ATE495187T1 - Dalda-analoge und ihre verwendung - Google Patents

Dalda-analoge und ihre verwendung

Info

Publication number: ATE495187T1
Authority: AT; Austria
Prior art keywords: dalda; analogues; management; pain; compounds
Prior art date: 1999-03-16

Application number

AT00917550T

Other languages

English (en)

Inventor

Peter Schiller

Szeto Hazel

Original Assignee

Cornell Res Foundation Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-16

Filing date

2000-03-08

Publication date

2011-01-15

2000-03-08 Application filed by Cornell Res Foundation Inc filed Critical Cornell Res Foundation Inc

2011-01-15 Application granted granted Critical

2011-01-15 Publication of ATE495187T1 publication Critical patent/ATE495187T1/de

Links

UEVAHGMTRWGMTB-JBXUNAHCSA-N (2s)-6-amino-2-[[(2s)-2-[[(2r)-2-[[(2s)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]hexanamide Chemical class C([C@@H](C(=O)N[C@@H](CCCCN)C(N)=O)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=CC=C1 UEVAHGMTRWGMTB-JBXUNAHCSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
General Chemical & Material Sciences (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Treating Waste Gases (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT00917550T 1999-03-16 2000-03-08 Dalda-analoge und ihre verwendung ATE495187T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9900961A SE9900961D0 (sv)	1999-03-16	1999-03-16	Novel compounds
PCT/SE2000/000462 WO2000055189A1 (en)	1999-03-16	2000-03-08	Dalda analogs and their use

Publications (1)

Publication Number	Publication Date
ATE495187T1 true ATE495187T1 (de)	2011-01-15

Family

ID=20414882

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00917550T ATE495187T1 (de)	1999-03-16	2000-03-08	Dalda-analoge und ihre verwendung

Country Status (8)

Country	Link
US (2)	US6703483B1 (de)
EP (1)	EP1163263B1 (de)
AT (1)	ATE495187T1 (de)
AU (1)	AU3850600A (de)
CA (1)	CA2361364C (de)
DE (1)	DE60045508D1 (de)
SE (1)	SE9900961D0 (de)
WO (1)	WO2000055189A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6541021B1 (en) *	1999-03-18	2003-04-01	Durect Corporation	Devices and methods for pain management
US7074803B2 (en) *	2001-03-02	2006-07-11	Durect Corporation	Opioid formulations
WO2002005748A2 (en)	2000-07-18	2002-01-24	Cornell Research Foundation, Inc.	Medicinal uses of mu-opioid receptor agonists
US20040102476A1 (en) *	2002-11-25	2004-05-27	Chan Tai Wah	High concentration formulations of opioids and opioid derivatives
CN102784383B (zh) *	2003-02-04	2014-09-17	科内尔研究基金会	用于防止线粒体通透性改变的方法
KR101161823B1 (ko) *	2003-05-01	2012-07-03	코넬 리서치 화운데이션,인크.	세포로 분자를 전달하는 방법 및 이것을 위한 캐리어 복합체
CA2971931C (en)	2004-01-23	2019-01-08	Cornell Research Foundation, Inc.	Methods for reducing oxidative damage
US20050282756A1 (en) *	2004-06-18	2005-12-22	Mehta Nozer M	Oral delivery of peptide pharmaceutical compositions
KR20140106761A (ko) *	2005-09-16	2014-09-03	코넬 리서치 화운데이션,인크.	Ｃｄ36 발현을 감소시키는 방법
US8093207B2 (en) *	2005-12-09	2012-01-10	Unigene Laboratories, Inc.	Fast-acting oral peptide pharmaceutical products
EP3441079A1 (de)	2008-02-07	2019-02-13	Cornell University	Verfahren zur vorbeugung oder behandlung von insulinresistenz
EP2262520B1 (de)	2008-02-26	2017-05-03	Cornell University	Zusammensetzungen zur prävention und behandlung von nierenschädigung
EP3563862B1 (de)	2009-03-20	2021-05-05	The General Hospital Corporation d/b/a Massachusetts General Hospital	D-arg-2'6'-dimethyltyrosin-lys-phe-nh2 zur verhinderung von sekundären komplikationen von brandverletzungen
CN107412724A (zh) *	2009-08-12	2017-12-01	康奈尔大学	预防或治疗代谢综合症的方法
CN102625709A (zh)	2009-08-24	2012-08-01	康肽德生物医药技术有限公司	用于预防或治疗眼科病症的方法和组合物
US20110082084A1 (en) *	2009-10-05	2011-04-07	Szeto Hazel H	Methods for the prevention or treatment of heart failure
EP3375449A1 (de) *	2010-03-15	2018-09-19	Stealth Peptides International, Inc.	Kombinationstherapien mit cyclosporin und aromatischen kationischen peptiden
US20110245182A1 (en)	2010-04-06	2011-10-06	Perricone Nicholas V	Topical Uses of Szeto-Schiller Peptides
US20110245183A1 (en)	2010-04-06	2011-10-06	Perricone Nicholas V	Topical Uses of Szeto-Schiller Peptides
US20120083452A1 (en)	2010-09-30	2012-04-05	Perricone Nicholas V	Topical Anesthetic Uses of Szeto-Schiller Peptides
JP2017523956A (ja)	2014-06-25	2017-08-24	フラマソシエタペルアチオニＦｌａｍｍａＳ．Ｐ．Ａ．	Ｄ−アルギニル−２，６−ジメチル−ｌ−チロシル−ｌ−リシル−ｌ−フェニルアラニンアミドの調製方法
PL3160985T3 (pl)	2014-06-30	2021-12-27	Flamma S.P.A.	Sposób wytwarzania d-arginylo-2,6-dimetylo-l-tyrozylo-l-lizylo-l-fenyloalaninoamidu
CA2978905A1 (en) *	2015-03-06	2016-09-15	Stealth Biotherapeutics Corp	Processes for preparing pharmaceutically relevant peptides
WO2018187400A1 (en)	2017-04-05	2018-10-11	Stealth Biotherapeutics Corp.	Crystalline salt forms of boc-d-arg-dmt-lys-(boc)-phe-nh2
US10676506B2 (en)	2018-01-26	2020-06-09	Stealth Biotherapeutics Corp.	Crystalline bis- and tris-hydrochloride salt of elamipretide
KR102666922B1 (ko)	2020-09-09	2024-05-20	소셜 프로핏 네트워크	미토콘드리아에 비오틴의 전달을 위한 방법 및 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5312899A (en) *	1988-06-30	1994-05-17	Biochem Pharma, Inc.	Dermorphin analogs
US5602100A (en) *	1988-06-30	1997-02-11	Astra Ab	Dermorphin analogs having pharmacological activity
IS4261A (is)	1994-02-21	1995-08-22	Astra Aktiebolag	Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra
US5849761A (en) *	1995-09-12	1998-12-15	Regents Of The University Of California	Peripherally active anti-hyperalgesic opiates
US5788307A (en) *	1996-08-23	1998-08-04	Gilbert; Louis A.	Pickup body protection apparatus
US5885958A (en) *	1997-03-25	1999-03-23	Administrators Of The Tulane Educational Fund	Mu-opiate receptor peptides

