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ATE517899T1 - Hiv-integrasehemmer - Google Patents

Hiv-integrasehemmer

Info

Publication number
ATE517899T1
ATE517899T1 AT06792296T AT06792296T ATE517899T1 AT E517899 T1 ATE517899 T1 AT E517899T1 AT 06792296 T AT06792296 T AT 06792296T AT 06792296 T AT06792296 T AT 06792296T AT E517899 T1 ATE517899 T1 AT E517899T1
Authority
AT
Austria
Prior art keywords
compounds
hiv
inhibitors
hiv integrase
integrase inhibitors
Prior art date
Application number
AT06792296T
Other languages
English (en)
Inventor
Monica Donghi
Vincenzo Summa
Olaf Kinzel
Original Assignee
Angeletti P Ist Richerche Bio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeletti P Ist Richerche Bio filed Critical Angeletti P Ist Richerche Bio
Application granted granted Critical
Publication of ATE517899T1 publication Critical patent/ATE517899T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06792296T 2005-10-04 2006-09-26 Hiv-integrasehemmer ATE517899T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72356705P 2005-10-04 2005-10-04
PCT/EP2006/009410 WO2007039218A1 (en) 2005-10-04 2006-09-26 Hiv integrase inhibitors

Publications (1)

Publication Number Publication Date
ATE517899T1 true ATE517899T1 (de) 2011-08-15

Family

ID=37621988

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06792296T ATE517899T1 (de) 2005-10-04 2006-09-26 Hiv-integrasehemmer

Country Status (7)

Country Link
US (1) US7939537B2 (de)
EP (1) EP1937678B1 (de)
JP (1) JP5094725B2 (de)
AT (1) ATE517899T1 (de)
AU (1) AU2006299042B8 (de)
CA (1) CA2622639C (de)
WO (1) WO2007039218A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR064517A1 (es) 2006-12-22 2009-04-08 Avexa Ltd Pirimidinionas biciclicas y sus usos
EP2079737A1 (de) * 2007-02-05 2009-07-22 Xenon Pharmaceuticals Inc. Für die behandlung von über natriumkanäle vermittelten krankheiten oder leiden geeignete pyridopyrimidinonverbindungen
JP5269086B2 (ja) 2007-11-15 2013-08-21 ギリアード サイエンシス インコーポレーテッド ヒト免疫不全ウイルスの複製阻害薬
WO2009062288A1 (en) 2007-11-15 2009-05-22 Boehringer Ingelheim International Gmbh Inhibitors of human immunodeficiency virus replication
EA201200631A1 (ru) 2007-11-16 2012-11-30 Джилид Сайенсиз, Инк. Ингибиторы репликации вируса иммунодефицита человека
CA2729663A1 (en) * 2008-07-02 2010-01-07 Avexa Limited Compounds having antiviral properties
CN102336751A (zh) * 2010-07-16 2012-02-01 爱维艾珂瑟有限公司 新型抗病毒剂
CA3131037A1 (en) 2011-11-30 2013-06-06 Emory University Antiviral jak inhibitors useful in treating or preventing retroviral and other viral infections
CN115151540A (zh) 2019-12-02 2022-10-04 风暴治疗有限公司 作为mettl3抑制剂的多杂环化合物

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0017676D0 (en) 2000-07-19 2000-09-06 Angeletti P Ist Richerche Bio Inhibitors of viral polymerase
JP4252797B2 (ja) 2000-10-12 2009-04-08 メルク エンド カムパニー インコーポレーテッド Ｈｉｖインテグラーゼ阻害薬として有用なアザ−およびポリアザ−ナフタレニルカルボキサミド類
WO2002036734A2 (en) 2000-10-12 2002-05-10 Merck & Co., Inc. Aza-and polyaza-naphthalenyl ketones useful as hiv integrase inhibitors
WO2002055079A2 (en) 2000-10-12 2002-07-18 Merck & Co Inc Aza-and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors
ATE364385T1 (de) 2000-10-12 2007-07-15 Merck & Co Inc Aza- und polyaza-naphthalenylcarbonsäureamide als hiv-integrase-hemmer
JP3616628B2 (ja) * 2001-03-01 2005-02-02 塩野義製薬株式会社 Ｈｉｖインテグラーゼ阻害活性を有する含窒素芳香族複素環化合物
BR0211750A (pt) 2001-08-10 2004-10-13 Shionogi & Co Agente antiviral
CN102219750B (zh) 2001-10-26 2013-05-29 P.安杰莱蒂分子生物学研究所 关于hiv整合酶的n-取代的羟基嘧啶酮甲酰胺抑制剂
US7232819B2 (en) 2001-10-26 2007-06-19 Istituto Di Ricerche Di Biologia P. Angeletti S.P.A. Dihydroxypyrimidine carboxamide inhibitors of HIV integrase
JP4170633B2 (ja) * 2001-11-12 2008-10-22 独立行政法人科学技術振興機構 拡張型心筋症の原因となる新規点突然変異を有するデスミン遺伝子
CA2472372C (en) 2002-01-17 2010-08-17 Melissa Egbertson Hydroxynaphthyridinone carboxamides useful as hiv integrase inhibitors
GB0201179D0 (en) 2002-01-18 2002-03-06 Angeletti P Ist Richerche Bio Therapeutic agents
US7109186B2 (en) 2002-07-09 2006-09-19 Bristol-Myers Squibb Company HIV integrase inhibitors
NZ540729A (en) * 2002-12-27 2008-03-28 Angeletti P Ist Richerche Bio Tetrahydro-4H-pyrido[1,2-a]pyrimidines and related compounds useful as HIV integrase inhibitors
TW200510425A (en) 2003-08-13 2005-03-16 Japan Tobacco Inc Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor
TW200526635A (en) * 2003-12-22 2005-08-16 Shionogi & Co Hydroxypyrimidinone derivative having HIV integrase inhibitory activity
US7598264B2 (en) 2004-03-09 2009-10-06 Merck & Co., Inc. HIV integrase inhibitors
AU2005221864A1 (en) 2004-03-09 2005-09-22 Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa HIV integrase inhibitors
EP1725535A4 (de) 2004-03-09 2009-11-25 Merck & Co Inc Hiv-integrasehemmer
US7176196B2 (en) 2004-05-28 2007-02-13 Bristol-Myers Squibb Company Bicyclic heterocycles as HIV integrase inhibitors
US7192948B2 (en) 2004-05-28 2007-03-20 Bristol-Myers Squibb Company Bicyclic heterocycles as HIV integrase inhibitors
SI3045206T1 (en) 2005-04-28 2018-07-31 Viiv Healthcare Company A polycyclic carbamoylpyridone derivative with inhibitory activity for the HIV integrase

Also Published As

Publication number Publication date
EP1937678B1 (de) 2011-07-27
JP2009510148A (ja) 2009-03-12
WO2007039218A1 (en) 2007-04-12
AU2006299042B8 (en) 2011-09-15
CA2622639C (en) 2012-01-03
JP5094725B2 (ja) 2012-12-12
AU2006299042A1 (en) 2007-04-12
EP1937678A1 (de) 2008-07-02
US20090221571A1 (en) 2009-09-03
CA2622639A1 (en) 2007-04-12
AU2006299042A8 (en) 2011-09-15
US7939537B2 (en) 2011-05-10
AU2006299042B2 (en) 2011-09-01

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties