US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
US20040049014A1
(en)
*
|
1988-12-28 |
2004-03-11 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
DK0695189T3
(da)
*
|
1992-12-29 |
1999-08-09 |
Genentech Inc |
Behandling af inflammatorisk tarmsygdom med IFN-gammainhibitorer
|
US20030059428A1
(en)
*
|
1993-02-26 |
2003-03-27 |
Boris Skurkovich |
Treatment of autoimmune diseases
|
US20030228310A1
(en)
*
|
1996-12-23 |
2003-12-11 |
Advanced Biotherapy, Inc. |
Treatment of skin diseases
|
US20030086925A1
(en)
*
|
1996-12-23 |
2003-05-08 |
Advanced Biotherapy, Inc. |
Treatment of autoimmune diseases
|
US20030223995A1
(en)
*
|
1996-12-23 |
2003-12-04 |
Advanced Biotherapy, Inc. |
Treatment of pemphigus vulgaris
|
ATE293994T1
(de)
*
|
1997-12-01 |
2005-05-15 |
Fang Fang |
Multivalente rekombinante antikörper zur behandlung von hrv infektionen
|
US20030035798A1
(en)
*
|
2000-08-16 |
2003-02-20 |
Fang Fang |
Humanized antibodies
|
DE69942671D1
(de)
*
|
1998-12-01 |
2010-09-23 |
Facet Biotech Corp |
Humanisierte antikoerper gegen gamma-interferon
|
JP3579355B2
(ja)
*
|
1998-12-09 |
2004-10-20 |
プロテイン デザイン ラブス インコーポレイティド |
ヒトの乾癬を予防及び治療するための乾癬モデル動物
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
US7087726B2
(en)
*
|
2001-02-22 |
2006-08-08 |
Genentech, Inc. |
Anti-interferon-α antibodies
|
AU2002365196C1
(en)
|
2001-07-19 |
2009-08-13 |
Perlan Therapeutics, Inc. |
Multimeric proteins and methods of making and using same
|
US7084257B2
(en)
|
2001-10-05 |
2006-08-01 |
Amgen Inc. |
Fully human antibody Fab fragments with human interferon-gamma neutralizing activity
|
CN102180944A
(zh)
|
2001-10-10 |
2011-09-14 |
诺和诺德公司 |
肽的重构和糖缀合
|
EP2298354B1
(de)
|
2001-10-10 |
2014-03-19 |
ratiopharm GmbH |
Neumodulierung und Glykokonjugation von Interferon-beta
|
US7244592B2
(en)
|
2002-03-07 |
2007-07-17 |
Dyax Corp. |
Ligand screening and discovery
|
NZ570998A
(en)
|
2002-03-15 |
2010-08-27 |
Schering Corp |
Method of diagnosising allergy or asthma by using a CD200Ra antibody
|
CA2486147A1
(en)
*
|
2002-05-17 |
2003-11-27 |
Protein Design Labs, Inc. |
Treatment of crohn's disease or psoriasis using anti-inteferon gamma antibodies
|
US20040052791A1
(en)
*
|
2002-05-22 |
2004-03-18 |
Rolf Ehrhardt |
Treatment of Crohn's disease or psoriasis using anti-interferon gamma antibodies
|
US20050019323A1
(en)
*
|
2002-05-22 |
2005-01-27 |
Protein Design Labs, Inc. |
Treatment of Crohn's disease or psoriasis using anti-interferon gamma antibodies
|
US20040052790A1
(en)
*
|
2002-09-18 |
2004-03-18 |
Advanced Biotherapy, Inc. |
Treatment of schizophrenia
|
US7361740B2
(en)
|
2002-10-15 |
2008-04-22 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
US7217797B2
(en)
*
|
2002-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
US7365168B2
(en)
*
|
2002-10-15 |
2008-04-29 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
WO2004034988A2
(en)
*
|
2002-10-16 |
2004-04-29 |
Amgen Inc. |
Human anti-ifn-ϝ neutralizing antibodies as selective ifn-ϝ pathway inhibitors
|
AU2002347978B2
(en)
*
|
2002-10-17 |
2009-10-08 |
Amgen Inc. |
Fully human antibody fab fragments with human interferon-gamma neutralizing activity
|
WO2004041862A2
(en)
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
|
PT1572106E
(pt)
|
2002-11-15 |
2010-06-17 |
Novartis Vaccines & Diagnostic |
Métodos para prevenção e tratamento de metástase de cancro e perda óssea associada a metástase de cancro
|
EP1587834B1
(de)
|
2002-12-23 |
2011-07-06 |
Schering Corporation |
Verwendungen von säuger-cytokin il-23 ; verwandte reagenzien
|
NZ541898A
(en)
|
2003-03-10 |
2008-07-31 |
Schering Corp |
Uses of IL-23 antagonists for the manufacture of a medicament for the treatment of tumors
|
JP4685764B2
(ja)
*
|
2003-04-10 |
2011-05-18 |
アボット バイオセラピューティクス コーポレイション |
変異誘発による抗体のFcRn結合親和力又は血清半減期の改変
|
EP1673395A1
(de)
*
|
2003-10-15 |
2006-06-28 |
PDL BioPharma, Inc. |
Veränderungen der serum-halbwertszeiten von fc-fusionsprotein durch mutagenese der position 250, 314 und/oder 428 der schweren kette der konstanten region von ig
|
NZ549040A
(en)
|
2004-02-17 |
2009-07-31 |
Schering Corp |
Use for interleukin-33 (IL33) and the IL-33 receptor complex
|
ES2671522T3
(es)
|
2004-04-02 |
2018-06-06 |
The Regents Of The University Of California |
Métodos y composiciones para tratar y prevenir una enfermedad asociada con la integrina alfa V beta 5
|
US7794713B2
(en)
|
2004-04-07 |
2010-09-14 |
Lpath, Inc. |
Compositions and methods for the treatment and prevention of hyperproliferative diseases
|
US20050276806A1
(en)
*
|
2004-06-15 |
2005-12-15 |
Advanced Biotherapy, Inc. |
Treatment of autism
|
WO2006068987A2
(en)
|
2004-12-20 |
2006-06-29 |
Schering Corporation |
Uses of il-23 antagonists in the treatment of diabetes mellitus
|
EP1841455A1
(de)
*
|
2005-01-24 |
2007-10-10 |
Amgen Inc. |
Humanisierter anti-amyloid-antikörper
|
EP1848744B1
(de)
|
2005-01-27 |
2012-01-18 |
Novimmune SA |
Humane anti-interferon-gamma-antikörper und verfahren zu ihrer verwendung
|
EP3623473A1
(de)
*
|
2005-03-31 |
2020-03-18 |
Chugai Seiyaku Kabushiki Kaisha |
Verfahren zur herstellung von polypeptiden durch regulierung der anordnung
|
ES2538036T3
(es)
*
|
2005-07-28 |
2015-06-16 |
Novartis Ag |
Uso de anticuerpo a M-CSF
|
EP1913027B1
(de)
*
|
2005-07-28 |
2015-03-04 |
Novartis AG |
M-csf-spezifische monoklonale antikörper und anwendungen davon
|
NZ566424A
(en)
|
2005-09-01 |
2011-10-28 |
Schering Corp |
Use of IL-23 and IL-17 antagonists to treat autoimmune ocular inflammatory disease
|
MX2008005405A
(es)
*
|
2005-10-28 |
2008-09-11 |
Florida Internat University Bo |
Anticuerpos quimericos equinos: humanos.
|
EP3345616A1
(de)
|
2006-03-31 |
2018-07-11 |
Chugai Seiyaku Kabushiki Kaisha |
Antikörpermodifizierungsverfahren zur reinigung von bispezifischem antikörper
|
JP5624276B2
(ja)
*
|
2006-03-31 |
2014-11-12 |
中外製薬株式会社 |
抗体の血中動態を制御する方法
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之c-kit抗體
|
US7862812B2
(en)
|
2006-05-31 |
2011-01-04 |
Lpath, Inc. |
Methods for decreasing immune response and treating immune conditions
|
CN101626783A
(zh)
*
|
2006-08-04 |
2010-01-13 |
诺华有限公司 |
Ephb3-特异性抗体和其应用
|
CA2661023C
(en)
|
2006-08-18 |
2017-08-15 |
Novartis Ag |
Prlr-specific antibody and uses thereof
|
ZA200902860B
(en)
*
|
2006-10-27 |
2010-07-28 |
Lpath Inc |
Compositions and methods for binding sphingosine-1-phosphate
|
US8444970B2
(en)
*
|
2006-10-27 |
2013-05-21 |
Lpath, Inc. |
Compositions and methods for treating ocular diseases and conditions
|
US8377439B2
(en)
|
2006-12-07 |
2013-02-19 |
Novartis Ag |
Antagonist antibodies against EPHB3
|
WO2008097461A2
(en)
*
|
2007-02-02 |
2008-08-14 |
Amgen Inc |
Hepcidin and hepcidin antibodies
|
JP5337055B2
(ja)
|
2007-02-28 |
2013-11-06 |
メルク・シャープ・アンド・ドーム・コーポレーション |
免疫性障害の処置のための組合せ治療
|
CA2724432A1
(en)
|
2007-05-30 |
2008-12-11 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
US9163091B2
(en)
*
|
2007-05-30 |
2015-10-20 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
US7709215B2
(en)
|
2007-06-01 |
2010-05-04 |
Cytonics Corporation |
Method for diagnosing and treating acute joint injury
|
NZ601946A
(en)
|
2007-06-25 |
2013-12-20 |
Esbatech Alcon Biomed Res Unit |
Methods of modifying antibodies, and modified antibodies with improved functional properties
|
ES2687808T3
(es)
|
2007-09-26 |
2018-10-29 |
Chugai Seiyaku Kabushiki Kaisha |
Región constante de anticuerpo modificado
|
US9096651B2
(en)
|
2007-09-26 |
2015-08-04 |
Chugai Seiyaku Kabushiki Kaisha |
Method of modifying isoelectric point of antibody via amino acid substitution in CDR
|
US8361465B2
(en)
|
2007-10-26 |
2013-01-29 |
Lpath, Inc. |
Use of anti-sphingosine-1-phosphate antibodies in combination with chemotherapeutic agents
|
TW201634479A
(zh)
|
2007-12-05 |
2016-10-01 |
Chugai Pharmaceutical Co Ltd |
抗nr10抗體及其應用
|
WO2009085200A2
(en)
|
2007-12-21 |
2009-07-09 |
Amgen Inc. |
Anti-amyloid antibodies and uses thereof
|
WO2009094551A1
(en)
|
2008-01-25 |
2009-07-30 |
Amgen Inc. |
Ferroportin antibodies and methods of use
|
TR201808046T4
(tr)
|
2008-04-11 |
2018-06-21 |
Chugai Pharmaceutical Co Ltd |
İki veya daha fazla sayıda antijen molekülüne tekrar tekrar bağlanabilen antijen bağlanma molekülü.
|
EP2816059A1
(de)
|
2008-05-01 |
2014-12-24 |
Amgen, Inc |
Anti-Hepcidin-Antikörper und Verfahren zu ihrer Verwendung
|
EP2288379A4
(de)
|
2008-05-19 |
2012-08-08 |
Advaxis |
Doppeltes freisetzungssystem für heterologe antigene
|
US9650639B2
(en)
|
2008-05-19 |
2017-05-16 |
Advaxis, Inc. |
Dual delivery system for heterologous antigens
|
US9017660B2
(en)
|
2009-11-11 |
2015-04-28 |
Advaxis, Inc. |
Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors
|
TWI440469B
(zh)
|
2008-09-26 |
2014-06-11 |
Chugai Pharmaceutical Co Ltd |
Improved antibody molecules
|
CA2740871A1
(en)
*
|
2008-10-16 |
2010-04-22 |
Cytonics Corporation |
Biomarkers and methods for detecting and treating spinal and joint pain
|
US8871202B2
(en)
|
2008-10-24 |
2014-10-28 |
Lpath, Inc. |
Prevention and treatment of pain using antibodies to sphingosine-1-phosphate
|
US8401799B2
(en)
*
|
2008-12-05 |
2013-03-19 |
Lpath, Inc. |
Antibody design using anti-lipid antibody crystal structures
|
WO2010065921A2
(en)
*
|
2008-12-05 |
2010-06-10 |
Lpath, Inc. |
Antibody design using anti-lipid antibody crystal structures
|
WO2010098863A1
(en)
*
|
2009-02-26 |
2010-09-02 |
Lpath, Inc. |
Humanized platelet activating factor antibody design using anti-lipid antibody templates
|
EP2409991B1
(de)
|
2009-03-19 |
2017-05-03 |
Chugai Seiyaku Kabushiki Kaisha |
Variante einer konstanten antikörperregion
|
TWI682995B
(zh)
|
2009-03-19 |
2020-01-21 |
日商中外製藥股份有限公司 |
抗體恆定區域改變體
|
EP2419446A4
(de)
*
|
2009-04-17 |
2013-01-23 |
Lpath Inc |
Humanisierte antikörperzusammensetzungen und verfahren zur bindung von lysophosphatidsäure
|
MX2011012136A
(es)
|
2009-05-15 |
2012-04-10 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-axl.
|
EP2456460A4
(de)
|
2009-07-24 |
2013-02-20 |
Univ California |
Verfahren und zusammensetzungen zur behandlung und prävention von mit avb5-integrin assoziierten krankheiten
|
AU2010276580A1
(en)
|
2009-07-31 |
2012-03-15 |
Medarex, L.L.C. |
Fully human antibodies to BTLA
|
US10150808B2
(en)
|
2009-09-24 |
2018-12-11 |
Chugai Seiyaku Kabushiki Kaisha |
Modified antibody constant regions
|
US10016617B2
(en)
|
2009-11-11 |
2018-07-10 |
The Trustees Of The University Of Pennsylvania |
Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers
|
PL2529033T3
(pl)
|
2010-01-26 |
2017-10-31 |
Nat Jewish Health |
Sposoby do przewidywania ryzyka, diagnozowania i prognozowania zaburzeń płucnych
|
US20110212088A1
(en)
*
|
2010-02-26 |
2011-09-01 |
Sabbadini Roger A |
Anti-paf antibodies
|
WO2011108714A1
(ja)
|
2010-03-04 |
2011-09-09 |
中外製薬株式会社 |
抗体定常領域改変体
|
CN103282048B
(zh)
|
2010-10-01 |
2017-05-17 |
宾夕法尼亚大学理事会 |
李斯特菌疫苗载体用于在寄生虫感染的个体中扭转免疫无应答的用途
|
DK2644698T3
(en)
|
2010-11-17 |
2018-01-22 |
Chugai Pharmaceutical Co Ltd |
MULTI-SPECIFIC ANTIGEN-BINDING MOLECULE WITH ALTERNATIVE FUNCTION TO BLOOD COAGULATION FACTOR FUNCTION VIII
|
RU2642318C2
(ru)
|
2010-11-30 |
2018-01-24 |
Чугаи Сейяку Кабусики Кайся |
Антигенсвязывающая молекула, способная многократно связываться с множеством антигенных молекул
|
EP2679681B2
(de)
|
2011-02-25 |
2023-11-15 |
Chugai Seiyaku Kabushiki Kaisha |
FcgammaRIIB-spezifischer Fc Antikörper
|
WO2012125551A1
(en)
|
2011-03-11 |
2012-09-20 |
Advaxis |
Listeria-based adjuvants
|
TW201817744A
(zh)
|
2011-09-30 |
2018-05-16 |
日商中外製藥股份有限公司 |
具有促進抗原清除之FcRn結合域的治療性抗原結合分子
|
EP2762493B1
(de)
|
2011-09-30 |
2021-06-09 |
Chugai Seiyaku Kabushiki Kaisha |
Antigenbindende moleküle zur förderung der zersetzung von antigenen mit mehreren biologischen aktivitäten
|
CA2854921A1
(en)
|
2011-11-23 |
2013-05-30 |
Amgen Inc. |
Methods of treatment using an antibody against interferon gamma
|
JP2015511602A
(ja)
|
2012-03-12 |
2015-04-20 |
アドバクシス, インコーポレイテッド |
リステリアワクチン処理後のサプレッサー細胞機能抑制
|
EP2877494B1
(de)
|
2012-07-23 |
2020-07-15 |
La Jolla Institute for Allergy and Immunology |
Ptprs und proteoglykane bei autoimmunkrankheiten
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
US9969804B2
(en)
|
2013-04-01 |
2018-05-15 |
The Regents Of The University Of California |
Methods and compositions for treating and preventing disease associated with alpha-V beta-8 integrin
|
CA2920113A1
(en)
|
2013-08-20 |
2015-02-26 |
Merck Sharp & Dohme Corp. |
Treating cancer with a combination of a pd-1 antagonist and dinaciclib
|
AR097306A1
(es)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
Modulación de la inmunidad tumoral
|
KR102522346B1
(ko)
|
2013-08-29 |
2023-04-17 |
시티 오브 호프 |
세포침투 콘주게이트 및 이의 사용 방법
|
AU2014325063B2
(en)
|
2013-09-27 |
2019-10-31 |
