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ATE491722T1 - Herstellung und reinigung von il-29 - Google Patents

Herstellung und reinigung von il-29

Info

Publication number
ATE491722T1
ATE491722T1 AT06816409T AT06816409T ATE491722T1 AT E491722 T1 ATE491722 T1 AT E491722T1 AT 06816409 T AT06816409 T AT 06816409T AT 06816409 T AT06816409 T AT 06816409T AT E491722 T1 ATE491722 T1 AT E491722T1
Authority
AT
Austria
Prior art keywords
methods
production
purification
coli
vectors
Prior art date
Application number
AT06816409T
Other languages
English (en)
Inventor
Bruce Zamost
Geoffrey Lee
Robert Dedinsky
Original Assignee
Zymogenetics L L C
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics L L C, Bristol Myers Squibb Co filed Critical Zymogenetics L L C
Application granted granted Critical
Publication of ATE491722T1 publication Critical patent/ATE491722T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06816409T 2005-10-04 2006-10-04 Herstellung und reinigung von il-29 ATE491722T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72354405P 2005-10-04 2005-10-04
PCT/US2006/039139 WO2007041713A1 (en) 2005-10-04 2006-10-04 Production and purification of il-29

Publications (1)

Publication Number Publication Date
ATE491722T1 true ATE491722T1 (de) 2011-01-15

Family

ID=37603659

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06816409T ATE491722T1 (de) 2005-10-04 2006-10-04 Herstellung und reinigung von il-29

Country Status (15)

Country Link
US (6) US20080096252A1 (de)
EP (1) EP1931704B1 (de)
JP (3) JP5364375B2 (de)
AT (1) ATE491722T1 (de)
AU (1) AU2006299339B2 (de)
CA (1) CA2625208A1 (de)
CY (1) CY1112323T1 (de)
DE (1) DE602006018969D1 (de)
DK (1) DK1931704T3 (de)
ES (1) ES2357152T3 (de)
IL (2) IL189994A (de)
PL (1) PL1931704T3 (de)
PT (1) PT1931704E (de)
SI (1) SI1931704T1 (de)
WO (1) WO2007041713A1 (de)

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CL2008002053A1 (es) 2007-07-17 2009-05-22 Hoffmann La Roche Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion.
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CN102584979B (zh) * 2011-01-18 2015-10-14 北京凯因科技股份有限公司 PEG化干扰素λ
US10201584B1 (en) 2011-05-17 2019-02-12 Abbvie Inc. Compositions and methods for treating HCV
CN103228792A (zh) * 2011-08-25 2013-07-31 纳诺亘医药生物科技公司 PEG-干扰素λ1结合物
US8454947B1 (en) 2012-03-01 2013-06-04 Nanogen Pharmaceutical Biotechnology PEG-interferon lambda 1 conjugates
RU2549710C2 (ru) * 2012-06-29 2015-04-27 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Способ очистки рекомбинантного белка интерфероноподобного фактора iii типа
JP6086378B2 (ja) * 2012-11-30 2017-03-01 国立大学法人お茶の水女子大学 組み換えヒト膵臓リパーゼの調製方法
CN104045704B (zh) * 2013-03-11 2016-08-10 中国医学科学院基础医学研究所 PEG化重组人IFN-λ1、其制备方法和用途
BR112015026122A8 (pt) 2013-04-18 2020-01-21 Armo Biosciences Inc agente de polietileno glicol-il-10 (peg-il-10), seu uso, composição farmacêutica, contentor estéril e kit
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IN2013MU02416A (de) * 2013-07-19 2015-06-19 Biogenomics Ltd
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RU2016122957A (ru) 2013-11-11 2017-12-19 Армо Байосайенсиз, Инк. Способы применения интерлейкина-10 для лечения заболеваний и расстройств
CN104968673B (zh) * 2014-01-08 2018-11-02 德益阳光生物技术（北京）有限责任公司 融合多肽及使用方法
US11311519B2 (en) 2014-05-01 2022-04-26 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
US10076512B2 (en) 2014-05-01 2018-09-18 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
US10293043B2 (en) 2014-06-02 2019-05-21 Armo Biosciences, Inc. Methods of lowering serum cholesterol
CA2963989A1 (en) 2014-10-14 2016-04-21 Armo Biosciences, Inc. Interleukin-15 compositions and uses thereof
MX2017004983A (es) 2014-10-22 2017-11-13 Armo Biosciences Inc Metodos para usar interleucina 10 para tratar enfermedades y trastornos.
WO2016106229A1 (en) * 2014-12-23 2016-06-30 Armo Biosciences, Inc. Methods of improving yield in recombinant protein production
WO2016126615A1 (en) 2015-02-03 2016-08-11 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
US10835496B2 (en) 2015-04-21 2020-11-17 Eiger Biopharmaceuticals, Inc. Pharmaceutical compositions comprising lonafarnib and ritonavir
WO2016191587A1 (en) 2015-05-28 2016-12-01 Armo Biosciences, Inc. Pegylated interleukin-10 for use in treating cancer
US10398761B2 (en) 2015-08-25 2019-09-03 Armo Biosciences, Inc. Methods of using combinations of PEG-IL-10 and IL-15 for treating cancers
JP2019505553A (ja) 2016-02-19 2019-02-28 アイガー・バイオファーマシューティカルズ・インコーポレイテッドＥｉｇｅｒ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． インターフェロンラムダによるデルタ型肝炎ウイルス感染の処置
MX2019004717A (es) 2016-11-07 2019-08-05 Seattle Genetics Inc Distribucion de casquetes de cisteina modificados.
WO2020170228A1 (en) 2019-02-24 2020-08-27 Oncosimis Biotech Private Limited Method for continous production of recombinant glp-1 peptide by bacteria

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EP0626448A3 (de) * 1993-05-26 1998-01-14 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Verfahren zur Herstellung und Reinigung von alpha-Interferon
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US7038032B2 (en) * 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
CA2503305A1 (en) * 2002-10-23 2004-05-06 Zymogenetics, Inc. Methods for treating viral infection using il-28 and il-29
ES2334127T3 (es) * 2002-12-13 2010-03-05 Zymogenetics, Inc. Produccion de il-21 en huespedes procariotas.
EP2251353B1 (de) * 2003-08-07 2013-03-06 ZymoGenetics, Inc. Homogene Präparate von IL-29
CA2558829C (en) * 2004-04-02 2014-03-11 Zymogenetics, Inc. Methods for treating viral infection using il-28 and il-29 cysteine mutants
JP2008508310A (ja) * 2004-07-29 2008-03-21 ザイモジェネティクス， インコーポレイテッド がんおよび自己免疫障害を治療するためのｉｌ−２８およびｉｌ−２９の使用法
CN1305902C (zh) * 2004-11-25 2007-03-21 汕头大学医学院 一种人白细胞介素29的生产方法及重组il－29工程菌
DK1828239T3 (da) * 2004-12-10 2011-12-19 Zymogenetics Inc FGF18-produktion i prokaryote værter
WO2007013944A2 (en) * 2005-07-20 2007-02-01 Zymogenetics, Inc. Use of truncated cysteine il28 and il29 mutants to treat cancers and autoimmune disorders
ATE491722T1 (de) 2005-10-04 2011-01-15 Zymogenetics L L C Herstellung und reinigung von il-29

Also Published As

Publication number Publication date
AU2006299339B2 (en) 2012-03-15
US20100003722A1 (en) 2010-01-07
US20100222552A1 (en) 2010-09-02
EP1931704A1 (de) 2008-06-18
US8759027B2 (en) 2014-06-24
CA2625208A1 (en) 2007-04-12
EP1931704B1 (de) 2010-12-15
PL1931704T3 (pl) 2011-06-30
JP2012235789A (ja) 2012-12-06
US20120015403A1 (en) 2012-01-19
IL189994A (en) 2013-08-29
US20130143270A1 (en) 2013-06-06
JP2009510173A (ja) 2009-03-12
WO2007041713A1 (en) 2007-04-12
AU2006299339A1 (en) 2007-04-12
SI1931704T1 (sl) 2011-04-29
IL189994A0 (en) 2008-08-07
US7968315B2 (en) 2011-06-28
DK1931704T3 (da) 2011-03-14
PT1931704E (pt) 2011-03-28
CY1112323T1 (el) 2015-12-09
ES2357152T3 (es) 2011-04-19
JP2013099337A (ja) 2013-05-23
US7759092B2 (en) 2010-07-20
IL227691A0 (en) 2013-09-30
US20120271037A1 (en) 2012-10-25
DE602006018969D1 (de) 2011-01-27
JP5364375B2 (ja) 2013-12-11
US8211670B2 (en) 2012-07-03
US20080096252A1 (en) 2008-04-24

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