ATE509931T1 - Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafür - Google Patents

Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafür

Info

Publication number: ATE509931T1
Authority: AT; Austria
Prior art keywords: methods; derivatives; azaadamantanester; carbamat; application
Prior art date: 2007-03-23

Application number

AT08732552T

Other languages

English (en)

Inventor

Michael R Schrimpf

Diana L Nersesian

Kevin B Sippy

Jianguo Ji

Tao Li

Lei Shi

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-03-23

Filing date

2008-03-20

Publication date

2011-06-15

2008-03-20 Application filed by Abbott Lab filed Critical Abbott Lab

2011-06-15 Application granted granted Critical

2011-06-15 Publication of ATE509931T1 publication Critical patent/ATE509931T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Virology (AREA)
Orthopedic Medicine & Surgery (AREA)
Addiction (AREA)
Psychology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Oncology (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT08732552T 2007-03-23 2008-03-20 Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafür ATE509931T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US89674507P	2007-03-23	2007-03-23
PCT/US2008/057641 WO2008118742A1 (en)	2007-03-23	2008-03-20	Azaadamantane ester and carbamate derivatives and methods of use thereof

Publications (1)

Publication Number	Publication Date
ATE509931T1 true ATE509931T1 (de)	2011-06-15

Family

ID=39788934

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT08732552T ATE509931T1 (de)	2007-03-23	2008-03-20	Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafür

Country Status (10)

Country	Link
US (2)	US8163916B2 (de)
EP (1)	EP2129672B1 (de)
JP (2)	JP5566698B2 (de)
CN (2)	CN101641355A (de)
AT (1)	ATE509931T1 (de)
CA (1)	CA2679870A1 (de)
ES (1)	ES2363998T3 (de)
HK (1)	HK1133642A1 (de)
MX (1)	MX2009010174A (de)
WO (1)	WO2008118742A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8314119B2 (en)	2006-11-06	2012-11-20	Abbvie Inc.	Azaadamantane derivatives and methods of use
WO2010145208A1 (en) *	2009-06-19	2010-12-23	Abbott Laboratories	Diazahomoadamantane derivatives and methods of use thereof
EP2389922A1 (de) *	2010-05-25	2011-11-30	Symrise AG	Cyclohexylcarbamatverbindungen als Anti-ageing-Wirkstoffe
EP2593077B1 (de)	2010-05-25	2016-11-02	Symrise AG	Cyclohexyl-carbamatverbindungen als haut- und/oder haaraufheller
KR101778547B1 (ko) *	2010-05-25	2017-09-15	시므라이즈 아게	항-셀룰라이트 성분으로서의 사이클로헥실 카바메이트 화합물
SG2014013460A (en)	2010-09-23	2014-09-26	Abbvie Inc	Monohydrate of an azaadamantane derivative
WO2014164682A1 (en)	2013-03-12	2014-10-09	Abbvie Inc.	Azaadamantane formate ester and process preparing azaadamantane derivatives
TW201617342A (zh)	2014-07-11	2016-05-16	阿法馬根公司	調節α７活性之啶類
US10183938B2 (en)	2014-12-16	2019-01-22	Axovant Sciences Gmbh	Geminal substituted quinuclidine amide compounds as agonists of α-7 nicotonic acetylcholine receptors
CA2988968A1 (en)	2015-06-10	2016-12-15	Forum Pharmaceuticals, Inc.	Aminobenzisoxazole compounds as agonists of a7-nicotinic acetylcholine receptors
US10428062B2 (en)	2015-08-12	2019-10-01	Axovant Sciences Gmbh	Geminal substituted aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8523211D0 (en)	1985-09-19	1985-10-23	Beecham Group Plc	Compounds
NL8701682A (nl) *	1986-07-30	1988-02-16	Sandoz Ag	Werkwijze voor het therapeutisch toepassen van serotonine antagonisten, aktieve verbindingen en farmaceutische preparaten die deze verbindingen bevatten.
DE68924545T2 (de) *	1988-02-23	1996-03-21	Merrell Dow Pharma	Verwendung von Chinolizin- und Chinolizinon-Derivaten zur Herstellung von Arzneimitteln.
US5140023A (en) *	1990-04-27	1992-08-18	G. D. Searle & Co.	Azatetracycle compounds
US5260303A (en)	1991-03-07	1993-11-09	G. D. Searle & Co.	Imidazopyridines as serotonergic 5-HT3 antagonists
US5280028A (en)	1992-06-24	1994-01-18	G. D. Searle & Co.	Benzimidazole compounds
US5521193A (en) *	1992-06-24	1996-05-28	G. D. Searle & Co.	Benzimidazole compounds
US5434151A (en)	1992-08-24	1995-07-18	Cytomed, Inc.	Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5840903A (en) *	1992-07-27	1998-11-24	G. D. Searle & Co.	4-aminomethyl-1-azaadamantane derived benzamides
US5399562A (en)	1994-02-04	1995-03-21	G. D. Searle & Co.	Indolones useful as serotonergic agents
WO1995021820A1 (fr) *	1994-02-10	1995-08-17	Yamanouchi Pharmaceutical Co., Ltd.	Nouveau derive du carbamate et composition correspondante
EP1125922A1 (de) *	1998-11-02	2001-08-22	Welfide Corporation	Pyrrolidin-verbindungen und eine medizinische anwendung dafür
MY145722A (en)	2000-04-27	2012-03-30	Abbott Lab	Diazabicyclic central nervous system active agents
JP4616971B2 (ja) *	2000-07-18	2011-01-19	田辺三菱製薬株式会社	１−アザビシクロアルカン化合物およびその医薬用途
CN101605784B (zh) *	2007-02-09	2013-04-10	安斯泰来制药株式会社	氮杂桥环化合物

2008
- 2008-03-20 MX MX2009010174A patent/MX2009010174A/es active IP Right Grant
- 2008-03-20 JP JP2009554736A patent/JP5566698B2/ja not_active Expired - Fee Related
- 2008-03-20 CN CN200880009459A patent/CN101641355A/zh active Pending
- 2008-03-20 EP EP08732552A patent/EP2129672B1/de active Active
- 2008-03-20 US US12/052,036 patent/US8163916B2/en not_active Expired - Fee Related
- 2008-03-20 CA CA002679870A patent/CA2679870A1/en not_active Abandoned
- 2008-03-20 ES ES08732552T patent/ES2363998T3/es active Active
- 2008-03-20 CN CN2013100426086A patent/CN103145711A/zh active Pending
- 2008-03-20 WO PCT/US2008/057641 patent/WO2008118742A1/en active Application Filing
- 2008-03-20 AT AT08732552T patent/ATE509931T1/de not_active IP Right Cessation
2010
- 2010-01-22 HK HK10100761.5A patent/HK1133642A1/xx not_active IP Right Cessation
2012
- 2012-03-23 US US13/427,999 patent/US20120190704A1/en not_active Abandoned
2014
- 2014-06-17 JP JP2014124038A patent/JP2014205695A/ja active Pending

Also Published As

Publication number	Publication date
US8163916B2 (en)	2012-04-24
CA2679870A1 (en)	2008-10-02
EP2129672B1 (de)	2011-05-18
ES2363998T3 (es)	2011-08-22
MX2009010174A (es)	2009-10-12
US20080255178A1 (en)	2008-10-16
EP2129672A4 (de)	2009-12-09
CN101641355A (zh)	2010-02-03
WO2008118742A1 (en)	2008-10-02
HK1133642A1 (en)	2010-04-01
CN103145711A (zh)	2013-06-12
JP2010522201A (ja)	2010-07-01
US20120190704A1 (en)	2012-07-26
JP2014205695A (ja)	2014-10-30
EP2129672A1 (de)	2009-12-09
JP5566698B2 (ja)	2014-08-06

Publication	Publication Date	Title
ATE509931T1 (de)	2011-06-15	Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafür
CY1118454T1 (el)	2017-07-12	Πρωτοτυποι αναστολεις πυρρολιου της αναγωγασης s-νιτροζογλουταθειονης ως θεραπευτικοι παραγοντες
MA32508B1 (fr)	2011-07-03	Composes organiques
CY1118143T1 (el)	2017-06-28	Ετεροκυκλικες ενωσεις χρησιμες ως αναστολεις της pdk1
EA201390609A1 (ru)	2014-01-30	ПРОИЗВОДНЫЕ ГИДАНТОИНА, ПОЛЕЗНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ Kv3-КАНАЛОВ
BRPI1015043A2 (pt)	2019-07-09	derivados de diazahomoadamantano e métodos de uso dos mesmos
NO20084334L (no)	2008-11-27	Farmasoytiske sammensetninger
NO20090596L (no)	2009-04-01	Antivirale fosfinatforbindelser
CY1112653T1 (el)	2016-02-10	Κρυσταλλικες τροποποιησεις της πυρακλοστροβινης
EA201270257A1 (ru)	2012-08-30	Производные n1-сульфонил-5-фторпиримидинона
PA8713501A1 (es)	2009-09-17	INHIBIDORES DE 11-BETA HIDROXIESTEROIDE DEHIDROGENASA - 11ßHSD1
NI201001033A (es)	2011-04-26	Formas cristalinas de dimetoxi docetaxel y metodo para preparar el mismo.
UA109123C2 (uk)	2015-07-27	Пробіотична композиція для застосування в лікуванні запалення кишечнику
SMP200900058B (it)	2010-11-12	Composti e composizioni come inibitori di proteinachinasi.
SM201000108A (it)	2011-01-19	Composti e composizioni come inibitori di proteinachinasi.
MA32369B1 (fr)	2011-06-01	Composes de benzene sulfonamide thiazole et oxazole
ECSP10010095A (es)	2010-07-30	2'-fluoro-2'-desoxitetrahidrouridinas como inhibidores de citidina desaminasa
EA201170832A1 (ru)	2011-12-30	Пуриновые соединения
EA201001639A1 (ru)	2011-06-30	Композиции и способы их получения и применения
EA201200323A1 (ru)	2012-09-28	Соединения и композиции, как ингибиторы протеинкиназы
CO6361894A2 (es)	2012-01-20	Composiciones aclaradoras de la piel con inhibidores de acetilcolinesterasa
UA106889C2 (uk)	2014-10-27	Похідні n1-ацил-5-фторпіримідинону
WO2009115084A3 (de)	2010-04-08	Pyrrolopyrimidin-derivate und deren verwendungen
EA201270256A1 (ru)	2012-07-30	Производные т1-замещенного 5-фтор-2-оксопиримидинон-1 (2h) -карбоксамида
MX2009010176A (es)	2009-10-12	Derivados de aza-adamantano 4-substituidos y metodos de uso de los mismos.

Legal Events

Date	Code	Title	Description
2011-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties