ATE403659T1 - Camptothecine mit modifiziertem lactonring - Google Patents

Camptothecine mit modifiziertem lactonring

Info

Publication number: ATE403659T1
Authority: AT; Austria
Prior art keywords: camptothecine; lactone ring; modified lactone; modified; ring
Prior art date: 2002-05-31

Application number

AT06116366T

Other languages

English (en)

Inventor

Mauro Marzi

Elena Marastoni

Sergio Penco

Claudio Pisano

Maria Ornella Tinti

Loredana Vesci

Franco Zunino

Domenico Vergani

Walter Cabri

Marco Alpegiani

Martin Patricio

Tamara Danelli

Original Assignee

Sigma Tau Ind Farmaceuti

Ist Naz Stud Cura Dei Tumori

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-31

Filing date

2003-05-28

Publication date

2008-08-15

2003-05-28 Application filed by Sigma Tau Ind Farmaceuti, Ist Naz Stud Cura Dei Tumori filed Critical Sigma Tau Ind Farmaceuti

2008-08-15 Application granted granted Critical

2008-08-15 Publication of ATE403659T1 publication Critical patent/ATE403659T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Epoxy Compounds (AREA)

AT06116366T 2002-05-31 2003-05-28 Camptothecine mit modifiziertem lactonring ATE403659T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT2002RM000305A ITRM20020305A1 (it)	2002-05-31	2002-05-31	Camptotecine con anello lattonico modificato.

Publications (1)

Publication Number	Publication Date
ATE403659T1 true ATE403659T1 (de)	2008-08-15

Family

ID=11456338

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT06116366T ATE403659T1 (de)	2002-05-31	2003-05-28	Camptothecine mit modifiziertem lactonring
AT03730480T ATE339422T1 (de)	2002-05-31	2003-05-28	Camptothecine mit modifiziertem lactonring

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT03730480T ATE339422T1 (de)	2002-05-31	2003-05-28	Camptothecine mit modifiziertem lactonring

Country Status (22)

Country	Link
US (1)	US7273873B2 (de)
EP (2)	EP1511752B3 (de)
JP (1)	JP4693410B2 (de)
KR (1)	KR101042042B1 (de)
CN (1)	CN1656100A (de)
AR (1)	AR040139A1 (de)
AT (2)	ATE403659T1 (de)
AU (2)	AU2003241160B2 (de)
BR (2)	BR0311329A (de)
CA (2)	CA2706635A1 (de)
CY (2)	CY1107311T1 (de)
DE (2)	DE60322754D1 (de)
DK (2)	DK1719775T3 (de)
ES (2)	ES2312090T3 (de)
IT (1)	ITRM20020305A1 (de)
MX (1)	MXPA04011682A (de)
PE (1)	PE20050120A1 (de)
PL (1)	PL374346A1 (de)
PT (2)	PT1719775E (de)
SI (2)	SI1719775T1 (de)
TW (1)	TWI325866B (de)
WO (1)	WO2003101995A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2852606A1 (fr) *	2003-03-18	2004-09-24	Inst Nat Sante Rech Med	Moyens pour inhiber simultanement l'expression de plusieurs genes impliques dans une pathologie
ITRM20030344A1 (it)	2003-07-14	2005-01-15	Ist Naz Stud Cura Dei Tumori	7-n-poliamminoalchil(ossi)imminometilcamptotecine recanti gruppi protettivi.
WO2009016068A1 (en) *	2007-08-01	2009-02-05	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Crystalline form ii of 7-(dimethoxy-methyl) camptothecin, its use as intermediate and products obtained therefrom
CN102746314B (zh) *	2011-04-18	2016-07-06	华东师范大学	含有稳定7元内酯环的喜树碱类化合物、制备方法和用途
CN104530066A (zh) *	2015-01-06	2015-04-22	华东师范大学	一类新型高喜树碱衍生物、制备方法和用途
US11826430B2 (en)	2019-05-14	2023-11-28	Nuvation Bio Inc.	Anti-cancer nuclear hormone receptor-targeting compounds
US11952349B2 (en)	2019-11-13	2024-04-09	Nuvation Bio Inc.	Anti-cancer nuclear hormone receptor-targeting compounds
CN117295747A (zh)	2021-03-23	2023-12-26	诺维逊生物股份有限公司	抗癌核激素受体靶向化合物
IL308104A (en)	2021-05-03	2023-12-01	Nuvation Bio Inc	Nuclear hormone receptor-targeted compounds against cancer
WO2024073626A2 (en) *	2022-09-28	2024-04-04	Nuvation Bio Inc.	Anti-cancer nuclear hormone receptor-targeting compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4399276A (en) *	1981-01-09	1983-08-16	Kabushiki Kaisha Yakult Honsha	7-Substituted camptothecin derivatives
JPS57116076A (en) *	1981-01-09	1982-07-19	Yakult Honsha Co Ltd	Novel camptothecin derivative and its preparation
FR2532591A1 (fr)	1982-09-02	1984-03-09	Hutchinson	Nouveau dispositif de securite pour pneumatiques de vehicules ou autres engins
DE69623961T2 (de) *	1995-06-21	2003-05-08	Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.), Paris	Camptothecinanaloge, verfahren zur ihrer herstellung, ihre verwendungals arzneimittel und diese enthaltende pharmazeutische zusammenfassungen
EP1044977B1 (de) *	1999-03-09	2002-05-02	Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.	Camptothecin-Derivate mit Antitumor-Wirkung

2002
- 2002-05-31 IT IT2002RM000305A patent/ITRM20020305A1/it unknown
2003
- 2003-05-26 TW TW092114164A patent/TWI325866B/zh not_active IP Right Cessation
- 2003-05-28 ES ES06116366T patent/ES2312090T3/es not_active Expired - Lifetime
- 2003-05-28 EP EP03730480A patent/EP1511752B3/de not_active Expired - Lifetime
- 2003-05-28 CA CA2706635A patent/CA2706635A1/en not_active Abandoned
- 2003-05-28 CN CNA038125439A patent/CN1656100A/zh active Pending
- 2003-05-28 CA CA2485201A patent/CA2485201C/en not_active Expired - Fee Related
- 2003-05-28 MX MXPA04011682A patent/MXPA04011682A/es active IP Right Grant
- 2003-05-28 BR BR0311329-9A patent/BR0311329A/pt not_active IP Right Cessation
- 2003-05-28 SI SI200331380T patent/SI1719775T1/sl unknown
- 2003-05-28 AT AT06116366T patent/ATE403659T1/de active
- 2003-05-28 SI SI200330509T patent/SI1511752T1/sl unknown
- 2003-05-28 KR KR1020047016880A patent/KR101042042B1/ko not_active IP Right Cessation
- 2003-05-28 US US10/511,724 patent/US7273873B2/en not_active Expired - Fee Related
- 2003-05-28 AU AU2003241160A patent/AU2003241160B2/en not_active Ceased
- 2003-05-28 EP EP06116366A patent/EP1719775B1/de not_active Expired - Lifetime
- 2003-05-28 BR BR0311333-7A patent/BR0311333A/pt not_active IP Right Cessation
- 2003-05-28 DE DE60322754T patent/DE60322754D1/de not_active Expired - Lifetime
- 2003-05-28 PT PT06116366T patent/PT1719775E/pt unknown
- 2003-05-28 AT AT03730480T patent/ATE339422T1/de active
- 2003-05-28 ES ES03730480T patent/ES2273002T7/es active Active
- 2003-05-28 DK DK06116366T patent/DK1719775T3/da active
- 2003-05-28 JP JP2004509686A patent/JP4693410B2/ja not_active Expired - Fee Related
- 2003-05-28 DE DE60308368T patent/DE60308368T3/de not_active Expired - Lifetime
- 2003-05-28 WO PCT/IT2003/000328 patent/WO2003101995A2/en active IP Right Grant
- 2003-05-28 PL PL03374346A patent/PL374346A1/xx unknown
- 2003-05-28 PT PT03730480T patent/PT1511752E/pt unknown
- 2003-05-28 DK DK03730480.5T patent/DK1511752T5/da active
- 2003-05-30 PE PE2003000529A patent/PE20050120A1/es not_active Application Discontinuation
- 2003-05-30 AR ARP030101915A patent/AR040139A1/es unknown
2006
- 2006-11-14 CY CY20061101648T patent/CY1107311T1/el unknown
2008
- 2008-10-31 CY CY20081101240T patent/CY1108793T1/el unknown
2009
- 2009-11-12 AU AU2009236044A patent/AU2009236044B8/en not_active Ceased

Also Published As

Publication number	Publication date
CA2485201A1 (en)	2003-12-11
AR040139A1 (es)	2005-03-16
DE60308368D1 (de)	2006-10-26
DK1511752T5 (da)	2010-06-14
JP4693410B2 (ja)	2011-06-01
ES2312090T3 (es)	2009-02-16
EP1719775A1 (de)	2006-11-08
ITRM20020305A0 (it)	2002-05-31
US7273873B2 (en)	2007-09-25
BR0311333A (pt)	2005-03-15
BR0311329A (pt)	2005-02-22
AU2009236044B8 (en)	2011-07-21
CY1107311T1 (el)	2012-11-21
CA2706635A1 (en)	2003-12-11
EP1511752A2 (de)	2005-03-09
EP1511752B1 (de)	2006-09-13
US20050154003A1 (en)	2005-07-14
PT1511752E (pt)	2007-01-31
EP1511752B8 (de)	2007-04-18
SI1719775T1 (sl)	2009-04-30
SI1511752T1 (sl)	2007-02-28
CY1108793T1 (el)	2014-04-09
JP2005531602A (ja)	2005-10-20
AU2003241160A1 (en)	2003-12-19
DE60322754D1 (de)	2008-09-18
DE60308368T2 (de)	2007-09-06
DK1719775T3 (da)	2008-11-17
AU2009236044B2 (en)	2011-03-24
CN1656100A (zh)	2005-08-17
DE60308368T3 (de)	2010-09-16
MXPA04011682A (es)	2005-03-31
AU2009236044A8 (en)	2011-07-21
KR20050036909A (ko)	2005-04-20
AU2003241160B2 (en)	2009-08-20
TW200404806A (en)	2004-04-01
TWI325866B (en)	2010-06-11
ES2273002T3 (es)	2007-05-01
ITRM20020305A1 (it)	2003-12-01
WO2003101995A2 (en)	2003-12-11
ATE339422T1 (de)	2006-10-15
PE20050120A1 (es)	2005-03-04
CA2485201C (en)	2010-11-02
DK1511752T3 (da)	2007-01-29
AU2009236044A1 (en)	2009-12-03
EP1719775B1 (de)	2008-08-06
PT1719775E (pt)	2008-09-30
WO2003101995A3 (en)	2004-02-19
KR101042042B1 (ko)	2011-06-16
EP1511752B3 (de)	2010-03-10
PL374346A1 (en)	2005-10-17
WO2003101995A8 (en)	2004-12-23
ES2273002T7 (es)	2011-08-01

Publication	Publication Date	Title
IS7662A (is)	2005-01-24	Ný þríhringlaga spírópíperídín eða spírópýrrólídín
DE60326055D1 (de)	2009-03-19	Ölring
DE60302321D1 (de)	2005-12-22	Zusammengesetzter Ölring
DE03726967T1 (de)	2005-05-04	Wirbelringerzeuger
FR2837895B1 (fr)	2007-02-09	Segment de piston
DE60334181D1 (de)	2010-10-28	Radsupport mit Lageranordnung
ATE453811T1 (de)	2010-01-15	Synchronring
DK1489078T3 (da)	2010-03-15	Benzofuranderivat
ATE428695T1 (de)	2009-05-15	Spirocyclische 3-phenyl-3-substituierte-4- ketolaktame und -laktone
DE60308836D1 (de)	2006-11-16	Ophthalmische zubereitung mit ascomycin
DE60332705D1 (de)	2010-07-08	Kolbenring mit spritzbeschichtung
ATE339422T1 (de)	2006-10-15	Camptothecine mit modifiziertem lactonring
DE60206313D1 (de)	2006-02-09	Zentrifuge mit Sensor
DE60239391D1 (de)	2011-04-21	rgungsringes mit großem parasitärem Widerstand
DE60311138D1 (de)	2007-02-22	Pll mit symmetrischem quadrikorrelator
FR2838029B1 (fr)	2005-12-30	Bague
DE60306439D1 (de)	2006-08-10	Komparator mit Hysterese
FR2848277B1 (fr)	2008-04-25	Segment de piston
ATA16062002A (de)	2003-07-15	Schlüsselanhänger
DE50102733D1 (de)	2004-08-05	Synchronring
ES1053752Y (es)	2003-08-16	Anillo.
FI20031897A0 (fi)	2003-12-23	Rengas
ES1056347Y (es)	2004-07-01	Alzador de faldas.
ES1052155Y (es)	2003-03-16	Baliza luminosa.
ITTO20020290A1 (it)	2003-10-02	Anello

Legal Events

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2009-04-15	UEP	Publication of translation of european patent specification	Ref document number: 1719775 Country of ref document: EP

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