1999
- 1999-03-16 SE SE9900961A patent/SE9900961D0/xx unknown
2000
- 2000-03-08 CA CA2361364A patent/CA2361364C/en not_active Expired - Lifetime
- 2000-03-08 AU AU38506/00A patent/AU3850600A/en not_active Abandoned
- 2000-03-08 WO PCT/SE2000/000462 patent/WO2000055189A1/en active Application Filing
- 2000-03-08 AT AT00917550T patent/ATE495187T1/de not_active IP Right Cessation
- 2000-03-08 EP EP00917550A patent/EP1163263B1/de not_active Expired - Lifetime
- 2000-03-08 US US09/590,165 patent/US6703483B1/en not_active Expired - Lifetime
- 2000-03-08 DE DE60045508T patent/DE60045508D1/de not_active Expired - Lifetime
2004
- 2004-02-25 US US10/785,155 patent/US20040176305A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1163263B1 (de)	2011-01-12
SE9900961D0 (sv)	1999-03-16
CA2361364A1 (en)	2000-09-21
US20040176305A1 (en)	2004-09-09
AU3850600A (en)	2000-10-04
CA2361364C (en)	2011-02-15
DE60045508D1 (de)	2011-02-24
EP1163263A1 (de)	2001-12-19
US6703483B1 (en)	2004-03-09
WO2000055189A1 (en)	2000-09-21

Publication	Publication Date	Title
ATE495187T1 (de)	2011-01-15	Dalda-analoge und ihre verwendung
SE9504661D0 (sv)	1995-12-22	New compounds
SE0101387D0 (sv)	2001-04-20	Novel compounds
WO2004060882A8 (en)	2005-03-24	Cb 1/cb 2 receptor ligands and their use in the treatment of pain
NO20065904L (no)	2007-02-20	Terapeutiske forbindelser
SE0401345D0 (sv)	2004-05-25	Therapeutic compounds: Pyridine as scaffold
SE9802208D0 (sv)	1998-06-22	Novel compounds
SE0402762D0 (sv)	2004-11-11	Indazole sulphonamide derivatives
SE0104250D0 (sv)	2001-12-14	Heterocyclic compounds
SE9802206D0 (sv)	1998-06-22	Novel compounds
SE0302573D0 (sv)	2003-09-26	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
PE20030061A1 (es)	2003-02-08	1-biaril-1,8-naftiridin-4-ona como inhibidores de fosfodiesterasa-4
SE0300908D0 (sv)	2003-03-31	Azaindole derivatives, preparations thereof, uses thereof and compositions containing them
TW200504029A (en)	2005-02-01	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0203070D0 (en)	2002-10-16	Novel compounds
SE0203303D0 (sv)	2002-11-07	Novel Compounds
TW200504030A (en)	2005-02-01	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302570D0 (sv)	2003-09-26	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0203300D0 (sv)	2002-11-07	Novel Compounds
SE9802209D0 (sv)	1998-06-22	Novel compounds
SE0302572D0 (sv)	2003-09-26	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0300105D0 (sv)	2003-01-16	Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof
SE9504662D0 (sv)	1995-12-22	New compounds
UY27587A1 (es)	2003-07-31	Heterociclos terapéuticos
ES2192789T3 (es)	2003-10-16	Derivados de hidrazono-benzazuleno, composiciones farmaceuticas y compuestos intermedios.

Legal Events

Date	Code	Title	Description
2011-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties