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ATE78473T1 - Verfahren zur herstellung von 2,4-diamino-6-(1piperidinyl)-pyramidin-n-oxid. - Google Patents

Verfahren zur herstellung von 2,4-diamino-6-(1piperidinyl)-pyramidin-n-oxid.

Info

Publication number
ATE78473T1
ATE78473T1 AT88830189T AT88830189T ATE78473T1 AT E78473 T1 ATE78473 T1 AT E78473T1 AT 88830189 T AT88830189 T AT 88830189T AT 88830189 T AT88830189 T AT 88830189T AT E78473 T1 ATE78473 T1 AT E78473T1
Authority
AT
Austria
Prior art keywords
diamino
oxide
chem
preparation
pyramidine
Prior art date
Application number
AT88830189T
Other languages
English (en)
Inventor
Claudio Botre
Original Assignee
Serono Ist Farm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serono Ist Farm filed Critical Serono Ist Farm
Application granted granted Critical
Publication of ATE78473T1 publication Critical patent/ATE78473T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT88830189T 1987-05-08 1988-05-03 Verfahren zur herstellung von 2,4-diamino-6-(1piperidinyl)-pyramidin-n-oxid. ATE78473T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8720436A IT1212140B (it) 1987-05-08 1987-05-08 Processo per la preparazione del 2,4-diammino-6-(1-piperidinil)-piri mi-din-n-ossido.
EP88830189A EP0295218B1 (de) 1987-05-08 1988-05-03 Verfahren zur Herstellung von 2,4-Diamino-6-(1-piperidinyl)-pyramidin-N-oxid

Publications (1)

Publication Number Publication Date
ATE78473T1 true ATE78473T1 (de) 1992-08-15

Family

ID=11166913

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88830189T ATE78473T1 (de) 1987-05-08 1988-05-03 Verfahren zur herstellung von 2,4-diamino-6-(1piperidinyl)-pyramidin-n-oxid.

Country Status (7)

Country Link
EP (1) EP0295218B1 (de)
AT (1) ATE78473T1 (de)
BE (1) BE1000745A4 (de)
DE (1) DE3872956T2 (de)
ES (1) ES2042799T3 (de)
GR (1) GR3006050T3 (de)
IT (1) IT1212140B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI367208B (en) 2004-11-12 2012-07-01 Sumitomo Chemical Co Production method of pyrimidine compounds
GB2451594A (en) * 2006-03-15 2009-02-04 Csir Modulation of phosphoryl transferase activity of glutamine synthetase
CN101438288A (zh) * 2006-03-15 2009-05-20 Csir公司 谷氨酰胺合成酶的磷酰基转移酶活性的调节
CN107235919B (zh) * 2017-06-22 2020-05-12 安徽拜善晟制药有限公司 一种米诺地尔的合成工艺
CN110272391B (zh) * 2019-07-03 2022-10-28 天津药物研究院药业有限责任公司 一种米诺地尔的精制方法
CN114394941A (zh) * 2022-02-16 2022-04-26 汉瑞药业(荆门)有限公司 一种2,4-二氨基-6-氯嘧啶的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3382248A (en) * 1965-11-01 1968-05-07 Upjohn Co 6-amino-4, 5-di(substituted amino)-1, 2-dihydro-1-hydroxy-2-iminopyrimidines

Also Published As

Publication number Publication date
ES2042799T3 (es) 1993-12-16
DE3872956T2 (de) 1992-12-03
BE1000745A4 (fr) 1989-03-28
IT8720436A0 (it) 1987-05-08
IT1212140B (it) 1989-11-08
DE3872956D1 (de) 1992-08-27
EP0295218B1 (de) 1992-07-22
GR3006050T3 (de) 1993-06-21
EP0295218A1 (de) 1988-12-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee