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ATE470708T1 - Hyaluronansynthase-gene und expression davon - Google Patents

Hyaluronansynthase-gene und expression davon

Info

Publication number
ATE470708T1
ATE470708T1 AT02804804T AT02804804T ATE470708T1 AT E470708 T1 ATE470708 T1 AT E470708T1 AT 02804804 T AT02804804 T AT 02804804T AT 02804804 T AT02804804 T AT 02804804T AT E470708 T1 ATE470708 T1 AT E470708T1
Authority
AT
Austria
Prior art keywords
expression
synthase genes
host cell
bacillus host
hyaluronic
Prior art date
Application number
AT02804804T
Other languages
English (en)
Inventor
Paul L Deangelis
Paul Weigel
Kshama Kumari
Original Assignee
Univ Oklahoma State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Oklahoma State filed Critical Univ Oklahoma State
Application granted granted Critical
Publication of ATE470708T1 publication Critical patent/ATE470708T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT02804804T 2001-06-13 2002-06-13 Hyaluronansynthase-gene und expression davon ATE470708T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29778801P 2001-06-13 2001-06-13
US29774401P 2001-06-13 2001-06-13
PCT/US2002/018915 WO2003060063A2 (en) 1999-12-21 2002-06-13 Hyaluronan synthase genes and expression thereof

Publications (1)

Publication Number Publication Date
ATE470708T1 true ATE470708T1 (de) 2010-06-15

Family

ID=31498148

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02804804T ATE470708T1 (de) 2001-06-13 2002-06-13 Hyaluronansynthase-gene und expression davon

Country Status (10)

Country Link
EP (1) EP1481052B1 (de)
JP (1) JP2005514059A (de)
CN (2) CN1620511A (de)
AT (1) ATE470708T1 (de)
AU (2) AU2002365206B2 (de)
CA (1) CA2451443C (de)
DE (1) DE60236688D1 (de)
DK (1) DK1481052T3 (de)
ES (1) ES2346196T3 (de)
WO (1) WO2003060063A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008200910C1 (en) * 2001-12-21 2012-11-22 Novozymes A/S Methods for producing hyaluronan in a recombinant host cell
DK1572895T3 (da) 2001-12-21 2011-07-11 Novozymes Biopharma Dk As Fremgangsmåder til fremstilling af hyaluronan i en rekombinant værtscelle
EP1735455A2 (de) * 2004-03-31 2006-12-27 Novozymes Biopolymer A/S Verfahren zur produktion von hyaluronsäure in einer bacillus-zelle
EP1696032A1 (de) 2005-02-23 2006-08-30 Bayer CropScience GmbH Verfahren und Mittel zur Herstellung von Hyaluronan in Pilzen
JP4639904B2 (ja) 2005-03-30 2011-02-23 チッソ株式会社 蛍光活性を有するルシフェラーゼの活性増強方法
JP4609177B2 (ja) 2005-04-28 2011-01-12 チッソ株式会社 カルシウム結合型発光蛋白質溶液の発光時間延長方法
US20080038780A1 (en) * 2006-02-15 2008-02-14 Novozymes Biopolymer A/S Production of low molecular weight hyaluronic acid
GB0610498D0 (en) * 2006-05-26 2006-07-05 Univ York Modified molecule
US20110281817A1 (en) * 2007-08-31 2011-11-17 Sugar Industry Innovation Pty. Ltd. Production of hyaluronic acid
CN102559559A (zh) * 2012-02-21 2012-07-11 山东福瑞达生物医药有限公司 一种芽孢杆菌及采用该菌种生产透明质酸酶的方法
WO2013123791A1 (zh) * 2012-02-21 2013-08-29 华熙福瑞达生物医药有限公司 一种芽孢杆菌、一种透明质酸酶、以及其用途
CN108587918A (zh) * 2018-05-30 2018-09-28 昆明理工大学 一种基于兼养微藻油脂积累的方法
CN108841862A (zh) * 2018-07-19 2018-11-20 中国农业科学院北京畜牧兽医研究所 一种含有ha蛋白融合标签的植物表达质粒载体及其载体的构建方法
CN111518736B (zh) 2019-10-24 2022-04-15 华熙生物科技股份有限公司 一种高效合成高纯度透明质酸及其寡聚糖的重组谷氨酸棒状杆菌
CN115315242A (zh) * 2020-04-22 2022-11-08 株式会社资生堂 透明质酸产生促进剂
EP4067499A1 (de) * 2021-04-01 2022-10-05 Givaudan SA Hyaluronsäureproduzierende rekombinante zellen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455304B1 (en) * 1994-07-01 2002-09-24 The Board Of Regents Of The University Of Oklahoma Hyaluronate synthase gene and uses thereof
US6492150B1 (en) * 1996-07-03 2002-12-10 Clear Colutions Biotech, Inc. Gene encoding hyaluronan synthase
BR9909346A (pt) * 1998-04-02 2001-09-11 Univ Oklahoma Segmento de ácido nucleico, vetor recombinante, célula hospedeira, composição, processos para detectar uma espécie de dna, uma célula bacteriana e infecção, para produzir ácido hialurÈnico e para criar uma vacina, sequência de ácido nucleico e de cdna, vacina e teste diagnóstico
AU2002359581B2 (en) * 2001-12-03 2008-01-10 The Board Of Regents Of The University Of Oklahoma Hyaluronan synthases and methods of making and using same
DK1572895T3 (da) * 2001-12-21 2011-07-11 Novozymes Biopharma Dk As Fremgangsmåder til fremstilling af hyaluronan i en rekombinant værtscelle

Also Published As

Publication number Publication date
WO2003060063A2 (en) 2003-07-24
JP2005514059A (ja) 2005-05-19
EP1481052B1 (de) 2010-06-09
AU2008202651B2 (en) 2011-06-02
CA2451443A1 (en) 2003-07-24
ES2346196T3 (es) 2010-10-13
DE60236688D1 (de) 2010-07-22
CA2451443C (en) 2013-05-28
AU2002365206A1 (en) 2003-07-30
CN1620511A (zh) 2005-05-25
EP1481052A4 (de) 2005-11-16
WO2003060063A3 (en) 2004-09-16
CN101709285B (zh) 2014-03-26
AU2002365206B2 (en) 2008-03-20
AU2008202651A1 (en) 2008-07-10
EP1481052A2 (de) 2004-12-01
DK1481052T3 (da) 2010-09-20
CN101709285A (zh) 2010-05-19

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