ATE473742T1 - Kondensierte triazolderivate als dipeptidylpeptidase-iv-hemmer zur behandlung bzw. prävention von diabetes - Google Patents
Kondensierte triazolderivate als dipeptidylpeptidase-iv-hemmer zur behandlung bzw. prävention von diabetesInfo
- Publication number
- ATE473742T1 ATE473742T1 AT05788858T AT05788858T ATE473742T1 AT E473742 T1 ATE473742 T1 AT E473742T1 AT 05788858 T AT05788858 T AT 05788858T AT 05788858 T AT05788858 T AT 05788858T AT E473742 T1 ATE473742 T1 AT E473742T1
- Authority
- AT
- Austria
- Prior art keywords
- diabetes
- inhibitors
- prevention
- treatment
- triazole derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60372704P | 2004-08-23 | 2004-08-23 | |
PCT/US2005/029591 WO2006023750A2 (en) | 2004-08-23 | 2005-08-19 | Fused triazole derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE473742T1 true ATE473742T1 (de) | 2010-07-15 |
Family
ID=35968217
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05788858T ATE473742T1 (de) | 2004-08-23 | 2005-08-19 | Kondensierte triazolderivate als dipeptidylpeptidase-iv-hemmer zur behandlung bzw. prävention von diabetes |
Country Status (9)
Country | Link |
---|---|
US (1) | US7625888B2 (de) |
EP (1) | EP1784188B1 (de) |
JP (1) | JP2008510810A (de) |
CN (1) | CN101005877A (de) |
AT (1) | ATE473742T1 (de) |
AU (1) | AU2005277283A1 (de) |
CA (1) | CA2576465A1 (de) |
DE (1) | DE602005022320D1 (de) |
WO (1) | WO2006023750A2 (de) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602004018503D1 (de) | 2003-07-31 | 2009-01-29 | Merck & Co Inc | Hexahydrodiazepinone als inhibitoren des dipeptidylpeptidase-iv zur behandlung bzw. prävention von diabetes |
JP2007536234A (ja) | 2004-05-04 | 2007-12-13 | メルク エンド カムパニー インコーポレーテッド | 糖尿病の治療又は予防のためのジペプチジルペプチダーゼ−iv阻害剤としての1,2,4−オキサジアゾール誘導体 |
JP2007538079A (ja) | 2004-05-18 | 2007-12-27 | メルク エンド カムパニー インコーポレーテッド | 糖尿病の治療又は予防のためのジペプチジルペプチダーゼ−iv阻害剤としてのシクロヘキシルアラニン誘導体 |
EP1921917B1 (de) * | 2005-08-26 | 2012-03-21 | Merck Sharp & Dohme Corp. | Kondensierte aminopiperidine als dipeptidylpeptidase-iv-inhibitoren zur behandlung oder prävention von diabetes |
US8173642B2 (en) | 2005-10-25 | 2012-05-08 | Shionogi & Co., Ltd. | Aminodihydrothiazine derivatives |
PE20071221A1 (es) | 2006-04-11 | 2007-12-14 | Arena Pharm Inc | Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas |
EP2089383B1 (de) | 2006-11-09 | 2015-09-16 | Probiodrug AG | 3-hydroxy-1,5-dihydropyrrol-2-one derivate als inhibitoren von glutaminylcyclase zur behandlung von geschwüren, krebs und anderen krankheiten |
WO2008060488A1 (en) * | 2006-11-14 | 2008-05-22 | Merck & Co., Inc. | Tricyclic heteroaromatic compounds as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes |
US9126987B2 (en) | 2006-11-30 | 2015-09-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
US8546394B2 (en) * | 2007-04-17 | 2013-10-01 | Bristol-Myers Squibb Company | Substituted [1,2,4]triazolo[4,3-A]pyrazine 11-beta-hydroxysteroid dehydrogenase inhibitors |
US9656991B2 (en) | 2007-04-18 | 2017-05-23 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
WO2008133273A1 (ja) | 2007-04-24 | 2008-11-06 | Shionogi & Co., Ltd. | アルツハイマー症治療用医薬組成物 |
BRPI0811034A2 (pt) | 2007-04-24 | 2014-12-09 | Shionogi & Co | Derivados de aminodi-hidrotiazina substituídos com um grupo cíclico e seus usos e composições farmacêuticas |
CN101486689B (zh) * | 2008-01-18 | 2011-08-10 | 山东轩竹医药科技有限公司 | 具有磺酰胺基甲酰胺哌嗪结构的dpp-iv抑制剂 |
EP2108960A1 (de) | 2008-04-07 | 2009-10-14 | Arena Pharmaceuticals, Inc. | Verfahren zur Verwendung eines A G Protein-gekoppelten Rezeptors zur Identifikation von Peptid YY (PYY) Sekretagoga und nützliche Verbindungen zur Behandlung von durch (PYY) Sekretagoga modulierten Zuständen und nützliche Verbindungen zur Behandlung von Zuständen durch PYY |
ES2738123T3 (es) | 2008-06-13 | 2020-01-20 | Shionogi & Co | Derivado heterocíclico que contiene azufre que tiene actividad inhibitoria de ß-secretasa |
CN102186841A (zh) | 2008-10-22 | 2011-09-14 | 盐野义制药株式会社 | 具有bace1抑制活性的2-氨基嘧啶-4-酮及2-氨基吡啶衍生物 |
LT2464645T (lt) | 2009-07-27 | 2017-10-25 | Gilead Sciences, Inc. | Kondensuoti heterocikliniai junginiai, kaip jonų kanalų moduliatoriai |
JP5934645B2 (ja) | 2009-09-11 | 2016-06-15 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのヘテロ環式誘導体 |
CN102834384A (zh) | 2009-12-11 | 2012-12-19 | 盐野义制药株式会社 | *嗪衍生物 |
US8853212B2 (en) | 2010-02-22 | 2014-10-07 | Merck Sharp & Dohme Corp | Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-IV inhibitors for the treatment of diabetes |
WO2011107530A2 (en) | 2010-03-03 | 2011-09-09 | Probiodrug Ag | Novel inhibitors |
SG183229A1 (en) | 2010-03-10 | 2012-09-27 | Probiodrug Ag | Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5) |
US8946223B2 (en) | 2010-04-12 | 2015-02-03 | Millennium Pharmaceuticals, Inc. | Substituted hydroxamic acids and uses thereof |
US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
EP2571876B1 (de) | 2010-05-21 | 2016-09-07 | Merck Sharp & Dohme Corp. | Substituierte siebenteilige heterozyklische verbindungen als dipeptidyl-peptidase-iv-hemmer zur behandlung von diabetes |
CA2802288C (en) | 2010-07-02 | 2018-08-21 | Gilead Sciences, Inc. | Triazolopyridinone compounds as ion channel modulators |
IN2010DE02164A (de) | 2010-09-13 | 2015-07-24 | Panacea Biotec Ltd | |
AU2011321427A1 (en) | 2010-10-29 | 2013-05-02 | Shionogi & Co., Ltd. | Naphthyridine derivative |
JP5766198B2 (ja) | 2010-10-29 | 2015-08-19 | 塩野義製薬株式会社 | 縮合アミノジヒドロピリミジン誘導体 |
EP2648517B1 (de) | 2010-12-06 | 2015-08-05 | Merck Sharp & Dohme Corp. | Trizyklische heterozyklen als dipeptidylpeptidase-iv-hemmer |
US8530670B2 (en) | 2011-03-16 | 2013-09-10 | Probiodrug Ag | Inhibitors |
US8883779B2 (en) | 2011-04-26 | 2014-11-11 | Shinogi & Co., Ltd. | Oxazine derivatives and a pharmaceutical composition for inhibiting BACE1 containing them |
MX361350B (es) | 2011-05-10 | 2018-12-04 | Gilead Sciences Inc | Compuestos heterocíclicos fusionados como moduladores del canal de sodio. |
CN103702562A (zh) | 2011-06-29 | 2014-04-02 | 默沙东公司 | 用于制备手性二肽基肽酶-iv抑制剂的方法 |
TWI622583B (zh) | 2011-07-01 | 2018-05-01 | 基利科學股份有限公司 | 作為離子通道調節劑之稠合雜環化合物 |
NO3175985T3 (de) | 2011-07-01 | 2018-04-28 | ||