Chugai Seiyaku Kabushiki Kaisha |
Method for producing polypeptide heteromultimer
|
US20160304969A1
(en)
|
2013-12-17 |
2016-10-20 |
Merck Sharp & Dohme Corp. |
Ifn-gamma gene signature biomarkers of tumor response to pd-1 antagonists
|
ES2899457T3
(es)
|
2014-02-04 |
2022-03-11 |
Pfizer |
Combinación de un antagonista de PD-1 y un inhibidor de VEGFR para tratar el cáncer
|
JP2017508785A
(ja)
|
2014-02-04 |
2017-03-30 |
インサイト・コーポレイションIncyte Corporation |
癌を治療するためのpd−1アンタゴニストおよびido1阻害剤の組み合わせ
|
JP2017517506A
(ja)
|
2014-05-21 |
2017-06-29 |
ファイザー・インコーポレイテッド |
癌を処置するための抗ccr4抗体および4−1bbアゴニストの併用
|
WO2016004383A1
(en)
|
2014-07-03 |
2016-01-07 |
City Of Hope |
Tumor-selective ctla-4 antagonists
|
MA40475A
(fr)
|
2014-08-19 |
2017-06-28 |
Fayadat Dilman Laurence |
Anticorps anti-tigit
|
JO3663B1
(ar)
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
EP3185866A1
(de)
|
2014-08-25 |
2017-07-05 |
Pfizer Inc. |
Kombination aus einem pd-1-antagonisten und einem alk-inhibitor zur behandlung von krebs
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
MY181199A
(en)
|
2014-12-19 |
2020-12-21 |
Chugai Pharmaceutical Co Ltd |
Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
|
HUE056489T2
(hu)
|
2014-12-19 |
2022-02-28 |
Chugai Pharmaceutical Co Ltd |
Anti-C5 antitestek és alkalmazási eljárások
|
ES2789351T3
(es)
|
2015-01-13 |
2020-10-26 |
Hope City |
Máscaras de enlace peptídico de proteínas de unión a CTLA4
|
MX2017009272A
(es)
|
2015-01-16 |
2018-04-11 |
|
Anticuerpos que penetran en células.
|
EA201791754A1
(ru)
|
2015-02-05 |
2019-01-31 |
Чугаи Сейяку Кабусики Кайся |
АНТИТЕЛА, СОДЕРЖАЩИЕ ЗАВИСЯЩИЙ ОТ КОНЦЕНТРАЦИИ ИОНОВ АНТИГЕНСВЯЗЫВАЮЩИЙ ДОМЕН, ВАРИАНТЫ Fc-ОБЛАСТИ, IL-8-СВЯЗЫВАЮЩИЕ АНТИТЕЛА И ИХ ПРИМЕНЕНИЯ
|
JP6130983B2
(ja)
|
2015-02-27 |
2017-05-17 |
中外製薬株式会社 |
Il−6関連疾患治療用組成物
|
CA2978311A1
(en)
|
2015-03-04 |
2016-09-09 |
Merck Sharp & Dohme Corp. |
Combination of a pd-1 antagonist and eribulin for treating cancer
|
AU2015384801B2
(en)
|
2015-03-04 |
2022-01-06 |
Eisai R&D Management Co., Ltd. |
Combination of a PD-1 antagonist and a VEGFR/FGFR/RET tyrosine kinase inhibitor for treating cancer
|
CN107614523A
(zh)
|
2015-03-30 |
2018-01-19 |
希望之城 |
机械互锁复合物
|
WO2016159213A1
(ja)
|
2015-04-01 |
2016-10-06 |
中外製薬株式会社 |
ポリペプチド異種多量体の製造方法
|
US11091543B2
(en)
|
2015-05-07 |
2021-08-17 |
Swedish Orphan Biovitrum Ag |
Methods, compositions and dosing regimens for treating or preventing interferon-gamma related indications
|
BR112017023867A2
(pt)
|
2015-05-07 |
2018-07-24 |
Novimmune Sa |
métodos e composições para diagnóstico e tratamento de distúrbios em pacientes com níveis elevados de cxcl9 e outros biomarcadores
|
DK3294764T3
(da)
|
2015-05-15 |
2021-01-25 |
Hope City |
Kimæriske antigenreceptor sammensætninger
|
CA2986126A1
(en)
|
2015-05-29 |
2016-12-08 |
Merck Sharp & Dohme Corp. |
Combination of a pd-1 antagonist and cpg-c type oligonucleotide for treating cancer
|
CN114306627A
(zh)
|
2015-08-06 |
2022-04-12 |
希望之城 |
细胞穿透蛋白-抗体缀合物及其使用方法
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
EP3344657A1
(de)
|
2015-09-02 |
2018-07-11 |
The Regents of the University of Colorado, A Body Corporate |
Zusammensetzungen und verfahren zur modulation einer t-zell-vermittelten immunreaktion
|
CA3007997A1
(en)
|
2015-12-10 |
2017-06-15 |
City Of Hope |
Cell penetrating cyanine-coupled antibodies
|
WO2017106129A1
(en)
|
2015-12-16 |
2017-06-22 |
Merck Sharp & Dohme Corp. |
Anti-lag3 antibodies and antigen-binding fragments
|
US10912776B2
(en)
|
2015-12-24 |
2021-02-09 |
Corvus Pharmaceuticals, Inc. |
Methods of treating cancer
|
US11359009B2
(en)
|
2015-12-25 |
2022-06-14 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-myostatin antibodies and methods of use
|
US11649262B2
(en)
|
2015-12-28 |
2023-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Method for promoting efficiency of purification of Fc region-containing polypeptide
|
US10053515B2
(en)
|
2016-01-22 |
2018-08-21 |
Merck Sharp & Dohme Corp. |
Anti-coagulation factor XI antibodies
|
EP3408294A1
(de)
|
2016-01-25 |
2018-12-05 |
Pfizer Inc. |
Kombination aus einem monoklonalen antikörper ox40-agonist und 4-1bb-agonist zur behandlung von krebs
|
TW201735947A
(zh)
|
2016-03-14 |
2017-10-16 |
Chugai Pharmaceutical Co Ltd |
用於癌之治療的細胞傷害誘導治療劑
|
US11230591B2
(en)
|
2016-04-20 |
2022-01-25 |
Merck Sharp & Dohme Corp. |
CMV neutralizing antigen binding proteins
|
JP7022081B2
(ja)
|
2016-06-14 |
2022-02-17 |
メルク・シャープ・アンド・ドーム・コーポレーション |
抗凝固因子xi抗体
|
NL2017267B1
(en)
|
2016-07-29 |
2018-02-01 |
Aduro Biotech Holdings Europe B V |
Anti-pd-1 antibodies
|
NL2017270B1
(en)
|
2016-08-02 |
2018-02-09 |
Aduro Biotech Holdings Europe B V |
New anti-hCTLA-4 antibodies
|
KR102538749B1
(ko)
|
2016-08-05 |
2023-06-01 |
추가이 세이야쿠 가부시키가이샤 |
Il-8 관련 질환의 치료용 또는 예방용 조성물
|
JOP20190055A1
(ar)
|
2016-09-26 |
2019-03-24 |
Merck Sharp & Dohme |
أجسام مضادة ضد cd27
|
SG11201902974PA
(en)
|
2016-10-14 |
2019-05-30 |
Merck Sharp & Dohme |
Combination of a pd-1 antagonist and eribulin for treating urothelial cancer
|
IL266174B2
(en)
*
|
2016-10-24 |
2024-10-01 |
Novimmune Sa |
Methods, compositions and dosage regimens for the treatment or prevention of interferon-gamma-related indications
|
AU2017348365A1
(en)
|
2016-10-28 |
2019-05-23 |
Astute Medical, Inc. |
Use of antibodies to TIMP-2 for the improvement of renal function
|
US11008325B2
(en)
|
2016-11-14 |
2021-05-18 |
Virginia Commonwealth University |
Inhibitors of cancer invasion, attachment, and/or metastasis
|
MX2019012233A
(es)
|
2017-04-13 |
2020-01-14 |
Aduro Biotech Holdings Europe Bv |
Anticuerpos anti-sirpa.
|
SG11201909955XA
(en)
|
2017-05-02 |
2019-11-28 |
Merck Sharp & Dohme |
Formulations of anti-lag3 antibodies and co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies
|
JOP20190260A1
(ar)
|
2017-05-02 |
2019-10-31 |
Merck Sharp & Dohme |
صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
|
US11851486B2
(en)
|
2017-05-02 |
2023-12-26 |
National Center Of Neurology And Psychiatry |
Method for predicting and evaluating therapeutic effect in diseases related to IL-6 and neutrophils
|
JOP20190256A1
(ar)
|
2017-05-12 |
2019-10-28 |
Icahn School Med Mount Sinai |
فيروسات داء نيوكاسل واستخداماتها
|
US11680110B2
(en)
|
2017-07-31 |
2023-06-20 |
Hoffmann-La Roche Inc. |
Three-dimensional structure-based humanization method
|
US20200354452A1
(en)
|
2017-09-29 |
2020-11-12 |
City Of Hope |
Cars and bispecific antibodies for treatment of mantle cell lymphoma
|
JOP20200131A1
(ar)
|
2017-11-17 |
2020-05-28 |
Merck Sharp & Dohme |
أجسام مضادة خاصة بنسخة تشبه جلوبيولين مناعي 3 (ilt3) واستخدامتها
|
WO2019148412A1
(en)
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1/lag3 bispecific antibodies
|
EP3774916A2
(de)
|
2018-04-06 |
2021-02-17 |
Biolegend, Inc. |
Anti-tetraspanin-33-wirkstoffe und -zusammensetzungen und verfahren zur herstellung und verwendung davon
|
US20210395329A1
(en)
|
2018-06-29 |
2021-12-23 |
City Of Hope |
Cd6 targeted chimeric antigen receptors for treatent of certain autoimmune disorders
|
WO2020041758A1
(en)
|
2018-08-24 |
2020-02-27 |
City Of Hope |
Masked cytokine conjugates
|
EP3849606A4
(de)
|
2018-09-13 |
2022-06-29 |
Merck Sharp & Dohme Corp. |
Kombination aus einem pd-1-antagonisten und einem lag3-antagonisten zur behandlung von kolorektalem krebs mit nicht-mikrosatelliteninstabilität/kompetenter fehlanpassungsreparatur
|
JP2022501388A
(ja)
|
2018-09-19 |
2022-01-06 |
ラホヤ インスティチュート フォー イミュノロジー |
関節リウマチにおけるptprs及びプロテオグリカン
|
CN113365697B
(zh)
|
2018-09-25 |
2024-07-19 |
百进生物科技公司 |
抗tlr9药剂和组合物及其制备方法和使用方法
|
JP2022512346A
(ja)
|
2018-12-18 |
2022-02-03 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
レプチン受容体、gdf8、およびアクチビンaに対するアンタゴニストを使用して、体重および除脂肪筋肉量を増やすための組成物および方法
|
US20220370606A1
(en)
|
2018-12-21 |
2022-11-24 |
Pfizer Inc. |
Combination Treatments Of Cancer Comprising A TLR Agonist
|
CA3136568A1
(en)
|
2019-05-13 |
2020-11-19 |
Regeneron Pharmaceuticals, Inc. |
Combination of pd-1 inhibitors and lag-3 inhibitors for enhanced efficacy in treating cancer
|
WO2020240360A1
(en)
|
2019-05-24 |
2020-12-03 |
Pfizer Inc. |
Combination therapies using cdk inhibitors
|
AU2020281535A1
(en)
|
2019-05-24 |
2022-01-27 |
Merck Patent Gmbh |
Combination therapies using CDK inhibitors
|
AU2020292283A1
(en)
|
2019-06-11 |
2021-12-23 |
Regeneron Pharmaceuticals, Inc. |
Anti-PcrV antibodies that bind PcrV, compositions comprising anti-PcrV antibodies, and methods of use thereof
|
CA3155672A1
(en)
|
2019-10-29 |
2021-05-06 |
Yoichi Ozawa |
Combination of a pd-1 antagonist, a vegfr/fgfr/ret tyrosine kinase inhibitor and a cbp/beta-catenin inhibitor for treating cancer
|
WO2021138454A1
(en)
|
2019-12-30 |
2021-07-08 |
City Of Hope |
Methods of making and using regulatory t cells and effector t cells having chimeric antigen receptors targeted to cd6, cd19, and/or an il-13r for treatment of autoimmune disorders and cancers
|
WO2021146383A1
(en)
|
2020-01-17 |
2021-07-22 |
BioLegend, Inc. |
Anti-tlr7 agents and compositions and methods for making and using the same
|
EP4118105A2
(de)
|
2020-03-09 |
2023-01-18 |
Pfizer Inc. |
Cd80-fc-fusionsprotein und verwendungen davon
|
CN115996951A
(zh)
|
2020-04-30 |
2023-04-21 |
赛罗帕私人有限公司 |
抗cd103抗体
|
JP2023524854A
(ja)
|
2020-05-13 |
2023-06-13 |
ファイザー・インク |
がんを処置するための方法、治療、および使用
|
MX2022016322A
(es)
|
2020-06-25 |
2023-01-24 |
Merck Sharp & Dohme Llc |
Anticuerpos de alta afinidad dirigidos a tau fosforilada en la serina 413.
|
WO2022003554A1
(en)
|
2020-07-01 |
2022-01-06 |
Pfizer Inc. |
Biomarkers for pd-1 axis binding antagonist therapy
|
WO2022035998A1
(en)
|
2020-08-11 |
2022-02-17 |
City Of Hope |
Compositions and uses of sars-cov-2 targeted chimeric antigen receptor modified nk cells
|
CA3189987A1
(en)
|
2020-09-02 |
2022-03-10 |
Pharmabcine Inc. |
Combination therapy of a pd-1 antagonist and an antagonist for vegfr-2 for treating patients with cancer
|
JP2023540795A
(ja)
|
2020-09-14 |
2023-09-26 |
ファイザー・インク |
がんを処置するための方法、治療、および使用
|
KR20230074516A
(ko)
|
2020-09-24 |
2023-05-30 |
머크 샤프 앤드 돔 엘엘씨 |
프로그램화된 사멸 수용체 1 (pd-1) 항체 및 히알루로니다제 변이체 및 그의 단편의 안정한 제제 및 그의 사용 방법
|
WO2022093641A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2a agents and compositions and methods for making and using the same
|
WO2022093640A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2c agents and compositions and methods for making and using the same
|
AR124712A1
(es)
|
2021-01-29 |
2023-04-26 |
Merck Sharp & Dohme |
Composiciones de anticuerpos del receptor de muerte programada 1 (pd-1) y métodos para obtener las composiciones de los mismos
|
CN112794903B
(zh)
*
|
2021-04-14 |
2021-06-25 |
广州市雷德生物科技有限公司 |
一种特异性结合IFN-γ的抗体及其应用
|
WO2023057882A1
(en)
|
2021-10-05 |
2023-04-13 |
Pfizer Inc. |
Combinations of azalactam compounds with a pd-1 axis binding antagonist for the treatment of cancer
|
WO2023079428A1
(en)
|
2021-11-03 |
2023-05-11 |
Pfizer Inc. |
Combination therapies using tlr7/8 agonist
|
WO2023186756A1
(en)
|
2022-03-28 |
2023-10-05 |
F. Hoffmann-La Roche Ag |
Interferon gamma variants and antigen binding molecules comprising these
|
WO2024020051A1
(en)
|
2022-07-19 |
2024-01-25 |
BioLegend, Inc. |
Anti-cd157 antibodies, antigen-binding fragments thereof and compositions and methods for making and using the same
|
WO2024040114A2
(en)
|
2022-08-18 |
2024-02-22 |
BioLegend, Inc. |
Anti-axl antibodies, antigen-binding fragments thereof and methods for making and using the same
|
WO2024192033A1
(en)
|
2023-03-13 |
2024-09-19 |
Regeneron Pharmaceuticals, Inc. |
Combination of pd-1 inhibitors and lag-3 inhibitors for enhanced efficacy in treating melanoma
|
CN118243913B
(zh)
*
|
2024-05-29 |
2024-08-23 |
上海秤信生物科技有限公司 |
一种质控品保存液及其应用
|