ATE432338T1 - Alanin-2,3-aminomutase - Google Patents
Alanin-2,3-aminomutaseInfo
- Publication number
- ATE432338T1 ATE432338T1 AT03707445T AT03707445T ATE432338T1 AT E432338 T1 ATE432338 T1 AT E432338T1 AT 03707445 T AT03707445 T AT 03707445T AT 03707445 T AT03707445 T AT 03707445T AT E432338 T1 ATE432338 T1 AT E432338T1
- Authority
- AT
- Austria
- Prior art keywords
- alanine
- aminomutase
- cells
- disclosed
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35072702P | 2002-01-18 | 2002-01-18 | |
US37578502P | 2002-04-25 | 2002-04-25 | |
PCT/US2003/001635 WO2003062173A2 (en) | 2002-01-18 | 2003-01-17 | Alanine 2,3- aminomutase |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE432338T1 true ATE432338T1 (de) | 2009-06-15 |
Family
ID=27616779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03707445T ATE432338T1 (de) | 2002-01-18 | 2003-01-17 | Alanin-2,3-aminomutase |
Country Status (10)
Country | Link |
---|---|
US (4) | US7309597B2 (de) |
EP (1) | EP1575881B1 (de) |
JP (1) | JP4532116B2 (de) |
AT (1) | ATE432338T1 (de) |
BR (1) | BR0307010A (de) |
CA (1) | CA2473716A1 (de) |
DE (1) | DE60327804D1 (de) |
ES (1) | ES2329778T3 (de) |
MX (1) | MXPA04006894A (de) |
WO (1) | WO2003062173A2 (de) |
Families Citing this family (80)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA04006894A (es) * | 2002-01-18 | 2004-10-15 | Cargill Inc | Alanina 2,3 - aminomutasa. |
WO2005118719A2 (en) | 2003-12-04 | 2005-12-15 | Cargill, Incorporated | Production of 3-hydroxypropionic acid using beta-alanine/pyruvate aminotransferase |
US20090031453A1 (en) * | 2004-07-30 | 2009-01-29 | Holly Jean Jessen | Alanine 2, 3 aminomutases |
US7790432B2 (en) * | 2004-10-25 | 2010-09-07 | Codexis, Inc. | Alanine 2,3-aminomutases and related polynucleotides |
DE102005048818A1 (de) * | 2005-10-10 | 2007-04-12 | Degussa Ag | Mikrobiologische Herstellung von 3-Hydroxypropionsäure |
US8030051B2 (en) | 2005-10-14 | 2011-10-04 | Codexis, Inc. | Alanine 2,3-aminomutases and related polynucleotides |
DK2011880T3 (da) | 2006-04-13 | 2012-11-26 | Chugai Pharmaceutical Co Ltd | Taurin transportergen |
DE102006039203B4 (de) | 2006-08-22 | 2014-06-18 | Evonik Degussa Gmbh | Verfahren zur Herstellung von durch Kristallisation gereinigter Acrylsäure aus Hydroxypropionsäure sowie Vorrichtung dazu |
CN101903513B (zh) * | 2007-01-12 | 2013-08-21 | 科罗拉多大学董事会法人 | 增强微生物对产生的有机化学物质的耐受性的组合物和方法 |
US8673601B2 (en) | 2007-01-22 | 2014-03-18 | Genomatica, Inc. | Methods and organisms for growth-coupled production of 3-hydroxypropionic acid |
WO2008114673A1 (ja) * | 2007-03-15 | 2008-09-25 | Chugai Seiyaku Kabushiki Kaisha | ポリペプチドの製造方法 |
CN101668861A (zh) * | 2007-03-16 | 2010-03-10 | 基因组股份公司 | 用于1,4-丁二醇和其前体生物合成的组合物和方法 |
DE102007015583A1 (de) | 2007-03-29 | 2008-10-02 | Albert-Ludwigs-Universität Freiburg | Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung |
KR101577839B1 (ko) | 2007-08-07 | 2015-12-15 | 추가이 세이야쿠 가부시키가이샤 | 이종 단백질의 제조 방법 |
US8026386B2 (en) | 2007-08-10 | 2011-09-27 | Genomatica, Inc. | Methods for the synthesis of olefins and derivatives |
US7947483B2 (en) * | 2007-08-10 | 2011-05-24 | Genomatica, Inc. | Methods and organisms for the growth-coupled production of 1,4-butanediol |
EP2194126B1 (de) | 2007-10-15 | 2014-01-15 | Chugai Seiyaku Kabushiki Kaisha | Verfahren zur konstruktion von zellen mit hoher produktivität von fremdprotein |
RU2494148C2 (ru) * | 2007-10-24 | 2013-09-27 | Чугаи Сейяку Кабусики Кайся | Клетка для получения гетеропротеинов и способ получения на ее основе |
US8048624B1 (en) | 2007-12-04 | 2011-11-01 | Opx Biotechnologies, Inc. | Compositions and methods for 3-hydroxypropionate bio-production from biomass |
BRPI0907385A2 (pt) * | 2008-01-22 | 2015-07-21 | Genomatica Inc | Métodos e organismos para utilização de gás de síntese e outras fontes de carbono gasosas e metanol |
JP5755884B2 (ja) | 2008-03-05 | 2015-07-29 | ジェノマティカ, インコーポレイテッド | 第一級アルコールを産生する生物 |
WO2009151728A2 (en) | 2008-03-27 | 2009-12-17 | Genomatica, Inc. | Microorganisms for the production of adipic acid and other compounds |
EP2285973A4 (de) | 2008-05-01 | 2012-04-25 | Genomatica Inc | Verfahren zur herstellung von methacrylsäure |
EP2304039B1 (de) | 2008-06-17 | 2019-08-21 | Genomatica, Inc. | Mikroorganismen und verfahren zur biosynthese von fumarat, malat und acrylat |
BRPI0918483A2 (pt) | 2008-09-10 | 2020-07-14 | Genomatica, Inc | organismo microbiano que não ocorre naturalmente, e, método para produzir um composto |
US20130189787A1 (en) * | 2008-09-15 | 2013-07-25 | Opx Biotechnologies ,Inc. | Methods, Systems And Compositions Related To Reduction Of Conversions Of Microbially Produced 3-Hydroxyproplonic Acid (3-HP) To Aldehyde Metabolites |
JP2012511928A (ja) | 2008-12-16 | 2012-05-31 | ゲノマチカ, インク. | 合成ガス及び他の炭素源の有用な製品への変換のための微生物及び方法 |
EP2210935A1 (de) * | 2009-01-19 | 2010-07-28 | Deinove | Verfahren zur Isolierung von Bakterien |
US20120149077A1 (en) * | 2009-03-13 | 2012-06-14 | Mascoma Corporation | Mesophilic and Thermophilic Organisms Modified to Produce Acrylate, and Methods of Use Thereof |
JP5715050B2 (ja) | 2009-04-22 | 2015-05-07 | 中外製薬株式会社 | 異種タンパク質を高生産する細胞の作製方法 |
EP3318626B1 (de) | 2009-04-30 | 2020-01-15 | Genomatica, Inc. | Organismen zur herstellung von 1,3-butandiol |
BRPI1013505A2 (pt) | 2009-04-30 | 2018-02-14 | Genomatica Inc | organismos para a produção de isopropanol, n-butanol, e isobutanol |
EP2427544B1 (de) | 2009-05-07 | 2019-07-17 | Genomatica, Inc. | Mikrooganismen und verfahren für die biosynthese von adipat, hexamethylendiamin und 6-aminocapronsäure |
WO2010132845A1 (en) | 2009-05-15 | 2010-11-18 | Genomatica, Inc. | Organisms for the production of cyclohexanone |
BRPI1010581A2 (pt) | 2009-06-04 | 2016-11-08 | Genomatica Inc | micro-organismos para a produção de 1,4-butanodiol e métodos relacionados |
KR102176554B1 (ko) | 2009-06-04 | 2020-11-09 | 게노마티카 인코포레이티드 | 발효액 성분들의 분리 방법 |
JP2012529889A (ja) | 2009-06-10 | 2012-11-29 | ゲノマチカ, インク. | Mek及び2−ブタノールの炭素効率のよい生合成のための微生物及び方法 |
US20120160686A1 (en) | 2009-07-01 | 2012-06-28 | Novozymes North America, Inc. | Process for separating and recovering 3-hydroxypropionic acid |
WO2011017560A1 (en) | 2009-08-05 | 2011-02-10 | Genomatica, Inc. | Semi-synthetic terephthalic acid via microorganisms that produce muconic acid |
CA2773694A1 (en) | 2009-09-09 | 2011-03-17 | Genomatica, Inc. | Microorganisms and methods for the co-production of isopropanol with primary alcohols, diols and acids |
US8809027B1 (en) | 2009-09-27 | 2014-08-19 | Opx Biotechnologies, Inc. | Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase |
MX2012003604A (es) | 2009-09-27 | 2012-09-12 | Opx Biotechnologies Inc | Metodo para producir acido 3-hidroxipropionico y otros productos. |
MX2012004291A (es) | 2009-10-13 | 2012-08-17 | Genomatica Inc | Microorganismos para la produccion de 1,4-butanoidol, 4-hidroxibutanal, 4-hidroxibutiril-coa, putrescina y compuestos y metodos relacionados con los mismos. |
EP2491125A4 (de) | 2009-10-23 | 2014-04-23 | Genomatica Inc | Mikroorganismen zur herstellung von anilin |
US20110125118A1 (en) * | 2009-11-20 | 2011-05-26 | Opx Biotechnologies, Inc. | Production of an Organic Acid and/or Related Chemicals |
WO2011066076A1 (en) | 2009-11-25 | 2011-06-03 | Genomatica, Inc. | Microorganisms and methods for the coproduction of 1,4-butanediol and gamma-butyrolactone |
CN102753698A (zh) | 2009-12-10 | 2012-10-24 | 基因组股份公司 | 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体 |
WO2011081658A2 (en) * | 2009-12-15 | 2011-07-07 | Qteros, Inc. | Methods and compositions for producing chemical products from c. phytofermentants |
CN102834508A (zh) | 2010-01-29 | 2012-12-19 | 基因组股份公司 | 用于生物合成对甲苯甲酸和对苯二甲酸的微生物和方法 |
US9410131B2 (en) | 2010-02-11 | 2016-08-09 | Yeda Research And Development Co. Ltd. | Enzymatic systems for carbon fixation and methods of generating same |
US8445244B2 (en) | 2010-02-23 | 2013-05-21 | Genomatica, Inc. | Methods for increasing product yields |
US8048661B2 (en) | 2010-02-23 | 2011-11-01 | Genomatica, Inc. | Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes |
US9023636B2 (en) | 2010-04-30 | 2015-05-05 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of propylene |
SG185432A1 (en) | 2010-05-05 | 2012-12-28 | Genomatica Inc | Microorganisms and methods for the biosynthesis of butadiene |
EP2588598B1 (de) | 2010-07-02 | 2016-03-09 | Metabolic Explorer | Verfahren zur herstellung von hydroxysäuren |
US8715957B2 (en) | 2010-07-26 | 2014-05-06 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene |
US9090918B2 (en) | 2010-11-22 | 2015-07-28 | Novozymes A/A | Compositions and methods for 3-hydroxypropionic acid production |
US8765426B2 (en) | 2011-04-07 | 2014-07-01 | E I Du Pont De Nemours And Company | Pantothenic acid biosynthesis in zymomonas |
US9169486B2 (en) | 2011-06-22 | 2015-10-27 | Genomatica, Inc. | Microorganisms for producing butadiene and methods related thereto |
JP2014528726A (ja) | 2011-09-30 | 2014-10-30 | ノボザイムス,インコーポレイティド | デヒドロゲナーゼ変異体およびこれをコードするポリヌクレオチド |
EP2855687B1 (de) | 2012-06-04 | 2020-04-22 | Genomatica, Inc. | Mikroorganismen und verfahren zur herstellung von 4-hydroxybutyrat, 1,4-butandiol und verwandten verbindungen |
SG11201501013PA (en) | 2012-08-10 | 2015-04-29 | Opx Biotechnologies Inc | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
CA2891130A1 (en) | 2012-11-30 | 2014-06-05 | Novozymes, Inc. | 3-hydroxypropionic acid production by recombinant yeasts |
NZ743055A (en) | 2013-03-08 | 2020-03-27 | Xyleco Inc | Equipment protecting enclosures |
BR112015023583A2 (pt) | 2013-03-15 | 2017-08-22 | Dow Global Technologies Llc | Método para vaporização 3-hp a partir de uma solução, vapor, solução 3-hp condensada, composição, produto químico à jusante, produto de consumo, sistema para purificação de 3-hp, método para produzir uma solução de 3-hp, método para decompor a amônia de 3-hp (a3-hp) e método para decompor a3-hp |
WO2014146026A1 (en) | 2013-03-15 | 2014-09-18 | Opx Biotechnologies, Inc. | Bioproduction of chemicals |
CN108358755B (zh) | 2013-03-15 | 2021-08-10 | 基因组股份公司 | 用于从发酵肉汤中获得1,4-丁二醇的方法和系统 |
EP2970085B1 (de) | 2013-03-15 | 2018-11-07 | Cargill, Incorporated | Rückgewinnung von 3-hydroxypropionsäure |
WO2014176514A2 (en) | 2013-04-26 | 2014-10-30 | Genomatica, Inc. | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds |
WO2014190251A1 (en) | 2013-05-24 | 2014-11-27 | Genomatica, Inc. | Microorganisms and methods for producing (3r)-hydroxybutyl (3r)-hydroxybutyrate |
US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
BR112016001026A2 (pt) | 2013-07-19 | 2017-10-24 | Cargill Inc | organismo geneticamente modificado |
DK3027733T3 (en) | 2013-07-31 | 2018-12-10 | Novozymes As | Preparation of 3-Hydroxypropionic Acid in Recombinant Yeast Expressing an Insect Aspartate-1 Decarboxylase |
DE112015003962T5 (de) | 2014-08-29 | 2017-08-03 | Sk Innovation Co., Ltd. | 3-Hydroxypropionsäure erzeugende rekombinante Hefe und Verfahren zum Herstellen von 3-Hydroxypropionsäure unter Nutzung derselben |
EP2993228B1 (de) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Herstellung von fettsäureestern |
KR101839595B1 (ko) * | 2015-04-13 | 2018-04-26 | 한국과학기술원 | 락탐의 제조방법 |
US20180265902A1 (en) | 2015-08-24 | 2018-09-20 | Novozymes A/S | Beta-Alanine Aminotransferases For The Production of 3-Hydroxypropionic Acid |
KR101828551B1 (ko) * | 2016-01-11 | 2018-02-13 | 한국과학기술원 | 말론산 생성능을 가지는 재조합 변이미생물 및 이를 이용한 말론산의 제조방법 |
DE102016114555A1 (de) | 2016-08-05 | 2018-02-08 | Thyssenkrupp Ag | Prozess zur Herstellung von Acrylsäure aus einer wässrigen 3-Hydroxypropanol-Lösung |
CN110494566A (zh) | 2017-02-02 | 2019-11-22 | 嘉吉公司 | 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5643758A (en) * | 1987-03-10 | 1997-07-01 | New England Biolabs, Inc. | Production and purification of a protein fused to a binding protein |
ATE452979T1 (de) * | 1996-11-13 | 2010-01-15 | Du Pont | Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen |
US6248874B1 (en) | 1998-11-24 | 2001-06-19 | Wisconsin Alumni Research Foundation | DNA molecules encoding bacterial lysine 2,3-aminomutase |
US7452701B2 (en) | 1998-11-24 | 2008-11-18 | Wisconsin Alumni Research Foundation | Methods for the preparation of β-amino acids |
DE19855314A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentiven Herstellung von D-Pantothensäure unter Verwendung von Stämmen der Familie Enterobacteriaceae |
DE19855312A1 (de) | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien |
AU7093600A (en) | 1999-08-30 | 2001-03-26 | Wisconsin Alumni Research Foundation | Production of 3-hydroxypropionic acid in recombinant organisms |
EP1214420B1 (de) * | 1999-09-21 | 2016-03-23 | Basf Se | Verfahren und mikroorganismen zur produktion von panto-verbindungen |
PT1218494E (pt) | 1999-09-22 | 2005-08-31 | Canbas Co Ltd | Composicoes e metodos para inibir a paragem do ciclo celular g2 e para sensibilizar celulas perante agentes que danificam o adn |
AU2002219818B2 (en) | 2000-11-20 | 2007-08-16 | Cargill, Incorporated | 3-hydroxypropionic acid and other organic compounds |
MXPA04006894A (es) * | 2002-01-18 | 2004-10-15 | Cargill Inc | Alanina 2,3 - aminomutasa. |
WO2005118719A2 (en) * | 2003-12-04 | 2005-12-15 | Cargill, Incorporated | Production of 3-hydroxypropionic acid using beta-alanine/pyruvate aminotransferase |
US20090031453A1 (en) | 2004-07-30 | 2009-01-29 | Holly Jean Jessen | Alanine 2, 3 aminomutases |
US7790432B2 (en) | 2004-10-25 | 2010-09-07 | Codexis, Inc. | Alanine 2,3-aminomutases and related polynucleotides |
WO2007047680A2 (en) | 2005-10-14 | 2007-04-26 | Cargill, Incorporated | Increasing the activity of radical s-adenosyl methionine (sam) enzymes |
US8030051B2 (en) | 2005-10-14 | 2011-10-04 | Codexis, Inc. | Alanine 2,3-aminomutases and related polynucleotides |
-
2003
- 2003-01-17 MX MXPA04006894A patent/MXPA04006894A/es unknown
- 2003-01-17 ES ES03707445T patent/ES2329778T3/es not_active Expired - Lifetime
- 2003-01-17 CA CA002473716A patent/CA2473716A1/en not_active Abandoned
- 2003-01-17 US US10/502,040 patent/US7309597B2/en not_active Expired - Fee Related
- 2003-01-17 DE DE60327804T patent/DE60327804D1/de not_active Expired - Lifetime
- 2003-01-17 EP EP03707445A patent/EP1575881B1/de not_active Expired - Lifetime
- 2003-01-17 WO PCT/US2003/001635 patent/WO2003062173A2/en active Search and Examination
- 2003-01-17 JP JP2003562058A patent/JP4532116B2/ja not_active Expired - Fee Related
- 2003-01-17 BR BRPI0307010-7A patent/BR0307010A/pt not_active Application Discontinuation
- 2003-01-17 AT AT03707445T patent/ATE432338T1/de not_active IP Right Cessation
-
2007
- 2007-11-09 US US11/938,154 patent/US7655451B2/en not_active Expired - Fee Related
-
2009
- 2009-12-21 US US12/643,136 patent/US7846707B2/en not_active Expired - Fee Related
-
2010
- 2010-11-04 US US12/939,405 patent/US8043841B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20080124785A1 (en) | 2008-05-29 |
ES2329778T3 (es) | 2009-12-01 |
US20050221466A1 (en) | 2005-10-06 |
US20110045573A1 (en) | 2011-02-24 |
EP1575881A2 (de) | 2005-09-21 |
DE60327804D1 (de) | 2009-07-09 |
JP4532116B2 (ja) | 2010-08-25 |
EP1575881B1 (de) | 2009-05-27 |
CA2473716A1 (en) | 2003-07-31 |
US20100099167A1 (en) | 2010-04-22 |
BR0307010A (pt) | 2006-04-11 |
MXPA04006894A (es) | 2004-10-15 |
WO2003062173A3 (en) | 2005-08-04 |
WO2003062173A8 (en) | 2005-11-03 |
US7846707B2 (en) | 2010-12-07 |
US7655451B2 (en) | 2010-02-02 |
EP1575881A4 (de) | 2006-02-01 |
JP2005525100A (ja) | 2005-08-25 |
WO2003062173A2 (en) | 2003-07-31 |
US8043841B2 (en) | 2011-10-25 |
US7309597B2 (en) | 2007-12-18 |
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