation to a biomolecule |
EP1196199A4 (en) * | 1999-06-02 | 2002-06-19 | Univ Washington | Water soluble multi-biotin-containing compounds |
AU2001274761B2 (en) * | 2000-06-16 | 2005-06-16 | Mitra Medical Technology Ab | Reuseable extracorporeal colums loaded with ligand-dibiotin conjugates |
SE0002287D0 (en) | 2000-06-16 | 2000-06-16 | Department Of Radiation Oncolo | biotin |
WO2002042427A2 (en) * | 2000-10-25 | 2002-05-30 | Surromed, Inc. | Mass tags for quantitative analysis |
US20040132092A1 (en) * | 2003-01-03 | 2004-07-08 | Stetson Christopher M. | Determining the density of functional moieties on polymer reagents |
EP1684810B1 (en) | 2003-10-02 | 2013-09-25 | The General Hospital Corporation | Polybiotin compounds for magnetic resonance imaging and drug delivery |
EP2371967B1 (en) | 2005-03-18 | 2015-06-03 | DSM IP Assets B.V. | Production of carotenoids in oleaginous yeast and fungi |
CZ302669B6 (en) * | 2010-03-29 | 2011-08-24 | Univerzita Palackého v Olomouci | Efficient method of biotinylation of amino compounds using solid phase synthesis for affinity chromatography needs |
CZ302510B6 (en) * | 2010-03-29 | 2011-06-22 | Univerzita Palackého v Olomouci | Efficient method of biotinylation of compounds containing carboxyl group using solid phase synthesis for affinity chromatography needs |
WO2013036826A2 (en) * | 2011-09-09 | 2013-03-14 | The Trustees Of Columbia University In The City Of New York | Streptavidin complexes and uses thereof |
US8927732B2 (en) * | 2012-03-30 | 2015-01-06 | General Electric Company | Biotin stannane for HPLC-free radioiodination |
DK3154587T3 (en) | 2014-06-13 | 2020-03-09 | Tenboron Oy | CONJUGATES INCLUDING AN ANTI-EGFR1 ANTIBODY |
EP3978027A4 (en) * | 2019-05-31 | 2023-10-11 | D&D Pharmatech Inc. | Physiologically active substance bound to biotin moiety, and composition for oral administration including same |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5482698A (en) * | 1993-04-22 | 1996-01-09 | Immunomedics, Inc. | Detection and therapy of lesions with biotin/avidin polymer conjugates |
-
1997
- 1997-02-07 AU AU20524/97A patent/AU2052497A/en not_active Abandoned
- 1997-02-07 WO PCT/US1997/002560 patent/WO1997029114A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO1997029114A1 (en) | 1997-08-14 |
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