EP2729468A4 (de) | 2011-07-05 | 2015-03-18 | Merck Sharp & Dohme | Tricyclische heterozyklen als dipeptidylpeptidase-iv-hemmer |
WO2013013833A1 (en) | 2011-07-27 | 2013-01-31 | Farma Grs, D.O.O. | Process for the preparation of sitagliptin and its pharmaceutically acceptable salts |
US9073930B2 (en) | 2012-02-17 | 2015-07-07 | Merck Sharp & Dohme | Dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes |
US9156848B2 (en) | 2012-07-23 | 2015-10-13 | Merck Sharp & Dohme Corp. | Treating diabetes with dipeptidyl peptidase-IV inhibitors |
WO2014018350A1 (en) | 2012-07-23 | 2014-01-30 | Merck Sharp & Dohme Corp. | Treating diabetes with dipeptidyl peptidase-iv inhibitors |
US9540359B2 (en) | 2012-10-24 | 2017-01-10 | Shionogi & Co., Ltd. | Dihydrooxazine or oxazepine derivatives having BACE1 inhibitory activity |
JO3773B1 (ar) | 2013-03-14 | 2021-01-31 | Janssen Pharmaceutica Nv | معدلات p2x7 |
ES2666155T3 (es) | 2013-03-14 | 2018-05-03 | Janssen Pharmaceutica Nv | Moduladores de P2X7 |
ES2689526T3 (es) | 2013-03-14 | 2018-11-14 | Janssen Pharmaceutica Nv | Moduladores de P2X7 |
TWI627174B (zh) | 2013-03-14 | 2018-06-21 | 比利時商健生藥品公司 | P2x7調控劑 |
JP6574474B2 (ja) | 2014-07-21 | 2019-09-11 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | キラルジペプチジルペプチダーゼ−iv阻害剤の製造方法 |
ES2714048T3 (es) | 2014-09-12 | 2019-05-24 | Janssen Pharmaceutica Nv | Moduladores de P2X7 |
EP3461819B1 (de) | 2017-09-29 | 2020-05-27 | Probiodrug AG | Hemmer der glutaminylcyclase |
CN115772120A (zh) | 2017-12-25 | 2023-03-10 | 住友化学株式会社 | 杂环化合物和含有该杂环化合物的有害节肢动物防除剂 |
CN113164458B (zh) | 2018-09-28 | 2024-09-13 | 詹森药业有限公司 | 单酰基甘油脂肪酶调节剂 |
CN113164459B (zh) | 2018-09-28 | 2024-09-03 | 詹森药业有限公司 | 单酰基甘油脂肪酶调节剂 |
WO2020158889A1 (ja) | 2019-01-31 | 2020-08-06 | 住友化学株式会社 | 複素環化合物及びそれを含有する有害節足動物防除組成物 |
PE20220376A1 (es) * | 2019-06-06 | 2022-03-16 | Hutchison Medipharma Ltd | Compuestos triciclicos y su uso |
KR20220075386A (ko) | 2019-09-30 | 2022-06-08 | 얀센 파마슈티카 엔.브이. | 방사성 표지된 mgl pet 리간드 |
KR20220157999A (ko) | 2020-03-26 | 2022-11-29 | 얀센 파마슈티카 엔.브이. | 모노아실글리세롤 리파아제 조절제 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6470096A (en) | 1995-07-19 | 1997-02-18 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused triazole compounds |
DE60226723D1 (de) | 2001-03-27 | 2008-07-03 | Merck & Co Inc | Dipeptidylpeptidase-hemmer für die behandlung oder prävention von diabetes |
AU2002344820B2 (en) | 2001-06-20 | 2006-12-14 | Merck & Co., Inc. | Dipeptidyl peptidase inhibitors for the treatment of diabetes |
EP1406622B1 (de) | 2001-06-20 | 2006-02-22 | Merck & Co., Inc. | Dipeptidylpeptidase-hemmer zur behandlung von diabetes |
UA74912C2 (en) | 2001-07-06 | 2006-02-15 | Merck & Co Inc | Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes |
DE60316416T2 (de) | 2002-03-25 | 2008-06-26 | Merck & Co., Inc. | Heterocyclische beta-aminoverbindungen als inhibitoren der dipeptidylpeptidase zur behandlung bzw. prävention von diabetes |
JP4530852B2 (ja) | 2002-07-15 | 2010-08-25 | メルク・シャープ・エンド・ドーム・コーポレイション | 糖尿病治療のためのピペリジノピリミジンジペプチジルペプチダーゼ阻害剤 |
WO2004032836A2 (en) | 2002-10-07 | 2004-04-22 | Merck & Co., Inc. | Antidiabetic beta-amino heterocylcic dipeptidyl peptidase inhibitors |
PL216527B1 (pl) | 2002-10-18 | 2014-04-30 | Merck & Co Inc | Związki ß-aminoheterocykliczne i kompozycja farmaceutyczna |
CA2504735C (en) | 2002-11-07 | 2009-06-23 | Merck & Co., Inc. | Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
WO2004050022A2 (en) | 2002-12-04 | 2004-06-17 | Merck & Co., Inc. | Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
CA2508947A1 (en) | 2002-12-20 | 2004-07-15 | Merck & Co., Inc. | 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
WO2004064778A2 (en) | 2003-01-17 | 2004-08-05 | Merck & Co. Inc. | 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
US7388019B2 (en) | 2003-01-31 | 2008-06-17 | Merck & Co., Inc. | 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
DE602004026440D1 (de) | 2003-06-06 | 2010-05-20 | Merck Sharp & Dohme | Kondensierte indole als dipeptidyl-peptidase-hemmer zur behandlung oder prävention von diabetes |
EP1638950A4 (de) | 2003-06-17 | 2010-06-30 | Merck Sharp & Dohme | Cyclohexylglycinderivate als dipeptidylpeptidaseinhibitoren zur behandlung bzw. prevention von diabetes |
DE602004018503D1 (de) | 2003-07-31 | 2009-01-29 | Merck & Co Inc | Hexahydrodiazepinone als inhibitoren des dipeptidylpeptidase-iv zur behandlung bzw. prävention von diabetes |
AU2004286857A1 (en) | 2003-11-04 | 2005-05-19 | Merck & Co., Inc. | Fused phenylalanine derivatives as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes |
JP2007536234A (ja) | 2004-05-04 | 2007-12-13 | メルク エンド カムパニー インコーポレーテッド | 糖尿病の治療又は予防のためのジペプチジルペプチダーゼ−iv阻害剤としての1,2,4−オキサジアゾール誘導体 |
JP2007538079A (ja) | 2004-05-18 | 2007-12-27 | メルク エンド カムパニー インコーポレーテッド | 糖尿病の治療又は予防のためのジペプチジルペプチダーゼ−iv阻害剤としてのシクロヘキシルアラニン誘導体 |
US7411093B2 (en) | 2004-12-20 | 2008-08-12 | Hoffman-La Roche Inc. | Aminocycloalkanes as DPP-IV inhibitors |
RU2396257C2 (ru) | 2004-12-20 | 2010-08-10 | Ф.Хоффманн-Ля Рош Аг | Производные 4-аминопиперидина |
-
2005
- 2005-08-19 AT AT05788858T patent/ATE473742T1/de not_active IP Right Cessation
- 2005-08-19 EP EP05788858A patent/EP1784188B1/de not_active Not-in-force
- 2005-08-19 AU AU2005277283A patent/AU2005277283A1/en not_active Abandoned
- 2005-08-19 DE DE602005022320T patent/DE602005022320D1/de active Active
- 2005-08-19 CA CA002576465A patent/CA2576465A1/en not_active Abandoned
- 2005-08-19 US US11/660,130 patent/US7625888B2/en not_active Expired - Fee Related
- 2005-08-19 CN CNA200580028653XA patent/CN101005877A/zh active Pending
- 2005-08-19 JP JP2007529987A patent/JP2008510810A/ja not_active Withdrawn
- 2005-08-19 WO PCT/US2005/029591 patent/WO2006023750A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2006023750A3 (en) | 2006-07-27 |
EP1784188A4 (de) | 2009-06-24 |
CA2576465A1 (en) | 2006-03-02 |
US20070208010A1 (en) | 2007-09-06 |
EP1784188A2 (de) | 2007-05-16 |
AU2005277283A1 (en) | 2006-03-02 |
EP1784188B1 (de) | 2010-07-14 |
US7625888B2 (en) | 2009-12-01 |
WO2006023750A2 (en) | 2006-03-02 |
DE602005022320D1 (de) | 2010-08-26 |
JP2008510810A (ja) | 2008-04-10 |
CN101005877A (zh) | 2007-07-25 |
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