ATE478943T1 - Wachstumsfaktormutanten mit verbesserter biologischer aktivität - Google Patents

Wachstumsfaktormutanten mit verbesserter biologischer aktivität

Info

Publication number: ATE478943T1
Authority: AT; Austria
Prior art keywords: growth factor; biological activity; improved biological; factor mutants; mutants
Prior art date: 2005-03-04

Application number

AT06723209T

Other languages

English (en)

Inventor

Stefan Mundlos

Petra Knaus

Jens Pohl

Michael Kruse

Frank Ploeger

Original Assignee

Bioph Biotech Entw Pharm Gmbh

Charite Universitaetsmedizin

Univ Berlin Freie

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-03-04

Filing date

2006-03-03

Publication date

2010-09-15

2006-03-03 Application filed by Bioph Biotech Entw Pharm Gmbh, Charite Universitaetsmedizin, Univ Berlin Freie filed Critical Bioph Biotech Entw Pharm Gmbh

2010-09-15 Application granted granted Critical

2010-09-15 Publication of ATE478943T1 publication Critical patent/ATE478943T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Gastroenterology & Hepatology (AREA)
Physical Education & Sports Medicine (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Zoology (AREA)
Psychology (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Dermatology (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Orthopedic Medicine & Surgery (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT06723209T 2005-03-04 2006-03-03 Wachstumsfaktormutanten mit verbesserter biologischer aktivität ATE478943T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP05004840A EP1698691A1 (de)	2005-03-04	2005-03-04	Mutanten von Wachstumsfaktoren mit verbesserter biologischer Eigenschaft
PCT/EP2006/001966 WO2006094722A2 (en)	2005-03-04	2006-03-03	Growth factor mutants with improved biological activity

Publications (1)

Publication Number	Publication Date
ATE478943T1 true ATE478943T1 (de)	2010-09-15

Family

ID=35431619

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06723209T ATE478943T1 (de)	2005-03-04	2006-03-03	Wachstumsfaktormutanten mit verbesserter biologischer aktivität

Country Status (10)

Country	Link
US (1)	US9012401B2 (de)
EP (2)	EP1698691A1 (de)
JP (1)	JP2008538073A (de)
AT (1)	ATE478943T1 (de)
AU (1)	AU2006222283B2 (de)
CA (1)	CA2600951A1 (de)
DE (1)	DE602006016406D1 (de)
DK (1)	DK1856249T3 (de)
ES (1)	ES2348404T3 (de)
WO (1)	WO2006094722A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1915986A1 (de) *	2006-10-23	2008-04-30	BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH	Wachstumsfaktorhaltige Lipidformulierungen
EP2019117A1 (de) *	2007-07-27	2009-01-28	BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH	Optimiertes Reinigungsverfahren für rekombinantes Wachstumsfaktorprotein
CA2806143A1 (en) *	2010-07-30	2012-02-02	Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mb H	Drug delivery devices and growth factor formulations for accelerated wound healing
EP2537538A1 (de)	2011-06-22	2012-12-26	Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH	Bioresorbierbarer Wundverband
EP2602264A1 (de) *	2011-12-05	2013-06-12	Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH	GDF-5-Mutant zur Induzierung der Knorpelbildung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL110589A0 (en) *	1993-08-10	1994-11-11	Bioph Biotech Entw Pharm Gmbh	Growth/differentiation factor of the TGF- beta family
EP1115866A1 (de)	1998-09-22	2001-07-18	University of Maryland at Baltimore	Mutanten der cysteinknoten-wachstumsfaktoren familie
US6677432B1 (en) *	1998-10-07	2004-01-13	Stryker Corporation	Mutations of the C-terminal portion of TGF-β superfamily proteins
US20110039773A1 (en) *	2007-12-21	2011-02-17	Stryker Biotech	BMP Mutants with Decreased Susceptibility to Noggin

2005
- 2005-03-04 EP EP05004840A patent/EP1698691A1/de not_active Withdrawn
2006
- 2006-03-03 ES ES06723209T patent/ES2348404T3/es active Active
- 2006-03-03 AT AT06723209T patent/ATE478943T1/de not_active IP Right Cessation
- 2006-03-03 EP EP06723209A patent/EP1856249B1/de not_active Not-in-force
- 2006-03-03 JP JP2007557437A patent/JP2008538073A/ja active Pending
- 2006-03-03 AU AU2006222283A patent/AU2006222283B2/en not_active Ceased
- 2006-03-03 CA CA002600951A patent/CA2600951A1/en not_active Abandoned
- 2006-03-03 DK DK06723209.0T patent/DK1856249T3/da active
- 2006-03-03 WO PCT/EP2006/001966 patent/WO2006094722A2/en active Application Filing
- 2006-03-03 DE DE602006016406T patent/DE602006016406D1/de active Active
- 2006-03-03 US US11/817,735 patent/US9012401B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ES2348404T3 (es)	2010-12-03
US20080260830A1 (en)	2008-10-23
US9012401B2 (en)	2015-04-21
EP1698691A1 (de)	2006-09-06
DE602006016406D1 (de)	2010-10-07
EP1856249A2 (de)	2007-11-21
DK1856249T3 (da)	2010-11-15
JP2008538073A (ja)	2008-10-09
AU2006222283A1 (en)	2006-09-14
WO2006094722A2 (en)	2006-09-14
CA2600951A1 (en)	2006-09-14
WO2006094722A3 (en)	2007-02-01
AU2006222283B2 (en)	2011-06-09
EP1856249B1 (de)	2010-08-25

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Legal Events

Date	Code	Title	Description
2011-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties