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ATE489462T1 - Antimikrobielles polypeptid und nutzung davon - Google Patents

Antimikrobielles polypeptid und nutzung davon

Info

Publication number
ATE489462T1
ATE489462T1 AT03725651T AT03725651T ATE489462T1 AT E489462 T1 ATE489462 T1 AT E489462T1 AT 03725651 T AT03725651 T AT 03725651T AT 03725651 T AT03725651 T AT 03725651T AT E489462 T1 ATE489462 T1 AT E489462T1
Authority
AT
Austria
Prior art keywords
nlss
polypeptide
amino acid
units
acid residues
Prior art date
Application number
AT03725651T
Other languages
English (en)
Inventor
Tetsuhiko Yoshida
Masayoshi Kume
Yoshinao Yamada
Yoko Matsuda
Hiroki Kourai
Original Assignee
Toagosei Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toagosei Co Ltd filed Critical Toagosei Co Ltd
Application granted granted Critical
Publication of ATE489462T1 publication Critical patent/ATE489462T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT03725651T 2002-04-25 2003-04-24 Antimikrobielles polypeptid und nutzung davon ATE489462T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002124830 2002-04-25
PCT/JP2003/005225 WO2003091429A1 (fr) 2002-04-25 2003-04-24 Polypeptide microbicide et ses utilisations

Publications (1)

Publication Number Publication Date
ATE489462T1 true ATE489462T1 (de) 2010-12-15

Family

ID=29267540

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03725651T ATE489462T1 (de) 2002-04-25 2003-04-24 Antimikrobielles polypeptid und nutzung davon

Country Status (8)

Country Link
US (1) US7482328B2 (de)
EP (1) EP1502949B1 (de)
JP (1) JP4423542B2 (de)
CN (1) CN1650005B (de)
AT (1) ATE489462T1 (de)
AU (1) AU2003231471A1 (de)
DE (1) DE60335101D1 (de)
WO (1) WO2003091429A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4507080B2 (ja) 2004-07-30 2010-07-21 東亞合成株式会社 抗菌ペプチド及びその利用
ES2613027T3 (es) * 2004-08-18 2017-05-22 Novabiotics Limited Péptidos antibacterianos
AU2011235933B2 (en) * 2004-08-18 2012-06-07 Novabiotics Limited Antimicrobial peptides comprising an arginine- and/or lysine-containing motif
JP4507084B2 (ja) * 2004-10-26 2010-07-21 東亞合成株式会社 アポトーシス誘導性ペプチド及びその利用
JP4730584B2 (ja) 2004-12-06 2011-07-20 東亞合成株式会社 抗菌ペプチド及びその利用
WO2006088010A1 (ja) 2005-02-15 2006-08-24 Toagosei Co., Ltd. 抗菌ペプチド及びその利用
GB0517090D0 (en) * 2005-08-19 2005-09-28 Tcp Innovations Ltd ApoE mimetic agents
JP4831410B2 (ja) * 2006-02-28 2011-12-07 東亞合成株式会社 抗ウイルス性ペプチドおよび抗ウイルス剤
JP4788958B2 (ja) * 2006-02-28 2011-10-05 東亞合成株式会社 抗ウイルス性ペプチドおよびその利用
JP5218844B2 (ja) * 2006-09-14 2013-06-26 東亞合成株式会社 人工抗菌ペプチド及びその利用
WO2008032777A1 (fr) * 2006-09-14 2008-03-20 Toagosei Co., Ltd. Peptide antibactérien et son utilisation
GB0702021D0 (en) * 2007-02-02 2007-03-14 Novabiotics Ltd Peptides and their use
EP2288616B1 (de) * 2008-06-16 2012-11-21 Chiralix B.V. Peptidylarginindeiminase-(pad-)inhibitoren
CN102321155A (zh) * 2008-12-19 2012-01-18 华中科技大学 Tnf结合肽和tnfr1封闭肽及其在治疗溃疡性结肠炎中的应用
US9238796B2 (en) 2010-06-04 2016-01-19 Toagosei Co. Ltd. Cell growth-promoting peptide and use thereof
US9018169B2 (en) * 2011-03-18 2015-04-28 Duke University Peptides for suppressing inflammation
US9303063B2 (en) 2011-03-18 2016-04-05 Duke University Peptide compounds for suppressing inflammation
WO2013180011A1 (ja) 2012-05-28 2013-12-05 東亞合成株式会社 抗菌ペプチド及びその利用
WO2014061749A1 (ja) 2012-10-18 2014-04-24 東亞合成株式会社 2型tnf受容体の発現を抑制する合成ペプチド及びその利用
CN104961801B (zh) * 2015-07-13 2018-01-19 兰州大学 一种具有多靶点的抗菌多肽偶联物及其二聚物的合成和应用
US11123400B2 (en) * 2015-09-17 2021-09-21 Seoul National University R&Db Foundation Broken or folded helical peptide or peptide analog exhibiting antimicrobial activity against gram-negative bacteria, and use thereof
CN108400003A (zh) * 2016-03-20 2018-08-14 李忠波 一种防菌抗腐蚀的变压器
CN108735372A (zh) * 2016-03-20 2018-11-02 李忠波 一种输电用防霉防菌抗腐蚀电缆
CN108084269A (zh) * 2017-12-28 2018-05-29 桂林医学院 一种多肽自组装纳米载体及其制备方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0510912T3 (da) * 1991-04-24 1998-02-09 Morinaga Milk Industry Co Ltd Antimikrobielt peptid og antimikrobielt middel
US5547939A (en) * 1991-06-14 1996-08-20 The Regents Of The University Of California Broad spectrum antimicrobial compounds and methods of use
US6063612A (en) * 1991-12-13 2000-05-16 Sri International Antiviral reagents based on RNA-binding proteins
ATE348175T1 (de) 1992-07-17 2007-01-15 Dana Farber Cancer Inst Inc Method eder intrazellularen bindung von zielgerichteten molekülen
US5789542A (en) * 1994-04-22 1998-08-04 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Amphipathic peptides
US5807746A (en) * 1994-06-13 1998-09-15 Vanderbilt University Method for importing biologically active molecules into cells
US5834184A (en) * 1995-05-17 1998-11-10 Harada; Kazuo In vivo selection of RNA-binding peptides
DE69637731D1 (de) * 1995-08-23 2008-12-11 Univ British Columbia Antimikrobielle kationische peptide und methoden zu ihrer identifizierung
JP3037605B2 (ja) * 1995-12-27 2000-04-24 ティーポール株式会社 殺菌洗浄剤組成物
EP0884058B1 (de) * 1996-02-02 2003-07-02 ASAHIKASEI AIME CO., Ltd. Losung zur aufbewahrung und zur sterilisation von kontaktlinsen
US6180604B1 (en) * 1996-08-21 2001-01-30 Micrologix Biotech Inc. Compositions and methods for treating infections using analogues of indolicidin
US5877282A (en) * 1996-09-20 1999-03-02 Bristol-Myers Squibb Company Peptide inhibitors of nuclear protein translocation having nuclear localization sequences and methods of use thereof
US5962415A (en) * 1996-09-20 1999-10-05 Bristol-Myers Squibb Co. Compositions comprising a peptide inhibitor of nuclear protein translocation and an immunosuppressant and methods of use thereof
EP0980431A1 (de) 1997-05-14 2000-02-23 Human Genome Sciences, Inc. Antimikrobielles peptid
AUPP051497A0 (en) 1997-11-24 1997-12-18 University Of Melbourne, The Antimicrobial peptides
WO1999029721A1 (en) 1997-12-10 1999-06-17 Washington University Anti-pathogen system and methods of use thereof
US6303575B1 (en) * 1998-05-12 2001-10-16 The Regents Of The University Of California Indolicidin analogs and methods of using same
EP1090032A2 (de) * 1998-06-20 2001-04-11 Washington University Membran-durchlässige peptid-komplexe für medizinischen bildgebung, diagnostik und therapie
US6476189B1 (en) * 1998-08-12 2002-11-05 National Institute Of Agrobiological Sciences Antibacterial peptides and antibacterial agents containing such peptides as an effective ingredient
WO2000009553A2 (en) 1998-08-14 2000-02-24 Bionebraska, Inc. Antimicrobial peptides isolated from the skin of american frogs
GB9918156D0 (en) 1999-08-02 1999-10-06 Zeneca Ltd Synthetic peptides
JP2003514564A (ja) * 1999-11-24 2003-04-22 エムシーエス マイクロ キャリア システムズ ゲーエムベーハー 核局在化シグナルまたはタンパク質導入領域の多量体を含むポリペプチド、および分子を細胞内へ移入するためのその使用法
JP2001186887A (ja) 2000-01-06 2001-07-10 Suntory Ltd サソリ毒由来の抗菌ペプチド
JP2002020320A (ja) * 2000-06-30 2002-01-23 Santen Pharmaceut Co Ltd 点眼液用防腐剤
CA2417454A1 (en) 2000-07-31 2002-02-07 Active Motif Peptide-mediated delivery of molecules into cells

Also Published As

Publication number Publication date
AU2003231471A1 (en) 2003-11-10
US20060057668A1 (en) 2006-03-16
US7482328B2 (en) 2009-01-27
CN1650005A (zh) 2005-08-03
DE60335101D1 (de) 2011-01-05
EP1502949A1 (de) 2005-02-02
EP1502949A4 (de) 2006-03-15
WO2003091429A1 (fr) 2003-11-06
JP4423542B2 (ja) 2010-03-03
CN1650005B (zh) 2010-12-08
EP1502949B1 (de) 2010-11-24
JPWO2003091429A1 (ja) 2005-09-02

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