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ATE486868T1 - NOVEL CHROME-2-ON DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER REUPPOST INHIBITORS - Google Patents

NOVEL CHROME-2-ON DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER REUPPOST INHIBITORS

Info

Publication number
ATE486868T1
ATE486868T1 AT07857757T AT07857757T ATE486868T1 AT E486868 T1 ATE486868 T1 AT E486868T1 AT 07857757 T AT07857757 T AT 07857757T AT 07857757 T AT07857757 T AT 07857757T AT E486868 T1 ATE486868 T1 AT E486868T1
Authority
AT
Austria
Prior art keywords
reuppost
inhibitors
derivatives
monoamine neurotransmitter
novel chrome
Prior art date
Application number
AT07857757T
Other languages
German (de)
Inventor
Dan Peters
John Redrobe
Gunnar Olsen
Elsebet Ystergaard Nielsen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Priority claimed from PCT/EP2007/064130 external-priority patent/WO2008074797A1/en
Application granted granted Critical
Publication of ATE486868T1 publication Critical patent/ATE486868T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT07857757T 2006-12-20 2007-12-18 NOVEL CHROME-2-ON DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER REUPPOST INHIBITORS ATE486868T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87580606P 2006-12-20 2006-12-20
DKPA200601678 2006-12-20
PCT/EP2007/064130 WO2008074797A1 (en) 2006-12-20 2007-12-18 Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Publications (1)

Publication Number Publication Date
ATE486868T1 true ATE486868T1 (en) 2010-11-15

Family

ID=40639626

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07857757T ATE486868T1 (en) 2006-12-20 2007-12-18 NOVEL CHROME-2-ON DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER REUPPOST INHIBITORS

Country Status (12)

Country Link
KR (1) KR20090089439A (en)
CN (1) CN101563344B (en)
AR (1) AR064457A1 (en)
AT (1) ATE486868T1 (en)
BR (1) BRPI0719578A2 (en)
DE (1) DE602007010356D1 (en)
DK (1) DK2121677T3 (en)
NZ (1) NZ577071A (en)
PT (1) PT2121677E (en)
RU (1) RU2009119919A (en)
TW (1) TW200836732A (en)
ZA (1) ZA200903278B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4159725A4 (en) 2020-05-29 2023-12-20 Daegu-Gyeongbuk Medical Innovation Foundation Carboxamide derivative and pharmaceutical composition comprising same as active ingredient for preventing or treating mental illness
KR102397705B1 (en) 2020-05-29 2022-05-13 재단법인 대구경북첨단의료산업진흥재단 5-membered heteroaryl comprising one or more N derivatives and pharmaceutical composition for use in preventing or treating mental illness containing the same as an active ingredient
JP2023528545A (en) 2020-05-29 2023-07-04 テグ－キョンプク メディカル イノベーション ファウンデーション Sulfonamide derivative and pharmaceutical composition for use in prevention or treatment of psychosis containing the same as an active ingredient

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2582297A1 (en) * 2004-09-30 2006-04-06 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Also Published As

Publication number Publication date
AR064457A1 (en) 2009-04-01
CN101563344A (en) 2009-10-21
RU2009119919A (en) 2011-01-27
NZ577071A (en) 2011-07-29
KR20090089439A (en) 2009-08-21
CN101563344B (en) 2011-11-16
PT2121677E (en) 2011-01-25
DE602007010356D1 (en) 2010-12-16
ZA200903278B (en) 2010-07-28
BRPI0719578A2 (en) 2013-12-17
TW200836732A (en) 2008-09-16
DK2121677T3 (en) 2011-02-07

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