ATE99331T1 - Fusionsproteine und herstellung davon. - Google Patents
Fusionsproteine und herstellung davon.Info
- Publication number
- ATE99331T1 ATE99331T1 AT90116878T AT90116878T ATE99331T1 AT E99331 T1 ATE99331 T1 AT E99331T1 AT 90116878 T AT90116878 T AT 90116878T AT 90116878 T AT90116878 T AT 90116878T AT E99331 T1 ATE99331 T1 AT E99331T1
- Authority
- AT
- Austria
- Prior art keywords
- fused protein
- protein
- producing
- heat
- recombinant dna
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 102000037865 fusion proteins Human genes 0.000 title 1
- 108020001507 fusion proteins Proteins 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 11
- 102000004169 proteins and genes Human genes 0.000 abstract 11
- 108020004511 Recombinant DNA Proteins 0.000 abstract 3
- 101000867232 Escherichia coli Heat-stable enterotoxin II Proteins 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 101710146739 Enterotoxin Proteins 0.000 abstract 1
- 241000700584 Simplexvirus Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 125000002091 cationic group Chemical group 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 239000000147 enterotoxin Substances 0.000 abstract 1
- 231100000655 enterotoxin Toxicity 0.000 abstract 1
- 238000005227 gel permeation chromatography Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23372889 | 1989-09-08 | ||
| EP90116878A EP0418626B1 (de) | 1989-09-08 | 1990-09-03 | Fusionsproteine und Herstellung davon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE99331T1 true ATE99331T1 (de) | 1994-01-15 |
Family
ID=16959644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90116878T ATE99331T1 (de) | 1989-09-08 | 1990-09-03 | Fusionsproteine und herstellung davon. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0418626B1 (de) |
| JP (1) | JPH03178995A (de) |
| AT (1) | ATE99331T1 (de) |
| CA (1) | CA2024918A1 (de) |
| DE (1) | DE69005572T2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2050425A1 (en) * | 1990-09-03 | 1992-03-04 | Yoshiaki Uda | Pharmaceutical composition and its mucous use |
| GB9316745D0 (en) * | 1993-08-12 | 1993-09-29 | Medeva Holdings Bv | Vaccine compositions |
| US5681571A (en) * | 1993-10-08 | 1997-10-28 | Duotol Ab | Immunological tolerance-inducing agent |
| CN1173204A (zh) * | 1994-11-17 | 1998-02-11 | 马克西姆药物公司 | 刺激粘膜免疫的免疫原 |
| CA2227871A1 (en) * | 1995-07-26 | 1997-02-13 | Maxim Pharmaceuticals, Inc. | Mucosal delivery of polynucleotides |
| CU22629A1 (es) * | 1997-03-06 | 2000-12-22 | Ct Ingenieria Genetica Biotech | Formulaciones inmunopotenciadoras para uso vacunal |
| JP4623625B2 (ja) * | 2003-07-24 | 2011-02-02 | 株式会社ＡＭＢｉＳ | ヘテロ型５量体組換えワクチン |
| CN100334212C (zh) * | 2005-07-25 | 2007-08-29 | 华东理工大学 | 一种用于原核分泌、融合表达大肠杆菌热敏毒素b亚单位的载体 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL78775A (en) * | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
| US5109113A (en) * | 1986-05-02 | 1992-04-28 | Genentech, Inc. | Membrane anchor fusion polypeptides |
| US5112749A (en) * | 1987-10-02 | 1992-05-12 | Praxis Biologics, Inc. | Vaccines for the malaria circumsporozoite protein |
| AU4754490A (en) * | 1988-12-07 | 1990-06-26 | University Of Leicester | Heat-labile toxin b subunit fusion proteins |
-
1990
- 1990-09-03 EP EP90116878A patent/EP0418626B1/de not_active Expired - Lifetime
- 1990-09-03 AT AT90116878T patent/ATE99331T1/de active
- 1990-09-03 DE DE90116878T patent/DE69005572T2/de not_active Expired - Fee Related
- 1990-09-07 JP JP2235613A patent/JPH03178995A/ja active Pending
- 1990-09-07 CA CA002024918A patent/CA2024918A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2024918A1 (en) | 1991-03-09 |
| JPH03178995A (ja) | 1991-08-02 |
| DE69005572T2 (de) | 1994-04-07 |
| EP0418626B1 (de) | 1993-12-29 |
| EP0418626A3 (en) | 1991-09-25 |
| DE69005572D1 (de) | 1994-02-10 |
| EP0418626A2 (de) | 1991-03-27 |
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